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Declining metabolic scaling parallels an ontogenetic change from elongate to deep-bodied shapes in juvenile Brown trout

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Current Zoology 2023年第3期69卷 294-303页

作者： jorge-ruben sanchez-gonzalez Alfredo G.Nicieza Department of Organisms andSystems Biology University of Oviedo33006O OviedoSpain Biodiversity Research Institute(IMIB) University of Oviedo-Principality of Asturias-CSIC33600 MieresSpain Department of Animal Science-Wildlife Section University of Lleida25006 LleidaSpain

Body shape and metabolic rate can be important determinants of animal performance,yet often their effects on influential traits are evaluated in a non-integrated *** creates an important gap because the integration between shape and metabolism may be crucial to evaluate metabolic scaling ***,we measured standard metabolic rate in 1-and 2-years old juvenile brown trout Salmo trutta,and used a geometric morphometrics approach to extricate the effects of ontogeny and size on the link between shape and metabolic *** evidenced near-isometric ontogenetic scaling of metabolic rate with size,but also a biphasic pattern driven by a significant change in metabolic scaling,from positive to negative ***,the change in metabolic allometry parallels an ontogenetic change from elongate to deep-bodied *** is consistent with the dynamic energy budget(DEB)and surface area(SA)theories,but not with the resource transport network theory which predicts increasing allometric exponents for trends towards more robust,three-dimensional *** addition,we found a relationship between body shape and size independent metabolic rate,with a positive correlation between robustness and metabolic rate,which fits well within the view of Pace-of-Life Syndromes(POLS).Finally,our results align with previous studies that question the universality of metabolic scaling exponents and propose other mechanistic models explaining the diversity of metabolic scaling relationships or emphasizing the potential contribution of ecological factors.

关键词： biphasic allometric scaling metabolic rate ontogenetic allometry shape surface-area trout

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Decoding complexity: the need to enhance precision and streamline spatial understanding in neuroscience

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Neural Regeneration Research 2025年第3期20卷 801-802页

作者： Sameehan Mahajani Armita Salahi Brenda gonzalez Charlotte Nelson Frank Hsiung Biology&Applications Division NodexusSan JoseCAUSA

Neuroscience is the ultimate frontier in our quest for a comprehensive understanding of human behavior. Since its launch in 2009, the Human Connectome Project has emerged as a pioneering force, making heroic strides i... 详细信息

关键词： behavior frontier dating

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Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

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Neural Regeneration Research 2025年第9期20卷 2454-2463页

作者： Victoria Jiménez Carretero IrisÁlvarez-Merz jorge Hernández-Campano Sergei A.Kirov Jesús M.Hernández-Guijo Department of Pharmacology and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute for Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of Neurobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neuroscience and Regenerative Medicine&Department of Neurosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is ***,the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely *** release of amino acids by necrotic cells in the ischemic core may contribute to the expansion of the *** findings indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia became irreversible when exposed to a mixture of just four non-excitatory amino acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino acids induce swelling in the somas of neurons and astrocytes during hypoxia,along with permanent dendritic damage mediated by N-methyl-D-aspartate *** N-methyl-D-aspartate receptors prevented neuronal damage in the presence of these amino acids during *** is likely that astroglial swelling caused by the accumulation of these amino acids via the alanine-serine-cysteine transporter 2 exchanger and system N transporters activates volume-regulated anion channels,leading to the release of excitotoxins and subsequent neuronal damage through N-methyl-D-aspartate receptor ***,previously unrecognized mechanisms involving non-excitatory amino acids may contribute to the progression and expansion of brain injury in neurological emergencies such as stroke and traumatic brain *** these pathways co uld highlight new therapeutic targets to mitigate brain injury.

关键词： cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids stroke synaptic transmission

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Computing the topology of an arrangement of implicitly defined real algebraic plane curves~§

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第12期9卷 1685-1693页

作者： jorge CARAVANTES Laureano gonzalez-VEGA Department of Mathematics Statistics and ComputationUniversity of CantabriaSantander39005CantabriaSpain

We introduce a new algebraic approach dealing with the problem of computing the topology of an arrangement of a finite set of real algebraic plane curves presented implicitly. The main achievement of the presented method is a complete avoidance of irrational numbers that appear when using the sweeping method in the classical way for solving the problem at hand. Therefore, it is worth mentioning that the efficiency of the proposed method is only assured for low-degree curves.

关键词： Topology computation Real plane curves Sweeping method

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A survey of static and dynamic potential games

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Science China Mathematics 2016年第11期59卷 2075-2102页

作者： gonzalez-sanchez David HERNANDEZ-LERMA Onesimo Consejo Nacional de Ciencia y Tecnología Universidad de Sonora Hermosillo 83000 Mexico Mathematics Department Centro de Investigación y de Estudios Avanzados del Instituto Politecnico National Mexico City 07000 Mexico

Potential games are noncooperative games for which there exist auxiliary functions, called potentials,such that the maximizers of the potential are also Nash equilibria of the corresponding game. Some properties of Nash equilibria, such as existence or stability, can be derived from the potential, whenever it exists. We survey different classes of potential games in the static and dynamic cases, with a finite number of players, as well as in population games where a continuum of players is allowed. Likewise, theoretical concepts and applications are discussed by means of illustrative examples.

关键词： noncooperative games potential games Nash equilibrium dynamic games Markov games differential games population games

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From Network Functions to NetApps: The 5GASP Methodology

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Computers, Materials & Continua 2022年第5期71卷 4115-4134页

作者： jorge Gallego-Madrid Ramon sanchez-Iborra Antonio Skarmeta University of Murcia Murcia30100Spain University Center of Defense General Air Force AcademySan Javier30720Spain

As the 5G ecosystem continues its consolidation,the testing and validation of the innovations achieved by integrators and verticals service providers is of preponderant *** this line,5GASP is a European H2020-funded project that aims at easing the idea-to-market process through the creation of an European testbed that is fully automated and self-service,in order to foster rapid development and testing of new and innovative 5G Network Applications(NetApps).The main objective of this paper is to present the 5GASP’s unified methodology to design,develop and onboard NetApps within the scope of different vertical services,letting them use specific 5G ***,we examine the whole 5GASP process in a tutorial fashion by adopting a specific use case focusing on the integration of a virtual On-Board Unit(vOBU)service that permits offloading processing from the attached vehicle and serving data-access *** demonstrated,the presented workflow permits the agile,rigorous,and safe development,testing and certification of NetApps,which will enable valuable in-network services for 5G and beyond infrastructures.

关键词： 5G NetApp 5GASP vOBU

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Winkler Support Model and Nonlinear Boundary Conditions Applied to 3D Elastic Contact Problem Using the Boundary Element Method

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Acta Mechanica Solida Sinica 2019年第2期32卷 230-248页

作者： J.Vallepuga-Espinosa Lidia sanchez-gonzalez Ivan Ubero-Martinez Departamento de Tecnologia Minera Topografiay de EstructurasUniversidad de LeonCampus de Vegazana s/n24071 LeonSpain Departamento de Ingenierias Mecanica Informatica y AeroespacialUniversidad de LeonCampus de Vegazana s/n24071 LeonSpain

This work presents a numerical methodology for modeling the Winkler supports and nonlinear conditions by proposing new boundary conditions. For the boundary conditions of Winkler support model, the surface tractions and the displacements normal to the surface of the solid are unknown, but their relationship is known by means of the ballast coefficient, whereas for nonlinear boundary conditions, the displacements normal to the boundary of the solid are zero in the positive direction but are allowed in the negative direction. In those zones, detachments of nodes might appear, leading to a nonlinearity, because the number of nodes that remain fixed or of the detached ones (under tensile tractions) is unknown. The proposed methodology is applied to the 3D elastic receding contact problem using the boundary element method. The surface t r actions and the displacements of the common int erface bet ween the two solids in contac t under the influence of different supports are calculated as well as the boundary zone of the solid where the new boundary conditions are applied. The problem is solved by a double-iterative met hod, so in the final solut ion, t here are no t r act ions or pene trations between the two solids or at the boundary of the solid where the nonlinear boundary conditions are Simula ted. The effectiveness of the proposed method is verified by examples.

关键词： Boundary element method Elastic contact problem Winkler support model Nonlinear boundary conditions

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Sound Modulation in Singing Katydids Using Ionic Polymer-Metal Composites （IPMCs）

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Journal of Bionic Engineering 2013年第4期10卷 464-468页

作者： Yan Zhou Cheng-Wei Chiu Carlos J. sanchez jorge M. gonzalez Benjamin Epstein David Rhodes S. Bradleigh Vinson Hong Liang Materials Science and Engineering Texas A&M University College Station TX 77843 USA Department of Mechanical Engineering Texas' A&M University College Station TX 77843 USA Department of Entomology Texas A&M University College Station TX77843 USA Department of Plant Science California State University Fresno CA 93740 USA OpCoast LLC Brick NJ08723 USA

Many insect families have evolved to produce and detect complex singing patterns for the purposes of mating, display of dominance, predator escape, and other needs. While the mechanisms of sound production by insects have been thoroughly studied, man-machine exploitation of such mechanisms has remained unreported. We therefore describe a method to modulate the frequency spectrum in the chirp call of a singing insect, Gampsocleis gratiosa （Orthoptera： Tettigoniidae）, a large katydid indigenous to China and commonly known as Guo Guo or Chinese Bush Cricket. The chirp modulation was achieved through the contact of a ribbon of lonic Polymer-Metal Composite （IPMC） against wing of the insect. The IPMC effectively served as an actuator when a small DC voltage was applied to the ribbon＇s faces. By applying a sequential on/off voltage waveform to the IPMC ribbon, the katydid＇s chirp was modulated in a corresponding manner. This configuration can be used as part of a broader application of using singing insects to harness their acoustic power to produce and propagate machine-induced messages into the acoustic environment.

关键词： chirp modulation katydid IPMC

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Intraexaminer repeatability and agreement in stereoacuity measurements made in young adults

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International Journal of Ophthalmology(English edition) 2015年第2期8卷 374-381页

作者： Beatriz Antona Ana Barrio Isabel sanchez Enrique gonzalez Guadalupe gonzalez Department of Optics II (Optometry and Vision) Faculty of Optics and Optometry Complutense University of Madrid

AIM: To determine the repeatability and agreement of stereoacuity measurements made using some of the most widely used clinical tests: Frisby, TNO, Randot and ***: Stereoacuity was measured in two different sessions separated by a time interval of at least 24 h but no longer than 1wk in 74 subjects of mean age 20.6y using the four methods. The study participants were divided into two groups: subjects with normal binocular vision and subjects with abnormal binocular ***: Best repeatability was shown by the Frisby and Titmus [coefficient of repeatability(COR): ±13 and±12s arc respectively] in the subjects with normal binocular vision though a clear ceiling effect was *** the subjects with abnormal binocular vision, best repeatability was shown by the Frisby(COR: ±69s arc)and Randot(COR: ±72s arc). In both groups, the TNO test showed poorest agreement with the other ***:Therepeatabilityofstereoacuitymeasures was low in subjects with poor binocular vision yet fairly good in subjects with normal binocular vision with the exception of the TNO test. The reduced agreement detected between the tests indicates they cannot be used interchangeably.

关键词： stereoacuity repeatability agreement tereopsis

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Machine learning-based zero-touch network and service management:a survey

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Digital Communications and Networks 2022年第2期8卷 105-123页

作者： jorge Gallego-Madrid Ramon sanchez-Iborra Pedro M.Ruiz Antonio F.Skarmeta Department of Information and Communication Engineering University of Murcia30100MurciaSpain Department of Engineering and Applied Techniques University Center of Defense30729San Javier Air Force BaseSpain

The exponential growth of mobile applications and services during the last years has challenged the existing network ***,the arrival of multiple management solutions to cope with this explosion along the end-to-end network chain has increased the complexity in the coordinated orchestration of different segments composing the whole *** Zero-touch Network and Service Management(ZSM)concept has recently emerged to automatically orchestrate and manage network resources while assuring the Quality of Experience(QoE)demanded by *** Learning(ML)is one of the key enabling technologies that many ZSM frameworks are adopting to bring intelligent decision making to the network management *** paper presents a comprehensive survey of the state-of-the-art application of ML-based techniques to improve ZSM *** this end,the main related standardization activities and the aligned international projects and research efforts are deeply *** this dissection,the skyrocketing growth of the ZSM paradigm can be ***,different standardization bodies have already designed reference architectures to set the foundations of novel automatic network management functions and resource *** with these advances,diverse ML techniques are being currently exploited to build further ZSM developments in different aspects,including multi-tenancy management,traffic monitoring,and architecture coordination,among ***,different challenges,such as the complexity,scalability,and security of ML mechanisms,are also identified,and future research guidelines are provided to accomplish a firm development of the ZSM ecosystem.

关键词： Zero-touch network and service management(ZSM) Next generation networks(NGN) Artificial intelligence(AI) Machine learning(ML)

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