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Enhanced depth OCT imaging of the lamina cribrosa for 24 hours

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International Journal of Ophthalmology(English edition) 2017年第2期10卷 306-309页

作者： Pedro Naranjo Bonilla Rafael Giménez Gómez David Ríos Jiménez maría Luísa Varas Fabra maría del Carmen Munoz Villanueva Rocío García Catalán Pilar Font Ugalde maría Soledad Poblador Fernández joséLuís Lancho Alonso jos.maría gallardo galera Department of Ophthalmology Reina Sofia University HospitalCordoba 14004Spain Methodological Support to Research Maimonides Institute for Biomedical ResearchReina Sofia University HospitalCordoba 14004Spain Department of Medicine UCO Maimonides Institute for Biomedical ResearchReina Sofia University HospitalCordoba 14004Spain Department of Morphological Sciences Faculty of MedicineCordoba 14004Spain

The lamina cribrosa thickness（LCT） could be affected by dynamic changes in its *** spectral-domainoptical coherence tomography（SD-OCT）,we have studied the behaviour of the laminar region in 14 young subjects over 24 *** changes in LCT were observed,depending on the time at which the measurement was taken,with the maximum thickness being observed at 7.30 p.m.,and the minimum at 7.30 *** finding could suggests a circadian pattern in the LCT thickness in healthy subjects,which could have implications for the classification,diagnosis and prognosis of both normal and glaucomatous subjects.

关键词： lamina cribrosa laminar region glaucoma optical coherence tomography twenty-four-hours

HLA B27 as Predisposition Factor to Suffer Age Related Macular Degeneration

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Cellular & Molecular Immunology 2009年第4期6卷 303-307页

作者： Enrique Villegas Becerril Rafael Gonzalez Fernandez Luis Perula Torres Manuel Santos Lacomba jose maria gallardo galera Hospital Universitario Reina Sofia Cordoba Spain Faculty of Medicine University of Cordoba Spain Hospital Universitario Reina Sofia C/Conchita Cintron n 4 Atico 2 CP 14011

To research whether specific alleles HLA class Ⅰ （HLA-A and HLA-B） and class Ⅱ （HLA-DR） are risk factors for the development of exudative type of Age Related Macular Degeneration（ARMD）, HLA antigens are expressed both in normal and affected eyes with ARMD. We designed a prospective case-controlled study. We recruited 75 patients with choroidal neovascuiarization predominantly classic or occult, secondary to ARMD, and treated with photodynamic therapy. Two hundred and fifty patients over 55 years old, without ophthalmologic pathology who went to hospital for an analytical routine check were used as control. The analysis of the data shows a significant difference between two groups. Allele HLA-B27 correlated positively with ARMD （p 〈 0.0113）. However, we didn＇t find alleles negatively associated. Thus HLA-B27 is an allele predisposed to suffer ARMD.

关键词： HLA alleles ARMD HLA B27 patient with ARMD

Multi-temporal NDVI analysis using UAV images of tree crowns in a northern Mexican pine-oak forest

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林业研究:英文版 2023年第6期34卷 1855-1867页

作者： joséLuis gallardo-Salazar marcela Rosas-Chavoya marín Pompa-García Pablito marcelo López-Serrano Emily García-Montiel Arnulfo Meléndez-Soto Sergio Iván Jiménez-Jiménez Instituto de Investigaciones Agropecuarias y Forestales Universidad Michoacana de San Nicolás de Hidalgo(UMSNH)58330 MoreliaMichoacánMexico Programa Institucional de Doctorado en Ciencias Agropecuarias y Forestales Universidad Juárez del Estado de DurangoRío Papaloapan y Blvd.DurangoValle del Sur s/n34120 DurangoDurangoMéxico Facultad de Ciencias Forestales Universidad Juárez del Estado de DurangoRío Papaloapan y Blvd.DurangoValle del Sur s/n34120 DurangoDurangoMéxico Instituto de Silvicultura e Industria de la Madera Universidad Juárez del Estado de DurangoBoulevard del Guadiana 501Ciudad UniversitariaTorre de Investigación34120 DurangoMéxico INIFAP-CENID RASPA Centro Nacional de Investigación Disciplinaria en Relación Agua-Suelo-Planta-Atmósfera Margen derecha canal Sacramento km 6.5Zona industrial35140 Gómez PalacioDurangoMexico

The use of unmanned aerial vehicles(UAV)for forest monitoring has grown significantly in recent years,providing information with high spatial resolution and temporal *** with multispectral sensors allow the use of indexes such as the normalized difference vegetation index(NDVI),which determines the vigor,physiological stress and photo synthetic activity of *** study aimed to analyze the spectral responses and variations of NDVI in tree crowns,as well as their correlation with climatic factors over the course of one *** study area encompassed a 1.6-ha site in Durango,Mexico,where Pinus cembroides,Pinus engelmannii,and Quercus grisea *** images were acquired with UAV and information on meteorological variables was obtained from NASA/POWER *** ANOVA explored possible differences in NDVI among the three *** correlation was performed to identify the linear relationship between NDVI and meteorological *** differences in NDVI values were found at the genus level(Pinus and Quercus),possibly related to the physiological features of the species and their *** grisea had the lowest NDVI values throughout the year which may be attributed to its sensitivity to relative humidity and *** the use of UAV with a multispectral sensor for NDVI monitoring allowed genera differentiation,in more complex forest analyses hyperspectral and LiDAR sensors should be integrated,as well other vegetation indexes be considered.

关键词： Multispectral images Normalized diff erence Vegetation index Phenology Unmanned aerial vehicles Multitemporal analysis

High-pressure scheelite-type polymorph of SmCrO_4: synthesis, structural characterization and magnetic properties

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Journal of Rare Earths 2010年第6期28卷 936-939页

作者： Regino Sáez-Puche Mahmoud Gamal Rabie Julio Romero de Paz josé-Manuel gallardo-Amores Esteban Climent Pascual Department of Inorganic Chemistry Faculty of Chemical Sciences Complutense University of Madrid Ciudad Universitaria

The new scheelite form of SmCrO4 oxide was obtained by heating the zircon-type SmCrO4 oxide at 4 GPa and 803 K. X-ray diffraction revealed that this scheelite SmCrO4 phase crystallized with tetragonal symmetry, S.G. I41/a and lattice parameters: a=0.50776(3) nm and c=1.15606(2) nm. This structural phase transition from zircon to scheelite involved a decreasing of around 10% in the unit cell volume. Although the Cr-O and Sm-O distances did not change very much in both zircon and scheelite polymorphs, the changes occurred in the bond angles were remarkable that appear to support the proposed reconstructive model to explain this structural zircon-scheelite phase transition. Magnetic susceptibility and magnetization measurements revealed that the scheelite SmCrO4 oxide behaved an antiferromagnetic material, where the Sm3+ and Cr5+ were simultaneously ordered. The estimated Néel temperature, TN, was 16 K and the critical field at 12 K associated with the metamagnetic transition was 3.2 T.

关键词： scheelite-type structure zircon-type structure high pressure synthesis antiferromagnetic behaviour metamagnetic transition rare earths

There is life after coking for Ir nanocatalyst superlattices

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Nano Research 2022年第8期15卷 6969-6976页

作者： Antonio J.martínez-galera Haojie Guo mariano D.Jiménez-Sánchez Stefano Franchi Kevin C.Prince josé M.Gómez-Rodríguez Departamento de Física de la Materia Condensada Universidad Autónoma de MadridMadrid E-28049Spain Instituto Nicolás Cabrera Universidad Autónoma de MadridMadrid E-28049Spain Elettra-Sincrotrone Trieste S.C.p.A. in Area Science ParkBasovizza(Trieste)34149Italy Condensed Matter Physics Center(IFIMAC) Universidad Autónoma de MadridMadrid E-28049Spain

Achieving superior performance of nanoparticle systems is one of the biggest challenges in *** major phenomena,occurring during the reactions,hinder the development of the full potential of nanoparticle catalysts:sintering and contamination with carbon containing species,sometimes called ***,we demonstrate that Ir nanocrystals,arranged into periodic networks on hexagonal boron nitride(h-BN)supports,can be restored without sintering after contamination by persistent *** restoration yields the complete removal of carbon from the nanocrystals,which keep their crystalline structure,allowing operation without *** findings,together with the possibility of fine tuning the nanocrystals size,confer this nanoparticle system a great potential as a testbed to extract key information about catalysis-mediated oxidation *** the case of the CO oxidation by O2,reaction of interest in environmental science and green energy production,the existence of chemical processes not observed before in other nanoparticle systems is demonstrated.

关键词： catalysis coke nanoparticles scanning tunneling microscopy(STM) X-ray photoemission spectroscopy(XPS)

The regional employment implications of a net-zero economy in Costa Rica under uncertainty

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Advances in Climate Change Research 2023年第6期14卷 988-999页

作者： maria joséSAUMA CHACON Alejandro MATARRITA VALVERDE Bernardo ZUNIGA ALVARADO Monica RODRiGUEZ-ZUNIGA Jairo QUIROs-TORTOS Luis ViCTOR-gallardo Pauline SCHAAL Paula CUBILLOS Thierry DUPLAN Matthieu ROBIN Slim DALI Universidad de Costa Rica San Jose 11501-2060Costa Rica Agence Frangaise de Developpement Paris 75598 France

This study estimates job creation from Costa Rica's transition to net-zero emissions by 2050,contrasting it with a business-as-usual scenario(BAU)using employment multipliers from Costa Rica's input-output *** model is soft-linked with a bottom-up technology-rich regional model of the CLEW sectors in Costa Rica.A robust decision-making-inspired approach is taken to assess the effects of uncertainty on the *** study addresses a literature gap in modeling subnational employment while accounting for long-term uncertainty and allows to identify economic activities affected by the transformation,so that policies regarding a just transition can be properly developed and stakeholders incentivized to take active participation in the *** baseline assumptions,a net-zero economy would have 135 thousand more jobs by 2050 than the BAU,equivalent to 7%of the employed population in ***-related jobs would triple by mid-21st century,and regions capitalizing on renewables would perceive the highest *** considering uncertainty,the net jobs range between 35-750 *** net positive outcomes in terms of jobs are feasible,global governance should focus efforts on policies that enhance these.

关键词： Decarbonization Environmental policy Input-output Employment multipliers Costa Rica

Novel synthetic opioids-toxicological aspects and analysis

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Forensic Sciences Research 2019年第2期4卷 111-140页

作者： Inês Tabarra Sofia Soares Tiago Rosado Joana Gonçalves Àngelo Luís Sara Malaca Mário Barroso Thomas Keller josé Restolho Eugenia gallardo Centro de Investigação em Ciências da Saude(CICS-UBI) Universidade da Beira InteriorCovilhãPortugal Laboratorio de Fármaco-Toxicologia-UBIMedical Universidade da Beira InteriorCovilhãPortugal Serviço de Química e Toxicologia Forenses Instituto Nacional de Medicina Legal e Ciências ForensesDelegac¸ão do SulLisboaPortugal Departament of Toxicology Institute of Forensic MedicineSalzburgAustria nal von minden GmbH RegensburgGermany

Over the past few years,there has been an emerging number of new psychoactive *** drugs are frequently mentioned as“legal highs”,“herbal highs”,“bath salts”and“research chemicals”.They are mostly sold and advertised on online forums and on the dark *** emerging new psychoactive substances are designed to mimic the effects of psychoactive groups,which are often abused *** synthetic opioids are a new trend in this context and represent an alarming threat to public *** the wide number of fatalities related to these compounds reported within the last few years,it is an important task to accurately identify these compounds in biologic matrices in order to administer an effective treatment and reverse the respiratory depression caused by opioid related *** dealing with fentanyl intoxication cases should consider that it could,in fact,be a fentanyl *** this reason,it is a helpful recommendation to include synthetic opioids in the routine toxicological screening procedures,including analysis in alternative matrices,if available,to investigate poly-drug use and possible tolerance to *** address this public health problem,better international collaboration,effective legislation,effective investigation,control of suspicious“research chemicals”online forums and continuous community alertness are *** article aims to review diverse reported fatalities associated with new synthetic opioids describing them in terms of pharmacology,metabolism,posology,available forms,as well as their toxic effects,highlighting the sample procedures and analytical techniques available for their detection and quantification in biological matrices.

关键词： Forensic sciences forensic toxicology new synthetic opioids biological specimens toxicity analysis

Patient Frailty Can Increase the Risk of Acute Kidney Injury after Cardiac Surgery: Pilot Study

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World Journal of Cardiovascular Surgery 2022年第10期12卷 245-255页

作者： Sergio Soto-Hopkins josé Antonio Sanchez-Lopez Erick Trujillo-Magallón Ron Leder Ana Gabriela gallardo-Hernandez Unidad Médica de Alta Especialidad en Cardiología Centro Médico Nacional Siglo XXI Mexico City M&#233xico IEEE Engineering in Medicine and Biology Mexico City M&#233xico Unidad de Investigación Médica en Enfermedades Metabólicas Centro M&#233dico Nacional Siglo XXI Mexico City M&#233xico

Background: Acute kidney injury (AKI) is a severe common postoperative complication of cardiac surgery (CS). It increases the risk of mortality by up to 80%. Therefore, it is essential to have preoperative risk evaluation tools. Frailty is a marker of deterioration of physiologic systems and may be associated with AKI. Purpose: The study aimed to determine the utility of frailty as a predictor of AKI after CS. Method: We enrolled 91 patients undergoing CS with cardiopulmonary bypass to determine if they had frailty before surgery and were associated with postoperative AKI. The diagnosis of postoperative AKI was based on the serum creatinine criteria of the Acute Kidney Injury Network classification up to 7 days following CS. Results: The incidence of postoperative AKI was 62% in the frail group and 21% in the non-frail group. Frailty was associated with a higher risk of AKI (relative risk [RR] = 3.00, 95% CI 1.56 - 5.77, p = 0.00). In regression models, there were associations between frailty and postoperative AKI. Conclusion: This study demonstrated that frailty could be a predictor for post-CS AKI. Therefore, frailty assessment should become an essential part of the preoperative evaluation to help the anesthesiologist to estimate the surgical risk and develop preoperative and transoperative strategies to preserve the renal function and improve the cardiac surgery outcome.

关键词： Cardiac Surgery Heart-Lung Machine Acute Kidney Injury Frailty Cardiopulmonary Bypass

Relationship between Tomato (Solanum lycopersicum) Nutrition and the Severity of the Vascular Fusariosis

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Agricultural Sciences 2023年第4期14卷 570-583页

作者： Mendoza-Medrano Daniel López-Orona Carlos Alfonso martínez-gallardo josé Ángel López-Urquidez Guadalupe Alfonso Angulo-Castro Azareel León-Félix josefina Agronomy Faculty Universidad Autónoma de Sinaloa Culiacán México Centro de Investigación en Alimentación y Desarrollo Culiacán México

The vascular fusariosis is one of the main obstacles in the tomato crop production. Currently, the management of the nutrient solution is presented as a control option for fusariosis, for such reason different nutrient solutions with nitrogen (N), phosphorus (P), potassium (K) and calcium (Ca) modifications;in four saladette tomato varieties Bony Best (BB), Manapal (M), Walter (W) and FLA were evaluated in this research, in order to analyze the damage caused by Fusarium oxysporum ***. lycopersici (FOL) severity. Tomato plants were inoculated with 3 FOL breeds, establishing a completely random design with a factorial arrangement with six repetitions. Disease’s severity was evaluated 30 days after the inoculation using levels of (0 - 4) of the methodology established by marlatt and Correll (1988). Afterwards, a statistical analysis was done through the Kruskal Wallis test, in which it was observed that treatments 93 (Ca 207 mg∙L-1, R3, variety BB), 95 (207 mg∙L-1 Ca, R3, variety W), 81 (0Ca, R3, BB) showed less disease severity. In the foliar analysis, the best treatments were 22 (193 mg∙L-1 N, R3, M) for N, the greatest P content was treatment 94 (207 mg∙L-1 Ca, R3, M) for K treatment three and 93 (207 mg∙L-1 Ca, R3, variety BB) greatest Ca content.

关键词： Fusarium oxysporum f.sp. lycopersici Nutrient Solution Cultural Control