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Preparation and antibacterial activity of aromatic derivatives of β-aminopropionic and γ-aminobutyric acid

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chinese Journal of Chemistry 1997年第4期15卷 366-370页

作者： GUAN,Jing-Qu HU,Zun-ju ZOU,Zhi-Chen WU,Zhi-GuangDepartment of Chemistry,Shandong Teachers’ University,Jinan,Shandong 35001.,{1. Institute of Photographic Chemistry,{1. Academy of sciences,beijing 1.01.1.{1. Department of Chemistry Shandong Teachers' University Jinan Shandong 250014 China Institute of Photographic Chemistry Chinese Academy of Sciences Beijing 100101 China

Ten aromatic derivatives of β-aminopropionic acid and γ-aminobutyric acid were *** compositions and structures were identified by elemental analysis,IR,and 1. *** have been examined for their antibacterial action against Staphylococcua aurens and Escherichia *** compounds showed higher activity than the aromatic derivatives of ct-amino acid which were reported *** general conclusion to be drawn is that the distance between amino and carboxylic group in these molecules could affect their antibacterial ***,those compounds with p-methyl substituent in phenyl ring exhibit higher activity than the others,and all the compounds exhibit higher activity against Escherichia coli and against Staphylococcua aureus.

关键词： Antibacterial agent aromatic derivatives β-aminopropionic acid γ-aminobutyric acid

End-to-End Paired Ambisonic-Binaural Audio Rendering

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 502-513页

作者： Yin Zhu Qiuqiang Kong junjie Shi Shilei Liu Xuzhou Ye ju-Chiang Wang Hongming Shan junping Zhang Shanghai Key Laboratory of Intelligent Information Processing School of Computer ScienceFudan UniversityShanghai 200433China beijing ByteDance Technology Co.Ltd. Shanghai 201102China. chinese University of Hong Kong Hong KongChina IEEE Institute of Science and Technology for Brain-Inspired Intelligence and MOE Frontiers Center for Brain Science Fudan UniversityShanghai 200433 Shanghai Center for Brain Science and Brain-Inspired Technology Shanghai 200031China

Binaural rendering is of great interest to virtual reality and immersive media. Although humans can naturally use their two ears to perceive the spatial information contained in sounds, it is a challenging task for machines to achieve binaural rendering since the description of a sound field often requires multiple channels and even the metadata of the sound sources. In addition, the perceived sound varies from person to person even in the same sound field. Previous methods generally rely on individual-dependent head-related transferred function(HRTF)datasets and optimization algorithms that act on HRTFs. In practical applications, there are two major drawbacks to existing methods. The first is a high personalization cost, as traditional methods achieve personalized needs by measuring HRTFs. The second is insufficient accuracy because the optimization goal of traditional methods is to retain another part of information that is more important in perception at the cost of discarding a part of the information. Therefore, it is desirable to develop novel techniques to achieve personalization and accuracy at a low cost. To this end, we focus on the binaural rendering of ambisonic and propose 1. channel-shared encoder and channel-compared attention integrated into neural networks and 2. a loss function quantifying interaural level differences to deal with spatial information. To verify the proposed method, we collect and release the first paired ambisonic-binaural dataset and introduce three metrics to evaluate the content information and spatial information accuracy of the end-to-end methods. Extensive experimental results on the collected dataset demonstrate the superior performance of the proposed method and the shortcomings of previous methods.

关键词： Ambisonic attention binaural rendering neural network

Screening of GJB2.mutations in chinese population

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Journal of Otology 2007年第1期2卷 18-22页

作者： HAN Ming-kun1. HAN Dong-yi1. GUO Yu-fen2. LI Qing-zhong3, ZHAO Ya-li1. 4, RAO Shao-qi1. 5, 6, YUAN Hu1. ZONG Liang1. GUAN Jing2. XU Bai-cheng2. WANG Da-yong1. LAN lan1. WANG Qiu-ju1. 7 1.Department of Otorhinolaryngology/ Head and Neck Surgery, and Institute of Otolaryngology,{1. People Liberation Army General Hospital, {12.,{1. 2.Department of Otorhinolaryngology/ Head and Neck Surgery, the Second Affiliated Hospital of LanZhou University, Lanzhou,{1. 3 Deparment of Otlolaryngology, Eye and ENT Hospital of Fudan University, Shanghai,{1. 4 Department of Biochemistry and Molecular Biology, Institute of Basic Medical sciences, chinese Academy of Medical sciences and Peking Union Medical College, {12.,{1. 5 Departments of Cardiovascular Medicine and Molecular Cardiology, the Cleveland Clinic Foundation, Cleveland, Ohio, USA 6 Department of Bioinformatics, Harbin Medical University, Harbin,{1. 7{1. National Human Genome Center, {12.,{1. Department of Otorhinolaryngology/ Head and Neck Surgery and Institute of Otolaryngology China People Liberation Army General Hospital Beijing China Department of Otorhinolaryngology/ Head and Neck Surgery the Second Affiliated Hospital of LanZhou University Lanzhou China Deparment of Otlolaryngology Eye and ENT Hospital of Fudan University Shanghai China Department of Biochemistry and Molecular Biology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Departments of Cardiovascular Medicine and Molecular Cardiology the Cleveland Clinic Foundation Cleveland Ohio USA Department of Bioinformatics Harbin Medical University Harbin China china National Human Genome Center Beijing China

The GJB2.gene(connexin 2.) has been shown to be responsible for DFNB1.and DFNA3. We screened the GJB2.gene in 488 patients with prelingual deafness(Group 1., 1.4 with postlingual deafness(Group 2., and 1.7 normal hearing subjects(Group 3). We found that, in Group 1. 65 patients(1..32.) were homozygotes or compound heterozygotes and 51.patients (1..45%) carried a single pathogenic mutation. The 2.5delC mutation was the most frequent mutation, accounting for 73.2.% of the known pathogenic alleles in Group 1. No homozygotes or compound heterozygotes were detected in Group 2.or Group 3. Some postlingual deaf patients (2.42.) and normal hearing subjects(4.2.%) were 2.5delC carriers. Our preliminary data indicate that 2.5delC, the most frequent mutation identified in this study, is a major cause for prelingual deafness.

关键词： prelingual deafness postlingual deafness, GJB2 2.5delC chinese

Incident energy dependence of dilepton production in an expanding baryon-rich quark-gluon fireball

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Nuclear Science and Techniques 1998年第1期9卷 5-7页

作者： He Ze jun 1.2., Zhang Jia ju 3, Wang Zi Xing 2.and Liu Bo 4 ( 1.CAST (World Laboratory ), P.O.Box 8730, beijing 1.0080 2.hanghai Institute of Nuclear Research, the {1. Academy of sciences, Shanghai 2.1.00 3Computing

Ｉｎｃｉｄｅｎｔｅｎｅｒｇｙｄｅｐｅｎｄｅｎｃｅｏｆｄｉｌｅｐｔｏｎｐｒｏｄｕｃｔｉｏｎｉｎａｎｅｘｐａｎｄｉｎｇｂａｒｙｏｎ－ｒｉｃｈｑｕａｒｋ－ｇｌｕｏｎｆｉｒｅｂａｌＨｅＺｅＪｕｎ１，２，ＺｈａｎｇＪｉａ... 详细信息

Ｉｎｃｉｄｅｎｔｅｎｅｒｇｙｄｅｐｅｎｄｅｎｃｅｏｆｄｉｌｅｐｔｏｎｐｒｏｄｕｃｔｉｏｎｉｎａｎｅｘｐａｎｄｉｎｇｂａｒｙｏｎ－ｒｉｃｈｑｕａｒｋ－ｇｌｕｏｎｆｉｒｅｂａｌＨｅＺｅＪｕｎ１，２，ＺｈａｎｇＪｉａＪｕ３，ＷａｎｇＺｉＸｉｎｇ２ａ...

关键词：重离子碰撞双轻子产生夸克-胶子火球

Status and circulation characteristics of soil water in dryland field of southeast Shanxi Province

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Journal of Environmental sciences 1998年第4期10卷 27-34页

作者： Zhong Zhao zhan, Zhao ju bao, Mei Xu rong Institute of Agrometeorology, {1. Academy of Agricultural {2., beijing 1.0081. china

Based on the observed soil water data from experimental site located in southeast of Shanxi Province, the physical characteristics of soil water, crop effect on soil moisture, and the field water circulation pattern were studied by using the water balance method. The results suggested that soil water deficit often exists in fields of these areas. From May to june, the amount of water deficit in bare land rises to the maximum (2.2.8 mm) and falls to the minimum (66 6 mm) from August to September. By comparison, because of crop transpiration, both soil water deficit and dry soil layer in cultivated land are 1. 1.40 4 mm more and 2.—70 mm deeper respectively than those of bare land. Crops mainly planted in these areas have a relatively weak utilization ability to soil water. Winter wheat has the highest utilization ability to soil water among the crops planted in these areas. The soil water utilization ability of winter wheat is 2. 2.—30 6% and winter wheat can use soil water that lies in soil layer below a depth of over 2.0 cm. Spring corn and millet can only consume soil water with the maximum ability of 1. 4% and the deepest layer of 0—50 cm or 0—1.0cm, which shows that the soil water utilization ability of winter wheat is higher than that of spring crops. After crop is ripe, more than 41. of available soil water remains unused in field. So, increasing soil water storage and improving crop utilization ability to soil water by adopting efficient agrotechnique measures are the main ways for improving agricultural productivity in dry farming areas of Northern{1..

关键词： soil water field water deficit crop utilization ability to soil water dry land southeast of Shanxi Province.

Erratum to“Gravity-Dependent Animacy Perception in Zebrafish”

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Research 2024年第3期6卷 799-800页

作者： Xiaohan Ma Xiangyong Yuan Jiahuan Liu Li Shen yiwen Yu Wen Zhou Zuxiang Liu Yi Jiang State Key Laboratory of Brain and Cognitive Science CAS Center for Excellence in Brain Science and Intelligence TechnologyInstitute of PsychologyChinese Academy of SciencesBeijing 100101China University of chinese Academy of {1. Beijing 100049China chinese Institute for Brain Research Beijing 102206China State Key Laboratory of Brain and Cognitive Science Institute of BiophysicsChinese Academy of SciencesBeijing 100101China Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefei 230088China

In the Research Article“Gravity-Dependent Animacy Perception in Zebrafish”[1.,there was an error when calculating the velocity and acceleration of the human and pigeon BM stimuli provided by other researchers in ***... 详细信息

关键词： acceleration finding Zebrafish

化学非平衡夸克-胶子物质中等质量双轻子的产生

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物理学报 2003年第11期52卷 2831-2835页

作者：贺泽君龙家丽马国亮马余刚张家驹刘波中国科学院上海原子核研究所中国科学院高能物理研究所北京100039

研究了正在进行化学平衡的富重子夸克胶子物质的双轻子产生 ,发现由于产生在RHIC能量的化学非平衡的富重子夸克胶子物质冷却慢和高的初始温度 ,导致中等质量双轻子产生重大增强 .因此 ,中等质量双轻子的增强可以是夸克胶子物质形... 详细信息

研究了正在进行化学平衡的富重子夸克胶子物质的双轻子产生 ,发现由于产生在RHIC能量的化学非平衡的富重子夸克胶子物质冷却慢和高的初始温度 ,导致中等质量双轻子产生重大增强 .因此 ,中等质量双轻子的增强可以是夸克胶子物质形成的信号 .同时 ,这个增强能补偿由于初始夸克化学势增加引起的双轻子抑制 ,因而双轻子产额的抑制不再是夸克胶子物质产生的信号 .

关键词：化学非平衡夸克-胶子物质双轻子热粲夸克夸克化学势夸克碰撞热力学平衡

Slow recovery from excitation of thalamic reticular nucleus neurons

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Slow recovery from excitation of thalamic reticular nucleus ...

中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Xiong-Jie YU~1.Shi-Gang HE~1.{2.-Fang HE~(1.2. 1.Institute of Biophysics,{1. Academy of {1.,beijing 1.01.1.china 2.Depatment of Rehabilitation {1.,The Hong Kong Polytechnic University,Hong Kong

＜正＞Objective To investigate the temporal response property of the thalamic reticular nucleus（TRN）.Methods Extracelluary recording was made in the TRN auditory sector and medial geniculate body（MGB） while the noise burst was presented to the rat with interstimuli interval（ISI） from 2.0 ms to *** The neuronal responses to the repeated auditory stimuli and electrical stimulation were examined on 95 neurons in the auditory sector of the thalamic reticular nucleus and 2.0}medial geniculate neurons from anesthetized *** TRN neurons showed strong response to the first trial and weak response to *** trials of the repeated auditory stimuli,when the inter-stimulus interval was short （＜3 s）.They responded in the second trial with a firing and sustaining of oscillation similar to that in the first trial,when the ISI was increased to 7 s or even *** was of a great contrast to the MGB neurons,which responded similarly to the repeated auditory stimuli of different *** TRN neurons showed a statistically significant increase in the onset auditory response from 2. Hz to 72.Hz when the ISI was increased from 2.0 ms to 1. s（P ＜ 0.001.ANOVA）.The TRN neurons responded to repeated electrical stimulation of MGB and auditory cortex similarly to the repeated auditory *** stimuli evoked oscillatory firing activities in the TRN *** sustaining of the oscillation was longer when the ISI was *** sustaining of the oscillation was correlated with the latency of the second cluster of spikes,implying that the oscillation consisted of LTS *** The slow recovery of the TRN neurons after oscillation of burst firings to fast repetitive stimulus was a reflection of a different role than the thalamocortical relay *** that the TRN is involved in the process of attention such as attention shift,the slow recovery of TRN neurons probably limits the frequent change of the attention in a fast rhythm.

关键词： thalamic reticular nucleus oscillation medial geniculate body auditory response electrical stimulation auditory cortex

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cnki会议

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消光比在串扰分析中的影响

中国激光 2003年第5期30卷 413-416页

作者：戴无惧张汉一何永琪清华大学电子工程系北京100084 大唐电信北京100081

导出了单一串扰情况下 ,串扰光和系统光噪声共同存在时 ,接收机输入光信号及其基带输出信号的表达式。阐述了信号光与串扰光的物理相干性与信号数字逻辑相关性问题。计算了在最优判决门限情况下 ,背景误码率在1. - 9条件时 ,信号光消光... 详细信息

导出了单一串扰情况下 ,串扰光和系统光噪声共同存在时 ,接收机输入光信号及其基带输出信号的表达式。阐述了信号光与串扰光的物理相干性与信号数字逻辑相关性问题。计算了在最优判决门限情况下 ,背景误码率在1. - 9条件时 ,信号光消光比与串扰光消光比对系统误码率的影响。结果表明 ,消光比在 8～ 1.dB的范围内 ,系统的误码特性接近最优。

关键词：光纤通信技术串扰消光比密集波分复用光噪声相干相关