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Application of Non-destructive Testing to Evaluate the Performance of Bridges Structures

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Journal of Civil Engineering and Architecture 2017年第1期11卷 1-7页

作者： Diego Jesus de Souza Elaine Souza dos Santos Eric Pianizolli Flor gabriel Pereira Marinho Giovana Costa Reus Heloise Cristine Cezario Leticia Andrade Camara Department of Civil Engineering University of Ottawa Ottawa K2P0M1 Canada Department of Civil Construction Universidade Federal do Parana Sao Jose dos Pinhais 83040-334 Brazil Department of Civil Construction Universidade Federal do Parana Linhares 29902-190 Brazil Department of Civil Construction Universidade Federal do Parana Curitiba 80630-280 Brazil Department of Civil Construction Universidade Federal do Parana Campo Largo 83604-230 Brazil Department of Civil Construction Universidade Federal do Parana Curitiba 80060-120 Brazil

Bridges are important elements in road system and can influence the entire economy of cities and region. Usually, these structures have high financial investments for their constructions, in this way, maintenance and conservation become so important. Inspection is a technical activity that covers several operations, including performance analysis; examination; final performance report, other operations may be necessary, such as maintenance work, recovery, strengthening and rehabilitation. Technical examination together with some test methods allows a critical and parametric judgment of the bridge performance by minimizing the subjectivity of visual evaluations, and permits a more detailed diagnosis. This paper discusses the methodology to perform tests to complement the assessment recommended by DNIT （Brazilian National Department of Transport Infrastructure）, which consists only on a visual judgment. This approach provides technical basis to classify the bridges as its need and urgency of maintenance.

关键词： Non-destructive testing bridges concrete durability.

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我与《百年孤独》的美妙邂逅

新东方英语（中英文版） 2014年第7期 32-36页

作者： jose A. Carillo 宋怡秋

这是个私密的故事，我很少对外人提及，只是偶尔对有抱负的文学青年、年轻的管理者和青少年“书虫”——那些会抽出时间问我有哪些值得一读的英文书或小说的人——讲起。

关键词：《百年孤独》 How 文学青年青少年管理者

资本项目向高度流动性的金融市场开放如何导致拉美两轮半的“疯狂、惊恐和崩溃”周期

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演化与创新经济学评论 2014年第1期 14-58页

作者：何塞·加布里埃尔·帕尔玛李黎力李双双(译) 贾根良(校) 剑桥大学经济系中国人民大学经济学院密苏里大学堪萨斯分校

拉美已经历了三轮周期的资本流入,且前两轮均以重大金融危机收场。本文旨在从凯恩斯、明斯基、金德尔伯格的金融经济学的视角来剖析由这第二轮周期(包括拉美和东亚)所导致的金融危机。我将试图表明,无论这些新近开放资本项目、实现金融... 详细信息

拉美已经历了三轮周期的资本流入,且前两轮均以重大金融危机收场。本文旨在从凯恩斯、明斯基、金德尔伯格的金融经济学的视角来剖析由这第二轮周期(包括拉美和东亚)所导致的金融危机。我将试图表明,无论这些新近开放资本项目、实现金融自由化的发展中国家试图采取何等不同的路径来解决随后资本流入激增所带来的吸收问题,它们都无法逃脱金融危机的厄运。因此,这些金融危机的频发主要是源自过度流动性且'友好监管的'金融市场所固有的内在因素,从而是完全理应遭受和基本可以预见的。并且,这些危机并非只是意味着主要市场的失灵,而是表明了系统性的市场失败。它们是友好监管且过度流动性的金融市场之下自由运作的理性经济人自发行为的后果,而历史一再表明,这些经济人从过去的错误中吸取教训的能力却相当有限。

关键词：金融危机的诱因拉美东亚金融自由化新自由主义经济改革系统性市场失灵

Application of Non-Selective Herbicides in the Pre-Harvest of Wheat Damages Seed Quality

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American Journal of Plant Sciences 2018年第1期9卷 107-123页

作者： Glauber Moncon Fipke Thomas Newton Martin Ubirajara Russi Nunes Evandro Ademir Deak Jessica Deolinda Leivas Stecca jose Eduardo Minussi Winck Luiz Fernando Teleken Grando Anderson da Costa Rossato Post-Graduation Program in Agronomy at Department of Plant Science Federal University of Santa MariaSanta MariaBrazil Department of Plant Science Federal University of Santa MariaSanta MariaBrazil Laboratory of Seed Research and Teaching Federal University of Santa MariaSanta MariaBrazil Field Technical Manager Sementes Lanes Ltda.Sao GabrielBrazil Federal University of Santa Maria Santa MariaBrazil

Pre-harvest desiccation in order to minimize the time of exposure to abiotic factors after physiological maturity is a practice used in the production of quality seeds. The aim of this work was to evaluate the physical, physiological and sanitary quality of wheat seeds from plants that received non-selective herbicide application at pre-harvest. For this, the treatments were applied on pre-harvest culture. A completely randomized design was applied. We use the herbicides (glufosinate-ammonium, glyphosate and paraquat), phenological stages of herbicide application (Z-83, Z-85, Z-87, Z-92) and additional treatment (without application). The routine tests that express the physical, physiological and sanitary integrity of seeds were evaluated. For herbicide treatments, there was an 8% and 26% reduction in germination under laboratory conditions for BRS Parrudo and Sinuelo, respectively. Soil emergence was 14% higher for the control treatment, not statistically different for the Z-87 and Z-92 stages and also for the herbicides glufosinate-ammonium and glyphosate for both cultivars. The application of non-selective herbicides on wheat pre-harvest impairs the physical and physiological quality and promotes faster deterioration. Vigor is reduced under stress conditions by cold test and accelerated aging. There is no influence on seed sanity.

关键词： Glufosinate-Ammonium Glyphosate Paraquat Triticum aestivum(L)

Recent advances and new insights in the management of early-stage epidermal growth factor receptor-mutated non-small-cell lung cancer

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World Journal of Clinical Oncology 2021年第10期12卷 912-925页

作者： Miguel J Sotelo jose Luis García Cesar Torres-Mattos Héctor Milián Carlos Carracedo María Angeles González-Ruiz Xabier Mielgo-Rubio Juan Carlos Trujillo-Reyes Felipe Couñago Department of Medical Oncology Hospital María AuxiliadoraDepartment of Medical OncologyCentro Oncológico AliadaOncological Research UnitClínica San GabrielLima 15801Peru Department of Thoracic Surgery Hospital Universitario La PrincesaDepartment of Thoracic SurgeryMD Anderson Cancer CenterDepartment of Thoracic SurgeryHospital HMMadrid 28006Spain Department of Medical Oncology Hospital Nacional Guillermo AlmenaraOncological Research UnitClínica San GabrielLima 15033Peru Department of Thoracic Surgery Hospital Universitario La PrincesaMadrid 28006Spain Department of Medical Oncology Centro Oncológico AliadaLima 15036Peru Department of Radiation Oncology Hospital Universitario Virgen MacarenaSevilla 41009Spain Department of Oncology Hospital Universitario Fundación AlcorcónAlcorcón 28922MadridSpain Department of Thoracic Surgery Hospital de la Santa Creu i Sant PauBarcelona 08041Spain Department of Radiation Oncology Hospital Universitario Quirónsalud MadridHospital La LuzUniversidad Europea de MadridMadrid 28223Spain

Patients with early-stage non-small-cell lung cancer(NSCLC)are candidates for curative surgery;however,despite multiple advances in lung cancer management,recurrence rates remain *** chemotherapy has been demonstrated to significantly prolong overall survival(OS),but this benefit is modest and there is an urgent need for effective new therapies to provide a cure for more *** high efficacy of tyrosine kinase inhibitors(TKIs)against epidermal growth factor receptor-mutated(EGFR)in patients with advanced EGFR-mutated NSCLC has led to the evaluation of these agents in early stages of the *** clinical trials have evaluated the safety and efficacy of EGFR TKIs as an adjuvant treatment,in patients with resected EGFR-mutated NSCLC,and shown that they significantly prolong disease-free survival(DFS),but this benefit does not translate to ***,an interim analysis of the ADAURA trial demonstrated that,surprisingly,osimertinib improved *** led to the study being stopped early,leaving many unanswered questions about its potential effect on OS and its incorporation as a standard adjuvant treatment in this patient *** targeted agents are also being evaluated in locally-advanced disease,with promising results,although prospective studies with larger sample sizes are needed to confirm these *** this article,we review the most relevant studies on the role of EGFR TKIs in the management of early-stage EGFR-mutated NSCLC.

关键词： Non-small-cell lung cancer Early stage Epidermal growth factor receptormutated Epidermal growth factor receptor-mutated-tyrosine kinase inhibitor Adjuvant Neoadjuvant

An international survey of classification and treatment choices for group D retinoblastoma

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International Journal of Ophthalmology(English edition) 2017年第6期10卷 961-967页

作者： Christina Scelfo Jasmine H Francis Vikas Khetan Thomas Jenkins Brian Marr David H Abramson Carol L Shields Jacob Pe’er Francis Munier Jesse Berry J.William Harbour Andrey Yarovoy Evandro Lucena Timothy G Murray Pooja Bhagia Evelyn Paysse Samuray Tuncer Guillermo L Chantada Annette C Moll Tatiana Ushakova David A Plager Islamov Ziyovuddin Carlos A Leal Miguel A Materin Xun-Da Ji jose W Cursino Rodrigo Polania Hayyam Kiratli Charlotta All-Ericsson Rejin Kebudi Santosh G Honavar Vicktoria Vishnevskia-Dai Sidnel Epelman Anthony B Daniels Jeanie D Ling Fousseyni Traore Marco A Ramirez-Ortiz Ophthalmic Oncology Service Department of Surgery Memorial Sloan Kettering Cancer Center New York 10065 USA Department of Ophthalmology Weill-Cornell Medical Center New York 10065 USA Department of Vitreoretinal and Ocular Oncology Sankara Nathralaya Chennai 600066 India Ocular Ontology Service Wills Eye Hospital Thomas Jefferson University Pennsylvania 19107 USA Hadassah - Hebrew University Medical Center Jerusalem 91120 Israel jules-Gonin Eye Hospital Lausanne 1004 Switzerland USC Roski Eye Institute Children＇s Hospital of Los Angeles California 90033 USA Ocular Oncology Service Bascom Palmer Eye Institute University of Miami Miller School of Medicine Florida 33136 USA Ocular Oncology Department S.N. Fyodorov Eye Microsurgery Federal State Institution Moscow 127486 Russia Department of Ocular Oncology Instituto Nacional de Cancer Rio de Janeiro 1122 Brazil Murray Ocular Oncology and Retina Miami Children＇s Hospital Florida 33143 USA St. joseph＇s Children＇s Hospital New Jersey 07504 USA Department of Ophthalmology Baylor College of Medicine Texas 77030 USA Department of Ophthalmology Ocular Oncology Istanbul Medical Faculty Istanbul University Istanbul 34452 Turkey Oncology Department Hospital JP Garrahan Buenos Aires 1245 Argentina Department of Ophthalmology VU University Medical Center Amsterdam 1081 the Netherlands Department of Head and Neck Tumors Science Research Institute of Pediatric Oncology and Hematology N.N. Blokhin Russian Cancer Research Center Moscow 115478 Russia Pediatric Ophthalmology and Adult Strabismus Riley Hospital for Children Indiana University Medical Center Indiana 46202 USA National Oncology Center of Uzbekistan Tashkent 110508 Uzbekistan nstituto Nacional de Pediatria Coyoacan 04530 Mexico Department of Ophthalmology and Visual Science Smilow Cancer Hospital at Yale New Haven CT 06520 USA Xin Hua Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200092 China Department of Ophthalmology Santa Casa Mi

AIM： To determine which IIRC scheme was used by retinoblastoma centers worldwide and the percentage of D eyes treated primarily with enucleation versus globe salvaging therapies as well as to correlate trends in treatment choice to IIRC version used and geographic region. METHODS： An anonymized electronic survey was offered to 115 physicians at 39 retinoblastoma centers worldwide asking about IIRC classification schemes and treatment patterns used between 2008 and 2012. Participants were asked to record which version of the IIRC was used for classification, how many group D eyes were diagnosed, and how many eyes were treated with enucleation versus globe salvaging therapies. Averages of eyes per treatment modality were calculated and stratified by both IIRC version and geographic region. Statistical significance was determined by Chi-square, ANOVA and Kruskal-Wallis tests using Prism. RESULTS： The survey was completed by 29% of physicians invited to participate. Totally 1807 D eyes were diagnosed. Regarding IIRC system, 27% of centers used the Children＇s Hospital of Los Angeles （CHLA） version, 33% used the Children＇s Oncology Group （COG） version, 23% used the Philadelphia version, and 17% were unsure. The rate for primary enucleation varied between 0 and 100% and the mean was 29%. By IIRC version, primary enucleation rates were： Philadelphia, 8%; COG, 34%; and CHLA, 37%. By geographic region, primary enucleation rates were： Latin America, 57%; Asia, 40%; Europe, 36%; Africa, 10%, US, 8%; and Middle East, 8%. However, systemic chemoreduction was used more often than enucleation in all regions except Latin America with a mean of 57% per center （P〈0.0001）. CONCLUSION： Worldwide there is no consensus on which IIRC version is used, systemic chemoreduction was the most frequently used initial treatment during the study period followed by enucleation and primary treatment modality, especially enucleation, varied greatly with regards to IIRC version used and geographic r

关键词： retinoblastoma oncology retina enucleation chemotherapy intra-arterial chemotherapy ophthalmic arterychemosurgery cancer