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Journal of Integrative Plant Biology 2022年第3期64卷 625-631页

作者： Min Yong ahn Dong Hye Seo Woo Taek Kim Department of Systems Biology Division of Life ScienceYonsei UniversitySeoul 03722Korea Institute of Life Science and Biotechnology Yonsei UniversitySeoul 03722Korea

The mechanism regulating proteasomal activity under proteotoxic stress conditions remains ***,we showed that arsenite-induced proteotoxic stress resulted in upregulation of Arabidopsis homologous PUB22 and PUB23 U-boxE3 ubiquitin ligases and that pub22 pub23 double mutants displayed arsenite-insensitive seed germination and root growth ***22/PUB23 downregulated 26 S proteasome activity by promoting the dissociation of the 19 S regulatory particle from the holo-proteasome complex,resulting in intracellular accumulation of UbG76 VGFP,an artificial substrate of the proteasome complex,and insoluble poly-ubiquitinated *** results suggest that PUB22/PUB23 play a critical role in arsenite-induced proteotoxic stress response via negative regulation of 26 S proteasome integrity.

关键词： Arabidopsis thaliana proteotoxic stress sodium arsenite U-box E3 ligases PUB22/23 26S proteasome complex

Formic acid as an alternative reducing agent for the catalytic nitrate reduction in aqueous media

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Journal of Environmental Sciences 2013年第8期25卷 1696-1702页

作者： Eun-kyoung Choi Kuy-hyun Park Ho-bin Lee Misun Cho Samyoung ahn Department of Environmental Education Sunchon National University

Formic acid was used for the nitrate reduction as a reductant in the presence of Pd：Cu/γ-alumina catalysts. The surface characteristics of the bimetallic catalyst synthesized by wet impregnation were investigated by SEM, TEM-EDS. The metals were not distributed homogeneously on the surface of catalyst, although the total contents of both metals in particles agreed well with the theoretical values. Formic acid decomposition on the catalyst surface, its influence on solution pH and nitrate removal efficacy was investigated. The best removal of nitrate （50 ppm） was obtained under the condition of 0.75 g/L catalyst with Pd：Cu ratio （4：1） and two fold excess of formic acid. Formic acid decay patterns resembled those of nitrate removal, showing a linear relationship between kf （formic acid decay） and k （nitrate removal）. Negligible amount of ammonia was detected, and no nitrite was detected, possibly due to buffering effect of bicarbonate that is in situ produced by the decomposition of formic acid, and due to the sustained release of H2 gas.

关键词： formic acid catalytic nitrate reduction Pd:Cu/γ-alumina catalyst H2 supply

Postpartum hemophagocytic lymphohistiocytosis:A case report

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世界临床病例杂志 2023年第26期11卷 6183-6188页

作者： Ju Ho An Jung Hwan ahn Department of Emergency Medicine Ajou University School of MedicineSuwon 16499Gyeonggi-doSouth Korea

BACKGROUND Postpartum hemophagocytic lymphohistiocytosis(HLH)is a rare disease with unclear *** is a secondary HLH diagnosed using the pediatric diagnostic criteria;however,the clinical diagnosis of postpartum HLH remains ***,HLH may remain undiagnosed,leading to poor patient ***,improvements in the accuracy of postpartum HLH diagnoses and treatments are *** SUMMARY We report the case of a 40-year-old female with postpartum *** patient attended the postpartum care center for 3 wk after giving birth and underwent needle aspiration due to thyroid gland enlargement 11 d before an emergency department visit precipitated by fever and abdominal *** no abnormal emergency room findings were noted,the patient was discharged with a prescription for broad-spectrum *** days later,she returned to the emergency room in a hemodynamically unstable state and was admitted to the intensive care unit with suspected sepsis or hematologic *** patient was treated,without effect,for sepsis using broad-spectrum antibiotics,and for suspected hematologic disease with steroid ***,she died due to rapidly worsening *** Rapid recognition and appropriate treatment of postpartum HLH are needed to improve the prognosis.

关键词： Bone marrow Pregnancy Lymphohistiocytosis Infection Steroids Case report

Fabrication of SiC_p/AA5083 composite via friction stir welding

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中国有色金属学会会刊：英文版 2012年第S3期22卷 634-638页

作者： Byung-Wook ahn Don-hyun CHOI Yong-Hwan KIM Seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

Microstructure and mechanical properties of SiCp /AA5083 composite fabricated by friction stir welding (FSW) were *** influence of the number of FSW passes on the distribution of SiC particles and mechanical properties in the joint was *** one pass,the SiC particles were entangled in the upper side of the stir zone (SZ).However,the particle distribution became more uniform after two passes due to the repeated stirring of the *** the SiC particles facilitate the grain refinement in the SZ by the pinning effect,the particle including region has much smaller grain size than the SZ without SiC *** SiCp /AA5083 composite region exhibits a Vickers hardness of HV90,which is much higher than the value of HV80 in the SZ produced by FSW without SiC particles.

关键词： metal matrix composite SiC particle friction stir welding mechanical property

Unexpected Li displacement and suppressed phase transition enabling highly stabilized oxygen redox in P3-type Na layered oxide cathode

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Journal of Energy Chemistry 2023年第10期85卷 144-153,I0006页

作者： Myungeun Choi Hobin ahn hyunyoung Park Yongseok Lee Jinho ahn Bonyoung Ku Junseong Kim Wonseok Ko Jungmin Kang Jung-Keun Yoo Duho Kim jongsoon Kim Department of Energy Science Sungkyunkwan UniversitySuwon 16419Republic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwon 16419Republic of Korea Carbon Composites Department Korea Institute of Materials Science(KIMS)Changwon 51508Republic of Korea Department of Mechanical Engineering(Integrated Engineering Program) Kyung Hee University1732Deogyeong-daeroGiheung-guYongin-siGyeonggi-do 17104Republic of Korea Department of KHU-KIST Convergence Science and Technology Kyung Hee University23Kyunghee-daero Dongdaemun-guSeoul 02447Republic of Korea

Oxygen redox is considered a new paradigm for increasing the practical capacity and energy density of the layered oxide cathodes for Na-ion batteries. However, severe local structural changes and phase transitions during anionic redox reactions lead to poor electrochemical performance with sluggish ***, we propose a synergy of Li-Cu cations in harnessing the full potential of oxygen redox, through Li displacement and suppressed phase transition in P3-type layered oxide cathode. P3-type Na_(0.7)[Li_(0.1)Cu_(0.2)Mn_(0.7)]O_(2) cathode delivers a large specific capacity of ~212 mA h g^(-1)at 15 mA g^(-1). The discharge capacity is maintained up to ~90% of the initial capacity after 100 cycles, with stable occurrence of the oxygen redox in the high-voltage region. Through advanced experimental analyses and first-principles calculations, it is confirmed that a stepwise redox reaction based on Cu and O ions occurs for the charge-compensation mechanism upon charging. Based on a concrete understanding of the reaction mechanism, the Li displacement by the synergy of Li-Cu cations plays a crucial role in suppressing the structural change of the P3-type layered material under the oxygen redox reaction, and it is expected to be an effective strategy for stabilizing the oxygen redox in the layered oxides of Na-ion batteries.

关键词： Layered oxide cathode Oxygen redox reaction Structural stability Li displacement No phase transition

Computed tomography coronary angiography after excluding myocardial infarction:high-sensitivity troponin versus risk score-guided approach

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World Journal of Emergency Medicine 2023年第6期14卷 428-433页

作者： Won Jae Yoo Shin ahn Bora Chae Won Young Kim Department of Emergency Medicine Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505Republicof Korea

BACKGROUND:Patients with suspected acute coronary syndrome (ACS) in whom myocardial infarction has been ruled out are still at risk of having obstructive coronary artery disease (CAD).This rate is higher among patients with intermediate high-sensitivity troponin I (hsTnI) concentrations (5 ng/L to 99th percentile) than low concentrations (<5 ng/L).Therefore,an intermediate concentration has been suggested as a candidate for downstream investigation with computed tomography coronary angiography(CTCA).We tried to compare the HEART score-guided ***-guided approach for identifying obstructive ***:From a prospective cohort study of patients presenting to the emergency department with suspected ACS,433 patients without elevated hsTnI who also underwent CTCA were selected and *** performances of hsTnI concentration and HEART score were compared using sensitivity,specificity,positive predictive value (PPV),and negative predictive value (NPV).RESULTS:Overall,120 (27.7%) patients had obstructive *** with intermediate hsTnI concentrations were more likely to have obstructive CAD than those with low hsTnI concentrations(40.0%vs.18.1%);patients with non-low-risk HEART scores (≥4 points) were also more likely to have obstructive CAD than those with low-risk scores (0 to 3 points)(41.0%vs.7.6%).The HEART score had higher sensitivity and NPV for detecting obstructive CAD in each classification than hsTnI concentration (sensitivity:89.2%vs.63.3%;NPV:92.4%vs.81.9%,respectively).CONCLUSION:After excluding myocardial infarction in patients with suspected ACS,adding the HEART score for selecting candidates for CTCA could improve patient risk stratification more accurately than relying on hsTnI concentration.

关键词： Chest pain Coronary artery disease Acute coronary syndrome Troponin HEART score

Protein Tyrosine Phosphatase 1B Inhibitors from Plantago asiatica

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Chinese Herbal Medicines 2011年第2期3卷 136-139页

作者： LEE hyun-sun ahn jong-seog Korea Research Institute of Bioscience and Biotechnology

Objective To identify the active compounds for protein tyrosine phosphatase 1B(PTP1B) from the seeds of Plantago *** Bioassay-guided fractionation resulted in the isolation of iridoid glucosides(1-5) with PTP1B inhibitory *** Five compounds were identified as desacetylhookerioside(1),melittoside(2),geniposidic acid(3),10-O-acetyl-geniposidic acid(4),and alpinoside(5).Conclusion Isolated compounds 35 inhibit PTP1B with IC50 values ranged from(16.3 ± 1.1) to(19.8 ± 1.2) μmol/L.

关键词： alpinoside geniposidic acid iridoid glucosides Plantago asiatica protein tyrosine phosphatase 1B

Digital Vision Based Concrete Compressive Strength Evaluating Model Using Deep Convolutional Neural Network

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Computers, Materials & Continua 2019年第9期61卷 911-928页

作者： hyun Kyu Shin Yong Han ahn Sang Hyo Lee Ha Young Kim Architectural Engineering Hanyang UniversityERICAAnsan-si15588Korea School of Architecture and Architectural Engineering Hanyang UniversityERICAAnsan-si15588Korea Division of Architecture and Civil Engineering Kangwon National UniversitySamcheok-si25913Korea Graduate School of Information Yonsei UniversitySeoul-si03722Korea.

Compressive strength of concrete is a significant factor to assess building structure health and ***,various methods have been developed to evaluate the compressive strength of concrete ***,previous methods have several challenges in costly,time-consuming,and *** address these drawbacks,this paper proposed a digital vision based concrete compressive strength evaluating model using deep convolutional neural network(DCNN).The proposed model presented an alternative approach to evaluating the concrete strength and contributed to improving efficiency and *** model was developed with 4,000 digital images and 61,996 images extracted from video recordings collected from concrete *** experimental results indicated a root mean square error(RMSE)value of 3.56(MPa),demonstrating a strong feasibility that the proposed model can be utilized to predict the concrete strength with digital images of their surfaces and advantages to overcome the previous *** experiment contributed to provide the basis that could be extended to future research with image analysis technique and artificial neural network in the diagnosis of concrete building structures.

关键词： Concrete compressive strength deep learning deep convolutional neural network image-based evaluation building maintenance and management

Functional Materials and Innovative Strategies for Wearable Thermal Management Applications

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Nano-Micro Letters 2023年第9期15卷 562-603页

作者： Yeongju Jung Minwoo Kim Taegyeom Kim Jiyong ahn Jinwoo Lee Seung Hwan Ko Applied Nano and Thermal Science Lab Department of Mechanical EngineeringSeoul National University1 Gwanak-roGwanak-guSeoul 08826South Korea Department of Mechanical Roboticsand Energy EngineeringDongguk University30 Pildong-ro 1-gilJung-guSeoul 04620South Korea Institute of Advanced Machinery and Design(SNU-IAMD) Seoul National UniversityGwanak-roGwanak-guSeoul 08826South Korea Institute of Engineering Research Seoul National University1 Gwanak-roGwanak-guSeoul 08826South Korea

Thermal management is essential in our body as it affects various bodily functions,ranging from thermal discomfort to serious organ failures,as an example of the worst-case *** have been extensive studies about wearable materials and devices that augment thermoregulatory functionalities in our body,employing diverse materials and systematic approaches to attaining thermal *** paper reviews the recent progress of functional materials and devices that contribute to thermoregulatory wearables,particularly emphasizing the strategic methodology to regulate body *** exist several methods to promote personal thermal management in a wearable *** instance,we can impede heat transfer using a thermally insulating material with extremely low thermal conductivity or directly cool and heat the skin ***,we classify many studies into two branches,passive and active thermal management modes,which are further subdivided into specific *** from discussing the strategies and their mechanisms,we also identify the weaknesses of each strategy and scrutinize its potential direction that studies should follow to make substantial contributions to future thermal regulatory wearable industries.

关键词： Thermal management Passive heat transfer Active heat transfer Wearable materials Wearable device

Effect of Post-Rolling after ECAP on Superplastic Behavior of Commercial Al-Mg Alloy

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Journal of Rare Earths 2004年第Z2期22卷 53-56页

作者： Dong Hyuk Shin Byung Du ahn hyun Soo Woo Kyeom Kim Kyung-Tae Park Department of Metallurgy and Materials Science Hanyang UniversityAnsan 425-791Korea Department of Metallurgy and Materials ScienceHanyang UniversityAnsan 425-791Korea Department of Metallurgy and Materials ScienceHanyang UniversityAnsan 425-791Korea Department of Metallurgy and Materials ScienceHanyang UniversityAnsan 425-791Korea Division of Advanced Materials Science & EngineeringHanbat National UniversityTaejon 305-719Korea

A commercial Al-Mg alloy was subjected to equal channel angular pressing of 4 passes with and without postrolling, and the effects of post-rolling on the deformation characteristics of the alloy at 723 K were examined. Post-rolling was found to influence the deformation behavior significantly. The deformation behavior of the alloy processed only by equal channel angular pressing was characterized by (a) localized deformation indicated by severe surface prominence and depression, (b) the strain rate sensitivity of 0.33, and (c) moderate high strain rate superplastic elongations. By contrast, that of the alloy processed by equal channel angular pressing and post-rolling (70 % thickness reduction) was manifested by (a) uniform deformation associated with grain boundary sliding throughout the sample, (b) a sigmoidal behavior showing the strain rate sensitivity of 0.45 at the intermediate strain rates in the logarithmic stress-strain rate curve, and (c) very large high strain rate superplastic elongations.

关键词： high superplasticity equal channel angular pressing rolling deformation mechanisms rare earths