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Epidemiological and Clinical Aspects of Hospitalized Patients with Chronic Rheumatic Disease at Cocody University Hospital in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2023年第3期13卷 65-70页

作者： Ehaulier Soh Christian Louis Kouakou Charles Sougué Konan Joe Clauvis Yao Aissata Traore joseph kan enock koffi Jean Jacques Goua Francine Same Bebey Phillipe Goupille Jean Claude Felix Daboiko Rheumatology Department Bouake University Hospital Bouake C&#244te d’Ivoire Rheumatology Department Cocody University Hospital Abidjan C&#244te d’Ivoire Department of Internal Medicine Sour&#244 Sanou University Hospital Bobo Dioulasso Burkina Faso Rheumatology Department Laquintinie Hospital Douala Cameroon Rheumatology Department Tours University Hospital Tours France

Objective: To study the epidemiological and diagnostic features of chronic rheumatic disease (CRD) in a black population in sub-Saharan Africa. Patients and Methods: Retrospective descriptive study over eight years (January 2005 to December 2012) of patients seen for CRD in rheumatology hospitalization at the CHU de Cocody in Abidjan, Côte d’Ivoire. Results: Of 3147 hospitalized patients, 92 had CRD, a frequency of 2.9%. The mean age of patients was 43.50 ± 15.6 years (extremes: 10 to 79 years). The sex ratio was 0.08 (7 men and 85 women). The socio-economic level was low in 44 patients (47.8%), medium in 44 patients (47.8%), and high in 4 patients (4.4%). The reasons for consultation were polyarthritis (64.1%), polyarthralgia (30.4%), and oligoarthritis (5.4%). The mean duration of symptomatology was 19 months (range: 3 to 20 years). The mean length of hospital stay was 14.2 ± 7.7 days (range: 2 to 36 days). The CRD observed were: rheumatoid arthritis (59.8%), systemic lupus erythematosus (23.9%), mixed connective tissue disease (6.5%), undifferentiated connective tissue disease (3.3%), polymyositis (3.3%), systemic scleroderma (2.2%), and systemic vasculitis (1%). Conclusion: CRD is not uncommon in rheumatology hospitals in Abidjan. Diagnostic delays are long, and rheumatoid arthritis and systemic lupus erythematosus are the most frequently encountered conditions.

关键词： Chronic Rheumatic Disease Rheumatoid Arthritis Lupus Abidjan

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Magma Mixing Genesis of the Mafic Enclaves and Related Granitoids in the kan Granite-Gneiss Complex of Central Côte d’Ivoire: Evidence from Geology, Petrology and Geochemistry

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Open Journal of Geology 2024年第8期14卷 760-786页

作者： koffi Raoul Teha koffi Kossonou Jean-Marie Pria koffi joseph Brou Alain Nicaise Kouamelan Marc Ephrem Allialy Souad M’Rabet Mineral and Energy Resources Laboratory (LGRME) Flix Houphout-Boigny University Abidjan Ivory Coast Environmental Sciences and Technology Laboratory Department of Earth Sciences Jean Lorougnon-Guede Daloa University Daloa Ivory Coast Laboratory of Geosciences and Environment Department of Geology Ibn Tofal University of Knitra Knitra Morocco

The mafic enclaves from Paleoproterozoic domain are considered to be the results of large-scale crust-mantle interaction and magma mixing. In this paper, petrography, mineralogy and geochemistry were jointly used to determine the origin of the mafic enclaves and their relationship with the host granitoids of the kan granite-gneiss complex. This study also provides new information on crust-mantle interactions. The mafic enclaves of the kan vary in shape and size and have intermediate chemical compositions. The diagrams used show a number of similarities in the major elements (and often in the trace elements) between the mafic enclaves and the host granitoids. Geochemical show that the kan rock are metaluminous, enriched in silica, medium to high-K calc-alkaline I-type granite. The similarities reflect a mixing of basic and acid magma. Mafic enclaves have a typical magmatic structure, which is characterized by magma mixing. The genesis of these rocks is associated with the context of subduction. They result from the mixing of a mafic magma originating from the mantle and linked to subduction, and a granitic magma (type I granite) that arises from the partial melting of the crust.

关键词： Magma Mixing Mafic Microgranular Enclaves Host Granitoids kan Granite-Gneiss Complex West Africa

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Epidemiological, Clinical and Paraclinical Profile of Osteoarthritis of the Lower Limbs in Obese Patients at the Cocody University Teaching Hospital

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Open Journal of Rheumatology and Autoimmune Diseases 2024年第2期14卷 69-76页

作者： Nzima Brice Kollo Aboubakar Bamba¹ Aboubacar Sidiki Condé Nzima Hilary Ngon kanbaye Medom Ada Nina Kpami Yaya Coulibaly kan joseph Enoch koffi Ehaulier Soh Christian Louis Kouakou Mohamed Diomandé¹ Edmond Eti Rheumatology Department Cocody University Hospital Abidjan C&#244te d&#8217Ivoire Internal Medicine Department Yaounde University Hospital Yaounde Cameroon Rheumatology Department Bouake University Hospital Bouake C&#244te d&#8217Ivoire

Objective: To describe the epidemiological, clinical and paraclinical characteristics of osteoarthritis of the lower limbs in obese patients at the Cocody University Teaching Hospital. Methodology: This was an analytical cross-sectional study carried out in the rheumatology department of the Cocody UTH in Abidjan (Ivory Coast) from March 1 to April 30 2023. Patients who came for rheumatology consultation presenting with mechanical arthralgia of the lower limbs, who were obese, had radiographic images were included. All patients without radiographic images were excluded. Obesity was defined as a body mass index (BMI) greater than or equal to 30 kg/m. The Chi2 test was used to compare proportions and determine the existence of associations between osteoarthristis and obesity, obesity severity and radiographic stage of osteoarthritis as well as the functional impact. A p-value below a predefined threshold (p = 0,05) indicates a significant relationship between the variables. Result: Out of 185 patients received for osteoarthritis of the lower limbs during the study period, 136 were obese (74%). There were 115 women (84.6%) with an average age of 56.03 with a standard deviation of 12.72 years (extremes: 22 and 84 years). The main socio-professional category was the informal sector (30%). The majority of patients had a low socio-economic level (80.2%) and lived in urban areas (92.6%). The most common past medical history was hypertension (33.08%) followed by peptic ulcer disease (16.91%). Patients had a body mass index class 1 (81.6%), class 2 (15.40%) and class 3 (2.90%). The average duration of symptom progression until diagnosis was 11 months. Genu varum was the main static disorder (56.10%) and the knee joint was the dominant topography (90.4%) with a bilateral localization (80%). The average Lequesne index was greater than 8 (59.5%). The Kellgren and Lawrence radiographic stages were stage 1 (9.20%), stage 2 (46.90%), stage 3 (29.20%) and stage 4 (6.90%).

关键词： Osteoarthritis Lower Limbs Obesity Abidjan

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Epidemiological and Clinical Aspects of Hospitalized Patients with Chronic Rheumatic Disease at Cocody University Hospital in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases（风湿病与自身免疫疾病期刊） 2023年第3期

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Epidemiological, Clinical and Paraclinical Profile of Osteoarthritis of the Lower Limbs in Obese Patients at the Cocody University Teaching Hospital

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Open Journal of Rheumatology and Autoimmune Diseases（风湿病与自身免疫疾病期刊） 2024年第2期 69页

作者： Nzima Brice Kollo Aboubakar Bamba Aboubacar Sidiki Condé Nzima Hilary Ngon kanbaye Medom Ada Nina Kpami Yaya Coulibaly kan joseph Enoch koffi Ehaulier Soh Christian Louis Kouakou Mohamed Diomandé Edmond Eti

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Epidemiological and Diagnostic Features of Non-Traumatic Gonalgia in Adults in Bouake (Ivory Coast): About 140 Patients

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Open Journal of Rheumatology and Autoimmune Diseases 2023年第4期13卷 78-87页

作者： Kouakou Ehaulier Soh Christian Louis Sougué Charles Yao Konan Joe Clauvis Traore Aissata koffi joseph kan enock Goua Jean Jacques Same Bebey Francine Goupille Phillipe Daboiko Jean Claude Felix Rheumatology Department University Hospital Center Bouaké Bouaké C&#244te d’Ivoire Internal Medicine Department University Hospital Center Sour&#244 Sanou Bobo Dioulasso Burkina Faso Rheumatology Department Laquintinie Hospital Douala Cameroon Rheumatology Department University Hospital Center Tours France

Background: Non traumatic gonalgia is the second most common reason for rheumatology consultations and accounted for 15.6% of rheumatological disorders in Abidjan. Objective: The aim of this work was to study the epidemiological and diagnostic features of non-traumatic gonalgia (NTG) in a black adult population from sub-Saharan Africa. Patients and Methods: This was a five-year retrospective descriptive study (January 2014 to December 2018) of black sub-Saharan African adult patients with non traumatic gonalgia seen in the rheumatology department of the Bouake University Hospital in Côte d’Ivoire. Results: Of 2198 patients seen for rheumatological conditions, 140 had non traumatic gonalgia (6.4%). The mean age of patients was 56.13 ± 13.3 years (extremes 20 and 87 years), and the sex ratio was 0.43 (42 men and 98 women). Gonalgia without swelling was observed in 33.6% of cases. Symptoms were predominantly progressive (97.1%), chronic (82.1%) and bilateral (50%). The causes of TNM were gonarthrosis (85%), septic arthritis (7.1%), reactive arthritis (2.9%), gout (2.9%), rheumatoid arthritis (1.4%) and chondrocalcinosis (0.7%). Gonarthrosis (119/140) was bilateral in 65 patients, bi- or tri-compartmental in 83, radiographic stage (Kellgren and Lawrence) III in 80 and IV in 15. A germ was isolated in two cases of septic arthritis (methicillin-sensitive Staphylococcus aureus and Streptococcus pneumoniae). Conclusion: GNT is common in rheumatology practice in Bouake, and mainly affects women in their fifties. It is most often a chronic bilateral gonalgia, with gonarthrosis as the main etiology.

关键词： Non-Traumatic Gonalgia Gonarthrosis Bouake

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Changing Trends of Natural Resources Degradation in Kagera Basin: Case Study of Kagera Sub-Basin, Uganda

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Natural Resources 2012年第3期3卷 95-106页

作者： Casim Umba Tolo enock Amos Majule joseph Perfect Department of Biology Mbarara University Mbarara Uganda Institute of Resource Assessment (IRA) University of Dar Es Salaam Dar es Salaam Tanzania

In many respects, river basins are extremely convenient natural resources management units and hence calls for an integrated approach in case of transboundary nature. Environmental resources in Kagera basin are under great threat due to demographic factors leading to wide spread environmental degradation. Land degradation and biodiversity loss are central issues in the basin, but the extent and severity of the degradation pressures are not yet clearly illustrated and their implications largely unknown. To date, natural resource mapping in Kagera basin has been based on isolated case studies for specific purposes and not much has been done in mapping resources and classification of resources degradation by remote sensing applications considering the whole basin. In this study, basin-wide mapping approach was adopted and hot spot areas associated with natural resources use in the basin identified and trends over time established. However, this paper presents results from Kagera River sub-basin, Uganda. Mapping exercise was done by using landsat images and aerial photos of Kagera basin covering the years 1984-2002. Overall, bushland in Kagera sub-basin, Uganda increased by 78% and woodland cover showed mere 6% gain;but a 53% decrease in open woodland sub-type and 29% decrease in closed woodland. Significant shift occurred in cultivation with herbaceous crops (mainly banana) from year 1984-2002 moving from east to west of Kagera sub-basin, Uganda representing 167% increase. Area occupied by permanent swamp decreased 31%. Over the same period, land cover change detection matrix indicates main land cover changes include conversion to bushland (59.34%) followed by conversion to grassland (7.29%) and cultivated land (7.16%), with only 24.19% of the land cover remaining unchanged. It is concluded that the observed changes are, a result of human-induced factors and show unsustainable utilization of natural resources as most of the changes make the land susceptible to degradat

关键词： Natural Resources Degradation Mapping Kagera Basin Uganda

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Anaerobic bacteria and intrahepatic stones: detections of Clostridium sp. and Bacteroides fragilis

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Chinese Medical Journal 2000年第9期113卷 90-93页

作者： LIU Yanlei kan Lam Yajarayma J Tang Paul H Gumerlock Dong Ki Lee Myung Hwa Kim Sum P Lee joseph SilvaJr joseph W Leung Division of Gastroenterology and Mr & MrsCWLaw Biofilm Research Center University of CaliforniaDavis MedicalCenterSacramentoCA95817USA

To detect anaerobic bacteria Clostridium sp . and Bacteroides fragilis in intrahepatic stones by molecular genetic method Methods DNA was extracted from 59 stone samples and subjected to polymerase chain reaction (PCR) amplification targeting the 16S rRNA gene of Clostridium sp . and the glutamine synthetase gene of Bacteroides fragilis Single-strand conformational polymorphism (SSCP) analysis was performed to identify the Clostridium sp Results 16S rRNA gene sequences for Clostridium sp. were identified in 49 stones (83%, 49/59) The two most common groups were detected in 19 (41%) and 17 (37%) of the 46 samples using SSPC analysis, and 25/59 (42%) stones were tested positive for Bacteroides fragilis Conclusions Anaerobes such as Clostridium sp and Bacteroides fragilis present in intrahepatic stones and may play a role in stone formation PCR is a useful technique to detect fastidious pathogens, which are difficult to culture SSCP of PCR products is a rapid method in differentiating bacterial species

关键词： intrahepatic stone anaerobic bacteria PCR single-strand confromational polymorphism

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Field Evaluation of LED Fluorescence Microscopy for Demonstration of <i>Trypanosoma brucei rhodesiense</i>in Patient Blood

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Microscopy Research 2019年第1期7卷 1-9页

作者： enock Matovu Andrew Edielu James Ojom Ann Nanteza Charles Drago Kato Sylvain Biéler joseph Mathu Ndung’u College of Veterinary Medicine Animal Resources and Biosecurity Makerere University Kampala Uganda Lwala Hospital Soroti Uganda Foundation for Innovative New Diagnostics (FIND) Campus Biotech Chemin des Mines 9 Geneva Switzerland

Diagnosis of Trypanosoma brucei rhodesiense human African trypanosomiasis requires demonstration of parasites in body fluids by microscopy. The microscopy methods that are routinely used are difficult to deploy in resource-limited settings due to practical challenges, including lengthy and tedious procedures, and the need for specific equipment to centrifuge samples in glass capillary tubes. We report here on a study that was conducted in a rural region of eastern Uganda to evaluate new methods that take advantage of a field-deployable LED fluorescence microscope. Examination of acridine orange-stained blood smears by LED fluorescence microscopy resulted in a diagnostic accuracy that was similar to that of routine methods, while the time needed to identify parasites was shortened significantly. These findings make these new microscopy methods attractive alternatives to procedures that are currently used for diagnosis of T. b. rhodesiense human African trypanosomiasis.

关键词： Human African Trypanosomiasis Rhodesiense LED Fluorescence Microscopy Red Blood Cell Lysis Diagnosis

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Epidemiological and Diagnostic Features of Non-Traumatic Gonalgia in Adults in Bouake (Ivory Coast): About 140 Patients

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Open Journal of Rheumatology and Autoimmune Diseases（风湿病与自身免疫疾病期刊） 2023年第4期

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