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内蒙古砒砂岩地区风蚀、水蚀及重力侵蚀交互作用研究

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水土保持学报 2001年第2期15卷 25-29页

作者：唐政洪蔡强国李忠武赵怀玉中国科学院地理科学与资源研究所北京100101 内蒙古自治区伊克昭盟水保所

内蒙古砒砂岩地区是黄河重要的粗沙来源区 ,具有水蚀、风蚀及重力侵蚀交互的特点。利用 3个试验流域1.83～ 1.97年的天然观测资料 ,分析得到了砒砂岩侵蚀交互作用的时空分布规律 ;通过对砒砂岩的理化性质及侵蚀产沙特性的分析表明 ,砒... 详细信息

内蒙古砒砂岩地区是黄河重要的粗沙来源区 ,具有水蚀、风蚀及重力侵蚀交互的特点。利用 3个试验流域1.83～ 1.97年的天然观测资料 ,分析得到了砒砂岩侵蚀交互作用的时空分布规律 ;通过对砒砂岩的理化性质及侵蚀产沙特性的分析表明 ,砒砂岩的产流和产沙能力均高于当地的黄土和风沙土。建立了砒砂岩地区的水蚀模型。

关键词：吡砂岩交互作用风蚀水蚀重力侵蚀土壤侵蚀

Effect of hydroxyurea and etoposide on transduction of human bone marrow mesenchymal stem and progenitor cell by adeno-associated virus vectors

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Acta Pharmacologica Sinica 2004年第2期25卷 70-76页

作者： Xiao-dong ju, Si-quan LOU2. Wei-guo WANG, Jian-qiang PENG3, Hua TIAN Department of Orthopaedics, Peking University Third Hospital, {1. 1.0083 3Institute of Virology, {1. Academy of Preventive Medicine, {1. 1.02.2. china Department of Orthopaedics Peking University Third Hospital 北京 100083 Institute of Virology Chinese Academy of Preventive Medicine 北京 100262

AIM: To study the effect of hydroxyurea and etoposide on transduction of human marrow mesenchymal and progenitor stem cells by adeno-associated virus (AAV). METHODS: Isolated human bone marrow mesenchymal stem and progenitor cells (hMSCs) were cultured in DMEM containing 1. % FBS or 5 % FBS and dexamethasone 1.μmol/L respectively. After being treated with hydroxyurea and etoposide, hMSCs were transduced by AAV-LUC. After two days luciferase activity (relative light unites per second or RLU/s) were tested, which indirectly reflected the relative transduction efficiency of different groups, and virus DNA was isolated by Hirt extraction for Southern hybridization. RESULTS: Transduction luciferase activity and transduction efficiency in cultures treated with hydroxyurea and etoposide were significantly higher than that in control cultures. Dividing cells had about 2.-fold higher transduction efficiencycompared with control cells. Transduction efficiency in stationary cells was about 50 times higher than that in control cells. Southern analysis showed that hydroxyurea and etoposide enhanced second-strand DNA synthesis by rAAV. CONCLUSION: Hydroxyurea and etoposide could increase transduction efficiency of hMSCs by AAV vectors, and stationary cells were more sensitive to these drugs than dividing cells.

关键词： simian adenoviruses hydroxyurea etoposide mesoderm stem cells gene transfer techniques

基于三维运动捕捉技术的踩跷法运动学参数特征研究

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北京中医药大学学报 2018年第3期41卷 235-241页

作者：刘元华冯跃李庆兵万义文罗才贵罗建成都中医药大学四川610075 成都中医药大学附属医院

目的研究踩跷法运动学整体特征及局部特征,为名老专家特色手法提供数据参考。方法应用三维运动捕捉技术记录罗才贵教授及初学者各3个完整踩跷动作,高速摄像头记录操作者下肢髋、膝、踝关节的活动,比较角度、角速度、重心速度在完整周期... 详细信息

目的研究踩跷法运动学整体特征及局部特征,为名老专家特色手法提供数据参考。方法应用三维运动捕捉技术记录罗才贵教授及初学者各3个完整踩跷动作,高速摄像头记录操作者下肢髋、膝、踝关节的活动,比较角度、角速度、重心速度在完整周期及重要时间点的动态变化,分析罗氏踩跷法整体及局部运动学特征。结果与初学者相比,罗教授踩跷动作的整体特征显示髋关节、踝关节角度差异有统计学意义(P1.。局部特征方面显示,在重心下降最低点时刻,周期1.膝关节角速度较小(P1.。在重心上升膝关节打直时刻,周期1.膝关节、踝关节角速度较小及重心速度偏小(P1.;周期2.髋关节角速度、膝关节角速度较小(P1.膝关节角度偏大、角速度较小(P1.,重心速度较小(P2.重心速度偏小(P1.。结论罗氏动作切换过程及施力时关节角度及角速度均较小。说明罗氏踩跷整体稳定、柔和均匀之余,又注重局部"巧劲""寸劲"发力,体现了动静结合、刚柔并济的特点。

关键词：踩跷运动捕捉生物力学运动学

Association of Human Whole-blood NAD+Levels with Nabothian Cyst

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Biomedical and Environmental sciences 2024年第5期37卷 471-478页

作者： XU Ling WANG Yue Xuan WANG Wei FAN Xue CHEN Xue Yu ZHOU Tian Yun LIU Yu He YU Ye YANG Fan ju Zhen Yu ZHOU Yong WANG Deng Liang Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China NHC Key Lab of Reproduction Regulation Shanghai Engineering Research Center of Reproductive Health Drugs and DevicesShanghai Institute for Biomedical and Pharmaceutical TechnologiesShanghai 200237China Department of Applied Statistics Johannes Kepler University LinzLinz 4040Austria Hematology Center Beijing Key Laboratory of Pediatric Hematology OncologyNational Key Discipline of Pediatrics(Capital Medical University)Key Laboratory of Major Diseases in ChildrenMinistry of EducationBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Biostatistics School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Clinical Medicine School of Basic MedicineShanghai Medical College Fudan UniversityShanghai 200032China Department of Biochemistry and Molecular Biology Hengyang Medical SchoolUniversity of South ChinaHengyang 421001HunanChina Administrative Office Total Quality Management OfficeTotal Quality Management InstituteShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China The First Affiliated Hospital of Jinan University Institute of Aging and Regenerative MedicineJinan UniversityJinan 510632GuangzhouChina Department of Scientific Research The First Affiliated Hospital of Huzhou UniversityHuzhou 313000ZhejiangChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated HospitalFujian Medical UniversityFuzhou 350209FujianChina Fujian Provincial Institutes of Brain Disorders and Brain sciences The First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Fujian Provincial Clinical Research Center for Neurological

Objective Little is known about the association between whole-blood nicotinamide adenine dinucleotide(NAD^(+))levels and nabothian *** study aimed to assess the association between NAD^(+)levels and nabothian cysts in healthy chinese *** Multivariate logistic regression analysis was performed to analyze the association between NAD^(+)levels and nabothian *** The mean age was 43.0±1..5 years,and the mean level of NAD^(+)was 31.3±5.3μmol/*** cysts occurred in 1.4(2..7%)participants,with single and multiple cysts in 1.0(1..0%)and84(1..6%)participants,*** total nabothian cyst prevalence gradually decreased from37.4%to 2.1}6%from Q1.to Q4 of NAD^(+)and the prevalence of single and multiple nabothian cysts also decreased across the NAD^(+)*** compared with the highest NAD^(+)quartile(≥34.4μmol/L),the ad{1.sted odds ratios with 95%confidence interval of the NAD^(+)Q1.was 1.89(1.1.–3.1.)for total nabothian *** risk of total and single nabothian cysts linearly decreased with increasing NAD^(+)levels,while the risk of multiple nabothian cysts decreased more rapidly at NAD^(+)levels of 2..0 to35.0μmol/***:Low NAD^(+)levels were associated with an increased risk of total and multiple nabothian cysts.

关键词： Nicotinamide adenine dinucleotide Nabothian cyst Female Risk factor

Comparison of coalbed gas generation between Huaibei-Huainan coalfields and Qinshui coal basin based on the tectono-thermal modeling

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Science china Earth {1. 2011年第7期54卷 1069-1077页

作者： WU YuDong ju {1. HOU QuanLin HU ShengBiao PAN JieNan FAN junJia College of Earth Science Graduate University of the Chinese Academy of Sciences Beijing 100049 China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China Institute of Resources & Environment Henan Polytechnic University Henan 454000 China

The geothermal history and the tectonic subsidence history of the Huaibei-Huainan coalfields were reconstructed by using the vitrinite reflectance data, and their correlative restriction on coalbed gas generation of Huaibei-Huainan coalfields and Qinshui coal basin was discussed. The burial, thermal, and maturity histories of are similar between Huaibei coalfield and Huainan coalfield, obviously different from those of Qinshui coal basin. Based on the tectono-thermal evolution characters of Huaibei-Huainan coalfields and Qinshui basin, the process of coalbed gas generation can be divided into three stages：（1. Dur- ing Early Mesozoic, both in Huaibei-Huainan and Qinshui, the buried depth of Permian coal seams increased rapidly, which resulted in strong metamorphism and high burial temperature of coal seams. At this stage, the coal rank was mainly fat coal, and locally reached coking coal. These created an environment favoring the generation of thermogenic gas. （2. From Late ju- rassic to Cretaceous, in the areas of Huaibei-Hualnan, the strata suffered from erosion and the crust became thinning, and the Permian coal-bearing strata were uplifted to surface. At this stage, the thermogenic gas mostly escaped. Conversely, in Qinshui basin, the cover strata of coal seams kept intact during this stage, and the thermogenic gas were mostly preserved. Furthermore, with the interaction of magmatism, the burial temperature of coal seams reached higher peak value, and it was suitable for the secondary generation of thermogenic gas. （3） From Paleogene onward, in area of Huainan-Huaibei, the maturity of coal and burial temperature were propitious to the generation of secondary biogenic gases. However, in Qinshui basin, the maturity of coal went against genesis of second biogenic gas or thermogenic gas. By comparison, Huaibei-Huainan coalfields are dominated by thermogenic gas with a significant biogenic gas and hydrodynamic overprint, whereas Qinshui basin is dominated mainly by t

关键词： HuaiBei coalfield Huainan coalfield Qinshui coal basin tectono-thermal modeling coalbed gas generation

亮通道先验Retinex对低照度图像的光照补偿

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光学精密工程 2018年第5期26卷 1191-1200页

作者：李赓飞李桂菊韩广良刘培勋江山中国科学院长春光学精密机械与物理研究所吉林长春130033 中国科学院大学北京100049

针对光照不足导致图像质量退化的问题,提出了亮通道先验的Retinex算法用来补偿图像的光照强度。该算法假设局部恒常的光照可以初步满足光照均匀并与场景相似,以亮通道运算对光照分量进行粗估计;通常解决局部处理带来的分块效应问题是采... 详细信息

针对光照不足导致图像质量退化的问题,提出了亮通道先验的Retinex算法用来补偿图像的光照强度。该算法假设局部恒常的光照可以初步满足光照均匀并与场景相似,以亮通道运算对光照分量进行粗估计;通常解决局部处理带来的分块效应问题是采用引导滤波方法,但这会使补偿后的图像纹理模糊甚至丢失细节,为此设计了基于图像结构相似性的融合策略。最后使用Retinex理论模型对光照进行补偿。实验结果表明:所提算法简单高效,能够对图像阴影或夜间图像的低照度区域进行快速地光照补偿,在峰值信噪比(PNSR)上较传统算法提高了5dB左右,在结构相似性(SSIM)上比传统算法提高了7%以上。算法在纯软件系统的PC机上处理640×360的彩色视频时能达到6~1.ms/帧,处理32.×2.6的红外视频时达到4~1.ms/帧,可满足工程需要。

关键词： Retinex 亮通道先验光照补偿

Micropylar guidancel (mg1. MG1.is essential for pollen tube

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Micropylar guidancel (mg1) MG1 is essential for pollen tube

MicroRNA miR-2. inhibits erythropoiesis by targeting activin type Ⅰ receptor ALK4

中国植物学会植物细胞生物学2.1.年学术年会

作者： Hong-ju,Li and Wei-Cai,Yang~* The Key Laboratory of Molecular and Developmental Biology,Institute of Genetics and Developmental Biology,{1. Academy of {2.,1.West Beichen Road,Chaoyang District,beijing 1.01.1.china

In flowering plants,precise guidance of the pollen tube through the female reproductive tissues to the embryo sac is critical for sexual *** tube guidance by which pollen tube find the entry to the embryo sac,is a common phenomenon in angiosperms and requires coordinated male-female gametophytic interactions,but the underlying molecular mechanism is poorly understood. The entire process of pollen tube guidance can be divided into two phases:the sporophytic phase and gametophytic phase,and the latter include funicular phase and micropylar *** are multiple guidance cues along the pollen tube pathway,and the pollen tube employs different mechanism to receive and respond to the *** there are evidences that the synergid in ovule emits diffusible attractants,how the pollen tube responds to them is still unknown.

关键词： Arabidopsis MG1 Pollen tube guidance

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MicroRNA miR-24 inhibits erythropoiesis by targeting activin...

Geochemical Characters of Water Coproduced with Coalbed Gas and Shallow Groundwater in Liulin Coalfield of china

中国遗传学会“发育、遗传和疾病”研讨会

作者： Qiang Wang~1.Zheng Huang~2.Huiling Xue~2.Chengcheng Jin~1.Xiu-Li {2.~3 Jing-Dong J.Han~2.Ye-Guang Chen~(1.) 1.State Key Laboratory of Biomembrane and Membrane Biotechnology,Department of Biological {1. and Biotechnology,Tsinghua University,{1. 1.0084,china 2.CAS Key Laboratory of Molecular Developmental Biology and Center for Molecular Systems Biology,Institute of Genetics and Developmental Biology,the chinese Academy of {1.,Beifing 1.01.1. china 3 Department of Pediatrics,Qilu Hospital of Shandong University,Jinan 2.001.,china

MicroRNAs have been suggested to modulate a variety of cellular *** we report that miR-2. regulates erythroid differentiation by influencing the expression of human activin type I receptor ALK4(bALK4).Ectopic expression of miR-2. reduces the mRNA and protein levels of bALK4 by targeting its 3'-untranslated region and interferes with activin-induced Smad2.phosphorylation and reporter ***,miR-2. represses the activin-mediated accumulation of hemoglobin,an erythroid differentiation marker,in erythroleukemic K562.cells and decreases erythroid colony-forming and burst-forming units of CD34+ hematopoietic progenitor ***4 expression is reversely correlated with miR-2. expression during erythroid ***,our findings define a regulation mode of miR-2. on erythropoiesis by impeding ALK4 expression.

关键词： ALK receptor ALK4 MicroRNA miR-2. inhibits erythropoiesis by targeting activin type miR

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Acta Geologica Sinica(English Edition) 2013年第6期87卷 1690-1700页

作者： YANG Mei ju {1. LIU Guijian TONG Li KANG Yu HOU Quanlin College of Resources and Environment University of Chinese Academy Sciences Key Lab of Computational Geodynamics of chinese Academy of {1. College of Earth Science University of Chinese Academy Sciences School of Earth and Space sciences University of Science and Technology of China Research Center for Process Pollution Control National Engineering Laboratory for Hydrometallurgical Cleaner Production Technology Institute of Process EngineeringChinese Academy of Sciences University of chinese Academy {1.

To reveal the geochemical characters of water coproduced with coalbed gas and shallow groundwater,water samples were collected from 1. wells of coalbed methane and 7 wells of shallow *** pH,CODMn,fCO2.total dissolved solids （TDS）,total hardness,and concentrations of metasilicic acid,sodium and kalium,calcium ion,magnesium ion,ammonium iron,bicarbonate ion,carbonate,chloride,sulfate ion,nitrate ion,fluoride,lithium,zinc,nickel,manganese,iron,boron,barium,*** the samples were *** results showed the following：（1. Concentrations of TDS,chloride,fluoride,sodium and kalium,ammonium,iron,and barium in the water coproduced with coalbed gas exceeded the national standards of{2.; however,physical,chemical,and biological properties of shallow groundwater could meet the national standard.（2. The water produced from coalbed contained mainly Na-Cl·HCO3,with average TDS of 4588.5 ppm,whereas shallow groundwater contained a mixture of chemicals including ***-HCO3·SO4 and ***-HCO3·SO4,with average TDS of 663.8 ppm.（3） In general,it was observed that bicarbonate and sodium accumulated in a reducing environment and deeper system,while depletion of hydrogen ions and dissolution of sulfate,calcium,and magnesium occurred in a redox environment and shallow system.（4） Sodium and kalium,ammonium,chloride,and bicarbonate ions were the main ions found in the study area.

关键词： coalbed methane reservoir geochemical evolution main ions produced water shallow groundwater