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Physiological dormancy broken by endozoochory:Austral parakeets(Enicognathus ferrugineus)as legitimate dispersers of calafate(Berberis microphylla)in the Patagonian Andes

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Journal of Plant Ecology 2020年第5期13卷 538-544页

作者： Carolina Bravo Daniel Chamorro Fernando Hiraldo Karina Speziale Sergio A.lambertucci josél.tella Guillermo Blanco Department of Evolutionary Ecology Museo Nacional de Ciencias NaturalesCSICJoséGutiérrez Abascal 228006 MadridSpain Centre d’Etudes Biologiques de Chizé UMR 7372CNRS and La Rochelle UniversitéF-79360 Beauvoir-sur-NiortFrance Departamento de Ciencias Ambientales Universidad de Castilla-La ManchaAv.Carlos III s/n45071 ToledoSpain Department of Conservation Biology Estación Biológica de DoñanaCSICAmérico Vespucio 2641092 SevillaSpain Grupo de Investigaciones en Biología de la Conservación Departamento de EcologíaINIBIOMA(CONICET-National University of Comahue)Pasaje Gutiérrez 11258400 BarilocheArgentina

Aims Seed dispersal by endozoochory is an important process in plant regeneration and the establishment of new *** with dormancy may especially benefit after disperser gut ***,the ways in which gut passage affect the germination of plant species with physiological dormancy remain ***,we experimentally assessed the mutualistic interaction between the Austral parakeet(Enicognathus ferrugineus)as a disperser of calafate(Berberis microphylla),a thorny bush inhabiting the understory of the Austral temperate forests of South America with seeds that are characterized by deep physiological *** Germination success and viability of calafate seeds obtained from faeces and from intact fruits were tested under four treatments:(i)digested seeds,(ii)digested seeds with faecal extract,(iii)intact seeds from fruit and(iv)intact seeds from fruit with *** Findings About 65%of the Austral parakeet droppings contained calafate *** of seeds did not differ between ***,germination was significantly higher in digested seeds than in intact seeds from fruits,while no difference was found between faecal and pulp *** faecal matter nor fruit pulp provided seeds with any ecological advantages derived from enhancing germinability,but did confer some disadvantage in germination *** matter is expected to be completely lacking around seeds after several months under snow before germinating in the following spring,given intense washing due to persistent rain and the spring thaw in the Patagonian *** higher germinability along with faster germination of digested seeds supports the hypothesis of a legitimate mutualistic interaction between Austral parakeets and *** hypothesized that the passage through the disperser digestive tract might break physiological dormancy as differences in germinability between ingested and non-ingested *** results highlight the relevant role of endoz

关键词： seed dispersal Austral forest mutualism gut passage viability germination success germinability

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Nesting innovations allow population growth in an invasive population of rose-ringed parakeets

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Current Zoology 2022年第6期68卷 617-626页

作者： Dailos HERNANDEZ-BRITO jose l.tella Guillermo BlANCO Martina CARRETE Department of Conservation Biology Donana Biological Station(CSIC)Calle Americo Vespucio26Sevilla 41092Spain Department of Evolutionary Ecology Museo Nacional de Ciencias Naturales(CSIC)Calle JoseGutierrez Abascal2Madrid 28006Spain Department of Physical Chemical and Natural SystemsUniversidad Pablo de OlavideCarretera de Utrerakm 1Sevilla 41013Spain

Certain traits of recipient environments,such as the availability of limiting resources,strongly determine the establishment success and spread of non-native *** limitations may be overcome through behavioral plasticity,allowing them to exploit alternative ***,we show how a secondary cavity nester bird,the rose-ringed parakeet Psittacula krameri,innovates its nesting behavior as a response to the shortage of tree cavities for nesting in its invasive range in Tenerife(Canary Islands).We observed that some breeding pairs excavated their own nest cavities in palms,thus becoming primary cavity nester,whereas others occupied nests built with wood sticks by another invasive species,the monk parakeet Myiopsitta *** use of these novel nesting strategies increased the number of breeding pairs by up to 52%over 6 years,contributing to a 128.8%increase of the whole *** nests were located at greater heights above ground and were more aggregated around conspecifics but did not result in greater breeding success than natural *** of monk parakeet colonies by rose-ringed parakeets also benefited the former species through a protective-nesting association against nest *** results show how an invasive species innovate nesting behaviors and increase nest-site availability in the recipient environment,thus facilitating its population growth and invasion *** behavioral innovations in other invasive rose-ringed parakeet populations may be overlooked,and should be considered for effective management plans.

关键词： antipredator response behavioral flexibility biological invasions cavity nesters nesting innovation reproductive success

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Mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： joséM.Izquierdo Centro de Biología Molecular Severo Ochoa(CBM) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： latin potential lasting

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The emerging role of mesenchymal stem cell-derived extracellular vesicles to ameliorate hippocampal NlRP3 inflammation induced by binge-like ethanol treatment in adolescence

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Neural Regeneration Research 2025年第4期20卷 1153-1163页

作者： Susana Mellado María joséMorillo-Bargues Carla Perpiñá-Clérigues Francisco García-García Victoria Moreno-Manzano Consuelo Guerri María Pascual Department of Physiology School of Medicine and DentistryUniversity of ValenciaValenciaSpain Bioinformatics and Biostatistics Unit Príncipe Felipe Research CenterValenciaSpain Neuronal and Tissue Regeneration laboratory Príncipe Felipe Research CenterValenciaSpain

Our previous studies have reported that activation of the NlRP3(NOD-,lRR-and pyrin domain-containing protein 3)-inflammasome complex in ethanol-treated astrocytes and chronic alcohol-fed mice could be associated with neuroinflammation and brain *** stem cell-derived extracellular vesicles(MSC-EVs)have been shown to restore the neuroinflammatory response,along with myelin and synaptic structural alterations in the prefrontal cortex,and alleviate cognitive and memory dysfunctions induced by binge-like ethanol treatment in adolescent *** the therapeutic role of the molecules contained in mesenchymal stem cell-derived extracellular vesicles,the present study analyzed whether the administration of mesenchymal stem cell-derived extracellular vesicles isolated from adipose tissue,which inhibited the activation of the NlRP3 inflammasome,was capable of reducing hippocampal neuroinflammation in adolescent mice treated with binge *** demonstrated that the administration of mesenchymal stem cell-derived extracellular vesicles ameliorated the activation of the hippocampal NlRP3 inflammasome complex and other NlRs inflammasomes(e.g.,pyrin domain-containing 1,caspase recruitment domain-containing 4,and absent in melanoma 2,as well as the alterations in inflammatory genes(interleukin-1β,interleukin-18,inducible nitric oxide synthase,nuclear factor-kappa B,monocyte chemoattractant protein-1,and C–X3–C motif chemokine ligand 1)and miRNAs(miR-21a-5p,miR-146a-5p,and miR-141-5p)induced by binge-like ethanol treatment in adolescent *** analysis further revealed the involvement of miR-21a-5p and miR-146a-5p with inflammatory target genes and NOD-like receptor signaling *** together,these findings provide novel evidence of the therapeutic potential of MSC-derived EVs to ameliorate the hippocampal neuroinflammatory response associated with NlRP3 inflammasome activation induced by binge drinking in adolescence.

关键词： adolescence binge-like ethanol treatment extracellular vesicles hippocampus mesenchymal stem cells neuroinflammation NOD-,lRR-and pyrin domain-containing protein 3(NlRP3)

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Hölder,Sobolev,weak-type and BMO estimates in mixed-norm with weights for parabolic equations

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Science China Mathematics 2021年第1期64卷 129-154页

作者： Pablo Raúl Stinga josé l.Torrea Department of Mathematics Iowa State UniversityAmesIA50011USA Departamento de Matemáticas Universidad Autónoma de MadridMadrid28049Spain

We prove weighted mixed-norm lqt(W2,px)and lqt(C2,αx)estimates for 10,x∈Rn.x∈Rn,The coefficients a(t)=(aij(t))are just bounded,measurable,symmetric and uniformly ***,we show strong,weak type and BMO-Sobolev estimat... 详细信息

We prove weighted mixed-norm lqt(W2,px)and lqt(C2,αx)estimates for 1l∞t(lpx)−BMOt(W2,px)and l∞t(Cαx)−BMOt(C2,xx),and *** formulas for derivatives,for the solutions u=u(t,x)to parabolic equations of the form∂tu−aij(t)∂iju+u=f,t∈,x∈n and for the Cauchy problem{∂tv−aij(t)∂ijv+v=fv(0,x)forfort>0,x∈Rn.x∈Rn,The coefficients a(t)=(aij(t))are just bounded,measurable,symmetric and uniformly ***,we show strong,weak type and BMO-Sobolev estimates with parabolic Muckenhoupt *** is quite remarkable that most of our results are new even for the classical heat equation∂tu−Δu+u=f.

关键词： Calderón-Zygmund parabolic singular integrals weak type and BMO estimates representation formulas parabolic equations mixed-norm Sobolev and Schauder estimates

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The future of adjuvant therapy in ampullary cancer: should we offer it to our patients?

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Hepatobiliary Surgery and Nutrition 2020年第3期9卷 368-370页

作者： Sri Harsha tella Amit Mahipal Department of Internal Medicine University of South Carolina School of MedicineColumbiaSCUSA Department of Medical Oncology Mayo ClinicRochesterMNUSA

Ampullary carcinoma is a relatively rare and heterogenous neoplasm accounting for 0.2%of all gastrointestinal tract malignancies.

关键词： adjuvant patients neoplasm

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Policy Iteration Algorithms for Zero-Sum Stochastic Differential Games with long-Run Average Payoff Criteria

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Journal of the Operations Research Society of China 2014年第4期2卷 395-421页

作者： joséDaniel lópez-Barrientos Faculty of Actuarial Sciences Universidad Ana´huacMe´xico NorteHuixquilucanMexico

This paper studies the policy iteration algorithm(PIA)for zero-sum stochastic differential games with the basic long-run average criterion,as well as with its more selective version,the so-called bias *** system is assumed to be a nondegenerate *** use lyapunov-like stability conditions that ensure the existence and boundedness of the solution to certain Poisson *** also ensure the convergence of a sequence of such solutions,of the corresponding sequence of policies,and,ultimately,of the PIA.

关键词： Ergodic payoff criterion Zero-sum stochastic differential games Policy iteration algorithm Nondegenerate diffusions Poisson equation Schäl convergence Bias game

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Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3217-3218页

作者： laura Huggon Emma l.Clayton UK Dementia Research Institute at King’s College london LondonUK Department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T D)and amyo t rophic lateral sclerosis(AlS)are neurodegenerative diseases with significant overlapping *** these neurodegenerative diseases affect different neuronal populations(with FTD affecting neurons of the frontal and temporal lobes,and AlS affecting upper and lower motor neurons),these two diseases are complexly *** and AlS exist on a disease spectrum,with shared genetic causes,clinical presentations,and pathologies.

关键词： diseases amyotrophic sclerosis

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Population structure and range expansion:the case of the invasive gastropod Cyclope neritea in northwest Iberian Peninsula

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Integrative Zoology 2012年第3期7卷 286-298页

作者： lucía COUCEIRO lúa lÓPEZ joséMiguel RUIZ Rodolfo BARREIRO Department of Ecology College of ScienceUniversity of A CoruñaA CoruñaSpain

Biotic invasions have a reputation for unpredictable ***,we report how slight changes in human activity responsible for the introduction and range expansion of a non-native mollusk have led to detectable differences in the genetics of the *** neritea is a non-predatory gastropod introduced to 2 areas of the European Atlantic:the northwest Iberian Peninsula(NWIP)and the French Atlantic coast(FAC).Shellfish seabed farming is intense in both areas but focuses on different commercial *** mitochondrial gene sequences,the lower genetic diversity recorded along the NWIP suggests a more homogeneous range of source populations than in the *** FAC,genetic diversity and haplotype composition in the NWIP correlate with the date of first occurrence of *** at each site rather than with geographical *** this pattern evokes the genetic signature expected under a serial-founder colonization model from a single initial enclave,a comparison with samples from potential source populations suggests that the NWIP probably experienced several independent *** jump dispersal pattern of *** in the NWIP,together with the observation that populations established in the same year are genetically undifferentiated,point to human transport as the most plausible explanation for the current range *** evidence for human-mediated dispersal,*** managed to develop a seemingly non-random genetic pattern in the *** is suggested that caution must be exerted when interpreting genetic patterns in invaders.

关键词： alien species Cyclope neritea cytochrome oxidase I genetic geographic pattern population structure

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Carbon Dioxide/Methane Separation by Adsorption on Sepiolite

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Journal of Natural Gas Chemistry 2007年第3期16卷 235-243页

作者： josé A.Delgado María A.Uguina josé l.Sotelo Beatriz Ruíz Marcio Rosário Department of Chemical Engineering Universidad Complutense de Madrid28040Madrid.Spain

In this work, the use of sepiolite for the removal of carbon dioxide from a carbon dioxide/methane mixture by a pressure swing adsorption （PSA） process has been researched. Adsorption equilibrium and kinetics have been measured in a fixed-bed, and the adsorption equilibrium parameters of carbon dioxide and methane on sepiolite have been obtained. A model based on the lDF approximation has been employed to simulate the fixed-bed kinetics, using the langmuir equation to describe the adsorption equilibrium isotherm. The functioning of a PSA cycle for separating carbon dioxide/methane mixtures using sepiolite as adsorbent has also been studied. The experimental results were compared with the ones predicted by the model adapted to a PSA system. Methane with purity higher than 97% can be obtained from feeds containing carbon dioxide with concentrations ranging from 34% to 56% with the proposed PSA cycle. These results suggest that sepiolite is an adsorbent with good properties for its employment in a PSA cycle for carbon dioxide removal from landfill gases.

关键词： carbon dioxide methane sepiolite adsorption fixed-bed pressure swing adsorption

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