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Problems,assumptions and solutions in locomotive design,traction and operational studies

Railway Engineering Science 2022年第3期30卷 265-288页

作者： Maksym Spiryagin Qing Wu Oldrich Polach John Thorburn Wenhsi Chua Valentyn Spiryagin Sebastian Stichel Sundar Shrestha esteban Bernal Sanjar Ahmad Colin Cole Tim McSweeney Centre for Railway Engineering Central Queensland UniversityRockhampton 4702Australia Independent Consultant Neuhausen am RheinfallSwitzerland Progress Rail NewcastleAustralia BHP Port HedlandAustralia Engineering Centre for Railway Transport SkolkovoRussian Federation KTH Royal Institute of Technology StockholmSweden

Locomotive design is a highly complex task that requires the use of systems engineering that depends upon knowledge from a range of disciplines and is strongly oriented on how to design and manage complex systems that operate under a wide range of different train operational conditions on various types of *** that field investigation programs for locomotive operational scenarios involve high costs and cause disruption of train operations on real railway networks and given recent developments in the rollingstock compliance standards in Australia and overseas that allow the assessment of some aspects of rail vehicle behaviour through computer simulations,a great number of multidisciplinary research studies have been performed and these can contribute to further improvement of a locomotive design technique by increasing the amount of computer-based *** paper was focused on the presentation of the all-important key components required for locomotive studies,starting from developing a realistic locomotive design model,its validation and further applications for train *** integration of all engineering disciplines is achieved by means of advanced simulation approaches that can incorporate existing AC and DC locomotive designs,hybrid locomotive designs,full locomotive traction system models,rail friction processes,the application of simplified and exact wheel-rail contact theories,wheel-rail wear and rolling contact fatigue,train dynamic behaviour and intrain forces,comprehensive track infrastructure details,and the use of co-simulation and parallel *** cosimulation and parallel computing approaches that have been implemented on Central Queensland University’s High-Performance Computing cluster for locomotive studies will be *** confidence in these approaches is based on specific validation procedures that include a locomotive model acceptance procedure and field test *** problems and limitations presented in locomot

关键词： Locomotive Design Simulation Virtual prototyping Digital twin Traction Braking Wheel-rail wear Damage

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Lenormandins A—G,new azaphilones from Hypoxylon lenormandii and Hypoxylon jaklitschii ***.,recognised by chemotaxonomic data

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Fungal Diversity 2015年第2期71卷 165-184页

作者： Eric Kuhnert Frank Surup esteban B.Sir Christopher Lambert Kevin D.Hyde Adriana I.Hladki Andrea I.Romero Marc Stadler Department of Microbial Drugs Helmholtz-Zentrum für Infektionsforschung GmbHInhoffenstrasse 738124 BraunschweigGermany German Centre for Infection Research(DZIF) partner site Hannover-Braunschweig38124 BraunschweigGermany Fundación Miguel Lillo Institute of MycologyMiguel Lillo 251San Miguel de Tucumán 4000TucumánArgentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET) Av.Rivadavia 1917Buenos Aires C1033AAJArgentina Institute of Excellence in Fungal Research and School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Department of Biodiversity and Experimental Biology University of Buenos AiresInt.Güiraldes 2620Buenos Aires C1428EHAArgentina

Seven new azaphilone pigments named lenormandins A–G were isolated from stromata(fruiting bodies)of the xylariaceous fungus,Hypoxylon lenormandii using preparative High Performance Liquid Chromatography(HPLC)and their structures were elucidated by NMR spectroscopy,high resolution mass spectrometry and other spectral *** occurrence in herbarium specimens(including various type materials collected in the 19th and early 20th century)and several fresh collections was studied by analytical HPLC with diode array and mass spectrometric detection(HPLC-DAD/MS),revealing that this group of pigments is specific for Hypoxylon lenormandii from various geographic regions and otherwise only occurs in closely related taxa,*** and an undescribed fungus from Sri Lanka,for which we propose the name *** status of the new species was established by using molecular phylogenetic data based on ITS and partial beta-tubulin sequences,and by detailed morphological studies.

关键词： Chemotaxonomy Hypoxylon Phylogeny Secondary metabolites Systematics Xylariaceae

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The Neutron and Dark Matter in the Standard Model of Particle Physics

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Journal of High Energy Physics, Gravitation and Cosmology 2022年第2期8卷 402-416页

作者： Leandro Meléndez Lugo esteban Chávez Alarcón Instituto Nacional de Investigaciones Nucleares Centro Nuclear de México Departamento de Física La Marquesa Ocoyoacac Estado de México México

The existence of the neutron, originally postulated to justify the stability of the nucleus, is very similar to the postulation of Dark Matter to give stability to galaxies and galaxy clusters. However, the existence of the neutron has been proven as an important part of the nucleus that is linked within its integral structure in the Standard Model of Particle Physics. The Standard Model that began with the electron and the proton, currently, with more than one hundred particles, shows in some parts, cracks that induce to reconsider the veracity of the theories and models. Here it is established that all theories are to some extent false and therefore, so will any model, which is always a specific part of the theory. Also, like several other things, by means of a mathematical calculation, it is clarified why, it has not been possible to incorporate the Dark Matter within the Standard Model. Furthermore, it is reliably demonstrated that the introduction of the Dark matter postulate is superfluous and that the high speeds of stellar rotation determined experimentally are analytically explained with the stellar dynamics described here.

关键词： Neutron Standard Model Dark Matter Rotational Speed Stellar Dynamics

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Phylogenetic and chemotaxonomic resolution of the genus Annulohypoxylon(Xylariaceae)including four new species

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Fungal Diversity 2017年第4期85卷 1-43页

作者： Eric Kuhnert esteban B.Sir Christopher Lambert Kevin D.Hyde Adriana I.Hladki Andrea I.Romero Manfred Rohde Marc Stadler Department of Microbial Drugs Helmholtz-Zentrum fur Infektionsforschung GmbHInhoffenstrasse 738124 BrunswickGermany German Centre for Infection Research(DZIF) partner site Hannover-Braunschweig38124 BrunswickGermany Fundacion Miguel Lillo CONICETInstitute of MycologyMiguel Lillo 251San Miguel de Tucuman 4000TucumanArgentina Fundacion Miguel Lillo Institute of MycologyMiguel Lillo 251San Miguel de Tucuman 4000TucumanArgentina Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Instituto de Micologia y Botanica(INMIBO) UBACONICETDepto.Biodiversidad y Biologia ExperimentalFCENAv.Int.Guiraldes 2620C1428EHA Ciudad Autonoma de Buenos AiresArgentina Central Facility for Microscopy Helmholtz-Zentrum fur Infektionsforschung GmbHInhoffenstrasse 738124 BrunswickGermany

This study deals with an extensive evaluation focusing on phylogenetic and chemotaxonomic infrageneric relationships of the genus Annulohypoxylon(Xylariaceae,Ascomycota),whose species are ubiquitously associated with seed plants as endophytes and saprotrophs in all forested areas of the *** evidence from phylogenetic,chemotaxonomic and morphological data,various varieties within the genus are raised to species level,leading to the new combinations for ***(:*** ***),***(:*** ***),and ***(:*** ***).Annulohypoxylon substygium *** applied for *** *** the four new tropical and subtropical species ***,***,*** and *** are ***,*** is excluded from the genus as its morphological characters disagree with the generic concept,the recently erected *** is synonymized with *** and *** has been reassigned to the genus *** addition,the key taxa *** and *** have been reinvestigated and epitypes have been *** the first time,a dichotomous key to the genus is provided.A phylogenetic b-tubulin tree in conjunction with stromatal HPLC profiles clearly shows that Annulohypoxylon comprises two distinct *** ***/multiforme group might eventually warrant segregation into a new genus as further molecular data become available.

关键词： β-Tubulin Biodiversity Chemotaxonomy Phylogeny Systematics Xylariales

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父母苯暴露与儿童白血病危险性的系统综述与meta分析

父母苯暴露与儿童白血病危险性的系统综述与meta分析

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作者： Edgar esteban Bustamante Angel 东南大学

学位级别：硕士

背景:苯是作为一种挥发性有机化合物,广泛应用于生产和生活中,如干洗、油漆、印刷、橡胶和制鞋业等多个行业,有机溶剂接触是苯暴露的最重要来源之一,研究发现苯暴露与相关职业人群白血病的发生有密切关联。苯可在职业暴露的成年人中引... 详细信息

背景:苯是作为一种挥发性有机化合物,广泛应用于生产和生活中,如干洗、油漆、印刷、橡胶和制鞋业等多个行业,有机溶剂接触是苯暴露的最重要来源之一,研究发现苯暴露与相关职业人群白血病的发生有密切关联。苯可在职业暴露的成年人中引起急性骨髓细胞性白血病和其他血液癌,包括急性淋巴白血病,慢性淋巴白血病,多发性骨髓瘤和非霍奇金淋巴瘤。然而,苯的长期暴露是否可导致儿童患白血病风险增加的证据还有待进一步的阐明。目的:本研究首次通过meta分析研究父母苯(或有关溶剂)暴露接触与其子女患白血病的关联。方法:通过系统综述收集有关成人苯和有机溶剂暴露及其与儿童白血病进一步发生关系的文献。通过电子数据库搜索收集病例对照研究,然后按照PRISMA声明进行筛选。提取数据并收集以创建数据集;其研究随后使用纽卡斯尔-渥太华量表进行质量评估(NOS)进行评估。使用随机效应模型对暴露于苯或溶剂的两个人群(即父母)进行荟萃分析,以计算汇总的效应量ES(比值比)和数据集的95%CI。使用希金斯(Higgins)的I2测试,敏感性分析和亚组分析评估了母亲和父亲暴露组的变量暴露类型(苯或有机溶剂)和白血病类型(未分类的白血病,急性髓系白血病(AML),急性淋巴细胞白血病(ALL)和急性非淋巴细胞白血病(ANLL)的异质性。还使用Begg和Egger检验评估发表偏倚的存在。所有统计分析均使用STATA12软件进行,p值<0.05被认为具有统计学意义。结果:荟萃分析包括14个病例对照研究,其中64%的研究(n=9)评估了父母苯暴露和36%(n=5)的研究评估了父母溶剂暴露。在总共14项研究中,有12项研究涉及母亲暴露,10项涉及父亲暴露。研究共获得28533例白血病病例和45285例对照。对于母亲暴露而言,儿童期白血病患儿的总体ES为1.39(1.02.89),而父亲暴露的ES则为1.18(0.89.55),两组的异质性均较高。当进行亚组分析时,母亲苯暴露的ES为1.75(1.17.61),而父亲苯暴露为ES=1.27(1.03.57);两者对溶剂暴露均无统计学意义。母亲苯暴露的白血病类型的结果与AML病例ES=1.80(1.15.82)和ALL病例ES=1.48(1.10.00)有关;父亲苯暴露为AML病例为ES=1.51(1.08.12),ALL病例为ES=1.19(0.91.56),异质性检验发现,溶剂分组、未分类白血病和母亲暴露的急性淋巴细胞白血病存在显著的异质性。敏感性分析未显示两组的总体效应大小有显着变化;对于发表偏倚,漏斗图显示了父亲暴露组的右偏不对称,而Begg和Egger的检验没有显示有显著的差异。结论:父母苯暴露可增加儿童患白血病的风险,其中母亲暴露的风险更高。父母苯暴露都与儿童AML发生的显著相关,母亲苯暴露与ALL发生显著相关。父母暴露于溶剂与儿童期白血病发生风险之间没有发现显著关联。进一步的研究需要确定父母苯暴露与儿童白血病的作用与机制。

关键词：儿童白血病急性淋巴细胞白血病(ALL) 急性髓系白血病(AML) 父母苯暴露职业苯暴露溶剂暴露挥发性有机化合物

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Establishing Profiles for Systems Engineering Standards: A Great Help for Companies to Manage Their Processes

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Frontiers of Engineering Management 2014年第3期1卷 297-303页

作者： Rui Xue Claude Baron Philippe esteban Qiang Zhang CNRS LAAS 7 avenue du colonel Roche F-31400 Toulouse France Univ de ToulouseINSA LAAS F-31400 Toulouse France CNRS LAAS 7 avenue du colonel Roche F-31400 Toulouse France Univ de ToulouseUPS LAAS F-31400 Toulouse France LPOID Hefei University of Technology

In this paper, we discuss how to establish profiles of system engineering standards for companies. To define an appropriate system engineering standard for a company, this paper presents a detailed comparison between the current releases of the main system engineering sta-ndards(ANSI/EIA-632, ISO/IEC-15288 and IEEE-1220), and explains how to choose the most adapted one according to the company practices. When no standard completely corresponds, the paper illustrates how to elaborate a tailor-made standard on the basis of specific required characteristics of the company or of the project, following a multi-standard approach, leading to extend and adapt a sta-ndard by importing some elements from another.

关键词： system engineering analysis comparison systems engineering management process multi-standards approach

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Dynamics of canopy-dwelling arthropods under different weed management options,including glyphosate,in conventional and genetically modified insect-resistant maize

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Insect Science 2021年第4期28卷 1121-1138页

作者： esteban García-Ruiz Guillermo Cobos Ismael Sánchez-Ramos Susana Pascual María-Cristina Chueca María-Concepción Escorial Inés Santín-Montanyá Íñigo Loureiro Manuel González-Núñez Plant Protection Department Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria(INIA)MadridSpain

The use of genetically modified varieties tolerant to herbicides(HT varieties)and resistant to insects(Bt varieties)in combination with application of a broad-spectrum herbicide such as glyphosate could be an effective option for the simultaneous control of weeds and pests in ***,the possible impact of these tools on nontarget arthropods still needs to be *** a field study in central Spain,potential changes in populations of canopy-dwelling arthropods in Bt maize under different weed management options,including glyphosate application,were ***-dwelling arthropods were sampled by visual inspection and yellow sticky *** Bt variety had no effect on any group of studied arthropods,except for the expected case of corn borers—the target pests of Bt *** the effects of herbicide regimes,the only observed difference was a lower abundance of Cicadellidae and Mymaridae on yellow sticky traps in plots not treated with pre-emergence *** effect was especially pronounced in a treatment involving two glyphosate *** decrease in Cicadellidae and Mymaridae populations was associated with a higher density of weeds in plots,which may have hindered colonization of the crop by *** differences,however,were only significant in the last year of the *** low likelihood of the use of glyphosate-and herbicide-tolerant varieties for weed control triggering important effects on the nontarget arthropod fauna of the maize canopy is discussed.

关键词： Bt maize canopy-dwelling arthropods GMHT maize glyphosate herbicide management parasitoids

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关于研究和机器人:让偶然的发现说得通

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英国医学杂志中文版 2022年第10期25卷 555-556页

作者： Juan Victor Ariel Franco Santiago esteban 夏鹏(译) BMJ Eridence-Based Medicine Information Management and Health Statistics Office Hospital Italiano de Buenos AiresArgentina 中国医学科学院北京协和医院

当我们解读医疗相关研究时,我们必须确保人工智能的应用带来的是帮助而非伤害。面对困惑的主人Donovan和Powel,机器人QT-1(Cutie)说道,“我,一个理性的存在,能够从先天的原因中推导出真理。而你们,尽管智慧却不理智,则需要一个存在的理... 详细信息

当我们解读医疗相关研究时,我们必须确保人工智能的应用带来的是帮助而非伤害。面对困惑的主人Donovan和Powel,机器人QT-1(Cutie)说道,“我,一个理性的存在,能够从先天的原因中推导出真理。而你们,尽管智慧却不理智,则需要一个存在的理由。”这是伊萨克·阿西莫夫经典小说《我,机器人》(I,Robot)1中的一幕。在书中,在人工智能(AI)的强大支持下,反叛的机器人控制了一个空间站,他们相信人类过于弱小,无法创造出机器人这样的高等“生物”。

关键词：机器人控制 Robot 阿西莫夫 Cut 伊萨克 QT 《我,机器人》存在的理由

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NASA’s Pioneer Spacecraft Anomaly, Heat, Dark Matter and a Probable Persuasive Genesis

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Journal of High Energy Physics, Gravitation and Cosmology 2023年第4期9卷 1356-1373页

作者： Leandro Meléndez Lugo esteban Chávez Alarcón Instituto Nacional de Investigaciones Nucleares Centro Nuclear de M&eacutexico Ciudad de M&eacutexico M&eacutexico Departamento de Fí sica La Marquesa Ocoyoacac Ciudad de M&eacutexico M&eacutexico

An analysis is performed on what is known as the anomaly of NASA’s probe spacecraft. It explains why this additional acceleration can hardly be caused by the heat emitted by the electronic equipment of the spacecraft or by the dark matter that the Solar System could contain. Additionally, the correct stellar dynamics are mathematically demonstrated to explain the high speed of stellar rotation directly in galaxies and to show that this dynamics governing galaxies is very different from the dynamics of the Solar System. This also demonstrates the superfluity of postulating the existence of Dark Matter at the galactic level. It is concluded that the anomaly of the Pioneer spacecraft is relatively feasible as a product of an explainable difference between the modeling of the 70s and the real sources of the gravitational field of the Solar System. Therefore, it is claimed that there were sources of gravitational field that were not included in the original modeling because they were unknown at the time. Finally, a particular distribution of the disperse Solar System mass is proposed that could represent the sources of the field that give a plausible explanation for the NASA spacecraft anomaly.

关键词： Dark Matter Pioneers 10 and 11 Galactic Radial Velocity Gravitation Radiation Pressure

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影响秘鲁移动购物使用意向的行为因素研究

影响秘鲁移动购物使用意向的行为因素研究

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作者： Martin esteban Tello Quiche 哈尔滨工业大学

学位级别：硕士

在过去几年中,小到家庭购买大到跨洲银行交易,电子商务在人们的日常交易中发挥了至关重要的作用。其中,移动商务作为当今最流行和发达的电子商务之一,在愈发丰富多元的电子商务中,以其独特的功能,如即时连接和定位服务,受到学者们的广... 详细信息

在过去几年中,小到家庭购买大到跨洲银行交易,电子商务在人们的日常交易中发挥了至关重要的作用。其中,移动商务作为当今最流行和发达的电子商务之一,在愈发丰富多元的电子商务中,以其独特的功能,如即时连接和定位服务,受到学者们的广泛关注。以消费者视角,移动商务被定义为通过智能终端进行的交易和业务,这些移动终端包括智能手机,平板电脑和连接移动网络的可穿戴设备等。移动商务以其独特功能为消费者带来了诸多便利,如提高他们网上购物的效率等。同时,由于其高度个性化和精准的定位服务,它也成为了针对特定内容交付的一个重要工具。随时随地皆可使用的智能手机使消费者进入了数字信息的新时代,这也正是营销人员为了接触潜在客户而利用的一个功能。数据显示,电子商务用户在2019年已高达19.2亿人,预计2021年数字买家将达到21.4亿人。全球智能手机用户年度数量的增长,也印证了这一趋势。目前,在全球移动商务排名中,中国、美国、英国、日本和西欧国家在全球移动商务中遥遥领先,拉丁美洲国家排名靠后。拉丁美洲国家中,巴西,阿根廷和墨西哥处于领军地位,即便如此,这些国家与移动商务发达国家相比,其市场份额也极小。以秘鲁为例,该国的移动购物仍处于初级阶段。世界各地的学者对消费者决策和电子商务的引擎力进行了广泛研究,然而对影响发展中国家消费者接受移动购物因素方面的研究还很缺乏。至今还没有学者以秘鲁作为具体案例,进行这方面的研究。学者们亟待在移动广告接收领域进行更加深入的研究,至今这方面的研究仍然很少。深入了解移动商务中影响消费者购买决策的因素至关重要,以此可为消费者提供高质量的相关信息和具有实用价值的广告。本研究旨在通过利用已有的理论和模型来衡量技术的接受程度,研究影响秘鲁移动商务接受程度的态度和行为因素。应用如下模型和理论,如Technology Acceptance Model(TAM),Unified Theory of Acceptance and Use of Technology(UTAUT),感知安全的风险因素,以及移动购物的一个重要决定因素,“即时连接”。从拉丁美洲接受或使用移动商务意向的文献来看,在该领域尚未发现任何相关研究。值得一提的是,一项基于哥伦比亚的研究曾试图解释该地电子商务的接受程度,此外,在针对巴西的一项研究中,有学者探讨了该地区采用移动支付的意向。有一些学者应用用TAM(Technology Acceptance Model)和感知安全及信任等风险因素来解释和模拟电子商务的接受度,研究发现信任度是哥伦比亚人进行网上购物最重要的因素。该研究人员同时建议应进一步调查诸如“创新性”和移动商务扩展等其他影响因素。考虑到这一点,在本研究中,纳入“即时连接”以此来丰富对拉丁美洲研究机构接受电子商务的差异性分析,这对于本研究具有重要意义和贡献。由于移动购物的便捷性和移动性,“即时连接”是移动商务区别于电子商务的最大优势。与以往接受新技术的研究一样,本研究应用了TAM模型及其核心决定因素。本研究的核心决定因素是“感知易用性”和“感知有用性”。一些研究发现“习惯”这一因素对技术使用有直接影响。就这一点而言,本文将研究“习惯”因素对秘鲁人口使用移动商务意愿的影响,模型中增加了“习惯”这一因素来解释移动商务的接受程度,并将之与亚洲、欧洲和美国的研究的结果进行对比。在南美国家的背景下,将“感知安全”作为手机使用意愿的决定性因素十分重要。研究表明,腐败和不安全程度越高的国家,信任和安全感越低。在低安全性和低信任感的社会中,人们过于犹豫和谨慎,这将减少甚至阻碍企业和社会合作。在移动商务的具体案例中,这可能是秘鲁移动商务活动减少的一个重要原因。数据显示,南美洲国家的不安全性和腐败程度最高。综上所述,在解释了本研究的动机之后,以下研究问题有待回答:决定秘鲁智能手机移动商务使用意向的因素有哪些?本研究的实验部分基于位于秘鲁特鲁希略市进行的一项调查,实验对象由不同职业的人组成,如学生,员工,个体经营者等。在调查过程中受访者自愿参与,且没有获得奖励或补偿。受访者已被告知本调查仅用于学术研究,调查中所涉及的任何信息不会提供给第三方。最后,在提交的240份问卷中,210份问卷完整有效并可被作为最终样本(N=210)。最终样本中男性受访者占57%,女性占43%,受访者年龄范围为18-24岁。基于实验模型得出如下假说:H1:大范围的手机使用“习惯”将增加移动购物的“感知有用性”。H2:大范围的手机使用“习惯”将增加其移动购物的“感知易用性”H3:手机使用中“感知易用性”的增加与“感知有用性”成正比。H4:手机使用中“感知有用性”的增加与移动购物的“使用意图”成正比。H5:“感知易用性”的增加与移动购物的“使用意图”成正比。H6:“即时连接”的增加与移动购物的“使用意图”成正比。H7:大范围的

关键词： Mobile commerce in Peru consumer's acceptance Perceived security Instant Connectivity Habit of use of Technology

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