检索结果-南通市图书馆

Commentary on“Desialylated Platelets Maintain Immune Quiescence through Regulating Kupffer Cells”

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2024年第3期6卷 621-623页

作者： Chen Li craig N.Morrell Aab Cardiovascular Research Institute University of Rochester School of Medicine and DentistryRochesterNYUSA Department of Pharmacology and Physiology University of Rochester School of Medicine and DentistryRochesterNYUSA Department of Medicine University of Rochester School of Medicine and DentistryRochesterNYUSA Department of Microbiology and Immunology University of Rochester School of Medicine and DentistryRochesterNYUSA Department of Pathology and Laboratory Medicine University of Rochester School of Medicine and DentistryRochesterNYUSA.

Platelets have long been studied for their roles in hemostasis and vascular injury repair. However, there is a continually evolving and deepening understanding that platelets initiate and regulate responses to tissue injury and pathogens, leading to platelets now being considered immune modulatory cells [1]. Platelets actively participate in host immune responses directly through pathogen engulfing and killing, or by regulating both innate and adaptive immune responses to infection or tissue injury [2]. Activated platelets promote inflammatory responses to tissue injury or infection by direct contact dependent interactions with immune cells and through indirect interactions via released soluble factors. However, mice that are deficient in platelets have skewed T helper cell differentiation [3] and increased vascular permeability [4], implying poorly defined roles for platelets in maintaining healthy immune homeostasis.

关键词： Platelet homeostasis Immune

Sleep-based neuronal oscillations as a physiological biomarker for Alzheimer's disease:is night time the right time?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第7期19卷 1417-1418页

作者： Jonathan Witton Erica S.Brady Michael T.craig Department of Clinical and Biomedical Sciences Faculty of Health and Life SciencesUniversity of ExeterExeterEnglandUK gladstone Institute for Neurological Disease San FranciscoCAUSA School of Psychology and Neuroscience College of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgowScotlandUK

Dementia is a devastating syndrome characterized by memory problems,confusion,and behavior changes that prevent people from performing everyday *** is the leading cause of dependency and disability amongst older people,resulting in a global economic cost of ~$1.3 *** 58 million people are currently afflicted by dementia worldwide,with Alzheimer s disease(AD) causing most(60-70%) of these cases.

关键词： Alzheimer everyday performing

Rheological properties of rare earth minerals flotation pulp in the presence of anions

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第11期42卷 2172-2182页

作者： Moonchul Jung Bogale Tadesse craig Dick Alex Logan Laurence Dyer Boris Albijanic Western Australia School of Mines Curtin University Lynas Rare Earths Ltd

Water quality has been found to significantly influence the flotation operations due to the alteration of surface properties of *** effect of cations on the flotation of RE minerals has been studied,however,there are still very limited information regarding the effect of *** present study examined the impact of specific anions such as Cl-,SO42-,and HCO3-on the flotation performance of rare earth（RE） *** study integrates flotation experiments,rheology measurements,entrainment experiments,zeta potential measurements and settling *** is observed that an increase in the concentration of these anions lead to a decrease in the recovery of RE minerals and an increase in the recovery of FeO minerals and thus negatively affecting flotation *** adverse effect is most pronounced with Cl-and least noticeable with HCO3-.An increase in the non-selective entrainment of gangue minerals is observed when the flotation pulp has higher *** reduction in the zeta potential of fine particles in the presence of these results in a higher pulp viscosity due to increased attractive forces between *** findings were verified by settling experiments and calculations based on the DLVO theory.

关键词： Flotation Rare earth ore Anions Pulp rheology Entrainment DLVO theory

Stand dynamics of old-growth hemlock forests in central Bhutan are shaped by natural disturbances

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Forest Ecosystems 2024年第4期11卷 434-447页

作者： Karma Tenzin craig R.Nitschke Kathryn J.Allen Raphael Trouve Thiet V.Nguyen Patrick J.Baker School of Agriculture Foodand Ecosystem SciencesUniversity of Melbourne500 Yarra BlvdRichmondVictoriaAustralia School of geography Planningand Spatial SciencesUniversity of TasmaniaSandy BayTasmaniaAustralia Forest Science Institute of South Vietnam 1 Pham Van Hai StreetTan Binh DistrictHo Chi Minh CityViet Nam

Understanding how past disturbances have influenced the development of forests is critical for deciphering their current structure and composition and forecasting future *** this study,dendrochronological methods were applied to uncover the disturbance history of old-growth hemlock-dominated forests in central *** of tree-ring samples from two old-growth hemlock stands,located in two different topographic settings,identified the importance of gap-phase dynamics in facilitating recruitment and growth releases and producing complex,multi-aged structure s over *** site showed evidence of a near stand-replacing disturbance in the late 1700s,while the other showed no evide nce of high-severity disturbance at any time over the last 400 *** both sites low-to medium-severity disturbances,some of which appear to be associated with cyclones originating in the Bay of Bengal,dominated the disturbance *** hemlock stands exhibited a significant positive association between cyclone occurrence and growth release events and between recruitment pulses and growth release *** 1800 to 1970 there was an increase in recruitment of angiosperm tree species at most sites and a corresponding decline in conifer *** the past 50 years there has been little new recruitment;this may be due to light limitation in the understory from shade-tolerant angiosperms and bamboo in the lower strata of these *** variations in disturbance dynamics and recruitment were observed across the study sites,suggesting that other factors,such as topography and climate,may be influencing long-term stand development *** study highlights the complex interplay between historical disturbance regimes and tree recruitment in shaping the age and size structures of old-growth hemlock forests in central *** also provides new insights into the dynamics of these forests that can be used to support effective forest conservation and management i

关键词： Forest structure Hemlock forest Himalaya Natural disturbance

Feeding ecology and interactions with mammal hosts in a symbiotic genus of birds(Buphagus spp.)in Namibia

在线全文

学校读者我要写书评

暂无评论

Avian Research 2024年第3期15卷 336-344页

作者： Michael S.Lukubwe Daniel Velarde-garcéz Fernando Sequeira Susana Lopes Adrian J.F.K.craig Vanessa A.Mata Department of Zoology and Entomology Rhodes UniversityMakhandaSouth Africa Department of Wildlife Management and Tourism Studies University of NamibiaKatima Mulilo CampusNamibia Departamento de Biologia Faculdade de CiênciasUniversidade do PortoPortoPortugal CIBIO Centro de Investigação em Biodiversidade e Recursos GenéticosInBIO Laboratório AssociadoCampus de VairãoVairãoPortugal BIOPOLIS Program in genomics Biodiversity and Land PlanningCIBIOCampus de VairãoVairãoPortugal

As the sole obligate symbiotic birds in Africa,oxpeckers offer a unique model for studying symbiotic *** to the multitrophic level they occupy and the context dependent foraging behavior they exhibit,the type of symbiotic relationship can be *** addition to providing a cleaning service to the host by removing ticks,oxpeckers frequently feed on blood,mucus,and saliva,inflicting potential damage on the ***,we used DNA metabarcoding on faecal samples to analyze the taxonomic composition of the trophic interactions of the Yellow-billed Oxpecker(Buphagus africanus)and Red-billed Oxpecker(***)in northeastern *** contrast to conventional methods,DNA metabarcoding allows for a detailed identification of dietary resources encompassing both mammal hosts and consumed arthropods within the same *** this information,we examined differences in the diet composition between oxpecker species and localities,as well as the co-occurrence between host and arthropod *** findings revealed that oxpeckers predominantly source their diet from mammals,ticks,and flies;however,ticks and flies rarely co-occur in the diet of an *** observed variability among individuals in their feeding ecology,which is strongly correlated with locality and,to a lesser extent,with the mammal *** noted a high degree of mobility between hosts within relatively short periods,with 32%of the samples showing traces of at least two mammal *** study illustrates the dynamic foraging behavior of these specialized symbiotic birds,shedding light on their potential role in pest control services and disease transmission.

关键词： Commensalism Diet DNA metabarcoding Oxpeckers Parasitism Trophic ecology

Robust Cross-Linked Na_(3)V_(2)(PO_(4))_(2)F_(3) Full Sodium-Ion Batteries

在线全文

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第1期7卷 9-20页

作者： Jinqiang gao Ye Tian Lianshan Ni Baowei Wang Kangyu Zou Yingchang Yang Ying Wang craig E.Banks Dou Zhang Kechao Zhou Huan Liu Wentao Deng guoqiang Zou Hongshuai Hou Xiaobo Ji College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083China College of Material and Chemical Engineering Tongren UniversityTongren 554300China Department of Chemistry The Chinese University of Hong KongShatinN.T.Hong Kong S.A.R.China Faculty of Science and Engineering Manchester Metropolitan UniversityManchester UK State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China School of Materials Science and Engineering Hunan Provincial Key Lab of Advanced Materials for New Energy Storage and ConversionHunan University of Science and TechnologyXiangtan 411201China School of Materials and Engineering Zhengzhou UniversityZhengzhou 450001China

Sodium-ion batteries(SIBs)have rapidly risen to the forefront of energy storage systems as a promising supplementary for Lithium-ion batteries(LIBs).Na_(3)V_(2)(PO_(4))_(2)F_(3)(NVPF)as a common cathode of SIBs,features the merits of high operating voltage,small volume change and favorable specific energy ***,it suffers from poor cycling stability and rate performance induced by its low intrinsic ***,we propose an ingenious strategy targeting superior SIBs through cross-linked NVPF with multi-dimensional nanocarbon frameworks composed of amorphous carbon and carbon nanotubes(NVPF@C@CNTs).This rational design ensures favorable particle size for shortened sodium ion transmission pathway as well as improved electronic transfer network,thus leading to enhanced charge transfer kinetics and superior cycling *** from this unique structure,significantly improved electrochemical properties are obtained,including high specific capacity(126.9 mAh g^(-1)at 1 C,1 C=128 mA g^(-1))and remarkably improved long-term cycling stability with 93.9%capacity retention after 1000 cycles at 20 *** energy density of 286.8 Wh kg^(-1)can be reached for full cells with hard carbon as anode(NVPF@C@CNTs//HC).Additionally,the electrochemical performance of the full cell at high temperature is also investigated(95.3 mAh g^(-1)after 100 cycles at 1 C at 50℃).Such nanoscale dual-carbon networks engineering and thorough discussion of ion diffusion kinetics might make contributions to accelerating the process of phosphate cathodes in SIBs for large-scale energy storages.

关键词： dual-nanocarbon networks full sodium-ion battery ion transfer kinetics Na_(3)V_(2)(PO_(4))_(2)F_(3) NASICON structure

The Performance of Small Diameter Aluminum Light Support Structures Containing Handholes under Cyclic Fatigue

在线全文

学校读者我要写书评

暂无评论

Open Journal of Civil Engineering 2024年第2期14卷 196-213页

作者： Cameron R. Rusnak Aya Al-Hamami craig C. Menzemer Department of Science Technology and Mathematics Lincoln University of Missouri Jefferson Missouri USA Auburn Science and Engineering Center Department of Civil Engineering The University of Akron Akron Ohio USA

Aluminum light poles play a pivotal role in modern infrastructure, ensuring proper illumination along highways and in populated areas during nighttime. These poles typically feature handholes near their bases, providing access to electrical wiring for installation and maintenance. While essential for functionality, these handholes introduce a vulnerability to the overall structure, making them a potential failure point. Although prior research and analyses on aluminum light poles have been conducted, the behavior of smaller diameter poles containing handholes remains unexplored. Recognizing this need, a research team at the University of Akron undertook a comprehensive experimental program involving aluminum light poles with handholes containing welded inserts in order to gain a better understanding of their fatigue life, mechanical behavior, and failure mechanisms. The research involved testing seven large-scale aluminum light poles each 8-inch diameter, with two separate handholes. These handholes included a reinforcement that was welded to the poles. Finite Element Analysis (FEA), statistical analysis, and comparison analysis with their large counterparts (10-inch diameter) were used to augment the experimental results. The results revealed two distinct failure modes: progressive crack propagation leading to ultimate failure, and rupture of the pole near the weld initiation/termination site around the handhole. The comparison analysis indicated that the 8-inch diameter specimens exhibited an average fatigue life exceeding that of their 10-inch counterparts by an average of 30.7%. The experimental results were plotted alongside the fatigue detail classifications outlined in the Aluminum Design Manual (ADM), enhancing understanding of the fatigue detail category of the respective poles/handholes.

关键词： Light Pole Handhole Cyclic Fatigue Fatigue Analysis Finite Element Analysis Statistical Analysis

Prehospital transdermal glyceryl trinitrate for ultra- acute ischaemic stroke: data from the RIgHT- 2 randomised sham- controlled ambulance trial

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2024年第1期9卷 38-49,I0035-I0046页

作者： Jason Philip Appleton Lisa J Woodhouse craig S Anderson Sandeep Ankolekar Lesley Cala Mark Dixon Timothy J England Kailash Krishnan grant Mair Keith W Muir John Potter Christopher I Price Marc Randall Thompson g Robinson Christine Roffe Else C Sandset Jeffrey L Saver Angela Shone Aloysius Niroshan Siriwardena Joanna M Wardlaw Nikola Sprigg Philip M Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Applied HealthResearch University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trials Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Faculty of Medicine The George Institute for Global HealthSydneyNew South WalesAustralia The george Institute China at Peking University Health Science Center BeijingChina Neurology Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia Department of Neurology King's College Hospital NHS Foundation TrustLondonUK Faculty of Health and Medical Sciences University of Western AustraliaCrawleyWestern AustraliaAustralia East Midlands Ambulance Service NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK Centre for Clinical Brain Sciences Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurology and Psychology University of GlasgowGlasgowUK Bob Champion Research and Education Building University of East AngliaNorwichUK Institute of Neuroscience Newcastle UniversityNewcastle upon TyneUK Department of Neurology Leeds Teaching Hospitals NHS TrustLeedsUK Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre University of LeicesterLeicesterUK Stroke Research in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK Department of Neurology Oslo University HospitalOsloNorway Research and Development Norwegian Air Ambulance FoundationOsloNorway Department of Neurology and Comprehensive Stroke Center David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Research and graduate Services University of NottinghamNottinghamUK Community and Health Research Unit University of LincolnLincolnUK

Background The effect of transdermal glyceryl trinitrate(gTN,a nitrovasodilator)on clinical outcome when administered before hospital admission in suspected stroke patients is ***,we assess the safety and efficacy of gTN in the prespecified subgroup of patients who had an ischaemic stroke within the Rapid Intervention with glyceryl trinitrate in Hypertensive stroke Trial-2(RIgHT-2).Methods RIgHT-2 was an ambulance-based multicentre sham-controlled blinded-endpoint study with patients randomised within 4hours of *** primary outcome was a shift in scores on the modified Rankin scale(mRS)at day *** outcomes included death;a global analysis(Wei-Lachin test)containing Barthel Index,EuroQol-5D,mRS,telephone interview for cognitive status-modified and Zung depression scale;and neuroimaging-determined‘brain frailty’*** were reported as n(%),mean(SD),median[IQR],adjusted common OR(acOR),mean difference or Mann-Whitney difference(MWD)with 95%*** 597 of 1149(52%)patients had a final diagnosis of ischaemic stroke;age 75(12)years,premorbid mRS>2107(18%),glasgow Coma Scale 14(2)and time from onset to randomisation 67[45,108]***‘brain frailty’was common:median score 2[2,3](range 0–3).At day 90,gTN did not influence the primary outcome(acOR for increased disability 1.15,95%CI 0.85 to 1.54),death or global analysis(MWD 0.00,95%CI-0.10 to 0.09).In subgroup analyses,there were non-significant interactions suggesting gTN may be associated with more death and dependency in participants randomised within 1hour of symptom onset and in those with more severe *** In patients who had an ischaemic stroke,ultra-acute administration of transdermal gTN in the ambulance did not improve clinical outcomes in a population with more clinical and radiological frailty than seen in previous in-hospital *** IS ALREADY KNOWN ON THIS TOPIC⇒Transdermal glyceryl trinitrate(gTN)was associat-ed with less death and dependency in those w

关键词： glasgow nitrate random

A Note of gratitude,and a Tribute to the Journal of Modern Life Writing Studies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

现代传记研究

现代传记研究 2024年第1期 19-20页

作者：克雷格·豪斯夏威夷大学传记研究中心夏威夷大学马诺阿分校

greetings and Aloha to the friends of the Journal of Modern Life Writing Studies,on this joyous *** the co-editor of Biography:An Interdisciplinary Quarterly for thirty years,and one of the people responsible for its forty-five year history,I am very familiar with what it takes to sustain an academic publication for a single year,let alone ten!Your entire editorial staff are to be congratulated,with special notice extended to my greatly-valued colleagues and lifewriting visionaries,Professors Yang and Liu.

关键词： editor alone Writing