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A novel mortality risk score for emphysematous pyelonephritis:A multicenter study of the Global Research in the Emphysematous Pyelonephritis group

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Current Urology 2024年第1期18卷 55-60页

作者： Hegel Trujillo-Santamaría José Iván Robles-Torres Jeremy Yuen-Chun Teoh Yiloren Tanidir José Gadú Campos-Salcedo Edgar Iván Bravo-Castro Marcelo Langer Wroclawski W.S.Yeoh Santosh Kumar juan eduardo sanchez-nuñez José Enrique Espinoza-Aznar Deepak Ragoori Saeed Bin Hamri Ong Teng Aik Cecil Paul Tarot-Chocooj Anil Shrestha Mohamed Amine Lakmichi Mateus Cosentino-Bellote Luis Gabriel Vázquez-Lavista Boukary Kabre Ho Yee Tiong José Gustavo Arrambide-Herrera Lauro Salvador Gómez-Guerra Umut Kutukoglu Joao Arthur Brunhara Alves-Barbosa Jorge Jaspersen Christian Acevedo Francisco Virgen-Gutiérrez Sumit Agrawal Hugo Octaviano Duarte-Santos Chai Chu Ann Daniele Castellani Vineet Gahuar Department of Urology Hospital CovadongaCórdobaMéxico Department of Urology Hospital Universitario"Dr.José Eleuterio Gonzalez"MonterreyMéxico Department of Surgery S.H.Ho Urology CentrePrince of Wales HospitalThe Chinese University of Hong KongHong KongChina Department of Urology Marmara University School of MedicineIstanbulTurkey Department of Urology Hospital Central MilitarMéxico CityMéxico Department of Urology Hospital Israelita Albert EinsteinBP-a Beneficência Portuguesa de Sao PauloSao PauloBrazil Faculdade de Medicina do ABC Santo AndréBrazil Department of Urology University Surgical ClusterNational University HospitalSingaporeSingapore Department Urology Christian Medical CollegeVelloreTamilnadIndia Department Urology Hospital General de México"Dr.Eduardo Liceaga"México CityMéxico Department of Urology Hospital Regional de Alta Especialidad de la Peninsula de YucatánMéridaMéxico Department Urology Asian Institute of Nephrology and UrologyHyderabadIndia Department Urology King Abdulaziz National Guard HospitalRiyadhSaudi Arabia Division of Urology Department of SurgeryUniversity of MalayaKuala LumpurMalaysia Department of Urology Central Military HospitalMexico CityMexico National Academy of Medical Sciences Bir Hospital and B&B HospitalGwarko LalitpurNepal Department of Urology University Hospital Mohammed theⅥ^(th)of MarrakeshMarrakeshMorocco Department of Urology Federal University of ParanáSchool of MedicineHospital das ClínicasCuritibaBrazil Department of Urology Hospital Médica SurMexico CityMexico Department of Urology Hospital Yalgado Ouedraogo OuagadougaKadiogoBurkina Faso Department of Urology Hospital Das Clínicas da Universidade de Sao PauloSao PauloBrazil Department of Urology AIIMSBhubaneshwarIndia Department of Urology Hospital Municipal Dr.Moysés Deutsch(M'Boi Mirim)Sao PauloBrazil Department of Urology Azienda Ospedaliero-Universitaria Ospedali Riuniti di AnconaPolytechnic University of Le Marche RegionAnconaItaly Department of Minim

Background:Emphysematous pyelonephritis(EPN)is a necrotizing infection of the kidney and the surrounding tissues associated with considerable *** aimed to formulate a score that classifies the risk of mortality in patients with EPN at hospital *** and methods:Patients diagnosed with EPN between 2013 and 2020 were retrospectively *** from 15 centers(70%)were used to develop the scoring system,and data from 7 centers(30%)were used to validate *** and mułtivariable logistic regression analyses were performed to identify independent factors related to *** operating characteristic curve analysis was performed to construct the sconng system and calculate the risk of mortality.A standardized regression coefficient was used to quantify the discriminating power of each factor to convert the individual coefficients into *** area under the curve was used to quantify the scoring system *** 8-point scoring system for the mortality risk was created(range,0-7).Results:In total,570 patients were included(400 in the test group and 170 in the validation group).Independent predictors of mortality in the multivariable logistic regression were included in the scoring system:quick Sepsis-related Organ Failure Assessment score≥2(2 points),anemia,paranephric gas extension,leukocyte count>22,000/pL,thrombocytopenia,and hyperglycemia(1 point each).The mortality rate was<5%for scores≤3,83.3%for scores 6,and 100%for scores *** area under the Curve was 0.90(95%confidence interval,0.84-0.95)for test and 0.91(95%confidence interval,0.84-0.97)for the validation ***:Our score predicts the risk of mortality in patients with EPN at presentation and may help clinicians identify patients at a higher risk of death.

关键词： Emphysematous pyelonephritis Mortality Prognosis

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Transmission line protection challenges influenced by inverter-based resources:a review

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Protection and Control of Modern Power Systems 2022年第1期7卷 406-422页

作者： juan Carlos Quispe eduardo Orduña Institute of Electrical and Energy-CONICET Universidad Nacional de San JuanSan JuanArgentina Universidad Tecnológica del Perú LimaPeru

High penetration of renewable energy sources(RES)leads to new challenges for protection *** schemes are typically designed according to the dynamic behavior of rotating machines as generation sources,while the RES dynamic response,mainly governed by inverters,is not ***,some relevant algorithms of transmission line protection are experiencing challenges because of the fact that magnitude and phase angle com-parison,amount of negative-sequence,and short-circuit current level are affected by the ***,an in-depth study of this issue is necessary,one which considers the main causes and new methodological criteria *** work presents an extensive literature review of the evaluation of electrical protection performance and the effects of RES connected to a power grid through *** data on many representative publications related to this topic are obtained to show the current research lines and their proposed *** addition,this work identi-fies the main protection functions affected and describes the new protection schemes that consider ***,an analysis and discussion of the selected bibliography are presented.

关键词： Inverter-based resources Inverter control system Photovoltaic plant Transmission line protection Wind farm

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Malignant transformation of hepatocellular adenoma in a young female patient after ovulation induction fertility treatment:A case report

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World Journal of Gastrointestinal Surgery 2019年第4期11卷 229-236页

作者： juan Glinka Rodrigo sanchez Clariá Eugenia Fratanoni juan Spina eduardo Mullen Victoria Ardiles Oscar Mazza juan Pekolj Martín de Santiba?es eduardo de Santiba?es Department of General Surgery Hepatobilio-pancreatic Unit Hospital Italiano de Buenos Aires Department of Radiology Hospital Italiano de Buenos Aires Department of Surgical Pathology Hospital Italiano de Buenos Aires

BACKGROUND Hepatocellular adenoma(HCA) is a rare benign liver tumor usually affecting young women with a history of prolonged use of hormonal *** the majority is asymptomatic, a low proportion may have significant complications such as bleeding or malignancy. Despite responding to the hormonal stimulus, the desire for pregnancy in patients with small HCA is not contraindicated. However, through this work we demonstrate that intensive hormonal therapies such as those used in the treatment of infertility can trigger serious complications CASE SUMMARY A 33-year-old female with a 10-year history of oral contraceptive use was diagnosed with a hepatic tumor as an incidental finding in an abdominal ultrasound. The patient showed no symptoms and physical examination was unremarkable. Laboratory functional tests were within normal limits and tests for serum tumor markers were negative. An abdominal magnetic resonance imaging(MRI) was performed, showing a 30 mm × 29 mm focal lesion in segment VI of the liver compatible with HCA or Focal Nodular Hyperplasia with atypical behavior. After a total of six years of follow-up, the patient underwent ovulation induction treatment for infertility. On a following MRI, a suspected malignancy was warned and hence, surgery was decided. The surgical specimen revealed malignant transformation of HCA towards trabecular hepatocarcinoma with dedifferentiated areas. There was non-evidence of tumor recurrence after three years of clinical and imaging follow-up.,CONCLUSION HCAs can be malignant regardless its size and low-risk appearance on MRI when an ovultation induction therapy is indicated.

关键词： Hepatocellular adenoma Malignant transformation Focal liver lesion Adenoma Ovulation induction Case report

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Constraining the timing of the India-Asia continental collision by the sedimentary record

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Science China Earth Sciences 2017年第4期60卷 603-625页

作者： HU XiuMian WANG JianGang AN Wei eduardo GARZANTI LI juan State Key Laboratory of Mineral Deposits Research School of Earth Sciences and EngineeringNanjing University Institute of Geology and Geophysics Chinese Academy of Sciences School of Resources and Environmental Engineering Hefei University of Technology Laboratory for Provenance Studies Department of Earth and Environmental SciencesUniversita di Milano-Bicocca

Placing precise constraints on the timing of the India-Asia continental collision is essential to understand the successive geological and geomorphological evolution of the orogenic belt as well as the uplift mechanism of the Tibetan Plateau and their effects on climate,environment and *** on the extensive study of the sedimentary record on both sides of the Yarlung-Zangbo suture zone in Tibet,we review here the present state of knowledge on the timing of collision onset,discuss its possible diachroneity along strike,and reconstruct the early structural and topographic evolution of the Himalayan collided *** define continent-continent collision as the moment when the oceanic crust is completely consumed at one point where the two continental margins come into *** use two methods to constrain the timing of collision onset:(1) dating the provenance change from Indian to Asian recorded by deep-water turbidites near the suture zone,and(2) dating the age of unconformities on both sides of the suture *** first method allowed us to constrain precisely collision onset as middle Palaeocene(59±l Ma).Marine sedimentation persisted in the collisional zone for another 20-25 Ma locally in southern Tibet,and molassic-type deposition in the Indian foreland basin did not begin until another 10-15 Ma *** sedimentary evidence failed to firmly document any significant diachroneity of collision onset from the central Himalaya to the western Himalaya and Pakistan so *** on the Cenozoic stratigraphic record of the Tibetan Himalaya,four distinct stages can be identified in the early evolution of the Himalayan orogen:(1) middle Palaeocene-early Eocene earliest Eohimalayan stage(from 59 to 52 Ma):collision onset and filling of the deep-water trough along the suture zone while carbonate platform sedimentation persisted on the inner Indian margin;(2) early-middle Eocene early Eohimalayan stage(from 52 to 41 or 35 Ma):filling of intervening seaways and

关键词： India-Asia continental collision Timing of collision onset Himalayan orogeny Tibet Himalaya Sedimentary record

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Liver graft procurement in neurologically deceased donor:Hospital Italiano of Buenos Aires approach

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Hepatobiliary & Pancreatic Diseases International 2022年第1期21卷 80-82页

作者： juan Glinka Carolina Vanetta juan Pekolj juan Mattera eduardo de Santibañes Martín de Santibañes Department of General Surgery Hospital Italiano de Buenos AiresBuenos AiresArgentina Section of HPB Surgery&Liver Transplantation Unit Hospital Italiano de Buenos AiresBuenos AiresArgentina

To the Editor:Liver procurement(LP)from a neurologically deceased donor(NDD)is one of the most important spotlights in liver transplanta-tion(LT)[1,2].The commonly used approaches include the“rapid”en-bloc dissection,the in vivo normothermic dissection,or a com-bination of both,according to the preferences and/or the experi-ence of the LP/LT team.A correct LP is essential to achieve optimal *** the counterpart,defective execution of any of its steps can leave the liver graft unusable and/or cause severe complica-tions in the recipient[3].

关键词： Liver neurological dissection

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Preoperative portal vein embolization followed by right hepatectomy to treat a complex common bile duct injury in a 5-year-old child

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World Journal of Pediatric Surgery 2019年第2期2卷 29-32页

作者： juan Glinka Rocio Bruballa Martin de Santibañes Rodrigo sanchez Clariá Victoria Ardiles Oscar María Mazza juan Pekolj eduardo de Santibañes Department of General Surgery Hepato-bilio-pancreatic and Liver Transplantation UnitHospital Italiano de Buenos AiresBuenos AiresArgentina

background Common bile duct injuries(CBDIs)remains a rare but serious complication in children undergoing laparoscopic cholecystectomy(LC),with an incidence of 0.44%.In severe lesions,a major liver resection may be necessary as a definitive *** current principles for safe hepatectomy are mainly focused on the liver parenchyma that remains after ***,one of the main factors related to posthepatectomy hepatic insufficiency is the quantity and quality of the future liver remnant(FLR).To achieve an optimal FLR,techniques such as portal vein embolization(PVE)are *** presentation We present the case of a 5-year-old child with a severe CBDI after LC,treated with preoperative PVE followed by a right hepatectomy as definitive *** reports of liver resections and PVE are described in the literature concerning the pediatric population.

关键词： hepatectomy bile injuries

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Time-frequency multiresolution of fault-generated transient signals in transmission lines using a morphological filter

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Protection and Control of Modern Power Systems 2023年第2期8卷 85-98页

作者： juan Carlos Quispe John Morales eduardo Orduna Carlo Liebermann Michael Bruhns Peter Schegner Universidad Nacional de San juan-CONICET San JuanArgentina Universidad Tecnológica del Perú LimaPerú Technical University of Dresden DresdenGermany

The ongoing transformation of electrical power systems highlights the weaknesses of the protection schemes of traditional devices because they are designed and configured according to traditional characteristics of the ***,this work proposes a new methodology to study the fault-generated high frequency transient signals in transmission lines through multiresolution *** high frequency components are determined by a new digital filtering technique based on mathematical morphology theory and a spectral energy ***,wide spectra of signals in the time–frequency domain are *** performance of this method is verified on an electrical power system modeled in ATP-Draw,where simulation and test signals are developed for different locations,fault resistances,inception angles,high frequency noises,sampling frequencies,types of faults,and shapes of the structuring *** results show the characteristics of the fault such as the traveling wave frequency,location,and starting time.

关键词： Digital filter High frequency Mathematical morphology Time–frequency Traveling waves

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The role of associating liver partition and portal vein ligation for staged hepatectomy in the management of patients with colorectal liver metastasis

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Hepatobiliary Surgery and nutrition 2020年第6期9卷 694-704页

作者： juan Glinka Victoria Ardiles juan Pekolj eduardo de Santibañes Martin de Santibañes Department of General Surgery Hepato-Bilio-Pancreatic&Liver Transplantation Unit Hospital Italiano de Buenos AiresBuenosAiresArgentina

Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)approach emerged as a promising surgical strategy for rapid and large hypertrophy of the future liver remnant(FLR)when a major liver resection is *** liver metastasis(CRLM)is their main ***,the promising results published so far,are very difficult to interpret since they usually focus on the technique and not on the underlying ***,they are usually made up of complex populations,which received different chemotherapy schemes,with the ALPPS technical variations implemented over time and without consistent long-term follow-up results as ***,its role in CRLM should be analyzed as carefully as possible to indicate and select the best candidates who will benefit the most from this *** conducted a computerized search using PubMed and Google Scholar for reports published so far,using mesh headings and keywords related to the ALPPS and CRLM.

关键词： Liver resection associating liver partition and portal vein ligation for staged hepatectomy(ALPPS) colorectal cancer metastasis liver regeneration

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Deadly oasis:Recurrent annihilation of Cretaceous desert bryophyte colonies;the role of solar,climate and lithospheric forcing

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Geoscience Frontiers 2021年第1期12卷 1-12页

作者： juan Pedro Rodríguez-Lópeza eduardo Barrón Daniel Peyrot Gary B.Hughes Department of Geology.Faculty of Science.United Arab Emirates University.50009.Al Ain Abu DhabiUnited Arab Emirates Instituto Geológico y Minero de Espana(IGME) Ríos Rosas 23E-28003MadridSpain School of Earth and Environment University of Western Australia.6101CrawleyWestern AustraliaAustralia Centre for Energy Geosciences University of Western Australia.6101CrawleyWestern AustraliaAustralia Physics Department University of CaliforniaSanta BarbaraCA93106USA

Many oases(wet interdunes)are sedimentary systems characterized by high-frequency water-level oscillations,marked changes in salinity and intense biological activity at their *** are considered to be one of the most challenging environments on Earth for ecosystem *** dynamic,depositional settings are usually unfavourable for fossilization and subsequent preservation of vegetal *** paper describes bryophyte(liverwort)assemblages occurring in three successive horizons interpreted to represent(i)recurrent early successional phases of biological soil crust colonization of wet interdune margins or(ii)exceptional preservation of floating or riparian liverworts in oasis pond waters associated with a progressive fall of the interdune water *** record of in situ colonization surfaces characterized by delicate(***-free)three-dimensional structures represents an exceptional type of preservation herein associated with a rapid variation in phreatic interdune water level and the subsequent establishment of anoxic and reducing *** occurrence of exceptionally preserved liverwort colonies coincides with the sedimentary record of,at least,three seismite levels in the *** gathered from the site suggests that the water table of the oasis was controlled by a combination of(i)a positive creation of accommodation space due to subsidence associated with movement on syn-sedimentary extensional faults,and(ii)the rise and fall of the oasis water table controlled by the oscillations of the groundwater system due to orbital changes which appear to drive the variability of the climate *** groundwater levels flooded the oasis soil crusts and lead to the exceptional recurrent preservation of liverwort colonies at the oasis ***,considering the hypothesis of floating or riparian liverworts in the oasis pond waters,the fall in the level of the oasis water table placed the floating liverworts in contact with the

关键词： Oasis Cretaceous Liverworts Colonies Extensional tectonics Solar cyclicity

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Differential responses to artificial selection on oviposition site preferences in Drosophila melanogaster and D. simulans

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Insect Science 2015年第6期22卷 821-828页

作者： eduardo M. Soto Maria I. L. Betti juan Hurtado Esteban Hasson Departamento de Ecologia Genetica y Evolucion IEGEBA (CONICET-UBA) Facultad de Ciencias Exactas y Naturales Universidad deBuenos Aires Buenos Aires Argentina

The preference-performance relationship in plant-insect interactions is a cen- tral theme in evolutionary ecology. Among many insects, eggs are vulnerable and larvae have limited mobility, making the choice of an appropriate oviposition site one of the most important decisions for a female. We investigated the evolution of oviposition preferences in Drosophila melanogaster Meigen and Drosophila simulans Sturtevant by artificially selecting for the preference for 2 natural resources, grape and quince. The main finding of our study is the differential responses of D. melanogaster and D. simulans. Although preferences evolved in the experimental populations of D. melanogaster, responses were not consistent with the selection regimes applied. In contrast, responses in D. simulans were consistent with expectations, demonstrating that this species has selectable genetic variation for the trait. Furthermore, crosses between D. simulans divergent lines showed that the genetic factors involved in grape preference appear to be largely recessive. In summary, our artificial selection study suggests that D. melanogaster and D. simulans possess different genetic architectures for this trait.

关键词： artificial selection behavior Drosophila genetic variation naturalresources oviposition preference

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