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在感病向日葵上,混合状态下的锈亩1号小种和3号小种的...

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国外农学（向日葵） 1991年第4期 43-46,37页

作者： sack.,WE 魏守恩

经口免疫毒素源性大肠杆菌的家兔抗肠内攻击做为改进的RITARD模型

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微生物学免疫学译刊 1988年第2期 36-37页

作者： R.Bradle sack 罗建辉

有效的抗毒素源性大肠杆菌口服菌苗的进展,有赖于识别适应的保护性抗原,这种

关键词：毒素源性大肠杆菌经口 RITARD 保护力家兔肠内

Lyell Syndrome with Fatal Outcome in Two Pregnant Women Receiving Antiretroviral Therapy in Guinea Conakry

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Journal of Cosmetics, Dermatological Sciences and Applications 2013年第2期3卷 135-138页

作者： Mohamed Cissé Mohamed Maciré Soumah Thierno Mamadou Tounkara Boh Fanta Diané Fodé Bangaly sack Houleymatou Baldé Amara Camara Aissata Dabo Camara Alhousseini Doumbouya Dermatology-STD Donka Teaching Hospital Gamal Abdel Nasser University of Conakry Conakry Guinea Infectious and Tropi- cal Diseases Donka Teaching Hospital Gamal Abdel Nasser University of Conakry Conakry Guinea

An old woman, 28 years old, weighing 74 kg was referred for skin detachment associated with bubbles and mucosal erosions. This clinical picture had occurred 15 days after the institution of a triple combination: AZT (300 mg) + 3TC (150 mg) and nevirapine (200 mg), during a pregnancy of 20-week gestation. The woman was in her third gestation. The second case is aged 26, weighing 65 kg. This clinical picture had occurred 20 days after the administration of a triple therapy combination: AZT (300 mg) + 3TC (150 mg) and nevirapine (200 mg), during a pregnancy of 32-week gestation. It was the fourth gestation. The birth of a stillborn had occurred the day before his admission into our service. The diagnosis of Toxic Epidermal Necrolysis with nevirapine was selected on the basis of the clinical and anamnestic arguments. The biological tests showed the following results: transaminases (ALT and AST) were within normal limits, blood glucose, and urea > 10 mmol/l. The evolution was marked by the patient death to Day 9 (D9) and at D2 of hospitalization. Discussion: NET and the SJS have been reported in pregnant women as potentially dangerous complications that are often associated with suspected drugs. Among these drugs, antiretroviral drugs, prescribed to pregnant women to prevent mother to child transmission of HIV are often reported. Our case is an illustration of the problem of HIV management in pregnant women. It also focuses on the association between pregnancy and Toxic Epidermal Necrolysis. Nevirapine is an effective drug in the regimens proposed in the management of HIV patients in limited resources countries. But the high frequency of toxidermia with this drug should lead to its replacement by other antiretrovirals least providers of toxidermia as anti proteases in the context of PMTCT programs.

关键词： Lyell Pregnant Women Nevirapine Fatal Outcome

心房颤动心律转复的长期后果:利用P波信号平均ECG和化学反射敏感性检测预测复发

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世界核心医学期刊文摘（心脏病学分册） 2007年第2期3卷 51-52页

作者： Budeus M. Wieneke H. sack S. 刘少伟 Department of Cardiology West-German Heart Centre University of Duisburg Essen Germany

目的:心律转复后心房颤动复发是临床实践中的普遍问题。方法:作者在连续118例成功实施心脏电复律1d后的患者中验证如下假说,即心房颤动复发可通过测定P波触发的P波信号平均ECG和化学反射敏感性(CHRS)进行预测。用P波触发的P波信号平均EC... 详细信息

目的:心律转复后心房颤动复发是临床实践中的普遍问题。方法:作者在连续118例成功实施心脏电复律1d后的患者中验证如下假说,即心房颤动复发可通过测定P波触发的P波信号平均ECG和化学反射敏感性(CHRS)进行预测。用P波触发的P波信号平均ECG测定滤过的P波间期(FPD)和最后20msP波电压的均方根(RMS 20)。

关键词：心房颤动 ECG P波化学反射敏感性检测心脏电复律临床实践均方根复发风险比值计

生长激素抑制素治疗先天性乳糜性胸水可导致新生儿—过性甲状腺功能减退

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世界核心医学期刊文摘（儿科学分册） 2005年第11期1卷 14-15页

作者： Maayan-Metzger A. sack J. Mazkereth R. 朱新菊

Aim: To describe a group of neonates with congenital, non-traumatic chylothorax, one of whom developed transient hypothyroidism following treatment with somatostatin. Methods: The charts of seven infants with congenital chylothorax were reviewed in terms of their clinical presentation, the severity of their disease, the complications they presented and the duration of their hospitalization. Their pituitary-thyroid axis function was monitored in particular. Results: The seven infants, all preterm (32-34wk), suffered from congenital chylothorax and hydrops fetalis diagnosed during the prenatal period. Four were treated by intrauterine drainage, and four had congenital malformations. Hospitalization lasted from 32 to 120 d. Three of the infants suffered from thrombocytopenia, three had chronic lung disease, and one suffered from Gram-negative sepsis. The infant treated with somatostatin initially had normal thyroid function, but later developed primary transient hypothyroidism and was treated with L-thyroxine. The thyroid screening tests for the infants who were not treated with somatostatin were all normal. Conclusions: Repeated doses of somatostatin were effective in reducing chylus production. Administering this treatment earlier should be considered in order to minimize known complications. The only potential side effect observed was primary transient hypothyroidism. Therefore, careful monitoring of the pituitary-thyroid axis is advised.

关键词：乳糜性胸水生长激素抑制素甲状腺功能减退慢性肺疾病左旋甲状腺素甲状腺功能正常甲状腺轴革兰阴性菌胸水引流脓毒症

A new method for internal cardioversion in patients with persistent atrial fibrillation

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Chinese Medical Journal 2002年第2期000卷 139-141页

作者：周京敏 Stefan sack Frank Heinzel Peter Hunold Nicklas Dagres Raimund Erbel 葛均波 Department of Cardiology Zhongshan Hospital Shanghai Institute of Cardiovascular Diseases Fudan University Department of Cardiology University Essen Hospital Essen 45122 Germany

Coronary microvascular dysfunction exists early after hearttransplantationand normalisation during followup :serial assessment with intracoronaryFlo Wire

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Chinese Medical Journal 1999年第9期112卷 81-81页

作者： JGe DWelge AJeremias GGorge FLiu Ssack CReidemeister RErbel Department of Cardiology University-GHS Essen Germany Department of Cardiac Surgery University-GHS Essen Germany

In order to assess the vascular integrity after heart transplantation (HTx), intracoronary Doppler was performed in 13 patients within 3 months after HTx and at one year follow up in all the 3 epicardial coronary arteries (LAD, LCX, and RCA) For intracoronary Doppler flow mapping, a 0 014 inch,15 MHz FloWire (Cardiometrics) was used Coromary flow velocity reserve (CFR) was derived by calculating the ratio between average peak flow velocity (APV) at baseline and after intracoronary adenosine injection (LAD and LCX, 18?μg; RCA, 12?μg) All patients were found to have relatively normal coronary angiograms within 3 months and at one year follow up CFVR was increased significantly in LAD (2 87±0 59 vs 3 63±0 91, P 0 05) Reduction of CFR exists within 3 months after HTx and normalises within one year This indicates that microvascular dysfunction especially in LAD and LCX exists early after HTx which will be normalised at 1 year CFR of the RCA seems to recover early HTx

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失眠的评估和处理

美国医学会杂志（中文版） 2004年第4期23卷 208-211页

作者： CarlosH．Schenck MarkW．Mahowald RobertL．sack 黄觉斌谭铭勋

失眠是一种常见的可治性疾病，其特点为睡眠时间不足或睡眠质量太差，因而出现日间不良后果。失眠可以表现为人睡困难(睡眠潜伏期延长)、保持睡眠状况困难(过多或较长时间的觉醒)或感觉不能从睡眠中得到恢复。失眠可以原发于儿童时期或... 详细信息

失眠是一种常见的可治性疾病，其特点为睡眠时间不足或睡眠质量太差，因而出现日间不良后果。失眠可以表现为人睡困难(睡眠潜伏期延长)、保持睡眠状况困难(过多或较长时间的觉醒)或感觉不能从睡眠中得到恢复。失眠可以原发于儿童时期或稍后年龄段，也可以由继发性障碍(心理生理因素)引起，或者伴随精神、躯体及其他睡眠障碍而发生。失眠可以是一过性的(由于应激、疾病或外出旅行等原因)，也可以是慢性的(每夜失眠持续6个月以上)。持续性难治性失眠是发生重性抑郁症的一个重要危险因素。注意应该把失眠同睡眠错觉(sleep-state mispereeption)和无症状的短睡眠状态(short sleep states)区分开来。

关键词：失眠睡眠时间睡眠状态流行病学精神病

孟加拉国农村0～2岁儿童人群的腹泻疾病发生率和危险因素

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世界核心医学期刊文摘（儿科学分册） 2006年第A10期2卷 6-7页

作者： Pathela P. Hasan K.Z. Roy E. R.B. sack 张振 Department of International Health Johns Hopkins University Bloomberg School of Public Health 615 N.Wolfe St. Baltimore MD 21205 United States

Aim: To describe clinical characteristics and age- and season- specific incidences of diarrheal episodes, and to evaluate risk factors associated with the occurrence of diarrheal disease. Methods: A total of 252 infants from rural Bangladesh were followed through household surveillance for 2 y from birth during the years 1993- 1996. Demographic and household determinants were linked to the probability of illness using logistic regression models. Results: The overall incidence of diarrhea was 4.25 episodes per child per year. Peak rates of overall, acute, and persistent diarrhea occurred in the 6- 11- mo and 12- 17- mo age groups. Diarrheal rates peaked during the spring and summer. Among host- related characteristics, having a sibling in the household and having had prior diarrhea were significant risk factors for diarrhea. Among environmental characteristics, spring season remained a highly statistically significant risk factor for diarrhea. Conclusion: Diarrheal disease continues to be a substantial burden in young children in rural Bangladesh. Most diarrheal episodes are of short duration, and should primarily be treated with oral rehydration therapy to prevent diarrhea- related mortality. Improved knowledge of oral rehydration therapy, feeding during episodes to prevent further malnutrition, prolonged breastfeeding, and the keeping of livestock in corralled areas of the home areadvocated.

关键词：疾病发生率持续性腹泻口服补液疗法腹泻病腹泻发病率总体发病率统计学显著性相关性因素龄组