This paper presents a methodology for analytical calculation and computational simulation using the finite element method for piezoresistive graphite sensor element on flexible polymer substrate,A4 *** computer simula...
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This paper presents a methodology for analytical calculation and computational simulation using the finite element method for piezoresistive graphite sensor element on flexible polymer substrate,A4 *** computer simulation aims to find the region of greatest mechanical tension and deflection of the circular diaphragm set in the circumference *** steps for simulation are geometry definition,mesh generation,inclusion of material physical properties and simulation *** mathematical modeling of maximum mechanical stress and deflection is described analytically and *** analytical calculations were compared with the computer simulation and presented a relative percentage error of 3.38%for the maximum *** results show that the piezoresistor should be positioned at the edges of the circular diaphragm to take advantage of maximum mechanical stress by defining the best location for graphite film deposition for sensor device designs and fabrications.
Background: It has been published that hypertension (HT)-must be taken into a ccount when using NT-proBNP, but left ventricular (LV) hypertrophy without HT c ould be a cause of NT-proBNP elevation. In a population stu...
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Background: It has been published that hypertension (HT)-must be taken into a ccount when using NT-proBNP, but left ventricular (LV) hypertrophy without HT c ould be a cause of NT-proBNP elevation. In a population study we compared NT-p roBNP in subjects with hypertrophy, with and without diagnosis of HT. methods: W e studied 215 subjects from a random sample of 432 people who had declared to su ffer from dyspnea. These 432 subjects were referred to their hospital where bloo d samples were taken, an echo-Doppler study was performed and a specific questi onnaire was completed. We got a positive answer from 215, and 52 (24%) have LV hypertrophy. Results: When we compared NT-proBNP in non-hypertrophic populatio n, 148±286 pg/ml, with NT-proBNP in LV hypertrophic population, 202±209 pg/ml , we found Pmpared NT-proBNP (199 ±201 pg/ml) in normotensive subjects (LV mass index 170±70 g/m2, Vp 50±18 cm/ s, LVEF 62±8) with NT-proBNP (205±220 pg/ml) in subjects with diagnosis of HT (LVmass index 169±37 g/m2, Vp 55±20 cm/s, LVEF 64±10), we found NS. Conclusi ons: This population study shows that NT-proBNP is elevated in patients with LV hypertrophy with or without HT. In LV hypertrophy the presence of HT does not i nfluence the peptide levels significantly.
Introduction. megalencephalic leukoencephalopathy with subcortical cysts is a rare disease with autosomal recessive inheritance. materials and methods. Two br others born from a consanguineous marriage, presenting wit...
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Introduction. megalencephalic leukoencephalopathy with subcortical cysts is a rare disease with autosomal recessive inheritance. materials and methods. Two br others born from a consanguineous marriage, presenting with the phenotype of the disease, their parents, brothers and sisters were examined. magnetic resonance imaging of the brain was performed for the two patients. Sequence analysis of mL C1 (GenBank mRNA accession no. Nm 015166) was performed for the patients using i ntronic primers. PCR restriction fragment length polymorphism analysis was done in patients, their parents and in 100 Lebanese controls in order to exclude gene ***. The clinical features were characteristic of the disease, consisting of an early-onset macrocephaly followed by slowly progressive ataxia , pyramidal tract involvement and epileptic seizures. In one patient, the clinic al manifestations were aggravated by a trivial brain trauma. In his brother and in one female cousin, a status epilepticus was precipitated by a febrile syndrom e. The diffuse cerebral white matter lesions and the subcortical temporo-polar and frontal cysts, best seen on mRI,allowed making the *** genet ics revealed a new mutation involving the mLC1 gene (263G→T, exon 3). As a cons equence, it affects the second transmembrane domain predict (G88V) of the mLC pr otein (protein sequence NP 055981). The mutation was confirmed by PCR restrictio n fragment length polymorphism analysis. Conclusion. megalencephalic leucoenceph alopathy with subcortical cysts may be individualized on clinical and radiologic al basis and confirmed by molecular genetics. In this Lebanese family, a new mut ation of the mLC1 gene is reported.
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