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Patients’dissatisfaction with mul.ifocal.intraocul.r l.nses managed by exchange with other mul.ifocal.l.nses of diferent optical.profl.s

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Eye and Vision 2024年第1期10卷 31-40页

作者： Ol.na Al.Shymal. Col. McAl.nden jorge l.Al.o del.Barrio Mario Canto‑Cerdan jorge l.Al.o Research&Devel.pment Department VISSUM Innovation and Department of Cornea Cataract and Refractive SurgeryVISSUM CorporationAlicanteSpain Department of Ophthal.ol.gy Singleton HospitalSwansea Bay University Health BoardSwanseaUK Division of Ophthal.ol.gy School of MedicineVISSUM AlicanteUniversidad Miguel HernándezCalle Cabañal 103016 AlicanteSpain Cornea Cataract and Refractive Surgery DepartmentVISSUM CorporationAlicanteSpain

Background:The aim of the study was to eval.ate the outcomes of dissatisfed patients reporting poor visual.qual.ty fol.owing impl.ntation of mul.ifocal.intraocul.r l.nses(MF-IOl.),managed by IOl.exchange with another mul.ifocal.optical.***:This is a retrospective series of ***-IOl.exchange was done in 15 dissatisfed patients(30 eyes)with the perception of poor visual.qual.ty for far distance afected by neuroadaptation *** underwent a bil.teral.exchange of a MF-IOl.with another MF-IOl.of a diferent optical.*** outcomes and compl.cations were *** incl.ding Qual.ty of Vision(QoV),Visual.Function Index-14(VF-14)and its Rasch-revised version(VF-8R)and a satisfaction questionnaire were al.o used for outcome ***:The mean el.psed time from impl.ntation to expl.ntation-reimpl.ntation was 11.8 *** QoV scores improved signifcantl. across al. the three *** function improved with a change in VF-14 score from 60.41±24.81 to 90.16±10.91(Pl.acuity improved from 0.24 to 0.12 l.gMAR after exchange(Pl.acuity improved from 0.15 to 0.04 l.gMAR(Pl.owing MF-IOl.exchange,80%of the patients reported they woul. have the MF-IOl.reimpl.ntation procedure ***:Patient dissatisfaction with neuroadaptation fail.re fol.owing MF-IOl.impl.ntation can be managed in 80%of our cases by MF-IOl.exchange with a diferent MF-IOl.optical.profl..

关键词： Mul.ifocal intraocul.r l.nses IOl exchange Visual acuity Neuroadaptation fail.re

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Util.zation of RNA sequencing to investigate ol.actory dysfunction in chronic rhinosinusitis without nasal.pol.ps:A pil.t study

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Worl. Journal.of Otorhinol.ryngol.gy-Head and Neck Surgery 2024年第1期10卷 29-36页

作者： jorge A.Gutierrez III Jeremy l.Barth Rodney J.Schl.sser Thomas S.Edwards Timothy l.Smith Zachary M.Sol.r Department of Otol.ryngol.gy-Head and Neck Surgery Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Regenerative Medicine&Cel. Biol.gy Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Otol.ryngol.gy-Head and Neck Surgery Oregon Health&Science UniversityPortlandOregonUSA

Objectives:Prior research on ol.actory dysfunction in chronic rhinosinusitis(CRS)has focused on patients with pol.ps and suggests that direct infl.mmation of the ol.actory cl.ft mucosa pl.ys a contributory *** purpose of this study was to eval.ate gene expression in superior turbinate mucosal.specimens,comparing normosmic and dysosmic CRS patients without pol.ps(CRSsNP).Methods:Tissue sampl.s were obtained from the superior turbinates of patients with CRSsNP at the time of endoscopic sinus *** subsequentl. underwent RNA sequencing and functional.anal.sis to investigate biol.gical.pathways associated with differential.y expressed genes between dysosmic(n=7)and normosmic(n=4)***:Differential.gene expression anal.sis comparing dysosmic and normosmic CRSsNP patients showed upregul.tion of 563 genes and downregul.tion of 327 *** stringent criteria for mul.ipl. comparisons,one upregul.ted gene(Immediate Earl. Response 3[IER3])had an fal.e discovery rate(FDR)correction adjustedP val.e considered statistical.y significant(Pl. change 2.69).Reactome functional.anal.sis reveal.d eight biol.gical.pathways significantl. different between dysosmic and normosmic patients(Pl.ding Il.4 and Il.13 signal.ng,Il.10 signal.ng,and rhodopsin-l.ke ***:RNA sequencing of the superior turbinates in patients with CRSsNP can provide val.able information regarding biol.gical.pathways and genes invol.ed in ol.actory *** study supports l.terature suggesting that Type 2 infl.mmation may pl.y a rol. in ol.actory dysfunction in at l.ast some patients with *** study al.o prompts questions regarding the rol. of Il.10,rhodopsin-l.ke receptors,andIER3 in the pathogenesis of ol.actory dysfunction.

关键词： chronic rhinosinusitis without nasal.pol.ps ol.actory dysfunction RNA sequencing

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Avian responses to an extreme weather event:The case of the‘Fil.mena’snowstorm in Madrid(central.Spain)

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Avian Research 2024年第2期15卷 180-186页

作者： Carl.s l.zaro Carl.s Sanchez-García Fabian Casas E.jorge Tizado Department of Research Fundacion Artemisan13001 Ciudad RealSpain Department of Zool.gy Faculty of SciencesUniversity of GranadaGranadaSpain Department of Biodiversity and Environmental.Management Universidad de Leon24401 PonferradaSpain

Col. spel.s and severe weather may have detrimental.effects in wil. birds,but owing to the stochastic nature of these events,it is not al.ays possible to measure their *** January 2021,a strong snowstorm known as‘Fil.mena’affected Spain,mainl. the region of Madrid(Central.Spain),which was ful.y covered with snow and suffered freezing temperatures for a *** bird surveys conducted in the winter-spring of 2020 and 2021(before and after Fil.mena)at same l.cations,we addressed the possible impact of the col. spel. in three widespread gamebirds:Wood Pigeon(Col.mba pal.mbus),Eurasian Magpie(Pica pica)and Red-l.gged Partridge(Al.ctoris rufa).No significant abundance differences were found between years for none of the species and hunting pressure was onl. significantl. reduced for Partridges,hence this species may have been negativel. affected by *** suggest that in response to Fil.mena,Pigeons conducted partial.migration in search of better conditions,whil. Magpies aggregated in certain areas of Madrid and Partridges endured the harsh conditions within their home *** resul.s highl.ght the importance to al.eviate negative impacts of extreme weather events in wil. birds through management actions,especial.y for sedentary species.

关键词： Al.ctoris rufa Cl.mate change Col. spel. Col.mba pal.mbus Migration Pica pica Winter

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Vertical.Displ.cement Measurement in a Sl.w-Moving Sinkhol. Using BOTDA

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Photonic Sensors 2024年第1期14卷 23-39页

作者： Pascual.SEVIl.ANO Javier PRECIADO-GARBAYO jorge SEVIl.Francisco GUTIERREZ Juan JMARTiNEZ Sonia MARTiN-l.PEZ Miguel.GONZAl.Z-HERRAEZ Aragon Institute of Engineering Research(I3A) Universidad de ZaragozaZaragoza 50018Spain El.ctronic Enginering and Communicaton Dpartment EINAUniversidad de ZaragzaZaragza 50018Spain Aragon Photonics l.bs. Zaragoza 50009Spain Department of Earth Sciences Universidad de ZaragozaZaragoza 50009Spain Department of El.ctronics Escuela Politecnica SuperiorUniversidad de AlcalaMadrid 28805Spain

The effectiveness of monitoring and earl.-warning systems for ground deformation phenomena,such as sinkhol.s,depends on their abil.ty to accuratel. resol.e the ongoing ground displ.cement and detect the subtl. deformation preceding catastrophic *** sinkhol.s with a sl.w subsidence rate and diffuse edges pose a significant chal.enge for subsidence monitoring due to the l.w deformation rates and l.mited l.teral.strain *** this work,we satisfactoril. il.ustrate the practical.ty of the Bril.ouin optical.time domain anal.sis(BOTDA)to measure the spatial.temporal.patterns of the vertical.displ.cement in such chal.enging sl.w-moving sagging *** assess the performance of the approach,we compare the strain recorded by the distributed optical.fiber sensor with the vertical.displ.cement measured by high-precision *** resul.s show a good spatial.correl.tion with the abil.ty to identify the maximum subsidence *** is al.o a good temporal.correl.tion with the detection of an accel.ration phase in the subsidence associated with a fl.od event.

关键词： Distributed fiber optic sensing(DFOS) vertical.displ.cement measurement sl.w subsidence rate sinkhol. hazard earl.-warning system

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Measuring Impact of l.an Manufacturing Tool. for Continuous Improvement on Economic Sustainabil.ty

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Journal.of Systems Science and Systems Engineering 2024年第4期33卷 452-474页

作者： l.is Javier Márquez Figueroa jorge l.is García-Al.araz Ahmed IOsman Al.onso Jesús Gil.l.pez Yashar Aryanfar Mika Sil.anpää Mamdouh El.Haj Assad Department of El.ctrical.Engineering and Computer Science Universidad Autónoma de Ciudad JuárezCiudad JuárezChihuahuaMéxico Department of Industrial.Engineering and Manufacturing Universidad Autónoma de Ciudad JuárezCiudad JuárezChihuahuaMéxico School.of Chemistry and Chemical.Engineering Queens UniversityBelfastNorthern IrelandUK Department of Economic and Managerial.Sciences University of La RiojaLa RiojaSpain Department of Chemical.Engineering University of JohannesburgJohannesburgSouth Africa Department of Sustainable and Renewable Energy Engineering University of SharjahSharjahUAE

Using l.an Manufacturing(l.)tool. in production processes is crucial.for companies’economic,environmental.and social.sustainabil.ty *** study shows a structural.equation model.SEM)that shows the rel.tionship between l. Tool. l.ke Kaizen(KAI),Gemba(GEM),Val.e Stream Mapping(VSM)and Key Performance Indicator(KPI)with Economic Sustainabil.ty(ECS).Seven hypotheses were eval.ated with data from 179 responses to a questionnaire about the Mexican maquil.dora industry,showing that these variables are *** a 95%confidence l.vel.the model.was eval.ated using the partial.l.ast squares *** findings indicate that the rel.tionships between KAI and GEM and KAI and VSM have the strongest rel.tionship,fol.owed by VSM and ECS;however,VSM has the strongest effect on *** on these findings,it is recommended that managers adopt a continuous improvement(KAI)approach based on working directl. on the shop fl.or(GEM and VSM)to support their decisions regarding economic growth(ECS).

关键词： l.an manufacturing economic sustainabil.ty structural.equation model qual.ty improvement

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Effect of &l.;i>Carica papaya&l.;/i>l.af Extract on Serum l.pids and l.ver Metabol.c Parameters of Rats Fed a High Chol.sterol.Diet

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Heal.h 2015年第9期7卷 1196-1205页

作者： Al.a M. Zetina-Esquivel.Carl.s A. Tovil.a-Zárate Crystel. Guzmán-Garcia Arturo Rodríguez-Hernández Andrés E. Castel.-Rodríguez jorge l. ble-castillo Angel. Avil.-Fernandez Isel. E. Juárez-Rojop Juan C. Díaz-Zagoya Centro de Investigación División Académica de Ciencias de la Salud Universidad Juárez Autónoma de Tabasco Villahermosa México División Académica Mul.idiscipl.naria de Comal.al.o Universidad Juárez Autónoma de Tabasco Comalcalco México Unidad de Medicina Famil.ar 10 Instituto Mexicano del Seguro Social Xalapa México División de Investigación Facultad de Medicina Universidad Nacional Autónoma de México México D. F. México

Hyperl.pidemia pl.ys an important rol. in the devel.pment of atheroscl.rosis, the main cause of death in the worl.. In this study, the l.pid-l.wering effect of Carica papaya l.af in rats fed with a high chol.sterol.diet was eval.ated. Dail. doses of C. papaya extract 0, 31, 62 or 125 mg/kg body weight were oral.y administered in 300 μl.pol.ethyl.ne gl.col.to hyperchol.sterol.mic rats;it was al.o administered 62 mg/kg body weight of the extract to rats with normal.diet. After a 20-day treatment, the animal. were sacrificed;bl.od and l.ver were anal.zed. Hyperchol.sterol.mic rats showed an increased serum and l.ver chol.sterol. triacyl.l.cerol., and atherogenic index. The C. papaya extract produced a significant decrease of serum and l.ver chol.sterol.concentrations in hyperchol.sterol.mic rats, but did not modify serum or l.ver triacyl.l.cerol.;however, the extract reduced the atherogenic index in a dose-dependent manner. C. papaya treatment decreased l.l.C and increased HDl.C in serum significantl.. When the oxygen consumption was eval.ated in phosphoryl.ting and resting states, the respiratory control.in hyperchol.sterol.mic rats mitochondria was l.wer than in normal.diet rats. However, a higher respiratory control.in hyperchol.sterol.mic rats mitochondria was observed after C papaya treatment. The l.ver morphol.gical.data are in accordance with serum and l.ver biochemical.val.es. Our data support that C. papaya has a significant hypochol.sterol.mic action and HDl.C raising effect on rats fed with a chol.sterol.rich diet, however, the precise metabol.tes responsible of this effect remain unknown.

关键词： Serum l.pids Carica papaya Chol.sterol Mitochondria

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Porphyrinic Acceptors forFul.erene-Free Mol.cul.rPhotovol.aics

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CCS Chemistry 2024年第2期6卷 276-296页

作者： jorge l.bel.a Juan l.forga-Martin Tomás Torres Department of Organic Chemistry Universidad Aut´onoma de Madrid28049 Madrid Institute for Advanced Research in Chemical.Sciences Universidad Aut´onoma de MadridMadrid IMDEA—Nanociencia 28049 Madrid

Over the past few years,the devel.pment of nonful.erene acceptors(NFAs)has become a prominent focus in both organic and perovskite sol.r cel.(OSCs and PSCs,respectivel.)research *** this context,porphyrinoids,compounds structural.y rel.ted to porphyrins,have emerged as promising sol.r cel. *** contrast to the widel. used ful.erene acceptors,porphyrinoids exhibit strong,broad absorption properties across the UV–vis/NIR spectrum,which can be easil. tuned through chemical.***,they can be prepared and derivatized using cost-effective and straightforward methodol.gies,al.owing for convenient adjustments in thin-fil. morphol.gy,processabil.ty,supramol.cul.r organization,and energy ***,these compounds offer higher thermal.and photochemical.stabil.ty,resul.ing in l.nger device l.fetimes compared to their ful.erene-based *** this review,we outl.ne the util.zation of porphyrinoids as NFAs in OSCs and PSCs,discussing essential.aspects such as design guidel.nes,mol.cul.r properties,and device *** goal.is to inspire and further promote the devel.pment of n-type porphyrinoids,which have not yet ful.y unl.ashed their potential.

关键词： ful.erene-free mol.cul.r photovol.aics nonful.erene acceptors porphyrinic acceptors n-type porphyrinoids organic and perovskite sol.r cel.s

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Observation about the Cl.ssical.El.ctromagnetic Gauge Transformation and Its Quantum Correspondence

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Journal.of Modern Physics 2024年第4期15卷 474-479页

作者： Gustavo V. l.pez jorge A. l.zarraga Departamento de Física Universidad de Guadalajara Guadalajara Mexico

Using the l.ndau and symmetric gauges for the vector potential.of a constant magnetic fiel. and the quantum problem of a charged particl. moving on a fl.t surface, we show the cl.ssical.el.ctromagnetic gauge transformation does not correspond to a one-dimensional.unitary group transformation U(1) of the wave function for the quantum case. In addition, with the re-examination of the rel.tion between the magnetic fiel. B and its vector potential. A, we found that, in order to have a consistent formul.tion of the dynamics of the charged particl. with both expressions, we must have that B=∇×A if and onl. if B≠0.

关键词： Gauge Transformation Harmonic Oscil.ator Quantum Hal. Effect El.ctromagnetic Potential.

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Preval.nce of Hel.cobacter pyl.ri infection among patients with esophageal.carcinoma

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Worl. Journal.of Gastroenterol.gy 2024年第29期30卷 3479-3487页

作者： Miriam l.pez-Gómez Maria Moral.s Rebeca Fuerte Marta Muñoz Pedro-David Del.ado-l.pez jorge Francisco Gómez-Cerezo Enrique Casado Department of Medical.Oncol.gy Precision Oncology LaboratoryInfanta Sofía University HospitalSan Sebastián de los Reyes 28231MadridSpain Department of Medical.Oncol.gy Infanta Sofía University HospitalSan Sebastián de los Reyes 28702Spain Department of Internal.Medicine Infanta Sofía University HospitalSan Sebastián de los Reyes 28703MadridSpain Department of Pathol.gy Infanta Sofía University HospitalSan Sebastián de los Reyes 28702Spain Department of Neurosurgery Burgos University HospitalBurgos 09006Spain Department of Internal.Medicine Infanta Sofía University Hospital and Henares University Hospital Foundation for Biomedical Research and InnovationSan Sebastian de los Reyes 28702MadridSpain Department of Medical.Oncol.gy Infanta Sofia University Hospital and Henares University Hospital Foundation for Biomedical Research and InnovationSan Sebastian de los Reyes 28702MadridSpain

BACKGROUND Hel.cobacter pyl.ri(***)is a widespread microorganism rel.ted to gastric adenocarcinoma(AC).In contrast,it has been reported that an inverse association exists between *** infection and esophageal.*** mechanisms underl.ing this supposedl. protective effect remain *** To determine the preval.nce of *** infection in esophageal.carcinoma patients,we performed a retrospective observational.study of esophageal.tumors diagnosed in our *** We retrospectivel. reviewed the preval.nce of *** infection in a cohort of patients diagnosed with esophageal.*** or previous proton pump inhibitor(PPI)usage was al.o *** A total.of 89 patients with esophageal.carcinoma(69 mal.s,77.5%),with a mean age of 66 years(range,26-93 years)were *** was the most frequent pathol.gical.variant(n=47,52.8%),fol.owed by squamous cel. carcinoma(n=37,41.6%).Fourteen ACs(29.8%)originated in the gastroesophageal.junction and 33(70.2%)in the esophageal.***,54 patients(60.7%)presented at stages III and *** *** infection occurred onl. in 4 patients(4.5%),3 with AC(6.3%of al. ACs)and 1 with squamous cel. carcinoma(2.7%of al. squamous cel. tumors).Al. patients with previous *** infection had stage *** one patient had received prior *** eradication therapy,whereas 86(96.6%)had received previous or concomitant PPI *** In our cohort of patients,and after histol.gic eval.ation of paraffin-embedded primary tumors,we found a very l.w preval.nce of previous *** *** al.o reviewed the medical.history of the patients,concl.ding that the majority had received or were on PPI *** minimal.preval.nce of *** infection found in this cohort of patients with esophageal.carcinoma suggests a protective rol..

关键词： Hel.cobacter pyl.ri Eradication Esophageal.tumor Dysbiosis Proton pump inhibitors Carcinogenesis Microbiota Incidence

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Improving the radiol.gical.diagnosis of hepatic artery thrombosis after l.ver transpl.ntation: Current approaches and future chal.enges

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Worl. Journal.of Transpl.ntation 2024年第1期14卷 1-8页

作者： Cristian l.ndner Raúl.Riquel.e Rodrigo San Martín Frank Quezada jorge Val.nzuel. Juan P Maureira Martín Einersen Department of Radiol.gy Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Department of Radiol.gy Hospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile Department of Statistics Catholic University of MauleTalca 3460000Chile Neurovascul.r Unit Department of RadiologyHospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile

Hepatic artery thrombosis(HAT)is a devastating vascul.r compl.cation fol.owing l.ver transpl.ntation,requiring prompt diagnosis and rapid revascul.rization treatment to prevent graft *** present,imaging modal.ties such as ul.rasound,computed tomography,and magnetic resonance pl.y crucial.rol.s in diagnosing *** imaging techniques have improved sensitivity and specificity for HAT diagnosis,they have l.mitations that hinder the timel. diagnosis of this *** this sense,the emergence of artificial.intel.igence(AI)presents a transformative opportunity to address these diagnostic *** devel.pment of machine l.arning al.orithms and deep neural.networks has demonstrated the potential.to enhance the precision diagnosis of l.ver transpl.nt compl.cations,enabl.ng quicker and more accurate detection of *** articl. examines the current l.ndscape of imaging diagnostic techniques for HAT and expl.res the emerging rol. of AI in addressing future chal.enges in the diagnosis of HAT after l.ver transpl.nt.

关键词： l.ver transpl.ntation Postoperative compl.cations Hepatic artery Thrombosis Radiol.gy Artificial.intel.igence

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