检索结果-南通市图书馆

The Immune System and the Role of Inflammation in Perinatal Depression

Neuroscience Bulletin 2016年第4期32卷 398-420页

作者： Philippe Leff-Gelman Ismael Mancilla-Herrera Monica Flores-Ramos Carlos Cruz-Fuentes juan Pablo Reyes-Grajeda maría del pilar garcía-cuétara Marielle Danitza Bugnot-perez David Ellioth Pulido-Ascencio National Institute of Perinatology Mexico City Mexico National Institute of Psychiatry Mexico City Mexico National Institute of Genomic Medicine Mexico CityMexico Faculty of Psychology Anahuac University HuixquilucanMexico National Council of Science and Technology Mexico CityMexico

Major depression during pregnancy is a common psychiatric disorder that arises from a complex and mul- tifactorial etiology. Psychosocial stress, sex, hormones, and genetic vulnerability increase the risk for triggering mood disorders. Microglia and toll-like receptor 4 play a crucial role in triggering wide and varied stress-induced responses mediated through activation of the inflammasome; this leads to the secretion of inflammatory cytokines, increased serotonin metabolism, and reduction of neurotransmitter availability along with hypothalamic-pituitary-adrenal axis hyperactivity. Dysregulation of this intricate neu- roimmune communication network during pregnancy modifies the maternal milieu, enhancing the emergence of depressive symptoms and negative obstetric and neu- ropsychiatric outcomes. Although several studies have clearly demonstrated the role of the innate immune system in major depression, it is still unclear how the placenta, the brain, and the monoaminergic and neuroendocrine systems interact during perinatal depression. Thus, in the present review we describe the cellular and molecular interactions between these systems in major depression during preg- nancy, proposing that the same stress-related mechanisms involved in the activation of the NLRP3 inflammasome in microglia and peripheral myeloid cells in depressed patients operate in a similar fashion in the neuroimmune placenta during perinatal depression. Thus, activation of Toll-like receptor 2 and 4 signaling and the NLRP3 inflammasome in placental immune cells may promote a shift of the Thl/Th2 bias towards a predominant Thl/Thl7 inflammatory response, associated with increased secretion of pro-inflammatory cytokines, among other secreted autocrine and paracrine mediators, which play a crucial role in triggering and/or exacerbating depressive symptoms during pregnancy.

关键词： Depression Pregnancy Immune systemInflammation Cytokine Serotonin Indoleamine dioxygenase Glucocorticoid Brain Placenta

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Botulinum Toxin A, Effect on Tensile Strength of Skin Wounds;Animal Study

引用

Journal of Biosciences and Medicines 2020年第2期8卷 17-24页

作者： Carlos A. Gonzalez-Alvarado juan Garzon-Muvdi Roxanna perez-Garmendia Victoria Ramirez Luz Graciela Cervantes Adriana Rodriguez-Gomez Rodrigo Davila-Diaz Cuahutemoc Marquez-Espriella Plastic and Reconstructive Surgery Division Hospital Central Sur de alta Especialidad de Petroleos Mexicanos Mexico City Mexico Experimental Surgery Department Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran Mexico City Mexico Pharmacology Department Instituto Nacional de Cardiologia Ignacio Chavez Mexico City Mexico Pathology Department Hospital Angeles del Pedregal Mexico City Mexico

Wound healing and cicatrization is a process that involves several phases. The main goal of a surgeon and specially the plastic surgeon is to achieve the best cosmetic results and avoid complications. Several tools are available to achieve the best result. One of the tools recently studied is the use of Botulinum toxin. The use of Botulinum toxin has showed to be a useful aid by improving macroscopic cosmetic changes, as histopathologic ones. The increase of the tensile strength is also one of the positive changes that come with the use of botulinum toxin.

关键词： Botulinum Toxin Wound Tensile Strength

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessing Healthcare Facilities Preparedness for Mass Fatalities Incident

引用

International Journal of Clinical Medicine 2013年第12期4卷 525-531页

作者： Marisol Pena-Orellana Ralph Rivera-Gutierrez juan AGonzalez-Sanchez Nilsa Padilla-Elias Heriberto Marin Centeno Hector Alonso-Serra Liza Millan-perez Patricia Monserrate-Vazquez Center for Public Health Preparedness Graduate School of Public HealthMedical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico Department of Health Services Administration Graduate School of Public HealthMedical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico Department of Emergency Medicine School of MedicineMedical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico

Background: Any healthcare facility must be prepared to handle a dramatic increase in deaths that can be produced by a catastrophic disaster. A mass fatality incident (MFI) will significantly increase the usual number of deaths that hospitals or forensic science services can manage on a daily basis. A survey was conducted to assess the hospital emergency department level of preparedness to deal with an MFI. Objective: To examine healthcare facilities level of preparedness for an MFI and morgue capacity. Methods: A total of 39 out of a sample of 44 hospitals participated in the study. Seven questionnaires were administered to explore: hospital general characteristics;emergency plans;equipment and infrastructure;collaborative agreements;personnel trainings;emergency communications;laboratory facilities;treatment protocols;security;and, epidemiologic surveillance. Results: Three-fourths (79.5%) of the healthcare facilities reported having a morgue, their average storage capacity was of three bodies. More than two-thirds (66.7%) of the institutions stated that they could not increase their morgue’s capacity. Most installations without a morgue do not possess an agreement with any other institution for the management of bodies. Hospitals have a very limited number of body bags utilized for the handling and transport of bodies. Conclusion: Most of healthcare facilities have morgues, but there are limitations with the current capacity and the lack of resources to increase their capacity in case of a disaster. Management of an MFI must be part of every hospital’s emergency plan, and must include collaborative agreements with forensic authorities, emergency management and public health agencies, and the community.

关键词： Hospitals Morgues Mass Casualties Mass Fatalities Puerto Rico

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SAXS and SANS Investigation of Synthetic Cholesteric Liquid-Crystal Polymers for Biomedical Applications

引用

材料科学与工程（中英文B版） 2013年第2期3卷 104-116页

作者： Mercedes perez Mendez Boualem Hammouda Institute of Polymer Science and Technology CSIC Juan de la Cierva Madrid 3 28006 Spain NIST Center for Neutron Research National Institute of Standards and Technology Gaithersburg 20899-6102 MD USA

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Structural and Optical Characterization of Indium Zinc Oxynitride Thin Films

引用

材料科学与工程（中英文A版） 2014年第3期4卷 91-98页

作者： Jose juan Ortega Sigala Maria Leticia perez Arrieta Hugo TototzintleHuitle Miguel Angel Aguilar Frutis Ciro Falcony Victor Hugo Mendez Garcia Jose de Jesus Araiza Ibarra Academic Unit of Physics UAZ Zacatecas C.P. 98060 Me~xico CIACyT UASLP San Luis Potosl C.P. 78210 Mexico CICATA 1PN Mexico D.F. C.P. 11500 Mexieo Department of Physics CINVESTA V IPN Mexico D.F. C.P. 07360 Mexico

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The importance of the bite angle of metal(Ⅲ) salen catalysts in the sequestration of CO_(2) with epoxides in mild conditions

引用

Green Chemical Engineering 2022年第2期3卷 180-187页

作者： Anna Vidal-Lopez Sergio Posada-perez Miquel Sola Valerio D'Elia Albert Poater Institut de Quimica Computacional i Catalisi and Departament de Quimica Universitat de GironaC/Maria Aurelia Capmany6917003GironaCataloniaSpain Department of Chemistry Universitat Autonoma de BarcelonaCerdanyola del VallesCatalonia08193Spain Department of Materials Science and Engineering School of Molecular Science and EngineeringVidyasirimedhi Institute of Science and Technology(VISTEC)21210PayupnaiWang ChanThailand

Located in the middle of the fever to solve the problem of CO_(2)emissions in the environment,CO_(2)sequestration by reaction with epoxides is one of the key tools,as it not only fixes CO_(2),but also makes it functional by leading to cyclic ***,the results are focused specifically on the formation of cyclic organic carbonates catalyzed by metal-salen complexes,previously achieved with yttrium and scandium,that are compared with those of analogous complexes containing metals from the first transition series,such as cobalt or *** functional theory(DFT)calculations allow to determine whether this switch of metals will be feasible and provide the basis for instigating future experimental efforts in this *** calculations analyzing the structure and electronics of the catalysts allow us to give not only a clear picture of whether these catalysts will be efficient,but also allow us to assess which metal center is the most convenient and/or whether the catalytic reaction will occur under mild *** buried volume calculations with the SambVca packages shed light on the different catalytic pockets of monometallic first row transition metals *** III salen *** predictive catalysis results show that the bite O-M-O angle plays an essential role in the catalysis.

关键词： CO_(2)fixation Salen catalyst CO_(2)functionalization Cyclic carbonate DFT calculations Predictive catalysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrated Multi-Head Self-Attention Transformer model for electricity demand prediction incorporating local climate variables

引用

Energy and AI 2023年第4期14卷 620-644页

作者： Sujan Ghimire Thong Nguyen-Huy Mohanad S.AL-Musaylh Ravinesh C.Deo David Casillas-perez Sancho Salcedo-Sanz School of Mathematics Physics and ComputingUniversity of Southern QueenslandSpringfieldQLD4300Australia Centre for Applied Climate Sciences University of Southern QueenslandToowoomba4350QLDAustralia Department of Information Technologies Management Technical CollegeSouthern Technical UniversityBasrah 61001Iraq Department of Signal Processing and Communications Universidad Rey Juan CarlosFuenlabrada28942MadridSpain Department of Signal Processing and Communications Universidad de AlcaláAlcaláde Henares28805MadridSpain

This paper develops a trustworthy deep learning model that considers electricity demand(G)and local climate *** model utilises Multi-Head Self-Attention Transformer(TNET)to capture critical information from𝐻,to attain reliable predictions with local climate(rainfall,radiation,humidity,evaporation,and maximum and minimum temperatures)data from Energex substations in Queensland,*** TNET model is then evaluated with deep learning models(Long-Short Term Memory LSTM,Bidirectional LSTM BILSTM,Gated Recurrent Unit GRU,Convolutional Neural Networks CNN,and Deep Neural Network DNN)based on robust model assessment *** Kernel Density Estimation method is used to generate the prediction interval(PI)of electricity demand forecasts and derive probability metrics and results to show the developed TNET model is accurate for all the *** study concludes that the proposed TNET model is a reliable electricity demand predictive tool that has high accuracy and low predictive errors and could be employed as a stratagem by demand modellers and energy policy-makers who wish to incorporate climatic factors into electricity demand patterns and develop national energy market insights and analysis systems.

关键词： Electricity demand forecasting Sustainable energy Artificial Intelligence Deep learning Transformer Networks Kernel Density Estimation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Reconstruction of lateral root formation through single-cell RNA sequencing reveals order of tissue in itiation

引用

Molecular Plant 2021年第8期14卷 1362-1378页

作者： Laura Serrano-Ron Pablo perez-Garcia Alvaro Sanchez-Corrionero Inmaculada Gude Javier Cabrera Pui-Leng Ip Kenneth D.Birnbaum Miguel A.Moreno-Risueno Centro de Biotecnologia y Genomica de Plantas Universidad Politecnica de Madrid(UPM)-lnstituto Naci on al de Investigacion y Tec no logia Agraria y Alimentaria(INIA)Pozuelo de Alarcon28223 MadridSpain Departamento de Biotecnologia-Biologia Vegetal Escuela Tecnica Superior de Ingenieria AgronomicaAlimentaria y de BiosistemasUniversidad Politecnica de Madrid(UPM)28040 MadridSpain Center for Genomics and Systems Biology Department of BiologyNew York UniversityNew YorkNYUSA

Postembryonic organogenesis is critical for plant ***,lateral roots(LRs)form the bulk of mature root systems,yet the ontogeny of the LR primordium(LRP)is not *** this study,we performed the single-cell RNA sequencing through the first four stages of LR formation in *** analysis led to a model in which a single group of precursor cells,with a cell identity different from their pericycle origins,rapidly reprograms and splits into a mixed ground tissue/stem cell niche fate and a vascular precursor *** ground tissue and stem cell niche fates soon separate and a subset of more specialized vascular cells form sucrose transporting phloem cells that appear to connect to the primary *** did not detect cells resembling epidermis or root cap,suggesting that outer tissues may form later,preceding LR *** this stage,some remaining initial precursor cells form the primordium flanks,while the rest create a reservoir of pluripotent cells that are able to replace the LR if *** ablation of the central and lateral LRP regions showed that remaining cells restart the sequence of tissue initiation to form a ***,our study reveals an ontological hierarchy for LR formation with an early and sequential split of main root tissues and stem cells.

关键词： organogenesis patterning stem cells single-cell RNA-seq cell fate regeneration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diversity of Emergency Codes in Hospitals

引用

International Journal of Clinical Medicine 2013年第11期4卷 499-503页

作者： Nilsa Padilla-Elias Marisol Pena-Orellana Ralph Rivera-Gutierrez juan AGonzalez-Sanchez Heriberto AMarin Centeno Hector Alonso-Serra Liza Millan-perez Patricia Monserrrate-Vazquez (Center for Public Health Preparedness)Graduate School of Public Health Medical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico (School of Medicine)Department of Emergency Medicine Medical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico Department of Health Services Administration Graduate School of Public HealthMedical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico

Background: Hospitals must be prepared to deal efficiently and effectively with different emergencies. To accomplish this, several countries have standardized their hospital emergency codes to improve their response capability. This is particularly important in Puerto Rico given that many health professionals, particularly physicians and nurses, provide services in more than one hospital. This study examined the emergency codes and alerts utilized in Puerto Rican hospitals. Objective: To assess hospitals’ level of emergency preparedness and response capability related to the variability of emergency codes and alerts utilized to respond to a situation in Puerto Rico. Method: A survey was conducted to characterize hospital emergency department level of preparedness and response to a mass fatality incident. A total of 39 out of a sample of 44 hospitals participated in the study. Semi-structured questionnaires were administered by the research team to members of each hospital’s administrative staff to explore the following: general hospital characteristics, emergency plans, emergency department capacity, collaborative agreements, personnel training, emergency communications, laboratory facilities, treatment protocols, security, epidemiologic surveillance, equipment and infrastructure. Results: Some hospitals in Puerto Rico use color coded emergency alerts, while others use key words or codes. Single color emergency codes can have different meanings in different hospitals. Conclusions: The findings clearly show that there is a lack of uniformity and clarity in the emergency codes utilized by hospitals in Puerto Rico. Single color codes have diverse meanings in different hospitals. This could adversely affect hospitals’ efficient and effective emergency response.

关键词： Communications Hospitals Health Health Communications Emergency Preparedness Preparedness Emergency Codes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Short-term effectiveness of high-and low-intensity percutaneous electrolysis in patients with patellofemoral pain syndrome:A pilot study

引用

World Journal of Orthopedics 2021年第10期12卷 781-790页

作者： juan Antonio Valera-Calero Alberto Sánchez-Mayoral-Martín Umut Varol Department of Physiotherapy Camilo Jose Cela UniversityMadrid 28692Spain Business Analytics and Big Data IE School of Human Sciences and TechnologyMadrid 28006Spain

BACKGROUND Unilateral patellofemoral pain syndrome(PFPS)is the most frequently diagnosed knee condition in populations aged0.05;tendon PPT immediate effects:F=0.15;η2=0.02;P>0.05 and tendon PPT 7-d effects:F=0.67;η2... 详细信息

关键词： Patellofemoral pain syndrome Electrolysis Myofascial pain syndromes Dry needling Clinical trial

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：