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Intermediate-scale Analysis of Landscape Characteristics Affecting Edge Formation in Burned Forests in Samcheok,Korea

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Journal of Mountain Science 2014年第2期11卷 384-397页

作者： Sang-Woo lee Myoung-Soo WON joo-mee lee Hai-Gyoung KIM Department of Design Konkuk University Kwangjin-Gu Hwayang-DongSeoul 143-701 South Korea Division of Forest Disaster and Fire prevention Korea Forest Research Institute Graduate Program Department of Landscape Architecture & Urban Planning Texas A&M University College Station Yirakjae Landscape Studio Songdong-Gu Hongik-Dong 210Seoul 133-880 South Korea

Compared to burn interiors, edges exhibit distinct biotic and abiotic conditions that include microclimate, wind speed, sunlight levels, soil composition, moisture content, nutrient availability, population density, and species diversity. This study characterized the landscapes in which burned forest edges formed in Samcheok, Korea. Over the study area, 500-m2 grid cells were generated to capture landscape characteristics. Grid cells intersecting burn boundary lines were designated as edge, while cells without these lines were classified as the interior of burned areas. Topographic variables including slope, elevation, topographic wetness index, solar radiation index, and proportions of fuel and land use types within grid cells were computed in a geographical information system(GIS). Correlation analysis with modified t-test and regression tree analysis were performed to explore the influences of landscape variables on edge formation with avoiding spatial autocorrelation problems. The results indicated that edges formed at low elevations with mild slopes, high topographic wetness, and low solar radiation. Edges were unlikely to form in areas dominated by Japanese red pines at low elevations. Moreover, heterogeneous land use/cover types contributed significantly to edge formation. Different forest management strategies for different landscape conditions can be more effective for enhancing resilience of forests to fire. Reducing susceptible fuel types might be effective at low elevations, while enhancing forest heterogeneity might be more effective at high elevations.

关键词： Forest fire Modified t-test, Edge formation Fuel type Topographic characteristics

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pH-induced structural changes of surface immobilized poly (L-lysine) by two-dimensional (2D) infrared correlation study

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Chinese Chemical Letters 2015年第2期26卷 173-176页

作者： Eun joo Yoo Boknam Chae Young mee Jung Seung Woo lee School of Chemical Engineering Yeungnam University Pohang Accelerator Laboratory Department of Chemistry Kangwon National University

This paper reports the pH-induced structural changes in the surface immobilized poly（L-lysine）（PLL）***-dimensional（2D） correlation analysis was applied to the Fourier transform infrared（FTIR）spectra of the surface-immobilized PLL film to examine the spectral changes induced by the alternations of the protonation state of the amino group in the side *** spectral changes in the FTIR spectra of the PLL film were observed between pH 7 and *** decrease in the protonation state of the amino group in the side chain induced spectral changes in the amino group as well as conformational changes in the alky]group in the side *** pH 1-8,the spectral changes in the amino and alkyl groups in the side chain occurred before those of the amide group in the main chain of the surface immobilized PLL film.

关键词： Poly(L-lysine)(PLL) Surface-immobilized polypeptide FT-IR spectroscopy 2D correlation spectroscopy

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Interleukin-24 is correlated with differentiation and lymph node numbers in rectal cancer

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World Journal of Gastroenterology 2011年第9期17卷 1167-1173页

作者： Youngmin Choi mee-Sook Roh Young-Seoub Hong Hyung-Sik lee Won-joo Hur Department of Radiation Oncology Dong-A University School of Medicine Department of Pathology Dong-A University School of Medicine Department of Preventive Medicine Dong-A University School of Medicine

AIM:To assess the significance of interleukin(IL)-24 and vascular endothelial growth factor(VEGF)expression in lymph-node-positive rectal cancer. METHODS:Between 1998 and 2005,90 rectal adenocarcinoma patients with lymph node involvement were *** patients received radical surgery and postoperative pelvic chemoradiotherapy of 50.4-54.0 *** of 5-fluorouracil and leucovorin or levamisole was given intravenously during the first and last week of radiotherapy,and then monthly for about 6 *** of IL-24 and VEGF was evaluated by immunohistochemical staining of surgical specimens, and their relations with patient characteristics and survival were *** median follow-up of surviving patients was 73 mo(range:52-122 mo). RESULTS:IL-24 expression was found in 81 out of 90 patients;31 showed weak intensity and 50 showedstrong *** expression was found in 64 out of 90 *** and weak intensities of IL-24 expression were classified as negative expression for ***-24 expression was significantly reduced in poorly differentiated tumors in comparison with well or moderately differentiated tumors(P=0.004),N2b to earlier N stages(P=0.016),and stageⅢc to stageⅢ a orⅢb(P=0.028).The number of involved lymph nodes was also significantly reduced in IL-24-positive patients in comparison with IL-24-negative ones. There was no correlation between VEGF expression and patient *** of IL-24 and VEGF was not correlated with survival,but N stage and stages were significantly correlated with survival. CONCLUSION:IL-24 expression was significantly correlated with histological differentiation,and inversely correlated with the degree of lymph node involvement in stageⅢrectal cancer.

关键词： Interleukin-24 Rectal cancer Lymph node Histological differentiation Vascular endothelial growth factor

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Synchronous triple occurrence of MALT lymphoma, schwannoma, and adenocarcinoma of the stomach

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World Journal of Gastroenterology 2017年第22期23卷 4127-4131页

作者： Kyeong W Choi mee joo Han S Kim Woo Y lee Department of Surgery Seoul Paik Hospital Inje University College of Medicine Department of Pathology Ilsan Paik Hospital Inje University College of Medicine

We present a case of a 56-year-old man with 3 synchronous gastric tumors. The patient presented with melena, and 3 gastric abnormalities were detected on gastroduodenoscopic examination, including a small ulcerative lesion in the gastric antrum, a submucosal mass in the gastric body, and severe erosion in the fundus. Histological examination of biopsy samples yielded respective diagnoses of gastric adenocarcinoma, gastritis, and mucosa-associated lymphoid tissue(MALT) lymphoma. The patient first received medication to eradicate any underlying Helicobacter pylori infection, which might have been a cause of the MALT lymphoma. Four weeks later, after examination of repeat biopsy samples revealed that the MALT lymphoma had resolved, the patient underwent subtotal gastrectomy. Further histological examination of resected tissue confirmed the antrum lesion as adenocarcinoma and the body lesion as schwannoma. To our knowledge, this is the first reported case of synchronous triple primary gastric adenocarcinoma, MALT lymphoma, and schwannoma.

关键词： Gastric cancer Synchronous Mucosa-associated lymphoid tissue lymphoma Schwannoma Triple

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Systematic review on the surgical treatment for T1 gallbladder cancer

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World Journal of Gastroenterology 2011年第2期17卷 174-180页

作者： Seung Eun lee Jin-Young Jang Chang-Sup Lim mee joo Kang Sun-Whe Kim Department of Surgery Chung-Ang University College of Medicine Department of Surgery Seoul National University College of Medicine

AIM:To evaluate the efficacy of simple and extended cholecystectomy for mucosa(T1a) or muscularis(T1b) gallbladder(GB) cancer. METHODS:Original studies on simple and extended cholecystectomy for T1a or T1b GB cancer were searched from MEDLINE(PubMed) ,Cochrane Library,EMBase,and CancerLit using the search terms of GB,cancer/carcinoma/tumor/neoplasm. RESULTS:Twenty-nine out of the 2312 potentially relevant publications met the eligibility *** the 1266 patients with GB cancer included in the publications,706(55.8%) and 560(44.2%) had T1a and T1b GB cancer,*** cholecystectomy for T1a and T1b GB cancer was performed in 590(83.6%) and 375(67.0%) patients,respectively(P<0.01) .In most series,the treatment of choice was simple cholecystectomy for T1a GB cancer patients with a 5-year survival rate of 100%.Lymph node metastasis was detected in 10.9% of the T1b GB cancer patients and in 1.8%of the T1a GB cancer patients,respectively(P<0.01) .Eight patients(1.1%) with T1a GB cancer and 52 patients(9.3%) with T1b GB cancer died of recurrent GB cancer(P<0.01) . CONCLUSION:Simple cholecystectomy represents the adequate treatment of T1a GB *** is no definite evidence that extended cholecystectomy is advantageous over simple cholecystectomy for T1b GB cancer.

关键词： Gallbladder Cancer Cholecystectomy Simple Extended

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Formulation of Reduction Rate for Ultimate Compressive Strength of Stiffened Panel Induced by Opening

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China Ocean Engineering 2014年第4期28卷 557-568页

作者：于昌利 lee joo-sung School of Naval Architecture and Ocean Engineering Harbin Institute of Technology School of Naval Architecture and Ocean Engineering University of Ulsan

The main objective of this study is to numerically investigate the characteristics of ultimate compressive strength of stiffened panels with opening and also to fit the design-oriented formulae. For this purpose, three series of well executed experimental data on longitudinally stiffened steel plates with and without opening subjected to the uniform axial in-pane load which is carried out to study the buckling and post-buckling up to the final failure are chosen. Also, a nonlinear finite element method capable of efficiently analyzing the large elasto-plastic deflection behavior of stiffened panels is developed and used for simulation. The feasibility of the present simulation process is confirmed by a good agreement with the experimental results. More case studies are developed employing the simulation process to analyze the influence of various design variables on the reduction rate of ultimate strength of stiffened panel induced by opening. Based on the computed results, two design formulae are fitted and the accuracy of design formulae is studied. Furthermore, the viability of the design formulae for practical engineering is proved.

关键词： stiffened panel opening reduction rate non-linear analysis formulae fitting

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Stable carbon and nitrogen isotopic composition of gas hydrate-bearing sediment from Hydrate Ridge,Cascadia Margin

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Science China Earth Sciences 2006年第8期49卷 872-880页

作者： Young-joo lee Petroleum and Marine Resources Research Division Korea Institute of Geoscience and Mineral Resources Daejon 305-350South Korea

54 sediments were sampled at 5 sites, 1244, 1245, 1246,1250 and 1251 from ODPLeg 204, Hydrate Ridge, Cascadia Margin. The stable carbon and nitrogen isotopic composition,δ^(13)C of organic matter and δ^(15)N, have been used to characterize the depositional variationof sediments with gas hydrate bearing. Values of δ^(13)C of bulk organic matter range between-22.37 per thousand and -24.72 per thousand PDB, with a mean value of -23.54 ± 1.17 per thousandPDB; δ^(15)N of the same sedimentary samples range from 3.30 per thousand to 5.68 per thousand,with a mean value of 4.49 ± 1.19 per thousand; Values of C/N ratio range from 4.53 to 9.26, with amean value of 6.90 ± 2.37. The occurrence of gas hydrate changed the diagenetic evolution trend ofthe carbon and nitrogen in organic matter. The δ^(15)N and C/N ratio depletion suggest that thenitrogen fixation related with the bacteria/archaea maybe occurred in the sediments near thehydrate. The stable carbon and nitrogen isotopic composition could be used to evaluate thedepositional environment in the study area.

关键词： gas hydrate, carbon isotopes, nitrogen isotopes, C/N ratio, nitrogen fixation.

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Celecoxib attenuates 5-fluorouracil-induced apoptosis in HCT-15 and HT-29 human colon cancer cells

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World Journal of Gastroenterology 2007年第13期13卷 1947-1952页

作者： Yun Jeong Lim Jong Chul Rhee Young mee Bae Wan joo Chun Department of Internal Medicine Dongguk University International Hospital Dongguk University College of Medicine Goyang Korea Division of Gastroenterology Department of Internal Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea Department of Parasitology Seoul National University College of Medicine Seoul Korea Department of Pharmacology Kangwon National University College of Medicine Chuncheon Korea

AIM： To investigate the combined chemotherapeutic effects of celecoxib when used with 5-FU in vitro. METHODS： Two human colon cancer cell lines （HCT-15 and HT-29） were treated with 5-FU and celecoxib, alone and in combination. The effects of each drug were evaluated using the MTT （3-（4, 5-dimethylthiazol-2-yl）-2, 5-diphenyltetrazolium bromide） assay, flow cytometry, and western blotting. RESULTS： 5-FU and celecoxib showed a dosedependent cytotoxic effect. When treated with 10-3 mol/L 5-FU （IC50） and celecoxib with its concentration ranging from 10.8 mol/L to 10.4 mol/L of celecoxib, cells showed reduced cytotoxic effect than 5-FU （10.3 mol/L） alone. Flow cytometry showed that celecoxib attenuated 5-FU induced accumulation of cells at subG1 phase. Western blot analyses for caspase-3 and poly （ADP-ribose） polymerase （PARP） cleavage showed that celecoxib attenuated 5-FU induced apoptosis. Western blot analyses for cell cycle molecules showed that G2/M arrest might be possible cause of 5-FU induced apoptosis and celecoxib attenuated 5-FU induced apoptosis via blocking of cell cycle progression to the G2/M phase, causing an accumulation of cells at the GI/S phase. CONCLUSION： We found that celecoxib attenuated cytotoxic effect of 5-FU. Celecoxib might act via inhibition of cell cycle progression, thus preventing apoptosis induced by 5-FU.

关键词： Antagonism Celecoxib Colorectal neoplasms Fluorouracil

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SUMS OF DUAL TOEPLITZ PRODUCTS ON THE ORTHOGONAL COMPLEMENTS OF FOCK-SOBOLEV SPACES

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Acta Mathematica Scientia 2024年第3期44卷 810-822页

作者：陈泳 Young joo lee Department of Mathematics Hangzhou Normal UniversityHangzhou311121China Department of Mathematics Chonnam National UniversityGwangju61186Korea

We consider dual Toeplitz operators on the orthogonal complements of the FockSobolev spaces of all nonnegative real ***,for symbols in a certain class containing all bounded functions,we study the problem of when an operator which is finite sums of the dual Toeplitz products is compact or ***,for bounded symbols,we construct a symbol map and exhibit a short exact sequence associated with the C^(*)-algebra generated by all dual Toeplitz operators with bounded symbols.

关键词： dual Toeplitz operators Fock-Sobolev spaces symbol map

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Small but big leaps towards neuroglycomics:exploring N-glycome in the brain to advance the understanding of brain development and function

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Neural Regeneration Research 2024年第3期19卷 489-490页

作者： Boyoung lee Hyun joo An Center for Cognition and Sociality Institute for Basic Science(IBS)DaejeonSouth Korea Asia-Pacific Glycomics Reference Site DaejeonSouth Korea Graduate School of Analytical Science&Technology Chungnam National UniversityDaejeonSouth Korea

Glycosylation is a process that involves the addition of sugar moieties or glycans to different types of molecules,including proteins,lipids,and nucleic *** these,protein glycosylation is one of the most prevalent forms of post-translational modification,playing a crucial role in biological *** more than ten monosaccharides identified within mammalian brain cells and more than 1×1012 possible combinations,the heterogeneity of glycosylation is extensive(Conroy et al.,2021).The diversity of glycans and the complexity of their structures allow for a wide range of protein functions.N-glycans are one of the most abundant forms of glycans and are involved in various cellular functions.N-glycans can be added to proteins at specific sequons,Asn-X-Ser/Thr,and are classified into three main types in mature glycoproteins:high mannose,complex,and *** mannose N-glycans consist of 5-9 mannose residues linked to a chitobiose core and undergo processing into complex or hybrid forms in the Golgi apparatus(Varki et al.,2017).Complex N-glycans are more diverse and contain various branched structures such as antennae with fucose,galactose,and sialic acid *** N-glycans contain one or more complex branches in conjunction with an oligomannose branch(Fisher and Ungar,2016).Understanding the specific functions of these different types of N-glycans in protein regulation,folding,and function is an active area of research in the life sciences,including glycobiology.

关键词： functions function apparatus

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