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Postnatal development of fetuses with a single umbilical artery:differences between malformed and non-malformed infants

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World Journal of Pediatrics 2015年第1期11卷 61-66页

作者： jose vicente arcos-machancoses Purificación Marín-Reina Eugenia Romaguera-Salort Yolanda García-Camuñas Antonio Pérez-Aytés Máximo Vento Department of Pediatrics University & Polytechnic Hospital La Fe Valencia Spain Division of Neonatology University & Polytechnic Hospital La Fe Valencia Spain Department of Obstetrics & Gynecology University & Polytechnic Hospital La Fe Valencia Spain Division of Dysmorphology & Reproductive Assessment University & Polytechnic Hospital La Fe Valencia Spain

Background:The presence of a single umbilical artery(SUA)is a fetal soft marker of congenital *** the most common related malformations,there are cardiological,nephrourological and digestive anomalies,most of which are considered to have a vascular *** is an association between increased incidence of intrauterine growth retardation and adverse perinatal indicators,but whether this association is due to related anomalies or isolated SUA(SUA)is ***:We reviewed 96 cases of iSUA and non-isolated SUA(niSUA),diagnosed in a period of two years in a referral hospital for high-risk *** on prenatal explorations,including fetal ultrasonography and karyotyping,were *** was diagnosed when no malformations were found prenatally or in postnatal ***:Sixty-six newborns(68.8%)had no other anomalies and 30(31.3%)presented with a variety of malformations including heart diseases,urophaties,digestive,nervous and musculoskeletal disorders,genetic abnormalities and complex *** and nephrourological abnormalities were found to be the most frequent association with a SUA(both in 23.8%of malformed SUA newborns).Intrauterine growth restriction was not higher in iSUA newborns than in a normal *** allowed optimal prenatal diagnosis in most ***:The prognosis of the fetus with a SUA is determined by the presence of other malformations observed by an expert *** no other findings are made,only a routine physical examination should be performed in newborns,but no other complementary examinations are required.

关键词： cardiovascular abnormalities congenital abnormalities fetal growth retardation prenatal ultrasonography single umbilical artery

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