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Computational solution of an acid-mediated tumor-growth radial model under logistic growth regimes for normal and cancer cells

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International Journal of Biomathematics 2023年第3期16卷 45-62页

作者： Farhan Khan Mudassar Abbas jorge e.macias-diaz Muhammad Bilal Khan Safar M.Alghamdi Department of Mathematics and Computer Sciences University of Palermo 90133 PalermoItaly Department of Mathematics and Applications “R.Caccioppoli”University of Naples Federico iiVia Cintia 80126NaplesItaly Department of Mathematics School of Digital Technologies Tallinn University10120 TallinnEstonia Departamento de Matematicas y Fisica Universidad Autonoma de Aguascalientes AguascalientesAgs.20131Merico Department of Mathematics COMSATS University Islamabad Islambad44000 Pakistan Department of Mathematics and Statistics College of Science Taif University Taif 21944Saudi Arabia

Tumor invasion follows a complex mechanism which involves cell migration and *** study the processes in which primary and secondary metastases invade and damage the normal cells,mathematical models are often extremely *** this paper,we present a mathematical model of acid-mediated tumor growth consisting of radially symmetric reaction-diffusion *** assumption on the radial symmetry of the solutions is imposed here in view that tumors present spherical symmetry at the microscopic ***,we consider various empirical mechanisms which describe the propagation of tumors by considering cancer cells,normal cells,and the concentration of H+*** other assumptions,we suppose that these components follow logistictype growth ***,this is an important difference with respect to various other mathematical models for tumor growth available in the ***,we also add competition terms of normal and tumor cells *** carry out a balancing study of the equations of the model,and a numerical model is proposed to produce *** practical remarks derived from our assumptions are provided in the discussion of our simulations.

关键词： Cancer growth model radially symmetric system acid-mediated tumor growth computer simulations

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A Study on the Density of Agglomerates Prepared from Cork Wastes

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Journal of Materials Science & Technology 2003年第1期19卷 46-50页

作者： A.macias-Garcia A.diaz-Parralejo 等 AreaofMaterialsScienceandMetallurgyengineering FacultyofIndustrialEngineeringUniversityofExtremadure06071BadaiozSpain AreaofMaterialsScienceandMetallurgyengineering FacultyofIndustrialEngineeringU

The density of black regranulate (BR) of cork and of black agglomerate (BA) and composite agglomerate (CA) prepared fromsuch a waste by different methods was investigated. The preparation of the agglomerates was undertaken by controlling thespecimen thickness for BA and the particle size for BR and the binder dosage for CA. The mass changes produced in theoven-drying treatment at 376.15 K of the agglomerates and in their subsequent stabilization under ambient conditions werealso analyzed. The density was determined by standard methods. For BR, the bulk density first decreased and then increasedwith decreasing particle size. It was much lower than the apparent density of the agglomeration products of cork. Although toa lesser extent, the density was also lower for BA than for CA. It was higher for the smaller thickness specimens of BA. In thecase of CA, the density followed the same variation trends as for BR. Furthermore it increased significantly with the increasein resin dosage. This resulted in a noticeable increase in the weight loss during the oven-drying and in a significant decreasein the degree of moisture adsorption during the stabilization period of the agglomerate.

关键词： Cork Agglomerates Density

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A novel and stretchable carbon-nanotube/Ni@TiO_(2):W photocatalytic composite for the complete removal of diclofenac drug from the drinking water

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Journal of environmental Sciences 2023年第4期126卷 575-589页

作者： ernesto Valadez-Renteria Rafael Perez-Gonzalez Christian Gomez-Solis Luis Armando diaz-Torres Armando encinas jorge Oliva Vicente Rodriguez-Gonzalez Consejo Nacional de Ciencia y Tecnología-División de Materiales Avanzados Instituto Potosino de Investigación Científica y TecnológicaSan Luis Potosí78216México División de Ciencias e Ingenierías Universidad de GuanajuatoLeón 37150México Grupo de espectroscopia de Materiales Avanzados y Nanoestructurados(GeMANA) Centro de Investigaciones enópticaA.C.Lomas Del CampestreLeón 37150México

We present the structural,morphological and photocatalytic properties of stretchable composites made with carbon nanotubes (CNTs),silicon rubber and Ni@TiO_(2):W nanoparticles(TiWNi NPs) with average size of 37±2 *** images showed that the TiWNi NPs decorated the surface of the CNT fibers,which are oriented in a preferential *** NPs presented a mixture of anatase/rutile phases with cubic *** performance of the TiWNi powders and stretchable composites was evaluated for the photocatalytic degradation of diclofenac (DCF) anti-inflammatory drug under ultraviolet-visible *** results revealed that the maximum DCF degradation percentages were 34.6%,91.9%,97.1%,98.5%and 100%for the CNT composite (stretched at 0%),TiWNi powders,CNT+TiWNi(stretched at 0%),CNT+TiWNi (stretched at 50%) and CNT+TiWNi (stretched at 100%),***,stretching the CNT+TiWNi composites was a good strategy to enhance the DCF degradation percentage from 97.1%to 100%,since stretching created additional defects (oxygen vacancies) that acted as electron sink,delaying the electron-hole recombination,and favors the DCF ***/absorbance measurements confirmed the presence of such ***,the reactive oxygen species (ROS) were determined by the scavenger’s experiments and found that the main ROS were the·OH and O_(2)-radicals,which attacked the DCF molecules,causing their *** results of this investigation confirmed that the stretchable CNT/TiWNi-based composites are a viable alternative to remove pharmaceutical contaminants from water and can be manually separated from the decontaminated water,which is unviable using photocatalytic powders.

关键词： Diclofenac Pharmaceutical contaminant TiO_(2) Carbon nanotubes Stretchable composite Photocatalysis

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Multitemporal landslide inventory analysis of an intertropical mountain in west-central Mexico——Basis for hazard management

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Journal of Mountain Science 2022年第6期19卷 1650-1669页

作者： Alejandro Cesar VALDeS CARReRA Manuel e.MeNDOZA Teodoro CARLÓN ALLeNDe Jose Luis macias Centro de Investigaciones en Geografia Ambiental Universidad Nacional Autonoma de MexicoMorelia 58190Mexico Consejo Nacional de Ciencia y Tecnologia-Instituto de Geofisica-Unidad Michoacan Universidad Nacional Autonoma de MexicoMorelia 58190Mexico Instituto de Geofisica-Unidad Michoacan Universidad Nacional Autonoma de MexicoMorelia 58190Mexico

Landslides in intertropical mountainous areas of Mexico are a natural hazard that could potentially generate a disaster. Despite this, many areas lack landslide inventories, making it difficult to monitor and efficiently manage the associated risks for local populations. For this reason, the aim of this research was to undertake a multitemporal landslide inventory and analyze its conditioning factors in the Pico de Tancítaro stratovolcano, which, in recent decades, has presented several high-risk geomorphological events with disastrous consequences for nearby localities. The spatial distribution of landslides and its conditioning factors were mapped at a 1:50,000 scale for the 1995-2020 period, through visual interpretation of orthophotos and satellite images(Landsat, SPOT, and SeNTINeL). The conditioning factors that link the most to landslides were Quaternary andesite and basaltic andesite rocks;volcanic cones, mountain river valleys, and very steep to steep slopes(30° to >45°), oriented to the South, North, and east;Andosols and Leptosols;and the oyamel fir and mixed forests. 505 landslide events classified into slides and flows that occurred in 1995, 2004, 2010, and 2015 were identified. New scars generated by the reactivation of landslide processes were also observed. The landslides in the study area were triggered by torrential rains caused by hurricanes and tropical storms;such as hurricanes Alex and Patricia. The inventory and analysis of conditioning factors highlighted the distribution and dynamics of slides and flows in the study area. In addition, the most important factors for studies of landslide susceptibility, hazards, and risks in the Pico de Tancítaro stratovolcano were identified, contributing to the management of geomorphological risks in intertropical mountain areas.

关键词： Geomorphology Mass wasting Natural hazards Pico de Tancítaro stratovolcano Risk management

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Influence of previous plane of nutrition on molecular mechanisms regulating the expression of urea and water metabolism related genes in the rumen and kidney of finishing crossbred Angus steers

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Animal Nutrition 2024年第2期17卷 232-243页

作者： Aghata e.Moreira da Silva Arturo macias Franco Bradley S.Ferguson Mozart A.Fonseca College of Agriculture Biotechnology&Natural Resources University of Nevada Department of Animal and Range Sciences Clayton Livestock Research Center New Mexico State University

This study aimed to understand how molecular mechanisms controlling water and urea metabolism at the finishing phase can be affected by previous plane of nutrition of crossbred Angus beef steers. Twentyfour(n = 24) animals were randomly distributed into either a moderate(MP) or high plane of nutrition during the background phase for 85 d. Animals were then blocked by their previous plane and were moved onto a 105-d finishing phase in a 2 × 2 factorial arrangement. The forage-finished group received only high-quality alfalfa hay, whereas the grain-fed group received a high grain diet(80% whole corn and20% alfalfa hay). By the end of the finishing phase, animals were harvested and tissue samples from the rumen and kidney were collected. Changes in gene expression of aquaporins(AQP)-2,-3,-4,-7, ATP1A1,ATP1B1, SGK1, CLIC1(kidney and rumen), UT-A1(kidney only) and UT-B(rumen only), were assayed via real-time q PCR; 18S r RNA was used as an endogenous control. One-way ANOVA followed by Tukey's post hoc analysis was conducted. When animals were from MP, forage-finishing increased the relative abundance of AQP3(P ≤ 0.05), AQP7(P ≤ 0.05), ATP1B1(P ≤ 0.05), and SGK1(P ≤ 0.05) in the kidney when compared to grain-fed animals. In the rumen, for the MP group, AQP7 was differentially expressed in both treatments at the finishing phase(P ≤ 0.01), with forage-finished steers having the highest expression of AQP7. For the MP group, UT-B had a tendency of presenting a higher expression on grainfed animals(P = 0.075). Overall, these results suggest that previous plane can impact expression of genes associated with water and urea metabolism during the finishing phase, namely AQP3, AQP7, ATP1B1, and SGK1 in the kidney, and AQP7 and UT-B in the rumen. The greatest impact observed on gene expression changes of investigated genes at the finishing phase was reflective of animals backgrounded on the moderate previous plane.

关键词： Gene expression Aquaporin Sodium channel Urea transporter

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零售业成功商业策略的研究 ——基于沃尔玛墨西哥的案例分析

零售业成功商业策略的研究 ——基于沃尔玛墨西哥的案例分析

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作者： Rene.macias diaz 华东理工大学

学位级别：硕士

本研究提出了一个简明、扼要的商业模式。其中的商业策略正是由沃尔玛墨西哥,世界领先的零售超市所采纳。该模式说明了哪些是公司共享信息,即能够清楚地、开放地与客户和供应商分享,并形成一个良性、动态的合作,使得利益相关者都能够获... 详细信息

本研究提出了一个简明、扼要的商业模式。其中的商业策略正是由沃尔玛墨西哥,世界领先的零售超市所采纳。该模式说明了哪些是公司共享信息,即能够清楚地、开放地与客户和供应商分享,并形成一个良性、动态的合作,使得利益相关者都能够获益。其中的一些策略正被其他公司实施或讨论,以期基于对沃尔玛的商业策略研究寻求对市场和全球经济有积极影响的商业模式。该项研究的资料及数据主要来源于关于运营管理和供应链管理和物流的学术文献,来自沃尔玛商店和出版社的在线电子文献,墨西哥官方相关数据,以及沃尔玛墨西哥官方网站的年度报告。

关键词：商业策略沃尔玛世界领先零售超市客户供应商市场全球经济学术文献书籍运营供应链管理物流互联网

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endoscopic management of complications of chronic pancreatitis

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World Journal of Gastroenterology 2013年第42期19卷 7308-7315页

作者： Jean-Marc Dumonceau Carlos macias-Gomez Division of Gastroenterology and Hepatology Geneva University Hospital1211 GenevaSwitzerland Gastrointestinal endoscopy Unit Gastroenterology ServiceItalian Hospital1181 Buenos AiresArgentina

Pseudocysts and biliary obstructions will affect approximately one third of patients with chronic pancreatitis(CP).For CP-related,uncomplicated,pancreatic pseudocysts(PPC),endoscopy is the first-choice therapeutic *** advances have focused on endosonography-guided PPC transmural drainage,which tends to replace the conventional,duodenoscope-based coma immediately *** material is being tested to facilitate the endosonography-guided *** this review,the most adequate techniques depending on PPC characteristics are presented along with supporting *** CP-related biliary obstructions,endoscopy and surgery are valid therapeutic *** co-morbidities(e.g.,portal cavernoma)and expected patient compliance to repeat endoscopic procedures are important factors when selecting the most adapted *** should be reasonably ruled out before embarking on the endoscopic treatment of presumed CP-related biliary *** endoscopy,the gold standard technique consists of placing simultaneous,multiple,side-by-side,plastic stents for a oneyear *** covered self-expandable metal stents are challenging this method and have provided 50%mid-term success.

关键词： Biliary stricture Chronic pancreatitis Pseudocyst endoscopic retrograde cholangio-pancreatography endoscopic ultrasonography Stent

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Mainstreaming the Full eNSO:Linking Present Weather and Future Climate

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International Journal of Disaster Risk Science 2022年第6期13卷 829-841页

作者： Michael H.Glantz Lino Naranjo-diaz Qian Ye Gregory e.Pierce Consortium for Capacity Building(CCB) University of Colorado BoulderBoulderCO 80301USA Integrated Risk Governance Program Beijing Normal UniversityBeijing 100875China

In this article we propose that all countries that are striving to become a Weather-Ready Nation(WRN)would beneft greatly from including el Niño-Southern Oscillation(eNSO)-related research findings into their decision-making processes,not only when an el Niño or a La Niña forecast has been issued *** an aspiring WRN,to beneft from eNSO information,such as disruptive or benefcial changes that could be foreseeably expected to occur in seasonal fow and in sub-seasonal hydrometeorological anomalies,requires its continuous mainstreaming about the status of the eNSO process into a WRN’s decision-making *** eNSO process provides a bridge between sub-seasonal weather anomalies and a sub-decadal climate phenomenon as well as a bridge between coping with weather extremes today and preparing for climate change-related hydrometeorological hazards in the *** extremes every few years provide a chance to evaluate a nation’s strategic and tactical responses to hydrometeorological hazard forecasts and *** successive eNSO extreme and its Neutral phase tests previously designed best *** of today’s youth and young professionals on climate,water,and weather issues has been increasing and will do so in coming *** awareness and attention to eNSO and away from eNSO extremes is *** heightened urgency for understanding the full eNSO“cycle”especially by youth and young professionals today is because they will soon be in professional positions that enable them to advise decision makers about climate policy *** understanding of the eNSO cycle is critically needed,as global warming is expected to continue to increase for the rest of the twentyfrst century.

关键词： eNSO WRN Hydromet Climate change Young professionals

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Inversion of electrical mobility measurements using bipolar or unipolar chargers for the arbitrary distribution of channels

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Particuology 2015年第3期13卷 114-123页

作者： M.Domat F.e.Kruis N.L.Azong-Wara J.M.Fernandez-diaz Department of Physics University of OviedoC/Calvo Sotelos/nE-33007 OviedoSpain Institute of Technology for Nanostructures(NST) and Center for Nanointegration Duisburg-essen(CeNIDe) University of Duisburg-EssenBismarckstr.81D-47057 DuisburgGermany

The inversion of the particle size distribution from electrical mobility measurements is analyzed. Three different methods are adapted for a dot-matrix approach to the problem, especially for non-square or singular matrices, and applied to electrical mobility measurements from fixed or scanning voltages. Mul- tiply charged particles, diffusion losses, arbitrary voltage steps and noise were considered, which results in non-adjoining and overlapping transfer functions. The individual contribution of the transfer func- tions in each size interval was geometrically estimated, which requires only its characteristic mobilities. The methodology is applied to mobility measurements from particles charged with unipolar and bipolar chargers. However, the method can be extrapolated to any charging method with a defined charge distribution, and retrieval of the singly charged particle distribution and mean charge from a tandem differential mobility analysis configuration was successfully demonstrated.

关键词： Tandem differential mobility analysisInverse problemRegularization methodsSize distributionTransfer functionUnipolar charger

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Avian preference for close proximity to human habitation and its ecological consequences

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Current Zoology 2018年第5期64卷 623-630页

作者： Anders Pape MOLLeR Mario diaz ecologie Systematique evolution CNRS Universite Paris-Sud AgroParisTech Universite Pari-Saclay 0rsay Cedex F-91400 France Department of Biogeography and Global Change (BGC-MNCN-CSIC) National Museum of Natural Sciences CSIC c/Serrano 155bis Madrid E-28006 Spain

Human proximity often have negative consequences for wildlife. However, animals may also benefit from human proximity in terms of availability of resources and protection against predators and parasites. We recorded the distance between all birds detected during the breeding season along 18 5-kin transects and the nearest inhabited house in three areas of 50 km2 in Spain, France, and Denmark. More than three quarters of birds were located closer than 100 m to the nearest house, while the null expectation was less than a third. Mean distance for species was correlated with degree of bird urbanization and with flight initiation distance. Habitat specialist species with small breeding territories tended to live closer to houses. Birds from species having more broods per year, larger annual fecundity and lower nest predation rate lived closer to human habitation. Breeding range size, population density, and continental breeding population sizes were larger for species living closer to human habitation. Most relationships between distance to houses and bird traits had a strong phylogenetic signal, but most additive trait effects remained after phylogenetic correction. Proximity to human habitation was a main driver of the distribution of birds, with most individuals and species tightly linked to inhabited houses. Living close to human habitation was associated with success in the colonization of urban habitats and with consistent changes in distribution, abundance, behavior, and life history. Replicated measurements of the spatial and tempo- ral variation in these distributions may be useful for monitoring and analyzing the ongoing process of organisms＇ urbanization.

关键词： birds distance to nearest house flight initiation distance humans refuge urbanization.

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