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Prevalence of parasitemia and associated immunodeficiency among HIV—malaria co—infected adult patients with highly active antiretroviral therapy

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Asian Pacific Journal of Tropical Medicine 2013年第2期6卷 148-152页

作者： caroline Edijana Omoti chiedozie K.Ojide Patrick V.Lofor Emeka eze joy c.eze Department of Haematology and Blood Transfusion University of Benin Teaching HospitalBenin CityNigeria Department of Medical Microbiology University of Benin Teaching HospitalBenin CityNigeria Department of Internal Medicine University of Benin Teaching HospitalBenin CityNigeria

Objective:To investigate the malaria parasitemia,cD4~+ cell counts and some haematological indices among HIV-malaria co-infected adult patients with highly active antiretroviral therapy (HAART).Methods:A total of 342 adult HIV positive subjects were recruited at the consultant outpatient HIV/AIDS *** of Benin Teaching Hospital,Benin city,Nigeria between June 2011 to November *** samples were taken for malaria parasite count,cD4~+ cell count and other haematological ***:Out of the 342 adult HIV positive subjects a total of 254 patients(74.3%) were found to have malaria *** incidence of malaria parasitemia increased with advancing clinical stage of HIV infection and this was statistically significant(P=0.002).There was no statistical significance when gender was compared with the HIV-malaria status(P>0.05).Of the 254 co-infected patients,134(52.8%) had high parasitemia (>1.25×10~9/L).Sixty patients were found to be hyperparasitemic(>2.5 parasites/L).There was a significant association between cD4~+ cell count and having significant parasitemia(Pco-infected patients had cD4~+ cell count≤200/μL,and majority(44.9%) of this population also had significant *** and thrombocytopenia were not significantly associated with HIV-malaria co-infection(P>0.05).conclusions:The prevalence of parasitemia is high among the HIV/AIDS infected patients.

关键词： HIV Malaria HAART cD4~+

Lithium-ion mobility in layered oxides Li_(2)ca_(1.5)Nb_(3)O_(10),Li_(2)ca_(1.5)TaNb_(2)O_(10)and Li_(2)ca_(1.5)Ta_(2)NbO_(10),enhanced by supercell formation

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Journal of Energy chemistry 2021年第9期30卷 75-84页

作者： Selorm joy Fanah Farshid Ramezanipour Department of chemistry University of LouisvilleLouisvilleKY 40292USA

The formation of a supercell and its impact on lithium-ion conductivity have been studied through synthesis of three layered oxides,Li_(2)ca_(1.5)Nb_(3)O_(10),Li_(2)ca_(1.5)TaNb_(2)O_(10)and Li_(2)ca_(1.5)Ta_(2)NbO_(10),related to Ruddlesden-Popper *** diffraction experiments show that these materials feature a supercell,which is significantly larger(√2a×√2b×1c)than that of a typical RuddlesdenPopper *** impedance spectroscopy shows that the formation of the new supercell is associated with enhanced lithium-ion conductivity of these materials as compared with the Sranalogue,Li_(2)Sr_(1.5)Nb_(3)O_(10),which lacks the *** addition,a systematic trend is observed in the ionic conductivity:Li_(2)ca_1.5Ta_(2)NbO10ca_(1.5)TaNb_(2)O_(10)ca_(1.5)Nb_(3)O_(10).The Arrhenius analysis in the temperature range 25–400°c shows that activation energy for the temperature-dependent rise in conductivity follows a similar *** analyses of real and imaginary components of impedance,dielectric properties,tangent loss,and complex modulus show the systematic increase in lithium-ion *** dielectric values mirror the same trend as ionic conductivity,where the most conductive material shows the highest dielectric *** addition,the same trend is observed in the peak and dispersion of dielectric loss and complex modulus as a function of angular frequency,indicating a systematic rise in lithium-ion *** fundamental study is aimed at exploring the impact of structural modifications on ionic conductivity in solids.

关键词： Lithium-ion conductivity Supercell Impedance Dielectric analyses

Lepton and quark mixing patterns with generalized cP transformations

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chinese Physics c 2022年第10期46卷 25-42页

作者： joy Ganguly Raghavendra Srikanth Hundi Department of Physics Indian Institute of Technology HyderabadKandi-502284India

In this study,we modify a scenario,originally proposed by Grimus and Lavoura,in order to obtain maximal values for the atmospheric mixing angle and cP,violating the Dirac phase of the lepton *** achieve this,we employ cP and some discrete symmetries in a type Ⅱ seesaw *** make predictions about the neutrino mass ordering and smallness of the reactor angle,we establish some conditions on the elements of the neutrino mass matrix of our ***,we study the quark masses and mixing pattern within the framework of our model.

关键词： neutrino physics nuetrino mass and mixing model quark mass and mixing analysis of scalar potential

The IUGS commission on Geological Sciences for Environmental Planning （cOGEOENVIRONMENT） completes its term

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Episodes 2005年第1期28卷 64-65页

作者： joy Pereira Institute for Environment and Development LESTARI Universiti Kebangsaan Malaysia

During the last 2 years the IUGS has reviewed its Organisation and Operations to allow more efficient and effective administration into the future. Among the items reviewed was the life of commissions which have now been defined at a maximum of 8 years. As a consequence cOGEOENVIRONMENT, which has been in existence since early 1990, was formally closed down at the IGc in Florence in August 2004. The decision by the IUGS council to close cOGEOENVIRONMENT did not in any way imply that the role of the IUGS in promoting geoscience in environment matters was completed.

关键词：地质学环境规划 IUGS 工作思路发展目标

Heterogeneous molecular catalysts for electrocatalytic cO2 reduction

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Nano Research 2019年第9期12卷 2093-2125页

作者： Nathan corbin joy Zeng Kindle Williams Karthish Manthiram Department of chemical Engineering Massachusetts Institute of TechnologyCambridgeMA 02139USA

This review provides an overview of the literature regarding heterogeneous molecular catalysts for electrochemical cO2 reduction (EcR).Fundamental aspects of the science,including aggregation,electrochemical rate laws,and electrode-catalyst electronic coupling,are discussed to provide a solid foundation on which to design experiments and interpret *** aspects of EcR are presented based on electrokinetic and spectroscopic measurements as well as density functional theory (DFT) *** is improving for electrokinetic measurements,but the redox state of the metal center under reaction conditions and DFT reaction pathways lack agreement in the *** the tunable aspects of the molecular catalyst,the impacts of the metal center,ligand substituents,and electrode support on the activity and selectivity toward EcR are presented with an emphasis on those studies that controlled for aggregation and minimized mass-transport *** three-dimensional (3D) structures such as polymers,metal-organic frameworks (MOFs),and covalent-organic frameworks (cOFs) are discussed as highly tunable architectures that begin to mimic the catalytic pockets of enzyme active *** achieve the full potential of these catalysts,design principles must emerge based on a combination of deconvoluting measurements to extract intrinsic catalyst properties and more reliable theoretical calculations to predict reaction pathways.

关键词： cO2 reduction electrocatalysis porphyrins phthalocyanines molecular complexes heterogeneous catalysis

Macrophage Nrf2,an anti-inflammatory signal in hepatic ischemia/reperfusion injury

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cellular & Molecular Immunology 2023年第5期20卷 427-428页

作者： joy X.Jiang Department of Molecular Biosciences UC DavisRm.30091089 Veterinary Medicine Dr.DavisCA95616US

Recently,the manuscript entitled Macrophage nuclear factor erythroid 2-related factor 2(Nrf2)deficiency promotes innate immune activation by tissue inhibitor of metalloproteinase 3(Timp3)-mediated RhoA/ROcK pathway in the ischemic liver by Rao and colleagues in Hepatology 2022,vol.75[1]described a novel role of Nrf2 in innate immunity in response to hepatic ischemia/reperfusion injury(IRI).Nrf2 is generally considered a redox signaling controller and drives protective signals as an antioxidant gene in multiple organs and diseases.

关键词： Nrf2 hepatic Macrophage

Multi-scale drivers of soil resistance predict vulnerability of seasonally wet meadows to trampling by pack stock animals in the Sierra Nevada,USA

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Ecological Processes 2020年第1期9卷 364-377页

作者： joy S.Baccei Mitchel P.Mcclaran Tim J.Kuhn Stephen c.Hart Environmental Systems Graduate Group University of CaliforniaMercedCA 95343USA Uc Merced Vernal Pools and Grassland Reserve UC Merced Natural Reserve SystemMercedCA 95343USA School of Natural Resources and the Environment University of ArizonaTucsonAZ 85721USA Resources Management and Science Yosemite National ParkEl PortalCA 95318USA Department of Life&Environmental Sciences and Sierra Nevada Research Institute University of CaliforniaMercedCA 95343USA.

Background:Meadow ecosystems have important ecological functions and support socioeconomic services,yet are subject to multiple stressors that can lead to rapid *** the Sierra Nevada of the western USA,recreational pack stock(horses and mules)use in seasonally wet mountain meadows may lead to soil trampling and meadow degradation,especially when soil water content is high and vegetation is ***:In order to improve the ability to predict meadow vulnerability to soil disturbance from pack stock use,we measured soil resistance(SR),which is an index of vulnerability to trampling disturbance,at two spatial scales using a stratified-random sampling *** then compared SR to several soil and vegetation explanatory variables that were also measured at the two spatial scales:plant community type(local scale)and topographic gradient class(meadow scale).Results:We found that local-scale differences in drivers of SR were contingent on the meadow scale,which is important because multiple spatial scale evaluation of ecological metrics provides a broader understanding of the potential controls on ecological processes than assessments conducted at a single spatial *** also found two contrasting explanatory models for drivers of SR at the local scale:(1)soil gravimetric water content effects on soil disaggregation and(2)soil bulk density and root mass influence on soil *** resistance was insufficient to sustain pack stock use without incurring soil deformation in wet plant communities,even when plant cover was maximal during a major ***:Our study provides new information on seasonally wet meadow vulnerability to trampling by pack stock animals using multi-scale drivers of SR,including the contrasting roles of soil disaggregation,friction,and *** work aims to inform meadow management efforts in the Sierra Nevada and herbaceous ecosystems in similar regions that are subject to seasonal soil saturation and livestock u

关键词： Hydrogeomorphic classification Hydrologic regime Pack stock Plant communities Soil properties Soil strength

Uncomfortable prototypes： Rethinking socio-cultural factors for the design of public housing in Billiri, north east Nigeria

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Frontiers of Architectural Research 2013年第3期2卷 310-321页

作者： joy Joshua Maina School of the Built Environment University of Nottingham Nottingharn NG7 2RD UK

Public housing delivery in developing countries often involves the provision of government- funded housing units. Over time, occupants transform such units to suit their changing needs or to increase and improve housing stock-a practice that has been the focus of several documented studies intended to inform policy makers about changing housing trends. Abandoned units have, however, received comparatively less attention. The present paper reports findings from the documentation and analyses of abandoned and modified prototype units in Billiri, the main town occupied by the Tangale community in north east Nigeria. The methodology involves space syntax methods, as well as the analyses of space use patterns in 45 randomly selected compounds built by the community and in two sets of prototype housing units in the study area. Results suggest that socio-cultural factors related to kinship, security, and basic needs, which form part of the community heritage, are inadequately reflected in the location and design of the units, accounting for their abandonment and modification. These findings have implications for future housing policies in the area.

关键词： Public housing Prototype units Socio-cultural factorsTangale land North east Nigeria

Mining diversity of the natural biorefinery housed within Tipula abdominalis larvae for use in an industrial biorefinery for production of lignocellulosic ethanol

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Insect Science 2010年第3期17卷 303-312页

作者： Dana M. cook joy Doran-Peterson Microbiology Department University of Georgia Athens Georgia USA

Although they are the largest taxonomic group of animals, relatively few insects have been examined for symbiotic relationships with micro-organisms. However, this is rapidly changing because of the potential for examination of the natural insectmicrobe-lignocellulose interactions to provide insights for biofuel technology. Micro-organisms associated with lignocellulose-consuming insects often facilitate the digestion of the recalcitrant plant diet; therefore these microbial communities may be mined for novel lignocellulose-degrading microbes, or for robust and inexpensive biocatalysts necessary for economically feasible biofuel production from lignocellulose. These insect-microbe interactions are influenced by the ecosystem and specific lignocellulose diet, and appre- ciating the whole ecosystem-insect-microbiota-lignocellulose as a natural biorefinery provides a rich and diverse framework from which to design novel industrial processes. One such natural biorefinery, the Tipula abdominalis larvae in riparian ecosystems, is reviewed herein with applications for biochemical processes and overcoming challenges involved in conversion of lignocellulosic biomass to fuel ethanol. From the dense and diverse T. abdominalis larval hindgut microbial community, a cellulolytic bacterial isolate, 27c64, demonstrated enzymatic activity toward many model plant polymers and also produced a bacterial antibiotic. 27c64 was co-cultured with yeast in fermentation of pine to ethanol, which allowed for a 20% reduction of commercial enzyme. In this study, a micro-organism from a lignocellulose-consuming insect was successfully applied for improvement of biomass-to-biofuel technology.

关键词： ethanol hydrolytic enzymes insect-associated microorganisms lignocellulose