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Detection of large color variation in the potentially hazardous asteroid(297274) 1996 SK

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Research in Astronomy and Astrophysics 2014年第3期14卷 311-318页

作者： Chien-Hsien Lin Wing-Huen ip Zhong-Yi Lin Fumi Yoshida Yu-Chi Cheng Space Science Institute Macao University of Science and Technology Institute of Astronomy National Central University National Astronomical Observatory Osawa MitakaTokyo

Low-inclination near-earth asteroid （NEA）（297274） 1996 SK, which isalso classified as a potentially hazardous asteroid, has a highly eccentric orbit. Itwas studied by multi-wavelength photometry within the framework of an NEA colorsurvey at Lulin Observatory. Here, we report the finding of large color variationacross the surface of （297274） 1996 SK within one asteroidal rotation period of4.656 ± 0.122 hours and classify it as an S-type asteroid according to its averagecolors ofB - V = 0.767 ± 0.033, V - R = 0.482 ± 0.021, V - I = 0.801 ± 0.025and the corresponding relative reflectance spectrum. These results might be indica-tive of differential space weathering or compositional inhomogeneity in the surfacematerials.

关键词： minor planets, asteroids: individual: PHA (297274) techniques: photometric

An Intelligent Prediction Model for Target Protein Identification in Hepatic Carcinoma Using Novel Graph Theory and ANN Model

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Computer Modeling in Engineering & Sciences 2022年第10期133卷 31-46页

作者： G.Naveen Sundar Stalin Selvaraj D.Narmadha K.Martin Sagayam A.Amir Anton jone.Ayman A.Aly Dac-Nhuong Le Computer Science and Engineering Karunya Institute of Technology and SciencesCoimbatore641114India Centre for Nanotechnology&Advanced Biomaterials(CeNTAB) School of Chemical&BiotechnologySASTRA Deemed to be UniversityThanjavur613401India Department of ECE Karunya Institute of Technology and SciencesCoimbatore641114India Department of Mechanical Engineering College of EngineeringTaif UniversityTaif21944Saudi Arabia Institute of Research and Development Duy Tan UniversityDanang550000Vietnam Faculty of Information Technology Duy Tan UniversityDanang550000Vietnam

Hepatocellular carcinoma(HCC)is one major cause of cancer-related mortality around the ***,at advanced stages of HCC,systematic treatment options are currently *** a result,new pharmacological targetsmust be discovered regularly,and then tailored medicines against HCC must be *** this research,we used biomarkers of HCC to collect the protein interaction network related to ***,DC(Degree Centrality)was employed to assess the importance of each *** an improved Graph Coloring algorithm was used to rank the target proteins according to the interaction with the primary target protein after assessing the top ranked proteins related to ***,physio-chemical proteins are used to evaluate the outcome of the top ranked *** proposed graph theory and machine learning techniques have been compared with six existing *** the proposed approach,16 proteins have been identified as potential therapeutic drug targets for Hepatic *** is observable that the proposed method gives remarkable performance than the existing centrality measures in terms of Accuracy,Precision,Recall,Sensitivity,Specificity and F-measure.

关键词： Drug target detection hepatic carcinoma degree centrality graph coloring artificial neural network model

Photosynthetic and Molecular Markers of CO_2-mediated Photosynthetic Downregulation in Nodulated Alfalfa

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Journal of Integrative Plant Biology 2013年第8期55卷 721-734页

作者： Alvaro Sanz-Sez Gorka Erice Iker Aranjuelo Ricardo Aroca Juan Manuel Ruíz-Lozano jone.Aguirreolea Juan Jos Irigoyen Manuel Sanchez-Diaz Department of Plant Biology University of NavarraPamplonaE-31008Spain Department of Plant Biology University of BarcelonaBarcelonaE-8028Spain Department of Plant Biology University of Illinois at Urbana-Champaign61801USA Agrobiotechnology Institute Public University of NavarraMutilva BajaE-31192Spain Department of Soil Microbiology and Symbiotic Systems Zaidin Experimental Station(CSIC)GranadaE-18008.Spain

Elevated CO2 leads to a decrease in potential net photosynthesis in long-term experiments and thus to a reduction in potential growth. This process is known as photosynthetic downregulation. There is no agreement on the definition of which parameters are the most sensitive for detecting CO2 acclimation. In order to investigate the most sensitive photosynthetic and molecular markers of CO2 acclimation, the effects of elevated CO2, and associated elevated temperature were analyzed in alfalfa plants inoculated with different Sinorhizobium meliloti strains. Plants （Medicago sativa L. cv. Aragon） were grown in summer or autumn in temperature gradient greenhouses （TGG）. At the end of the experiment, all plants showed acclimation in both seasons, especially under elevated summer temperatures. This was probably due to the lower nitrogen （N） availability caused by decreased N2-fixation under higher temperatures. Photosynthesis measured at growth CO2 concentration, rubisco in vitro activity and maximum rate of carboxylation were the most sensitive parameters for detecting downregulation. Severe acclimation was also related with decreases in leaf nitrogen content associated with declines in rubisco content （large and small subunits） and activity that resulted in a drop in photosynthesis. Despite the sensitivity of rubisco content as a marker of acclimation, it was not coordinated with gene expression, possibly due to a lag between gene transcription and protein translation.

关键词： Carbon dioxide Medicago sativa (alfalfa) photosynthetic downregulation RbcL and RbcS Sinorhizobium meliloti.

Lunar potassium distribution:Results from Chang'E-1 gamma ray spectrometer

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Science China(Physics,Mechanics & Astronomy) 2011年第11期54卷 2083-2090页

作者： ZHU Meng-Hua MA Tao CHANG Jin TANG ZeSheng ip Wing-Huen XU AoAo Space Exploration Laboratory Macao University of Science and Technology Avenida Wai Long Taipa Macao China Purple Mountain Observatory Chinese Academy of Sciences 2 West Beijing Road Nanjing 210008 China

The global map of potassium is represented in this paper from Chang'E-1 (CE-1) Gamma-ray Spectrometer (CGRS) for its one-year *** a linear relationship between net count rate and its abundance,the average potassium abundance of individual landing sites is used as ground-truth for the calibration to derive the global map of absolute *** CGRS spectra have a lower signal-to-noise ratio,the translated map still keeps relative *** calculated from Apollo,Lunar Prospector,and Kaguya,global potassium map from CGRS shows high concentrations on the lunar nearside and secondary concentrations located in the South Pole-Aitken (SPA) basin on the *** comparison with Lunar Prospector potassium map shows a good correlation,though abundances on the highlands of the farside are much lower than that of Lunar *** the footprint of CGRS measurements is larger than the sampling radius of each landing site,the calibrated map shows a larger variation range of the scale than that of Lunar Prospector,which was derived using theoretical calculation;namely,the calibrated map has higher values in the areas with high concentration while having lower values for the areas with lower ***,the derived potassium map is more consistent with the lunar sample data than that of Lunar Prospector.

关键词： Chang'E-1 gamma-ray spectrometer potassium distribution empirical calibration

Preface: The Chang'e-3 lander and rover mission to the Moon

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Research in Astronomy and Astrophysics 2014年第12期14卷 1511-1513页

作者： Wing-Huen ip Jun Yan Chun-Lai Li Zi-Yuan Ouyang Institute of Astronomy National Central University National Astronomical Observatories Chinese Academy of Sciences

The Chang＇e-3 （CE-3） lander and rover mission to the Moon was an in- termediate step in China＇s lunar exploration program, which will be followed by a sample return mission. The lander was equipped with a number of remote-sensing instruments including a pair of cameras （Landing Camera and Terrain Camera） for recording the landing process and surveying terrain, an extreme ultraviolet camera for monitoring activities in the Earth＇s plasmasphere, and a first-ever Moon-based ultravi- olet telescope for astronomical observations. The Yutu rover successfully carried out close-up observations with the Panoramic Camera, mineralogical investigations with the VIS-NIR Imaging Spectrometer, study of elemental abundances with the Active Particle-induced X-ray Spectrometer, and pioneering measurements of the lunar sub- surface with Lunar Penetrating Radar. This special issue provides a collection of key information on the instrumental designs, calibration methods and data processing pro- cedures used by these experiments with a perspective of facilitating further analyses of scientific data from CE-3 in preparation for future missions.

关键词： Chang'e-3 - Moon lander - rover - radar - lunar telescope

Risk of ischaemic and haemorrhagic stroke in Chinese undergoing percutaneous coronary intervention treated with potent P2Y12 inhibitor versus clopidogrel

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Stroke & Vascular Neurology 2022年第4期7卷 310-318,I0015-I0019页

作者： Andrew Kei-Yan Ng Pauline Yeung Ng April ip Kui Kai Lau Chung-Wah Siu Cardiac Medical Unit Grantham HospitalHong KongHong Kong Department of Adult Intensive Care Queen Mary HospitalHong KongHong Kong Department of Medicine The University of Hong KongHong KongHong Kong The State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong KongHong Kong

Background Stroke after acute coronary syndrome(ACS)can be *** is uncertain whether the risks of ischaemic stroke or intracranial haemorrhage(ICH)are associated with different choices of P2Y12 inhibitors(potent P2Y12 inhibitors such as ticagrelor and prasugrel vs clopidogrel).Even though East Asians are known to have different thrombotic and haemorrhagic profiles from Caucasians,data on Chinese patients are *** This was a retrospective cohort study conducting in Chinese patients with ACS who underwent first-ever percutaneous coronary intervention from 14 hospitals in Hong Kong between 2010 and *** primary efficacy endpoint was ischaemic *** secondary efficacy endpoint was a composite outcome of thrombotic events including all-cause mortality,non-fatal myocardial infarction and ischaemic *** primary safety endpoint was *** secondary safety endpoint was a composite of major bleeding *** After adjustment of baseline characteristics by 1:1 propensity score matching,a total of 6220 patients(3110 on each group)were *** with clopidogrel,potent P2Y12 inhibitors were associated with a lower risk of ischaemic stroke(HR 0.57;95%CI 0.37 to 0.87;p=0.008)and a lower risk of thrombotic events(HR 0.77;95%CI 0.66 to 0.90;p=0.001).Potent P2Y12 inhibitor was associated with similar risk of ICH(HR 0.65;95%CI 0.34 to 1.25,p=0.20)and major bleeding(HR 0.83;95%CI 0.68 to 1.01,p=0.069).Conclusions Potent P2Y12 inhibitors were associated with a lower adjusted risk of ischaemic stroke and thrombotic events,compared with *** risks of ICH and major bleeding were similar.

关键词： P2Y12 coronary haemorrhagic

A Functional Framework for Integrating eCRM with Workflow Management Based on Customer Value

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Tsinghua Science and Technology 2006年第1期11卷 65-73页

作者： W. H. ip 陈伯成 Henry C. W. Lau 梁冰 Department of Industrial and Systems Engineering Hong Kong Polytechnic University Hunghom Hong Kong China Department of Industrial and Systems Engineering Hong Kong Polytechnic UniversityHunghom Hong Kong China School of Economics and Management Tsinghua UniversityBeijing 100084 China

eCRM ties customer relationship management with e-business. Very often, eCRM is interfaced with other information systems to form a seamless integration and interchange of information both inside and outside an organization--a work flow management system. This integration of business partners, suppliers, and customers is essential in this global competitive market environment. An effective infrastructure and hence an appropriate framework are required to provide the information exchange and data analysis between eCRM and work flow management. This paper proposes a functional framework of eCRM based on customer value to realize the win-win strategy for both the companies and their customers. Moreover, a workflow management system also forms an integral part of this total solution to facilitate the implementation of a supply chain or extended enterprise.

关键词： customer relations management work flow management information system supply chain

Health correlates, addictive behaviors, and peer victimization among adolescents in China

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World Journal of Pediatrics 2018年第5期14卷 454-460页

作者： Qi-Qi Chen Meng-Tong Chen Yu-Hong Zhu Ko Ling Chan Patrick ip Department of Applied Social Sciences The Hong Kong Polytechnic UniversityHung HomHong KongChina Department of Social Work Renmin University of ChinaHaidianBeijingChina Department of Pediatrics and Adolescent Medicine The University of Hong KongPokfulamHong KongChina

Background Peer victimization has been recognized as a common social problem affecting children and adolescents in all parts of the world. This study aims to examine the prevalence of different types of peer victimization and to evaluate the associations between peer victimization and health correlates. Methods Using a large population sample of 18,341 adolescents aged 15–17 years from 6 cities in China, this study esti-mated the prevalence of different types of peer victimization, addictive behaviors, and health-related variables with self-administrated questionnaires. A three-phase logistical regression analysis was conducted to investigate the associations between peer victimization and addictive behaviors as well as health-related factors among adolescents. Results A total of 42.9% of the surveyed Chinese adolescents have been bullied by peers, with boys reporting higher rate on overt victimization (36.9%) and girls on relational forms (33.9%). School environment (34.7%) was the most frequent scene of peer violence, followed by neighborhood, family, and internet. Addictive behaviors except substance abuse were found related to higher possibility of peer victimization (aOR 1.21–1.73, P<0.001). Peer victimization was significantly associated with more depressive symptoms, post-traumatic stress disorder symptoms, and suicide ideation and deliberate self-harm (aOR 1.05–2.27, P<0.001), and poorer self-esteem and health-related quality of life (aOR 0.95–0.97, P<0.001). Conclusion Possible explanations of the associations found in this study are discussed and implications for future services are raised.

关键词： Addictive behavior Adolescent Health Peer victimization

Soft Computing Based Procurement Planning of Time-variable Demand in Manufacturing Systems

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International Journal of Automation and computing 2007年第1期4卷 80-87页

作者： Kai Leung Yung Wai Hung ip Ding-Wei Wang Department of Industrial and Systems Engineering Hong Kong Polytechnic University Hung Horn Kowloon Hong Kong PRC School of Information Science and Engineering Northeastern University Shenyang 110004 PRC

Procurement planning with discrete time varying demand is an important problem in Enterprise Resource Planning （ERP）. It can be described using the non-analytic mathematical programming model proposed in this paper. To solve the model we propose to use a fuzzy decision embedded genetic algorithm. The algorithm adopts an order strategy selection to simplify the original real optimization problem into binary ones. Then, a fuzzy decision quantification method is used to quantify experience from planning experts. Thus, decision rules can easily be embedded in the computation of genetic operations. This approach is applied to purchase planning problem in a practical machine tool works, where satisfactory results have been achieved.

关键词： Purchase planning Enterprise Resource Planning (ERP) soft computing genetic algorithm fuzzy decision inventory control.