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Comparison of open and closed hyperthermic intraperitoneal chemotherapy: Results from the United States hyperthermic intraperitoneal chemotherapy collaborative

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World Journal of Gastrointestinal Oncology 2020年第7期12卷 756-767页

作者： Jennifer L Leiting jordan m Cloyd Ahmed Ahmed Keith Fournier Andrew J Lee Sophie Dessureault Seth Felder Jula Veerapong Joel m Baumgartner Callisia Clarke Harveshp mogal Charles A Staley mohammad Y Zaidi Sameer H Patel Syed A Ahmad Ryan J Hendrix Laura Lambert Daniel E Abbott Courtney Pokrzywa mustafa Raoof Christopher J LaRocca Fabian m Johnston Jonathan Greer Travis E Grotz Division of Hepatobiliary and Pancreas Surgery Mayo ClinicRochesterMN 55901United States Division of Surgical Oncology Department of SurgeryThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Surgical Oncology University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Gastrointestinal Oncology Moffitt Cancer CenterDepartment of Oncologic SciencesMorsani College of MedicineTampaFL 33612United States Division of Surgical Oncology Department of SurgeryUniversity of CaliforniaSan DiegoCA 92093United States Division of Surgical Oncology Department of SurgeryMedical College of WisconsinMilwaukeeWI 53226United States Division of Surgical Oncology Winship Cancer InstituteEmory UniversityAtlantaGA 30322United States Department of Surgery University of Cincinnati College of MedicineCincinnatiOH 45267United States Division of Surgical Oncology Department of SurgeryUniversity of Massachusetts Medical SchoolWorcesterMA 01655United States Peritoneal Surface malignancy Program Section of Surgical Oncology Huntsman Cancer InstituteUniversity of UtahSalt Lake CityUT 84112United States Division of Surgical Oncology Department of SurgeryUniversity of WisconsinMadisonWI 53792United States Christopher La Rocca Division of Surgical OncologyDepartment of SurgeryCity of Hope National Medical CenterDuarteCA 91010United States Department of Surgery Johns Hopkins UniversityBaltimoreMD 21287United States

BACKGROUND Cytoreductive surgery(CRS)with hyperthermic intraperitoneal chemotherapy(HIPEC)for peritoneal carcinomatosis can be performed in two ways:Open or closed abdominal *** To evaluate the impact of HIPEC method on post-operative and long-term survival *** Patients undergoing CRS with HIPEC from 2000-2017 were identified in the United States HIPEC collaborative ***-operative,recurrence,and overall survival outcomes were compared between those who received open vs closed *** Of the 1812 patients undergoing curative-intent CRS and HIPEC,372(21%)patients underwent open HIPEC and 1440(79%)underwent closed *** was no difference in re-operation or severe complications between the two *** HIPEC had higher rates of 90-d readmission while open HIPEC had a higher rate of 90-d *** multi-variable analysis,closed HIPEC technique was not a significant predictor for overall survival(hazards ratio:0.75,95%confidence interval:0.51-1.10,P=0.14)or recurrence-free survival(hazards ratio:1.39,95%confidence interval:1.00-1.93,P=0.05)in the entire *** findings remained consistent in the appendiceal and the colorectal *** In this multi-institutional analysis,the HIPEC method was not independently associated with relevant post-operative or long-term *** technique may be left to the discretion of the operating surgeon.

关键词： mucinous appendiceal carcinoma Cytoreductive surgery multi-institutional

Extensive Study of Cloud Computing Technologies, Threats and Solutions Prospective

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Computer Systems Science & Engineering 2022年第4期41卷 225-240页

作者： mwaffaq Abu-Alhaija Nidal m.Turab AbdelRahman Hamza Department of Networks and Information Security Faculty of Information TechnologyAl-Ahliyya Amman UniversityAmman19328Jordan Department of Computer Science Information TechnologyAl-Ahliyya Amman UniversityAmman19328Jordan

Infrastructure as a Service(IaaS)provides logical separation between data,network,applications and machines from the physical constrains of real *** is one of the basis of cloud ***,security issues are also gradually emerging with virtualization of cloud *** security aspects of cloud virtualization will be explored in this research paper,security recognizing potential threats or attacks that exploit these vulnerabilities,and what security measures are used to alleviate such *** addition,a dis-cussion of general security requirements and the existing security schemes is also *** shown in this paper,different components of virtualization environ-ment are targets to various attacks that in turn leads to security issues compromis-ing the whole cloud *** this paper an overview of various cloud security aspects is also *** attack scenarios of virtualization envir-onments and security solutions to cater these attacks have been discussed in the *** then proceed to discuss API security concerns,data security,hijacking of user account and other security *** aforementioned discussions can be used in the future to propose assessment criteria,which could be useful in ana-lyzing the efﬁciency of security solutions of virtualization environment in the face of various virtual environment attacks.

关键词： Cloud computing environment paravirtualization full virtualization cloud virtualization security hypervisor virtual machines

Schuhli锁定螺母加强钢板治疗骨质疏松肱骨骨折的生物力学研究

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中国临床解剖学杂志 2007年第1期25卷 77-80页

作者：白波徐谦 Jazrawi Laith m Simon jordan A Kummer Frederick J Birdzell Luther T Koval Kenneth J 广州医学院第一附属医院骨科广州510120 纽约大学关节疾病专科医院骨科及运动医学研究中心

目的:评价骨质疏松肱骨骨折中Schuhli锁定螺母替代骨水泥增强钢板内固定稳定性的效果。方法:分别用Schuhli锁定螺母配标准螺钉和骨水泥加强螺钉对骨质疏松的肱骨干骨折模型行钢板内固定,在3种加载模式下测试其内固定的强度和稳定性,并... 详细信息

目的:评价骨质疏松肱骨骨折中Schuhli锁定螺母替代骨水泥增强钢板内固定稳定性的效果。方法:分别用Schuhli锁定螺母配标准螺钉和骨水泥加强螺钉对骨质疏松的肱骨干骨折模型行钢板内固定,在3种加载模式下测试其内固定的强度和稳定性,并与标准固定组进行对比。再在4.5N m扭矩下将肱骨干循环扭转1000次,在同样模式下测试内固定的强度和稳定性。结果:循环扭转前后,锁定螺母组和骨水泥加强组在扭转加载模式下的内固定稳定性均明显高于标准固定组(循环前高出6～14倍,循环后高出3～3.6倍);而两组组间比较,在各加载模式下的内固定稳定性差异均不明显(P>0.05)。在轴压和四点弯曲模式下,两组循环扭转前的内固定稳定性与标准固定组比较亦无明显差异(P>0.05)。结论:使用Schuhli锁定螺母可获得与骨水泥加强同样的稳定性,还可避免水泥外渗和骨质热坏死的发生而影响骨折的愈合。

关键词：骨质疏松骨折肱骨内固定生物力学

Portraying Diabetic Foot Ulcers: Comparative Evaluation of Diabetic Foot Infections versus Diabetic Foot Ulcers

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Advances in Infectious Diseases 2024年第2期14卷 297-309页

作者： Jamal Wadi Al Ramahi Leen Sharqawi Sarah AL-Najafi Eman Awwad Haya m. Al-Obaidi Abdel Hafez mohammad Sara Nofal Dina Riyadh Al-Janabi Ibrahim Zuhair Hamza Jamal Al-masaeid mohammed Al-Ithawi Dina Rasheed Bellal O. Al-Far Osama Al-Izi Qutaiba Al-Bustanji School of medicine The University of Jordan Amman Jordan Department of the Internal medicine The Specialty Hospital Amman Jordan Department of Pharmacy The Specialty Hospital Amman Jordan Department of the medical Al Khalidi Hospital Amman Jordan Department of Pharmacy Jordan Hospital Amman Jordan Department of Internal medicine Jordan Hospital Amman Jordan Department of General Surgery Jordan Hospital Amman Jordan

Background: Confusion often arises in caring for diabetic foot infections and ulcers, especially with antimicrobials;we aim to shed light on this entity and alert healthcare workers to its stewardship. methods: Records were reviewed between February 2016 and September 2023. Data for patients diagnosed with diabetes and foot ulcers, infected or not, were examined following ICD 9 search terms. Records for patients were included if they were prediabetic/diabetic adults with foot ulcers, more than 18 years old, and on antidiabetic treatment. Patients were excluded if they insulin resistant, with normal HgbA1c levels, wheel-chair dependent, bed-bound, non-diabetic patients, diabetic patients who had vascular lower limb surgery earlier to ulcers, diabetic patients who had aortocoronary bypass, deep venous thrombosis within six months, malignancy, and severe clinical depression. A modified IWGDF/IDSA guidelines definitions for DFI and DFU was considered. Statistical analysis was done using R programming. Statistical methods were employed as appropriate, and a significant P-value was considered for P Results: most characteristics were well balanced between DFI and DFU, on imaging osteomyelitis and tissue swelling were significantly more in DFI. Endovascular radiological procedures showed angiograms to be considerably more in DFI, while angioplasty was more in DFU, in addition to smoking. Bacteremia was uncommon, and swab cultures were mostly polymicrobial in both ulcers;no clear association with blood bacteria was detected with the polymicrobial growth, though few were concordant. Antimicrobials prescribed for both ulcers were not statistically different except for carbapenems, which were more in DFI (P Conclusion: Attention should be paid to best practices while caring for diabetic ulcers. These include swab culture interpretations, the use of antimicrobials, and plan management according to DFI or DFU to utilize either local care or combination with antimicrobials.

关键词： Diabetic Foot Ulcers Diabetic Limb Amputation Antimicrobials Stewardship Broad-Spectrum Antimicrobials in Diabetic Foot Ulcers

T cell immune responses to SARS-CoV-2 and variants of concern(Alpha and Delta)in infected and vaccinated individuals

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Cellular & molecular Immunology 2021年第11期18卷 2554-2556页

作者： Stanley C.jordan Bong-Ha Shin Terry-Ann m.Gadsden maggie Chu Anna Petrosyan Catherine N.Le Rachel Zabner Jillian Oft Isabel Pedraza Susan Cheng Ashley Vo Noriko Ammerman Jasmine Plummer Shili Ge max Froch Anders Berg mieko Toyoda Ruan Zhang Comprehensive Transplant Center Transplant Immunology LaboratoryCedars-Sinai Medical CenterLos AngelesCAUSA Division of Infectious Diseases Cedars-Sinai Medical CenterLos AngelesCAUSA Department of Cardiology Cedars-Sinai Medical CenterLos AngelesCAUSA Department of Bioinformatics&Functional Genomics Cedars-Sinai Medical CenterLos AngelesCAUSA Department of Pathology&Laboratory medicine Cedars-Sinai Medical CenterLos AngelesCAUSA

Our understanding of immune responses to SARS-CoV-2 and variants of concern(VOCs)has been primarily acquired through analysis of Spike-specific IgG ***,a more comprehensive understanding of the breadth and longevity of immune responses after infection and vaccination requires analysis of cellular ***,we report on T cell immunity in infected and vaccinated individuals,identifying CD4+/CD8+T cell cytokine responses to SARS-CoV-2 and variant peptides(Alpha,B.1.1.7 and Delta,B.1.617.2).

关键词： Alpha infected immunity

A Novel method for Thermoelectric Generator Based on Neural Network

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Computers, materials & Continua 2022年第10期73卷 2115-2133页

作者： mohammad Saraireh A.m.maqableh manar Jaradat Omar A.Saraereh mechanical Engineering Department Faculty of EngineeringMutah UniversityKarak61710Jordan Electromechanical Engineering Department Luminus Technical University CollegeAmman11118Jordan Department of Computer Engineering Faculty of EngineeringThe Hashemite UniversityZarqa13133Jordan Department of Electrical Engineering Faculty of EngineeringThe Hashemite UniversityZarqa13133Jordan

The growing need for renewable energy and zero carbon dioxide emissions has fueled the development of thermoelectric generators with improved power generating *** with the endeavor to develop thermoelectric materials with greater figures of merit,the geometrical and structural optimization of thermoelectric generators is equally critical for maximum power output and *** energy strategies that are constantly updated are a viable option for addressing the global energy issue while also protecting the *** have been significant focuses on the development of thermoelectric modules for a range of solar,automotive,military,and aerospace applications in recent years due to various advantages including as low vibration,great reliability and durability,and the absence of moving *** order to enhance the system performance of the thermoelectric generator,an artificial neural network(ANN)based algorithm is ***,to achieve high efficiency and system stability,a buck converter is designed and *** and experimental findings demonstrate that the suggested method is viable and available,and that it is almost similar to the real value in the steady state with the least power losses,making it ideal for vehicle exhaust thermoelectric generator ***,the proposed hybrid algorithm has a high reference value for the development of a dependable and efficient car exhaust thermoelectric generating system.

关键词： Thermoelectric system thermodynamics electromechanics rotational factors neural networks

Big Data Bot with a Special Reference to Bioinformatics

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Computers, materials & Continua 2023年第5期75卷 4155-4173页

作者： Ahmad m.Al-Omari Shefa m.Tawalbeh Yazan H.Akkam mohammad Al-Tawalbeh Shima’a Younis Abdullah A.mustafa Jonathan Arnold Biomedical Systems and Informatics Engineering Department Yarmouk UniversityIrbid21163Jordan Department of medicinal Chemistry and Pharmacognosy Yarmouk UniversityIrbid21163Jordan Department of Electrical Computer and Software EngineeringUniversity of Ontario Institute of TechnologyOshawaL1H7K4Canada Department of mechanical Engineering University of MosulMosul41001Iraq Genetics Department University of GeorgiaAthens30602GAUSA

There are quintillions of data on deoxyribonucleic acid(DNA)and protein in publicly accessible data banks,and that number is expanding at an exponential *** scientific fields,such as bioinformatics and drug discovery,rely on such data;nevertheless,gathering and extracting data from these resources is a tough *** data should go through several processes,including mining,data processing,analysis,and *** study proposes software that extracts data from big data repositories automatically and with the particular ability to repeat data extraction phases as many times as needed without human *** software simulates the extraction of data from web-based(point-and-click)resources or graphical user interfaces that cannot be accessed using command-line *** software was evaluated by creating a novel database of 34 parameters for 1360 physicochemical properties of antimicrobial peptides(AmP)sequences(46240 hits)from various mARVIN software panels,which can be later utilized to develop novel ***,for machine learning research,the program was validated by extracting 10,000 protein tertiary structures from the Protein Data *** a result,data collection from the web will become faster and less expensive,with no need for manual data *** software is critical as a first step to preparing large datasets for subsequent stages of analysis,such as those using machine and deep-learning applications.

关键词： Bioinformatics big data data extraction bot drug design

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回声之真

英语沙龙（高中） 2015年第2期 11-13页

作者： jordan m. Fayetteville, AR 加亮

一位少年在随父亲一起穿越山洞石穴时，聆听到回声跃动出最原始的音律，感受到回声爆发出最本真的活力，从而触发了对生命中更深层次意义的感怀。

关键词：英语学习学习方法阅读知识阅读材料

Receiving antenatal care via mobile clinic: Lived experiences of jordanian mothers

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International Journal of Nursing Sciences 2023年第2期10卷 230-237页

作者： Hala A.Bawadi Asma’a S.Abu Abed Zaid m.Al-Hamdan Safa m.Alzubi maternal and Child Health Department School of Nursing the University of JordanAmmanJordan National Women Health Center(resigned) Royal Medical ServicesAmmanJordan Faculty of Nursing jordan University of Science and Technology IrbidJordan Royal medical Services AmmanJordan

Objective To understand the perceptions of pregnant jordanian women who received antenatal care via mobile clinic,and to contribute new insights into the experiences of these mothers and how they evaluated the services that were *** Ten jordanian mothers who had received antenatal care at a mobile clinic discussed their experiences in semi-structured,audiotaped interviews in a study that adopted a qualitative research *** analysis was done using interpretative phenomenological *** Three main themes were identified:Being informed about the medical campaign or missing the opportunity of being informed;The experience of receiving antenatal care was wonderful,although there was only one thing lacking;and they safeguard our life and take any opportunity to educate *** Data indicate that the mothers were largely satisfied with most facets of the antenatal care services they had received at the mobile ***,while services are generally well received,there are clear opportunities for ameliorating the quality of services *** mothers living in remote,deprived areas,outreach is not just an‘optional extra’but rather an essential service.

关键词： jordan mobile health units Pregnancy Pregnant women Prenatal care Qualitative research