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Deforestation and fragmentation trends of seasonal dry tropical forest in Ecuador: impact on conservation

Forest Ecosystems 2021年第3期8卷 615-627页

作者： Carlos A.Rivas joséGuerrero-Casado Rafael M.Navarro-Cerillo Instituto de Ciencias Básicas Universidad Técnica de ManabíPortoviejoManabíEcuador Department of Forest Engineering Laboratory of DendrochronologySilviculture and Global Change–DendrodatLab–ERSAFUniversity of CordobaCampus de RabanalesCrta.IVkm.396E-14071 CordobaSpain Departamento de Medicina Veterinaria Facultad de Ciencias VeterinariasUniversidad Técnica de ManabíPortoviejoManabíEcuador Department of Zoology University of CordobaCampus de Rabanales14071 CordobaSpain

Background:Fragmentation and deforestation are one of the greatest threats to forests,and these processes are of even more concern in the tropics,where the seasonal dry forest is possibly one of the most threatened ecosystems with the least remaining surface area.Methods:The deforestation and fragmentation patterns that had occurred in Ecuadorian seasonal dry forests between 1990 and 2018 were verified,while geographic information systems and land cover shapes provided by the Ecuadorian Ministry of the Environment were employed to classify and evaluate three types of seasonal dry forests:deciduous,semi-deciduous,and transition.The study area was tessellated into 10 km2 hexagons,in which six fragmentation parameters were measured:number of patches,mean patch size,median patch size,total edge,edge density and reticular fragmentation index(RFI).The RFI was also measured both outside and inside protected natural areas(unprotected,national protected areas and protected forest).Moreover,the areas with the best and worst conservation status,connectivity and risk of disappearance values were identified by means of a Getis-Ord Gi*statistical analysis.Results:The deforestation of seasonal dry forests affected 27.04%of the original surface area still remaining in 1990,with an annual deforestation rate of−1.12%between 1990 and 2018.The RFI has increased by 11.61%as a result of the fact that small fragments of forest have tended to disappear,while the large fragments have been fragmented into smaller ones.The semi-deciduous forest had the highest levels of fragmentation in 2018.The three categories of protection had significantly different levels of fragmentation,with lower RFI values in national protected areas and greater values in protected forests.Conclusions:The seasonal dry forest is fragmenting,deforesting and disappearing in some areas.An increased protection and conservation of the Ecuadorian seasonal dry forest is,therefore,necessary owing to the fact that not all protection measures have been effective.

关键词： Deciduous forest Semi-deciduous forest Remnant forest Patch isolation Habitat loss Protected areas

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用氢氧化铝处理浮选循环水同时脱除钙离子和硫酸根离子

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Transactions of Nonferrous Metals Society of China 2022年第7期32卷 2379-2390页

作者： Ángel Daniel guerrero-FLORES Martha Araceli ELIZONDO-ÁLVAREZ joséManuel FLORES-ÁLVAREZ Alejandro URIBE-SALAS Department of Metallurgical Engineering CINVESTAV-IPNUnidad Saltillo25900Ramos ArizpeCoahuilaMéxico Department of Materials Unidad Académica de Ingeniería IUniversidad Autónoma de Zacatecas“Francisco García Salinas”ZacatecasZacatecasMéxico Facultad de Ciencias Químicas Universidad de ColimaCoquimatlánColimaMéxico

由于环境政策和经济因素,复杂硫化物矿的一些浮选作业用水循环使用,导致某些离子的浓度逐渐升高,影响到相关矿物的浮选。在此背景下,对含有高浓度钙和硫酸盐离子的合成溶液的处理进行实验研究和热力学分析。重点评估两种铝化合物对于Ca^... 详细信息

由于环境政策和经济因素,复杂硫化物矿的一些浮选作业用水循环使用,导致某些离子的浓度逐渐升高,影响到相关矿物的浮选。在此背景下,对含有高浓度钙和硫酸盐离子的合成溶液的处理进行实验研究和热力学分析。重点评估两种铝化合物对于Ca^(2+)和SO_(4)^(2-)以钙矾石形式析出过程的作用。结果发现,非晶态氢氧化铝比晶态氢氧化铝更为有效,可脱除高达83%的钙和91%的硫酸盐。对所得固体样品的XRD分析表明,因为吸收了大气中的二氧化碳,主要反应产物为钙矾石,伴随着少量的方解石。化学处理后的最终溶液中残留钙和硫酸盐的浓度低于200 mg/L。动力学研究发现,钙脱除过程对于钙浓度为二级反应,表观活化能为53.48 kJ/mol,表明钙矾石析出过程可能受化学反应控制。

关键词：钙矾石离子去除氢氧化铝钙硫酸盐

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COVID‑19 and tourism sector stock price in Spain:medium‑term relationship through dynamic regression models

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Financial Innovation 2023年第1期9卷 257-280页

作者： Isabel Carrillo‑Hidalgo Juan Ignacio Pulido‑Fernández joséLuis Durán‑Román Jairo casado‑Montilla Laboratory of Analysis and Innovation in Tourism University of JaénParaje Las Lagunillas S/ND3‑13423071 JaénSpain Laboratory of Analysis and Innovation in Tourism University of JaénParaje Las Lagunillas S/ND3‑27323071 JaénSpain Laboratory of Analysis and Innovation in Tourism University of JaénParaje Las Lagunillas S/ND3‑21723071 JaénSpain

The global pandemic,coronavirus disease 2019(COVID-19),has significantly affected tourism,especially in Spain,as it was among the first countries to be affected by the pandemic and is among the world’s biggest tourist destinations.Stock market values are responding to the evolution of the pandemic,especially in the case of tourist companies.Therefore,being able to quantify this relationship allows us to predict the effect of the pandemic on shares in the tourism sector,thereby improving the response to the crisis by policymakers and investors.Accordingly,a dynamic regression model was developed to predict the behavior of shares in the Spanish tourism sector according to the evolution of the COVID-19 pandemic in the medium term.It has been confirmed that both the number of deaths and cases are good predictors of abnormal stock prices in the tourism sector.

关键词： COVID-19 Stock exchange Tourism stock Dynamic regression models Spain

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Trabectedin therapy as an emerging treatment strategy for recurrent platinum-sensitive ovarian cancer

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Chinese Journal of Cancer 2015年第1期34卷 41-49页

作者： josé Antonio López-guerrero Ignacio Romero Andrés Poveda Laboratory of Molecular Biology Fundación Instituto Valenciano de Oncología Clinical Area of Gynecological Cancer Fundación Instituto Valenciano de Oncología

Epithelial ovarian cancer(OC) is a common gynecologic malignancy in women. The standard treatment for OC is maximal cytoreductive surgical debulking followed by platinum-based chemotherapy. Despite the high response rate to primary therapy, approximately 85% of patients will develop recurrent ovarian cancer(ROC). This review identifies the clinical use of trabectedin in the treatment algorithm for ROC, with specific emphasis on platinum-sensitive ROC, for which trabectedin in combination with pegylated liposomal doxorubicin has been approved as a treatment protocol. The main mechanisms of action of trabectedin at the cellular level and in the tumor microenvironment is also discussed as bases for identifying biomarkers for selecting patients who may largely benefit from trabectedin-based therapies.

关键词：治疗方案卵巢癌敏感复发铂疗法恶性肿瘤聚乙二醇化

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Simultaneous removal of calcium and sulfate ions from flotation recycling waters by treatment with aluminum hydroxide

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Transactions of Nonferrous Metals Society of China 2022年

作者： ángel Daniel guerrero-FLORES Martha Araceli Elizondo-álvarez josé Manuel FLORES-áLVAREZ Alejandro URIBE-SALAS Department of Metallurgical Engineering， CINVESTAV-IPN， Unidad Saltillo Department of Materials， Unidad Académica de Ingeniería I， Universidad Autónoma de Zacatecas "Francisco García Salinas"，Zacatecas Facultad de Ciencias Químicas， Universidad de Colima

Due to environmental policies and economic reasons， the water used in some flotation operations of complex sulfide ores is recirculated causing the ion concentration of some species to increase over time， affecting the flotation of the minerals of interest. In the above context， this work presents an experimental and thermodynamic analysis of the treatment of synthetic solutions with a high content of calcium and sulfate ions. The study focused on evaluating the use of two aluminum compounds for the precipitation of Ca;and SO;in the form of ettringite. The amorphous aluminum hydroxide was found to be more efficient than the crystalline one， giving rise to 83% calcium and 91% sulfate removals. The XRD analysis of the solids obtained showed to be ettringite the main reaction product， accompanied by small amounts of calcite， due to the absorption of atmospheric carbon dioxide. The final solution after the chemical treatment showed residual calcium and sulfate concentrations below 200 mg/L. Finally， the kinetics of calcium removal appeared to correspond to a second order reaction with respect to calcium concentration， with an apparent activation energy of 53.5 kJ/mol， which may suggest that the ettringite precipitation process is governed by the chemical reaction.

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Experimentally realizing efficient quantum control with reinforcement learning

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Science China(Physics,Mechanics & Astronomy) 2022年第5期65卷 13-20页

作者： Ming-Zhong Ai Yongcheng Ding Yue Ban joséDMartín-guerrero Jorge Casanova Jin-Ming Cui Yun-Feng Huang Xi Chen Chuan-Feng Li Guang-Can Guo CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Center For Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China International Center of Quantum Artifcial Intelligence for Science and Technology(Qu Artist)and Department of Physics Shanghai UniversityShanghai 200444China Department of Physical Chemistry University of the Basque Country UPV/EHUBilbao 48080Spai School of Materials Science and Engineering Shanghai UniversityShanghai 200444China IDAL Electronic Engineering DepartmentUniversity of ValenciaValencia 46100Spain IKERBASQUE Basque Foundation for ScienceBilbao 48009Spain

We experimentally investigate deep reinforcement learning(DRL)as an artificial intelligence approach to control a quantum system.We verify that DRL explores fast and robust digital quantum controls with operation time analytically hinted by shortcuts to adiabaticity.In particular,the protocol’s robustness against both over-rotations and off-resonance errors can still be achieved simultaneously without any priori input.For the thorough comparison,we choose the task as single-qubit flipping,in which various analytical methods are well-developed as the benchmark,ensuring their feasibility in the quantum system as well.Consequently,a gate operation is demonstrated on a trapped^(171) Yb^(+)ion,significantly outperforming analytical pulses in the gate time and energy cost with hybrid robustness,as well as the fidelity after repetitive operations under time-varying stochastic errors.Our experiments reveal a framework of computer-inspired quantum control,which can be extended to other complicated tasks without loss of generality.

关键词： quantum control reinforcement learning trapped ion quantum computing noise robustness

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An Evolutionary Approach to the Delineation of Functional Areas Based on Travel-to-work Flows

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International Journal of Automation and computing 2008年第1期5卷 10-21页

作者： Francisco Flórez-Revuelta joséManuel casado-Díaz Lucas Martínez-Bernabeu Department of Computing Technology University of AlicanteP.O.Box 99E-03080AlicanteSpain Institute of International Economics University of AlicanteP.O.Box 99F-03080AlicanteSpain

This paper presents a new approach to the delineation of local labor markets based on evolutionary computation. The aim of the exercise is the division of a given territory into functional regions based on travel-to-work flows. Such regions are defined so that a high degree of inter-regional separation and of intra-regional integration in both cases in terms of commuting flows is guaranteed. Additional requirements include the absence of overlap between delineated regions and the exhaustive coverage of the whole territory. The procedure is based on the maximization of a fitness function that measures aggregate intra-region interaction under constraints of inter-region separation and minimum size. In the experimentation stage, two variations of the fitness function are used, and the process is also applied as a final stage for the optimization of the results from one of the most successful existing methods, which are used by the British authorities for the delineation of travel-to-work areas （TTWAs）. The empirical exercise is conducted using real data for a sufficiently large territory that is considered to be representative given the density and variety of travel-to-work patterns that it embraces. The paper includes the quantitative comparison with alternative traditional methods, the assessment of the performance of the set of operators which has been specifically designed to handle the regionalization problem and the evaluation of the convergence process. The robustness of the solutions, something crucial in a research and policy-making context, is also discussed in the paper.

关键词： Evolutionary computation regional science economics optimization methods

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Taurine as a possible therapy for immunosenescence and inflammaging

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Cellular & Molecular Immunology 2024年第1期21卷 3-5页

作者： joséM.Izquierdo Centro de Biología Molecular Severo Ochoa(CBMSO).Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid(CSIC/UAM)C/Nicolás Cabrera 1Campus de Cantoblanco28049MadridSpain

In their recent Science article,Singh et al.identified taurine as an endogenously produced anti-inflammatory,anti-immunosenescence,and anti-aging molecule.The authors also show that restoring taurine to its“youthful... 详细信息

关键词： Taurine inflam

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Glycoprotein biomarkers for the detection of pancreatic ductal adenocarcinoma

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World Journal of Gastroenterology 2018年第24期24卷 2537-2554页

作者： Esther Llop Pedro E guerrero AdriàDuran Sílvia Barrabés Anna Massaguer María joséFerri Maite Albiol-Quer Rafael de Llorens Rosa Peracaula Department of Biology Biochemistry and Molecular Biology UnitUniversity of GironaGirona 17003Spain Biomedical Research Institute of Girona(IdIBGi).Parc Hospitalari Martíi Julià-Edifici M2 Salt 17190Spain Clinic Laboratory University Hospital Dr Josep TruetaGirona 17007Spain Department of Surgery Hepato-biliary and Pancreatic Surgery UnitUniversity Hospital Dr Josep TruetaGirona 17007Spain

Pancreatic cancer(Pa C) shows a clear tendency to increase in the next years and therefore represents an important health and social challenge. Currently, there is an important need to find biomarkers for PaC early detection because the existing ones are not useful for that purpose. Recent studies have indicated that there is a large window of time for PaC early detection, which opens the possibility to find early biomarkers that could greatly improve the dismal prognosis of this tumor. The present manuscript reviews the state of the art of the existing PaC biomarkers. It focuses on the anomalous glycosylation process and its role in PaC. Glycan structures of glycoconjugates such as glycoproteins are modified in tumors and these modifications can be detected in biological fluids of the cancer patients. Several studies have found serum glycoproteins with altered glycan chains in PaC patients, but they have not shown enough specificity for PaC. To find more specific cancer glycoproteins we propose to analyze the glycan moieties of a battery of glycoproteins that have been reported to increase in PaC tissues and that can also be found in serum. The combination of these new candidate glycoproteins with their aberrant glycosylation together with the existing biomarkers could result in a panel, which would expect to give better results as a new tool for early diagnosis of PaC and to monitor the disease.

关键词： Pancreatic cancer Aberrant glycosylation Glycoproteins Biomarkers Diagnosis

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Mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： joséM.Izquierdo Centro de Biología Molecular Severo Ochoa(CBM) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

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