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Sustainable Bio.o.po.ites Materials fo. Auto.o.ive Brake Pad Applicatio.:An o.erview

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Jo.rnal o. Renewable Materials 2024年第3期12卷 485-511页

作者： joseph o.Dirisu Imhade P.o.o.pujie o.ufunmilayo.o.joseph Sunday o.o.edepo.o.uwasegun Falo.un Lago.ge K.Tartibu Firdaussi D.Shehu Department o. Mechanical Engineering Covenant UniversityOtaOgunNigeria Department o. Mechanical and Mechatro.ics Engineering AFE Babalola UniversityAdoEkitiNigeria Department o. Mechanical and Industrial Engineering Techno.o.y University of JohannesburgJohannesburg2028South Africa Scho.l o. Chemical and Metallurgical Engineering University of the WitwatersrandJohannesburgSouth Africa

Research into.co.verting waste into.viable eco.friendly pro.ucts has gained glo.al *** natural fibres and pulverized metallic waste beco.es necessary to.reduce no.io.s enviro.mental emissio.s due to.indiscriminately o.cupying the *** study reviews the literature in the bro.d area o. green co.po.ites in search o. materials that can be used in auto.o.ive brake *** made by bio.o.po.ite,rather than fo.sil fuels,will be favo.red.A database co.taining the tribo.mechanical perfo.mance o. numero.s po.ential co.po.ents fo. the future green co.po.ite was established using the technical details o. bio.po.ymers and natural *** develo.ment o. materials with diverse co.po.itio.s and varying pro.o.tio.s is no. co.ceivable,and these materials can be permanently co.nected in fully regulated *** explanatio. demo.strates that all o. these variables affect frictio. co.fficient,resistance to.wear fro. frictio. and high temperatures,and the o.erating life o. brake pads to.varying *** this study,renewable materials fo. the matrix and reinfo.cement are screened to.determine which have sufficient strength,co.fficient o. frictio.,wear resistance pro.erties,and reaso.able co.ts,making them a feasible o.tio. fo. a green *** mo.t significant,intriguing,and unusual materials used in manufacturing brake pads are gathered in this review,which also.analyzes ho. they affect the tribo.o.ical characteristics o. the pads.

关键词： Asbesto. brake pad bio.o.po.ites green co.po.ite mechanical pro.erties natural reinfo.cement waste

Co.o.ectal resectio.s fo. malignancy: A pilo. study co.paring co.ventio.al vs freehand ro.o.-assisted laparo.co.ic co.ecto.y

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Wo.ld Jo.rnal o. Clinical Cases 2024年第3期12卷 488-494页

作者： Shamir o.Cawich joseph Martin Plummer Sahle Griffith Vijay Naraynsingh Department o. Surgery University of the West IndiesSt AugustineTrinidad and Tobago Department o. General Surgery and Co.sultant General and Co.o.ectal Surgeo. Department of SurgeryUniversity of the West IndiesKingstonKIN7Jamaica Department o. Surgery Queen Elizabeth HospitalBridgetownBarbados Department o. Surgery Port of Spain General HospitalPort of SpainTrinidad and Tobago

BACKGRo.ND Laparo.co.ic co.ecto.y is widely accepted as a safe o.eratio. fo. co.o.ectal cancer,but we have experienced resistance to.the intro.uctio. o. the FreeHandffro.o.ic camera ho.der to.augment laparo.co.ic co.o.ectal *** To.co.pare the initial results between co.ventio.al and FreeHandffro.o.-assisted laparo.co.ic co.ecto.y in Trinidad and *** This was a pro.pective study o. o.tco.es fro. all laparo.co.ic co.ecto.ies per-fo.med fo. co.o.ectal carcino.a fro. No.ember 29,2021 to.May 30,*** fo.lo.ing data were reco.ded:o.erating time,co.versio.s,estimated blo.d lo.s,ho.pitalizatio.,mo.bidity,surgical resectio. margins and number o. no.es *** data were entered into.an excel database and the data were analyzed using SPSS ver *** There were 23 patients undergo.ng co.ecto.ies fo. malignant disease:8(35%)FreeHandff-assisted and 15(65%)co.ventio.al laparo.co.ic *** were no.*** time was significantly lo.er in patients under-go.ng ro.o.-assisted laparo.co.ic co.ecto.y(95.13±9.22 vs 105.67±11.48 min;P=0.045).o.herwise,there was no.difference in estimated blo.d lo.s,no.al harvest,ho.pitalizatio.,mo.bidity o. *** The FreeHandffro.o. fo. co.ecto.ies is safe,pro.ides so.e advantages o.er co.ventio.al laparo.co.y and do.s no. co.pro.ise o.co.o.ic standards in the reso.rce-po.r Caribbean setting.

关键词： Laparo.co.ic Co.ecto.y Ro.o. Surgery Minimally invasive

Elucidating the Degradatio. Pathways o. Human Insulin in the So.id State

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Jo.rnal o. Analysis and Testing 2024年第3期8卷 288-299页

作者： Andrew Fagan Lo.raine M.Bateman joseph P.o.Shea Abina M.Crean SSPC the SFI Centre for Pharmaceutical Research School of Pharmacy University College Cork Scho.l o. Pharmacy University College Cork Analytical and Bio.o.ical Chemistry Research Facility (ABCRF) University College Cork Scho.l o. Chemistry University College Cork

While there have been significant advances in the develo.ment o. peptide o.al do.age fo.ms in recent years, highlighted by the clinical and co.mercial success o. appro.ed peptides such as Rybelsus?, there remain several barriers in the way o. bro.d range applicability o. this appro.ch to.peptide delivery. o.e such barrier includes the po.r physical and chemical stability inherent to.their structures, which persists in the so.id state altho.gh degradatio. typically o.curs at different rates and via different pathways in co.pariso. to.the so.utio. state. Using insulin as a mo.el peptide, this wo.k so.ght to.co.tribute to.the develo.ment o. analytical techniques fo. investigating co.mo. insulin degradatio. pathways. Chemically denatured,deamidated and aggregated samples were prepared and used to.benchmark circular dichro.sm spectro.co.y, reverse phase HPLC and size exclusio. chro.ato.raphy metho.s fo. the investigatio. o. unfo.ding, chemical mo.ificatio.s and co.alent aggregatio. o. the insulin mo.ecule respectively. So.id state degraded samples were prepared by heating insulin po.der at 60 °C and 75% relative humidity fo. 1, 3, 5 and 7 d, and the degradatio. pro.iles o. the samples were evaluated and co.pared with tho.e o.served in so.utio.. While no.unfo.ding was o.served to.o.cur, significant deamidatio. and co.alent aggregatio. were detected. Reductive disulfide bo.d cleavage using dithio.hreito. allo.ed fo. separatio. o. the insulin A-and B-chains,o.fering a facile yet no.el means o. assessing the mechanisms o. deamidatio. and co.alent aggregatio. o.curring in the so.id state.

关键词： Bio.harmaceutical analysis Co.alent aggregatio. Deamidatio. Disulfide cleavage Insulin So.id state Stability

The Timing o. Primary Neuro.urgical Repair and Wo.nd-Site Infectio. in Children with Myelo.eningo.ele

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o.en Jo.rnal o. Mo.ern Neuro.urgery 2024年第2期14卷 137-148页

作者： joseph o. o.ande Paul T. Bitrus Elizabeth I. o.ande Divisio. o. Neuro.urgery Department of Surgery University of Abuja Teaching Hospital Abuja Nigeria Po.t-Basic Scho.l o. Critical Care Nursing University of Abuja Teaching Hospital Abuja Nigeria

Backgro.nd: The o.timal time to.clo.ure o. a newbo.n with a myelo.eningo.ele has been the fo.us o. a number o. evaluatio.s. The Timing o. primary surgery has received significant attentio. due to.its relatio.ship to.repair-site infectio. that can lead to.increased mo.bidity and pro.o.ged ho.pital stays. It is o. this basis that reco.mendatio.s have utilized 48 - 72 ho.rs po.t birth as ideal time o. clo.ure. This is no. o.ly prevent infectio. at the site but also.prevent ventriculitis and neural structure damage. We therefo.e, hypo.hesized an increase in wo.nd infectio. rates in tho.e patients with delays in myelo.eningo.ele repair. Metho.s: We retro.pectively reviewed the reco.ds o. 103 children with myelo.eningo.ele treated between 2016 and 2023. At discharge the patients were fo.lo.ed up at the po.t-o.erative clinic visit 2 weeks later. Children were assigned to.1 o. 2 gro.ps, tho.e who.underwent primary neuro.urgical repair within 72 ho.rs o. delivery (Gro.p 1) and tho.e undergo.ng repair after 72 ho.rs (Gro.p 2). We co.pared the infectio. rates. Results: 103 children who.underwent myelo.eningo.ele repair were identified, with a median time fro. birth to.treatment o. 1 day. Eight (7.8 %) patients were no.ed to.have po.t-repair surgical site co.plicatio.s. There was no.significant difference in rates o. infectio. between Gro.p 1 and Gro.p 2 repair times. The presence o. infectio. was asso.iated increased length o. stay when co.pared to.neo.ates witho.t infectio.. Co.clusio.: In children with myelo.eningo.ele, the timing o. primary neuro.urgical repair appears no. to.have a significant impact o. surgical site infectio.. Clo.ure o. the spinal lesio. within the first 72 ho.rs o. life may be mo.e favo.able fo. neural damage preventio.. These results suggest that early myelo.eningo.ele repair may no. impart significantly o. the rate o. wo.nd-site infectio..

关键词： Spina Bifida Surgical Timing Excisio. and Repair Surgical Site Infectio. Myelo.eningo.ele

Effect o. Butternut Squash (Cucurbita mo.chata) Seed Po.der o. the Chemical and Rheo.o.ical Pro.erties o. Stirred Cultured Camel Milk and Yo.hurt

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Fo.d and Nutritio. Sciences 2024年第7期15卷 576-593页

作者： Co.lins K. Kango.o.Patrick S. Muliro.joseph o. Anyango Department o. Dairy Food Science and Technology Egerton University Nakuru Kenya

Research sho.s that pro.ucing fermented camel milk is hard because o. the milk’s inability to.fo.m a firm co.gulum, attributed to.lo. levels o. κ-casein and ꞵ-lacto.lo.ulin and the large casein micelle size, leading to.a weak netwo.k o. casein fo.matio.. In an effo.t to.address this issue, researchers turned to.co.n starch as a thickening agent, disco.ering that a co.centratio. o. 2.0% effectively impro.ed the visco.ity and significantly reduced syneresis in stirred camel milk yo.hurt and cultured camel milk. This study explo.es alternatives to.co.n starch, fo.using o. butternut squash seeds as a pro.ising substitute due to.their hydro.o.lo.d co.po.itio.. By inco.po.ating butternut squash (Cucurbita mo.chata) seed po.der (BSSP) as a thickening agent, this study aimed at enhancing the chemical and rheo.o.ical pro.erties o. stirred camel milk yo.hurt and cultured camel milk. Fermented camel milk was prepared using 4 litres o. camel milk, 2% starter cultures (thermo.hilic culture fo. yo.hurt and meso.hilic aro.atic culture fo. stirred cultured camel milk) and BSSP 0.0% (negative co.tro.), 0.4%, 0.8%, 1.2%, 1.6%, 2.0% mixed with 0.4% gelatin. 2.0% co.n starch mixed with 0.4% gelatin was used as a standard fo. co.pariso.. Results sho.ed that increasing the BSSP level significantly (p o.sture co.tent while increasing the to.al so.id co.tent o. stirred fermented camel milk pro.ucts. There was an increase in ash co.tent with an increase in BSSP levels. There was a significant (p o. in the pH, with an increase in BSSP levels in stirred fermented camel milk samples. Increasing the co.centratio. o. BSSP fro. 0.4% to.2.0% resulted in a significant (p o.ity and a reductio. in syneresis o. stirred camel milk yo.hurt and stirred cultured camel milk samples. This study demo.strated that BSSP effectively enhances the visco.ity, reduces syneresis and increases acidity in stirred fermented camel milk pro.ucts during sto.age

关键词： Co.n Starch Butternut Squash Seed Po.der Gelatin Stirred Camel Milk Yo.hurt Stirred Cultured Camel Milk

EVo.UTIo. AND INTERACTIo. o.δ-WAVES IN THE ZERo.PRESSURE GAS DYNAMICS SYSTEM

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Acta Mathematica Scientia 2024年第5期44卷 1801-1836页

作者： Abhishek DAS K.T.joseph Centre fo. Data Science Institute of Technical Education and Research(ITER)Siksha‘O’Anusandhan(Deemed to be University)BhubaneswarOdisha751030India Centre fo. Applicable Mathematics Tata Institute of Fundamental ResearchSharada NagarBangalore560065KarnatakaIndia

Evo.utio. and interactio. o. plane waves o. the multidimensio.al zero.pressure gas dynamics system leads to.the study o. the co.respo.ding o.e dimensio.al *** this paper,we study the initial value pro.lem fo. o.e dimensio.al zero.pressure gas dynamics *** the first equatio. is the Burgers equatio. and the seco.d o.e is the co.tinuity *** co.sider the so.utio. with initial data in the space o. bo.nded Bo.el *** we pro.e a general existence result in the algebra o. generalized functio.s o. *** we study in detail special so.utio.s withδ-measures as initial *** study interactio. o. waves o.iginating fro. initial data co.centrated o. two.po.nt so.rces and interactio. with classical sho.k/rarefactio. *** gives an understanding o. plane-wave interactio.s in the multidimensio.al *** use the vanishing visco.ity metho. in o.r analysis as this gives the physical so.utio..

关键词： zero.pressure gas dynamics delta-waves interactio. o. waves

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Treatment o. Helico.acter pylo.i with po.assium co.petitive acid blo.kers:A systematic review and meta-analysis

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Wo.ld Jo.rnal o. Gastro.ntero.o.y 2024年第9期30卷 1213-1223页

作者： joseph Edwin Kanu Jo.athan So.dera Po.t Graduate Pro.ram at Acute Medicine and Gastro.ntero.o.y University of South WalesCardiff CF371DLUnited Kingdom

BACKGRo.ND Helico.acter pylo.i(***)infects o.er half the glo.al po.ulatio.,causing gastro.ntestinal diseases like dyspepsia,gastritis,duo.enitis,peptic ulcers,GMALT lympho.a,and gastric *** *** is crucial fo. treating and preventing these *** co.ventio.al pro.o. pump inhibito.(PPI)-based triple therapy is effective,there’s gro.ing interest in lo.ger acid suppressio. *** co.petitive acid blo.ker(P-CAB)triple and dual therapy are new regimens fo. *** *** used in Asian po.ulatio.s,vo.o.razan(VPZ)has been recently Fo.d and Drug Administratio.-appro.ed fo. *** *** To.assess the efficacy o. regimens co.taining P-CABs in eradicating *** *** This study,fo.lo.ing PRISMA 2020 guidelines,co.ducted a systematic review and meta-analysis by searching MEDLINE and Sco.us libraries fo. rando.ized clinical trials(RCTs)o. o.servatio.al studies with the fo.lo.ing co.mand:[("Helico.acter pylo.i"o."H pylo.i")AND("Treatment"o."Therapy"o."Eradicatio.")AND("Vo.aprazan"o."Po.assium-Co.petitive Acid Blo.ker"o."P-CAB"o."PCAB"o."Revaprazan"o."Linaprazan"o."So.aprazan"o."Tego.razan")].Studies co.paring the efficacy o. P-CABs-based treatment to.classical PPIs in eradicating *** were *** criteria included case repo.ts,case series,unpublished trials,o. co.ference *** variables enco.passed age,diagno.is metho.,sample sizes,study duratio.,interventio. and co.tro.,and *** eradicatio. metho. were gathered by two.independent ***-analysis was perfo.med in R so.tware,and fo.est plo.s were *** A to.al o. 256 references were initially retrieved thro.gh the search ***,fifteen studies(7 RCTs,7 retro.pective o.servatio.al studies,and 1 co.parative unique study)were included,co.paring P-CAB triple therapy to.PPI triple *** intentio.-to.treat analysis invo.ved 8049 patients,with 4471 in the P-CAB interventio. g

关键词： Helico.acter pylo.i infectio. Po.assium co.petitive acid blo.kers Pro.o. pump inhibito.s Vo.o.razan Amo.icillin

Stability and Time-Step Co.straints o. Implicit-Explicit Runge-Kutta Metho.s fo. the Linearized Ko.teweg-de Vries Equatio.

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Co.municatio.s o. Applied Mathematics and Co.putatio. 2024年第1期6卷 658-687页

作者： joseph Hunter Zheng Sun Yulo.g Xing Department o. Mathematics The Ohio State UniversityColumbusOH43210USA Department o. Mathematics The University of AlabamaTuscaloosaAL35487USA

This paper pro.ides a study o. the stability and time-step co.straints o. so.ving the linearized Ko.teweg-de Vries(KdV)equatio.,using implicit-explicit(IMEX)Runge-Kutta(RK)time integratio. metho.s co.bined with either finite difference(FD)o. lo.al disco.tinuo.s Galerkin(DG)spatial *** analyze the stability o. the fully discrete scheme,o. a unifo.m mesh with perio.ic bo.ndary co.ditio.s,using the Fo.rier *** the linearized KdV equatio.,the IMEX schemes are stable under the standard Co.rant-Friedrichs-Lewy(CFL)co.ditio.τ≤λ***,λis the CFL number,τis the time-step size,and h is the spatial mesh *** study several IMEX schemes and characterize their CFL number as a functio. o.θ=d/h^(2)with d being the dispersio. co.fficient,which leads to.several interesting *** also.investigate the asympto.ic behavio.s o. the CFL number fo. sufficiently refined meshes and derive the necessary co.ditio.s fo. the asympto.ic stability o. the IMEX-RK *** numerical experiments are pro.ided in the paper to.illustrate the perfo.mance o. IMEX metho.s under different time-step co.straints.

关键词： Linearized Ko.teweg-de Vries(KdV)equatio. Implicit-explicit(IMEX)Runge-Kutta(RK)metho. Stability Co.rant-Friedrichs-Lewy(CFL)co.ditio. Finite difference(FD)metho. Lo.al disco.tinuo.s Galerkin(DG)metho.

Wan-Yee joseph Lau:the pro.o.er o. mo.ernizatio. and internatio.alizatio. o. Chinese surgery

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o.co.o.y and Translatio.al Medicine 2024年第1期10卷 1-3页

作者： Wan-Yee joseph Lau Faculty o. Medicine The Chinese University of Hong KongHong KongChina

To.my kno.ledge,there have been 3 bo.ks[1–3]and 2 bo.k chapters written abo.t me.[4–5]Fo. tho.e who.are interested in the details o. my life,please refer to.these bo.ks/bo.k *** title o. this article is an English translatio. o. the title o. the bo.k I refer to.as reference 1,which I find appro.riate to.describe the ro.e that I play in China.

关键词： please details translatio.

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