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Intimate partner violence against women. Does violence decrease after the entry of the alleged offender into the criminal justice system?

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Forensic Sciences Research 2022年第1期7卷 53-60页

作者： Paulo Vieira-pinto joséIgnacio Muñoz-Barús Tiago Taveira-gomes Maria João Vidal-Alves Teresa Magalhães Department of Forensic Sciences PathologyGynaecology and ObstetricsPaediatricsInstitute of Forensic SciencesUniversity of Santiago de CompostelaSantiago de CompostelaSpain IINFAC TS-Institute of Research and Advanced Training in Health Sciences Department of SciencesCESPUUniversity Institute of Health Sciences(IUCS)GandraPortugal cFaculty of Medicine University of PortoPortoPortugal CINTESIS-Centre of Health Technology and Service Research University of PortoPortoPortugal Fernando Pessoa University PortoPortugal

Intimate partner violence(IPV)is simultaneously assumed as a serious crime and a major public health issue,having recurrences as one of its main characteristics and,consequently,re-entries of some alleged offenders in the criminal justice system(CJS).The main goal of this study is to assess if in cases of female victims of IPV,violence decreases after the first entry of the alleged offender in the CJS.A retrospective study was performed based on the analysis of police reports of alleged cases of IPV during a 4-year *** final sample(n=1488)was divided into two groups according to the number of entries in the CJS(single or multiple)followed by a comparative *** suggest that violence decreases after the first entry of alleged offenders in the ***-entries were found in only 15.5%of the cases but they were accountable for 3.3 times more crimes on ***,victims of recidivism presented more injuries and required more medical ***,a small group of alleged offenders seems to be more violent and accountable for most of the IPV crimes registered in the CJS suggesting that regardless of legal sanctions aiming to deter violence,these measures may not be enough for a certain group of *** study sustains the need for a predictive model to quantify the risk of repeated IPV cases within the Portuguese population.

关键词： Forensic sciences intimate partner violence women re-entry recidivism criminal justice system

Hypertonic saline:a brief overview of hemodynamic response and anti-inflammatory properties in head injury

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Neural Regeneration Research 2015年第12期10卷 1938-1939页

作者： Matheus Fernandes de Oliveira Fernando Campos gomes pinto Department of Neurosurgery Hospital do Servidor Público Estadual de S?o PauloIAMSPE Division of Functional Neurosurgery of the Institute of Psychiatry Hospital das ClínicasUniversidade de S?o Paulo

Hypertonic saline （HS） has been applied in several med- ical areas such as pneumology （asthma, cystic fibrosis and bronchiolytis）, endocrinology （hyponatremia） and especially in emergency medicine, in traumatic and in- flammatory/infectious disorders. It may be composed of 3% or 7.5% sodium chlorate. By far, 3% solution is the most widely studied and used solution （pinto et al., 2006, 2015; Dekker et al., 2014; Gantner et al., 2014; Shein et al., 2014）.

关键词： TBI Hypertonic saline head

High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test

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World Journal of Gastroenterology 2015年第5期21卷 1614-1620页

作者： Márcia Soares-Mota Tianny A Silva Luanda M gomes Marco AS pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman Instituto de Nutricao josué de Castro Federal University of Rio de JaneiroRio de Janeiro 21941-913Brazil Departamento de Clínica Médica Hospital Universitário Clementino Fraga FilhoFederal University of Rio de JaneiroRio de Janeiro 21941-901Brazil Nutrition and Immunology Chair ZIEL Research Center for Nutrition and Food SciencesTechnical University of MünchenFreising-Weihenstephan80333 MünchenGermany

AIM:To assess the vitamin A status of patients with Crohn's disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic *** composition was performed by densitometry by dual-energy X-ray *** A dietary intake was assessed from a semiquantitative food frequency ***:This study included 38 CD patients and 33 *** serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this *** was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel ***:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods.

关键词： Crohn's disease Vitamin A Serum retinol Relative dose response test Body composition

The Culture of Resilience： Providing Solutions for Urban Space Vulnerability to Recurrent Unfavourable Climatic Phenomena

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Journal of Civil Engineering and Architecture 2017年第10期11卷 921-932页

作者： Valderez Ferreira Fraga Ana Paula gomes M. pinto Institute of Economic (Ecex) Federal University of Rio de Janeiro Rio de Janeiro CEP 22.290-902 R J Brazil Department of Production and Civil Engineering University Unilasalle Niteroi CEP 24240-030 R J Brazil

Urban spaces vulnerable to recurrent adverse climatic phenomena present specific, consecutive problems, requiring a reflective view of their socio-spatial reality. This article presents a case study about the towns of Amadora, Greater Lisbon, and Petr6polis, Rio de Janeiro State, Brazil, which, originally, bore a common Portuguese urbanistic praxis. Their urban contexts are characterized by the occurrence of extreme risks of flooding and landslides caused by intense rainfall. Both places feature aggravation of the risks due to accelerated urban growth and disorderly land occupation. From the phenomenological perspective, what happens to the human being leads to fruitful and/or dramatic experiences. The important point is that there occurs learning for favourable action, with solutions for each individual and for ＂the other＂. Thus, it is proposed to qualitatively analyse, with a posture that values the community experience and urban practices of the towns that contribute to the development of the culture of resilience which promotes practices of prevention, precaution and vigilance founded on the experience of communities that have been exposed. Besides this, it is intended to verify challenges in the implementation of public policies aimed at sustainable urban development, those that contemplate, among others： risk management action to deal with natural disasters.

关键词： Urban spaces culture of resilience phenomenology community natural catastrophe/disaster

Chemical Constituents from Caesalpinia férrea:Identification and ^(1)H and ^(13)C Resonance Assignment

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American Journal of Analytical Chemistry 2014年第10期5卷 688-694页

作者： Islay Lima Magalhaes Francisco Chagas Lima pinto Raimundo Braz Filho Daniele Alves Ferreira Telma Leda gomes de Lemos Francisco josé Queiroz Monte Departamento de Química Organica e Inorganica Universidade Federal do CearáFortalezaBrasil Laboratório de Ciencias Químicas Centro de Ciencias TecnológicasUniversidade Estadual do Norte FluminenseCampos dos GoytacazesBrasil

In a phytochemical investigation of Caesalpinia ferrea (Leguminosae), four aromatic compounds (1-4) have been isolated and identified. Their structures have been assigned based on data provided by spectroscopic techni... 详细信息

关键词： Caesalpinia ferrea Leguminosae Aromatic Compounds Spectral Studies

Coffee and Caffeine Intake among Students of the Brazilian Northeast

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Food and Nutrition Sciences 2016年第1期7卷 30-36页

作者： Andreza gomes Penafort Isabella Barbosa Pereira Carneiro Antônio Augusto Ferreira Carioca Maria Olganê Dantas Sabry Francisco josé Maia pinto Helena Alves de Carvalho Sampaio University of Fortaleza Fortaleza Brazil State University of Ceara Fortaleza Brazil

The purpose of this study was to evaluate the pattern of intake of coffee and caffeine-containing food among students in a post-secondary institution in northeastern Brazil. We interviewed 498 students. Among these students, 72.3% (n = 360) reported to consume coffee, with a higher pre- valence among women (68.3%) and students aged between 18 and 25 years (82.8%). The student’s residence itself was the top location for taking coffee (90.6%) and the most widely used method of preparation was brewing coffee using a cloth filter (82.5%). The average intake of coffee was 199.0 ± 230.6 ml/day, with a frequency of 1.6 ± 1.4 times a day and concentration between 4% - 12%. Coffee was the main source of caffeine and the average daily intake of 147.3 ± 141.2 mg of caffeine was low. The data showed that the intake of coffee and caffeine does not represent a risk factor for the population studied. On the other hand, the scarcity of national studies on the subject points to the need of similar research about customer profile and pattern of consumption of coffee and caffeine, especially regarding the preparation technique of coffee, featuring benefits or risks for the development of chronic diseases.

关键词： Coffee Caffeine Chronic Disease

Antihyperglycemic effect of Passiflora glandulosa cav. fruit rinds flour in streptozotocin-induced diabetic mice

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Asian Pacific Journal of Tropical Medicine 2018年第9期11卷 510-517页

作者： Erlandia Alves Magalhaes Queiroz Raquel Teixeira Terceiro Paim Sandra Machado Lira jose Ytalo gomes da Silva Carla Laine Silva Lima Marcelo Oliveira Holanda Stephen Rathinaraj Benjamin Icaro Gusmao pinto Vieira Maria Izabel Florindo Guedes Biotechnology and Molecular Biology Laboratory State University of CearaFortaleza Ceara Brazil Technological Development Park(PADETEC) Federal University of CearaPici Campus Fortaleza Ceara Brazil

Objective:To investigate the effect of administration of Passiflora glandulosa(***) fruit rinds flour on streptozotocin(STZ)-induced diabetic ***:The preliminary phytochemical screening and parameters such as centesimal composition and brine shrimp toxicity were *** in vivo study Swiss female mice were divided into four groups:NC-normal control;DC-diabetic control animals receiving saline;MET-diabetic animals receiving metformin(200 mg/kg);PFRF-diabetic animals receiving *** fruit rinds flour(200 mg/kg).All of them were treated for 28 *** was used in a single dose of 120 mg/kg to establish diabetic *** weight,water and food intake,fasting blood glucose were *** analysis of pancreas and liver were performed to evaluate STZ-induced tissue ***:Phytochemical screening showed the presence of flavanones and *** *** fruit rinds flour was non-toxic by the brine shrimp *** fruit rinds flour also reduced the loss of body weight and significantly decreased food intake in the diabetic ***,a significant reduction in blood glucose was observed for 15 d and this was maintained on 21 d and 28 d when compared with diabetic ***,the *** fruit rinds flour has a favourable effect on the histopathological changes of the pancreas in STZ induced ***:It is concluded that *** fruit rinds flour is a natural product that contains potent antioxidant compounds and presents good prospects for the improvement of diabetic mellitus by reducing serum glucose levels.

关键词： Diabetes mellitus Passiflora Blood glucose Histology Streptozotocin Mice

ID7 Isolated from Bauhinia variegata Stem Inhibits Tumor Progression and Metastatic Mechanisms of Triple Negative Breast Cancer in Vivo

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Journal of Pharmacy and Pharmacology 2019年第7期7卷 368-384页

作者： Kamilla Monteiro dos Santos Izabela Natalia Faria gomes Renato joséSilva Oliveira Fernanda E.pinto Bruno Oliveira Fabrício P.Batista Rafael Cesar Russo Chagas Hélio B.Santos Ralph G.Thomé Wanderson Romao Rui Manuel Reis Maria Luiza Vilela Oliva Rosy Iara Maciel de Azambuja Ribeiro Laboratory of Experimental Pathology Federal University of Sao Joao del-Rei(UFSJ)DivinópolisMGBrazil josédo Rosário Vellano University UnifenasDivinópolisMGBrazil Molecular Oncology Research Center(CPOM) Barretos Cancer HospitalBarretosSPBrazil Petroleomic and Forensic Chemistry Laboratory Department of ChemistryFederal Institute of Espírito Santo(IFES)VitóriaESBrazil Chemistry Department Federal University of Sao PauloBrazil Tissue Processing Laboratory Federal University of Sao Joao del-Rei(UFSJ)DivinópolisMGBrazil Life and Health Sciences Research Institute(ICVS) Medical SchoolUniversity of MinhoBragaPortugal 3ICVS/3B’s-PT Government Associate Laboratory GuimaraesBragaPortugal

Background:The breast cancer has been the most common form of cancer among *** triple negative subtype represents 20%of all breast cancer cases in the world and is standing out by affecting young women and being *** main cause of death of patients with cancer is due to metastasis,which can reach the liver and ***:The activities of ID7 fraction of the stems of Bauhinia variegata *** breast cancer,lung metastasis and liver inflammatory process were ***:ID7 was characterized by *** viability of murine mammary cells(4T1)treated with ID7 was assessed by MTT,trypan blue and fluorescence assay and viability of BT-20,MDA-MB-231 and MCF-7 human breast cancer tumor lines by *** cell migration,invasion using matrigel and adhesion were *** expression of cell death proteins was quanitified by western blot and the gelatinases by *** ID7 activity of the tumor(4T1)and metastatic progession in vivo was ***:ID7 reduced the 4T1 and MDA-MB-231viability and increased the late apoptosis,inhibited the 4T1 migration and invasion,increased the 4T1 adhesion and decreased the secreted active ***7 also increased the expression of PARP,caspase-7 and caspase-8,RIP and *** vivo,the ID7 decreased the volume and weight of the tumors and decreased lung metastasis and inflammation in the *** characterization showed mainly the presence of oleic acid,myricetin,quercetin and kaempferol in ***:Thus,it was found that ID7 fraction exhibits selective antitumor and on the mechanisms of breast cancer metastasis activity,preventing lung metastasis and inflammation in the *** is suggested that fatty acids and flavonoids are correlated with such activities.

关键词： 4T1 cells MDA-MB-231 medicinal plants kaempferol gelatinases apoptosis cell viabilty in vivo

Photodynamic Therapy with Phthalomethyl D: Perspectives against SARS-CoV-2

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Journal of Biosciences and Medicines 2020年第10期8卷 104-116页

作者： Marcus Vinicius de Mello pinto carlos Henrique Machado Bittencourt Silva Aline Ronis Sampaio Miriam Viviane Baron Alexandre gomes Sancho Esteban Fortuny Lizia Fabiola Almeida Silva Felice Picariello Rogério Mendonça de Carvalho Instituto Celulare Rio de Janeiro RJ Brazil Orthopedics Universidade Federal Fluminense (UFF) Rio de Janeiro RJ Brazil Post-Graduate Program in Medicine and Health Sciences Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) Porto Alegre RS Brazil Universidade do Grande Rio (Unigranrio) Rio de Janeiro RJ Brazil Universidad Finis Terrae Clínica Diagnostra Santiago do Chile Chile Brazilian National Research Ethics Committee (Conep) Brasília DF Brazil Università degli Studi di Napoli Federico II Naples Italy Universidade Federal de Uberlandia MG Brazil

Background: Photodynamic therapy (PDT) is the generation of cytotoxic agents through the dynamic interaction between a photosensitizer excited by light at a specific wavelength. When associated with phthalocyanines, they are efficient in incorporating target cells and exhibiting high rates of triplet generation. This study aimed to characterize PDT associated with the phototherapeutic agent Phthalomethyl D, developed by the authors, in the process of repair, healing and immune improvement for possible application against SARS-CoV-2. Methods: Sixty-nine mice were used, divided into 2 groups: GI, treated with ILIB laser, without a phototherapeutic agent, and subjected to surgery for viral induction;GII, same as GI plus association of Phthalomethyl D. They were divided into subgroups and reevaluated at 7, 14, and 21 days, and then divided into 3 subgroups of 6 animals each, subjected to treatment at 24 h, 48 h, 72 h, 5 and 7 days. Results: Both groups had a high rate of partial incision closure and acute inflammatory control. Microscopically, there was a greater amount of amorphous fundamental substance, fibrocytes, fibroblasts, and giant cells and reduction in the number of keratinocytes, in the amount of keratin, and epidermal thickness in GII than in GI. Conclusions: PDT with Phthalomethyl D stimulates the processes of healing/repair and immunomodulation during viral infection, initially favoring the inflammatory response and, after 21 days, contributing to the anti-inflammatory response profile, making this approach possible in the treatment of individuals infected with SARS-CoV-2.

关键词： Photodynamic Therapy Coronavirus Phthalocyanines Methylene Blue Vitamin D Phthalomethyl D