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辣椒杂志 2013年第1期11卷 38-47页

作者： Koeun Han Hee-Jin Jeong joohee sung Young Soo Keum Myeong-Cheoul Cho Jeong-Han Kim Jin-Kyung Kwon Byung-Dong Kim Byoung-Cheorl Kang 孔秋生(译) 植物学系植物基因组学和育种研究所农业和生命科学研究院农业科学学院国立首尔大学应用生命化学系农业科学学院国立首尔大学蔬菜研究室国家园艺和中草药研究所农村发展局华中农业大学园艺林学学院

辣椒由于含有生物碱化合物辣椒素和辣椒素类物质(capsaicinoids)而具有独特的辣味。虽然辣椒素类物质已被证实对人体健康有药理和生理作用,但由于具有辛辣味,使得辣椒素类物质的应用受到限制。在无辣味的辣椒中发现的辣椒素酯类物质(cap... 详细信息

辣椒由于含有生物碱化合物辣椒素和辣椒素类物质(capsaicinoids)而具有独特的辣味。虽然辣椒素类物质已被证实对人体健康有药理和生理作用,但由于具有辛辣味,使得辣椒素类物质的应用受到限制。在无辣味的辣椒中发现的辣椒素酯类物质(capsinoids)与辣椒素类物质具有非常相近的结构和相似的生物效应。以前的研究表明,p-AMT基因突变与辣椒素酯类物质的产生相关,然而,辣椒素酯类物质的合成途径尚未被完全阐明。在本研究中,我们对F6重组自交系群体进行了遗传分析,以确定辣椒素酯类物质的合成机制。在这个群体中,辣椒素酯类物质的产生与否表现出了与具有Pun1位点的基因型植株的共分离。此外,我们筛选了辣椒素酯类物质的合成模式,以及在p-AMT突变系中Pun1位点与辣椒素酯类物质合成的相关性。在辣椒种质中,我们筛选到p-AMT基因中PLP结合结构域中的氨基酸取代突变体。隐性pun1基因存在时不合成辣椒素酯类物质,同时还发现p-AMT突变型和辣椒素酯类物质的含量之间并无关系。由此认为Pun1基因不仅负责辣椒素类物质合成,同时也控制着辣椒素酯类物质的合成。

关键词：辣椒素合成酶辣椒属辣味 Pun1 拟转氨酶

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Computational discovery of p-type transparent oxide semiconductors using hydrogen descriptor

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npj Computational Materials 2018年第1期4卷 503-509页

作者： Kanghoon Yim Yong Youn Miso Lee Dongsun Yoo joohee Lee sung Haeng Cho Seungwu Han Department of Materials Science and Engineering and Research Institute of Advanced Materials Seoul National UniversitySeoul 08826Korea Electronics and Telecommunications Research Institute(ETRI) Daejeon 34129Korea Korea Institute of Energy Research Daejeon 34129Korea

The ultimate transparent electronic devices require complementary and symmetrical pairs of n-type and p-type transparent *** several n-type transparent oxide semiconductors like InGaZnO and ZnO are available and being used in consumer electronics,there are practically no p-type oxides that are comparable to the n-type counterpart in spite of tremendous efforts to discover ***,high-throughput screening with the density functional theory calculations attempted to identify candidate p-type transparent oxides,but none of suggested materials was verified experimentally,implying need for a better theoretical ***,we propose a highly reliable and computationally efficient descriptor for p-type dopability—the hydrogen impurity *** show that the hydrogen descriptor can distinguish well-known p-type and n-type *** the hydrogen descriptor,we screen most binary oxides and a selected pool of ternary compounds that covers Sn^(2+)-bearing and Cu^(1+)-bearing oxides as well as *** a result,we suggest La_(2)O_(2)Te and CuLiO as promising p-type oxides.

关键词： transparent semiconductors oxide

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Multivalent network modifier upregulates bioactivity of multispecies biofilm-resistant polyalkenoate cement

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Bioactive Materials 2022年第8期7卷 219-233页

作者： Ji-Yeong Kim Woojin Choi Utkarsh Mangal Ji-Young Seo Tae-Yun Kang joohee Lee Taeho Kim Jung-Yul Cha Kee-Joon Lee Kwang-Mahn Kim Jin-Man Kim Dohyun Kim Jae-sung Kwon Jinkee Hong sung-Hwan Choi Department of Orthodontics Institute of Craniofacial DeformityYonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea BK21 FOUR Project Yonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea Department of Chemical and Biomolecular Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea Department and Research Institute of Dental Biomaterials and Bioengineering Yonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea Johns Hopkins University 3400 N.Charles St.Mason HallBaltimoreMD 21218USA Department of Oral Microbiology and Immunology School of Dentistry and Dental Research InstituteSeoul National UniversitySeoul 08826Republic of Korea Department of Conservative Dentistry Oral Science Research CenterYonsei University College of Dentistry50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

Polyalkenoate cement(PAC)is a promising material for regenerative hard tissue *** ionically rich glass component of PAC encourages bioactive interaction *** release of essential ***,PAC bioactivity is restricted owing to(i)structurally inherent cationic network formers and(ii)surface bacterial biofilm *** two factors cause a deficiency in ion release,further complicated by secondary infections and premature therapeutic ***,a multivalent zwitterionic network modifier(mZM)is presented for upregulation of ionic exchange and bioactivity *** introducing a non-zero charged mZM into PACs,an increase in the proportion of non-bridging oxygen *** network modification promotes ion channel formation,causing a multiple-fold increase in ion release and surface deposition of hydroxy-carbonate apatite(ca.74%).Experiments ex vivo and animal models also demonstrate the efficient remineralization ability of the ***,divalent cationic interaction results in bacterial biofilm reduction(ca.68%)while also influencing a shift in the biofilm species composition,which favors commensal ***,PAC modification with mZM offers a promising solution for upregulation of bioactivity,even aiding in customization by targeting site-specific regenerative therapy in future applications.

关键词： Multivalent network modifier Bioactive materials Glass polyalkenoate cement Ion release Remineralization Multispecies biofilm resistance

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Dipsacussaponin C from <i>Dipsacus asper</i>Reduces the Risk of Gastritis and Gastric Ulcer in Rats

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Food and Nutrition Sciences 2012年第7期3卷 931-941页

作者： Seon A. Hwang In Young Hwang joohee Jung Hye Kyung Kang Kun Ho Son Choon Sik Jeong College of Pharmacy Duksung Women’s University Seoul 132-714 South Korea College of Pharmacy Duksung Women’s University Seoul Korea Department of Food Science and Nutrition Andong National University Gyeongbuk 760-749 South Korea

The roots of Dipsacus asper (DA) have been used as a tonic and analgesic agent in traditional Chinese medicine for the treatment of osteoporosis, low back pain, knee pain, and as an anti-inflammatory agent. Few studies have reported pharmacological gastric activities. In this study, we investigated the effects of dipsacussaponin C (DSC) and 70% ethanol and water extracts of DA on gastritis and gastric ulcer in rat. First, we examined the free radical scavenging effect by the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay. Second, we examined the Helicobacter pylori (H. pylori) colonization inhibitory effect and found that DSC has a mild anti-H. pylori effect. Third, the cytotoxicity was assessed by measuring the cell viability of human gastric cancer cells (SNU638 and AGS). Also, we observed the acid-neutralizing capacity by measuring NaOH consumption volume and found that DSC is effective as an antacid agent. For these reasons, we observed the effect of DSC on HCl?ethanol-induced gastritis and indomethacin-induced gastric ulcer in rat. In pylorus-ligated rats, DSC (200 mg/kg) also decreased the volume of gastric secretion (approximately 2.2 mL) and gastric acid output (0.16 mEq/4 hrs). From these results, we suggest that DSC isolated from DA may be useful for the treatment and/or protection of gastritis and gastric ulcer.

关键词： Dipsacussaponin C Dipsacusasper Antioxidants Gastritis Gastric Ulcer

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韩国说唱歌手朴载相的《江南风》备受推崇(英文)

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大学英语 2013年第4期 49-49页

作者： joohee Cho 李英福州大学

When South Korean rapper PSY released his music video "Gangnam Style" months ago, he had no idea it would go so globally viral. YouTube has recorded more than 28 million hits3 and countless parody4 video clips5 have b... 详细信息

关键词：高校英语课外阅读阅读材料

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