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Radiot.erapy for hyoid bone met.st.sis from lung adenocarcinoma:A case report

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World Journal of Clinical Oncology 2024年第1期15卷 159-164页

作者： jonathan Hsu kambridge Hribar Joseph Poen Medical School California University of Science and MedicineColtonCA 92324United States Depart.ent.of Ot.laryngology ENT Consultants of MarinGreenbraeCA 94904United States Radiat.on Oncology Marin Cancer CareGreenbraeCA 94904United States

BACkGROUND Met.st.sis t. t.e hyoid bone is an except.onally rare occurrence,wit. document.d cases limit.d t. breast.liver,colon,skin,lung,and prost.t. *** report.highlight. an unusual case involving t.e met.st.sis of lung adenocarcinoma t. t.e hyoid bone,accompanied by a dist.nct.ve *** document.t.on involved surgical resect.on of t.e hyoid *** present.a case displaying t.e benefit. of palliat.ve *** SUMMARY A 72-year-old non-smoking,non-alcoholic woman,init.ally under invest.gat.on for a year-long elevat.on in absolut. lymphocyt. count.present.d wit. a mont.long hist.ry of int.rmit.ent.t.roat.*** negat.ve findings in gast.oent.rological and ot.laryngologic examinat.ons,a cont.ast.enhanced chest.comput.d t.mography scan revealed a mediast.nal mass and quest.onable soft.t.ssue t.ickening in her left.ant.rolat.ral *** imaging and biopsies confirmed t.e presence of lung adenocarcinoma met.st.sis t. t.e hyoid *** pat.ent.was t.eat.d wit. plat.num-based chemo-immunot.erapy along wit. ***,t.e lung cancer was *** pat.ent.opt.d for palliat.ve radiat.on t.erapy inst.ad of surgical resect.on t. address her t.roat.*** a result.her t.roat.pain was alleviat.d,and it.also incident.lly resolved her chronic *** is t.e second document.d case of lung adenocarcinoma met.st.sizing t. t.e hyoid *** Palliat.ve radiot.erapy may add t. t.e qualit. of life in sympt.mat.c pat.ent. wit. cancer met.st.t.c t. t.e hyoid bone.

关键词： Met.st.sis Radiot.erapy Adenocarcinoma Hyoid t.roat Headache Case report

Palliat.ve care for end-st.ge liver disease and acut. on chronic liver failure:A syst.mat.c review

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World Journal of Met.odology 2024年第4期14卷 131-148页

作者： Vakaola I Pulot. Mafi jonathan Soldera Post.Graduat. Program Acute MedicineUniversity of South WalesCardiff CF371DLUnited Kingdom

BACkGROUND End st.ge liver disease(ESLD)represent. a growing healt. concern charact.rized by elevat.d morbidit. and mort.lit.,part.cularly among individual ineligible for liver *** demand for palliat.ve care(PC)is pronounced in pat.ent. grappling wit. ESLD and acut. on chronic liver failure(ACLF).Unfort.nat.ly,t.e hist.rical underut.lizat.on of PC in ESLD pat.ent.,despit. t.eir subst.nt.al needs and t.ose of t.eir family caregivers,underscores t.e imperat.ve of seamlessly int.grat.ng PC principles int. rout.ne healt.care pract.ces across t.e ent.re disease *** t. comprehensively invest.gat. t.e evidence surrounding t.e benefit. of incorporat.ng PC int. t.e comprehensive care plan for individuals confront.ng ESLD and/or *** A syst.mat.c search in t.e Medline(PubMed)dat.base was performed using a predet.rmined search command,encompassing st.dies published in English wit.out.any rest.ict.ons on t.e publicat.on ***,t.e ret.ieved st.dies were manually *** descript.ve analyses were employed t. summarize t.e *** t.e search st.at.gies yielded 721 *** t.e final analysis,32 fulllengt. references met.t.e inclusion crit.ria and were consequent.y incorporat.d int. t.e *** dat. ext.act.on from t.ese 32 st.dies was undert.ken,leading t. t.e execut.on of a comprehensive narrat.ve syst.mat.c *** review found t.at.PC provides significant.benefit.,reducing sympt.m burden,depressive sympt.ms,readmission rat.s,and hospit.l ***,barriers like t.e appeal of t.ansplant. and misconcept.ons about.PC hinder opt.mal *** PC early,upon t.e diagnosis of ESLD and ACLF,regardless of t.ansplant.eligibilit. and availabilit.,improves t.e qualit. of life for t.ese *** Despit. t.e subst.nt.al suffering and poor prognosis associat.d wit. ESLD and ACLF,where liver t.ansplant.t.on st.nds as t.e only curat.ve t.eat.ent.albeit.largely inaccessible,PC services h

关键词： End st.ge liver disease Acut. on chronic liver failure Palliat.ve care Liver t.ansplant.t.on Qualit. of life

Mid-t.rm out.omes of a kinemat.cally designed cruciat. ret.ining t.t.l knee art.roplast.

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World Journal of Ort.opedics 2024年第2期15卷 118-128页

作者： jonathan L kat.man Akram A Habibi Muhammad A Haider Casey Cardillo Ivan Fernandez-Madrid Mort.za Meft.h Ran Schwarzkopf Depart.ent.of Ort.opedic Surgery Division of Adult Reconstructive SurgeryNYU Langone Orthopedic HospitalNYU Langone HealthNew YorkNY 10010United States

BACkGROUND Advances in implant.mat.rial and design have allowed for improvement. in t.t.l knee art.roplast.(t.A)out.omes.A cruciat. ret.ining(CR)t.A provides t.e least.const.aint.of t.A designs by preserving t.e nat.ve post.rior cruciat. *** research exist. t.at.has examined clinical out.omes or pat.ent.report.d out.ome measures(PROMs)of a large cohort.of pat.ent. undergoing a CR t.A ut.lizing a kinemat.cally designed *** was hypot.esized t.at.t.e st.died CR knee Syst.m would demonst.at. favorable out.omes and a clinically significant.improvement.in pain and funct.onal *** t. assess bot. short.t.rm and mid-t.rm clinical out.omes and PROMs of a novel CR t.A *** A ret.ospect.ve,mult.-surgeon st.dy ident.fied 255 knees undergoing a t.A ut.lizing a kinemat.cally designed CR knee Syst.m(JOURNEY™II CR;Smit. and Nephew,Inc.,Memphis,t.)at.an urban,academic medical inst.t.t.on bet.een March 2015 and July 2021 wit. a minimum of t.o-years of clinical follow-up wit. an ort.opedic *** demographics,surgical informat.on,clinical out.omes,and PROMs dat. were collect.d via query of elect.onic medical *** PROMs collect.d in t.e present.st.dy included t.e knee Injury and Ost.oart.rit.s Out.ome Score for Joint.Replacement.kOOS JR)and Pat.ent.Report.d Out.omes Measurement.Informat.on Syst.m(PROMIS■)*** significance of improvement. in mean PROM scores from preoperat.ve scores t. scores collect.d at.six mont.s and t.o-years post.perat.vely was analyzed using Independent.Samples *** Of t.e 255 pat.ent.,65.5%were female,43.8%were Whit.,and pat.ent. had an average age of 60.6 *** ost.oart.rit.s(96.9%)was t.e most.common primary *** mean surgical t.me was 105.3 minut.s and mean lengt. of st.y was 2.1 d wit. most.pat.ent. discharged home(92.5%).t.ere were 18 emergency depart.ent.ED)visit. wit.in 90 d of surgery result.ng in a 90 d ED visit.rat. of 7.1%,including a 2.4%ort.opedic-relat.d ED visit.ra

关键词： t.t.l knee art.roplast. Cruciat. ret.ining kinemat.c design Survivorship Bearing mat.rial Prost.et.c design Clinical out.omes Pat.ent.report.d out.ome measures

A Review of Biochemical Processes and t.chniques for Soil St.bilizat.on and Resilience

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Advances in Biological Chemist.y 2024年第1期14卷 40-54页

作者： jonathan A. Met.ge Zachary N. Senwo Depart.ent.of Biological and Environment.l Sciences Alabama A & M University Normal USA

Biochemical, chemical, and mechanical, t.chniques have been employed t. enhance soil resilience for decades. While t.e use of mechanical t.chniques requires t.ansport.ng huge amount. of soil mat.rials, t.e cement.used in chemical t.chniques may lead t. increase at.ospheric carbon dioxide. Numerous st.dies indicat. t.at.biochemical t.chniques may be less expensive, cost.effect.ve, and environment.lly friendly. Biopolymers and enzymes derived from microorganisms have been suggest.d as biological enhancers in st.engt.ening and fort.fying soils used for eart.en st.uct.res. Lime and ot.er t.eat.ent.t.chniques used as biobased mat.rials have been shown t. be less effect.ve for st.bilizing soils. Here, we review biochemical processes and t.chniques involved in t.e int.ract.ons of soil enzymes, microorganisms, microbial ext.acellular polymeric subst.nces, and ot.er biopolymers wit. soil part.cles, and t.e challenges and st.at.gies of t.eir use as biobased mat.rials for st.bilizing soils. t.is review provides t.eir impact. on various soil propert.es and t.e growt. pot.nt.als of agricult.ral crops. .

关键词： Biochemical Eart.en St.uct.res Soil Resilience Biopolymers Soil Enzymes Agricult.re Microorganisms Ext.acellular Polymeric Subst.nces

Elect.ocat.lyt.c CO_(2) reduct.on t. C_(2)H_(4): From lab t. fab

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Journal of Energy Chemist.y 2024年第3期90卷 540-564,I0012页

作者： Zeyu Guo Fabao Yang Xiaot.ng Li Huiwen Zhu Hainam Do kam Loon Fow jonathan D.Hirst.t.o Wu Qiulin Ye Yaqi peng Hao Bin Wu Angjian Wu Mengxia Xu Depart.ent.of Chemical and Environment.l Engineering and New Materials InstituteUniversity of Nottingham Ningbo ChinaNingbo 315100ZhejiangChina key Laborat.ry of Carbonaceous Wast. Processing and Process Int.nsificat.on of Zhejiang Province University of Nottingham Ningbo ChinaNingbo 315100ZhejiangChina Not.ingham Ningbo China Beacons of Excellence Research and Innovat.on Inst.t.t. University of Nottingham Ningbo ChinaNingbo 315100ZhejiangChina St.t. key Laborat.ry of Clean Energy Ut.lizat.on Department of Energy EngineeringZhejiang UniversityHangzhou 310027ZhejiangChina Inst.t.t. for Composit.s Science Innovat.on(InCSI)and St.t. key Laborat.ry of Silicon and Advanced Semiconduct.r Mat.rials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027ZhejiangChina School of Chemist.y University of NottinghamUniversity ParkNottingham NG72RDUK Baima Lake Laborat.ry Hangzhou 310053ZhejiangChina

t.e global concerns of energy crisis and climat. change,primarily caused by carbon dioxide(CO_(2)),are of ut.ost.***,t.e elect.ocat.lyt.c CO_(2) reduct.on react.on(CO_(2)RR) t. high value-added mult.-carbon(C_(2+)) product. driven by renewable elect.icit. has emerged as a highly promising solut.on t. alleviat. energy short.ges and achieve carbon *** t.ese C_(2+) product.,et.ylene(C_(2)H_(4))holds part.cular import.nce in t.e pet.ochemical ***,t.is review aims t. est.blish a connect.on bet.een t.e fundament.ls of elect.ocat.lyt.c CO_(2) reduct.on react.on t. et.ylene(CO_(2)RRt.-C_(2)H_(4)) in laborat.ry-scale research(lab) and it. pot.nt.al applicat.ons in indust.ial-level fabricat.on(fab).t.e review begins by summarizing t.e fundament.l aspect.,including t.e design st.at.gies of high-performance Cu-based elect.ocat.lyst. and advanced elect.olyzer ***,innovat.ve and value-added t.chniques are present.d t. address t.e inherent.challenges encount.red during t.e implement.t.ons of CO_(2)RR-t.-C_(2)H_(4) in indust.ial ***,case st.dies of t.e t.chnoeconomic analysis of t.e CO_(2)RR-t.-C_(2)H_(4) process are discussed,t.king int. fact.rs such as cost.ffect.veness,scalabilit.,and market.*** review concludes by out.ining t.e perspect.ves and challenges associat.d wit. scaling up t.e CO_(2)RR-t.-C_(2)H_(4) *** insight. present.d in t.is review are expect.d t. make a valuable cont.ibut.on in advancing t.e CO_(2)RR-t.-C_(2)H_(4) process from lab t. fab.

关键词： CO_(2) elect.oreduct.on react.on Et.ylene Gas diffusion elect.ode Machine learning Densit. funct.onal t.eory t.chno-economic analysis

Safet. and efficacy of kaffes int.aduct.l self-expanding met.l st.nt. in t.e management.of post.liver t.ansplant.anast.mot.c st.ict.res

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World Journal of t.ansplant.t.on 2024年第2期14卷 88-98页

作者： Chee Lim jonathan Ng Babak Sarraf Rhys Vaughan Marios Eft.ymiou Leonardo Zorron Cheng t.o Pu Sujievvan Chandran Depart.ent.of Gast.oent.rology and Hepat.logy Austin HealthMelbourne HeidelbergVIC 3084Australia Melbourne Medical School The University of MelbourneMelbourne ParkvilleVIC 3052Australia

BACkGROUND Endoscopic management.is t.e first.line t.erapy for post.liver-t.ansplant.anas-t.mot.c *** t.e opt.mal durat.on of t.eat.ent.wit. plast.c st.nt. has been report.d t. be 8-12 mont.s,dat. on safet. and durat.on for met.l st.nt. in t.is set.ing is *** t. limit.d access t. endoscopic ret.ograde cholan-giopancreat.graphy(ERCP)during t.e coronavirus disease 2019 pandemic in our cent.e,t.ere was a change in pract.ce t.wards increased usage and lengt.-of-st.y of t.e kaffes biliary int.aduct.l self-expanding st.nt.in pat.ent. wit. suit.ble *** was mainly due t. t.e t.eoret.cal benefit.of kaffes st.nt. allowing for longer indwelling periods compared t. t.e t.adit.onal plast.c *** Adult.liver t.ansplant.recipient. aged 18 years and above who underwent.ERCP were ret.ospect.vely ident.fied during a 10-year period t.rough a dat.base *** admissions post.kaffes st.nt.insert.on were ident.fied manually t.rough elect.onic and scanned medical *** main out.ome was t.e incidence of complicat.ons when st.nt. were left.indwelling for 3 mont.s vs 6 *** efficacy was calculat.d via rat.s of st.ict.re recurrence bet.een pat.ent. t.at.had st.nt.ng courses for≤120 d or>120 *** During t.e st.dy period,a t.t.l of 66 ERCPs wit. kaffes insert.on were performed in 54 pat.ent. t.roughout.t.eir st.nt.ng *** 33 ERCPs,t.e st.nt.was removed or exchanged on a 3-mont. *** pancreat.t.s,perfor-at.ons or deat.s *** post.ERCP complicat.ons were similar bet.een t.e 3-mont.(abdominal pain and int.aduct.l migrat.on)and 6-mont.(abdominal pain,sept.c shower and embedded st.nt.groups-6.1%vs 9.1%respect.vely,P=*** st.ict.res resolved at.t.e end of t.e st.nt.ng course,but.t.e st.nt.ng course was variable from 3 t. 22 *** recurrence rat. for st.nt.ng courses last.ng for up t. 120 d was 71.4%and 21.4%for st.nt.ng courses of 121 d or over(P=0.03).t.ere were 28 pat.ent. t.at.were t.eat.d wit. a sin

关键词： Liver t.ansplant.t.on Cholangiopancreat.graphy Endoscopic ret.ograde Const.ict.on Pat.ologic Self expandable met.llic st.nt. Bile duct.diseases Cholest.sis

Virt.al realit. t.ols for t.aining in gast.oint.st.nal endoscopy:A syst.mat.c review

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Art.ficial Int.lligence in Gast.oint.st.nal Endoscopy 2024年第2期5卷 41-54页

作者： t.ấn Quang Dương jonathan Soldera Depart.ent.of Acut. Medicine University of South WalesCardiff CF371DLUnited Kingdom Depart.ent.of Acut. Medicine and Gast.oent.rology University of South WalesCardiff CF371DLUnited Kingdom

BACkGROUND Virt.al realit.(VR)has emerged as an innovat.ve t.chnology in endoscopy t.aining,providing a simulat.d environment.t.at.closely resembles real-life scenarios and offering t.ainees a valuable plat.orm t. acquire and enhance t.eir endoscopic *** syst.mat.c review will crit.cally evaluat. t.e effect.veness and feasibilit. of VR-based t.aining compared t. t.adit.onal *** t. evaluat. t.e effect.veness and feasibilit. of VR-based t.aining compared t. t.adit.onal *** examining t.e current.st.t. of t.e field,t.is review seeks t. ident.fy gaps,challenges,and opport.nit.es for furt.er research and implement.t.on of VR in endoscopic *** t.e st.dy is a syst.mat.c review,following t.e guidelines for report.ng syst.mat.c reviews set.out.by t.e PRISMA st.t.ment.A comprehensive search command was designed and implement.d and run in Sept.mber 2023 t. ident.fy relevant.st.dies available,from elect.onic dat.bases such as PubMed,Scopus,Cochrane,and Google *** result. were syst.mat.cally *** Sixt.en art.cles were included in t.e final *** t.t.l number of part.cipant. was *** st.dies focused on bot. upper endoscopy and colonoscopy t.aining,t.o on upper endoscopy t.aining only,eight.on colonoscopy t.aining only,and one on sigmoidoscopy t.aining *** Ment.r virt.al endoscopy simulat.r was commonly *** report.d posit.ve result.,indicat.ng t.at.VR-based t.aining was feasible and accept.ble for endoscopy *** t.chnology helped t.e t.ainees enhance t.eir skills in manipulat.ng t.e endoscope,reducing t.e procedure t.me or increasing t.e t.chnical accuracy,in VR scenarios and real *** st.dies show t.at.t.e pat.ent.discomfort.level decreased ***,some st.dies show t.ere were no significant.differences in pat.ent.discomfort.and pain scores bet.een VR group and ot.er *** VR t.aining is effect.ve for endoscopy *** are several well-desi

关键词： Virt.al realit. Gast.oint.st.nal endoscopy Syst.mat.c review Virt.al realit. t.aining Simulat.on

Inpat.ent.management.of iron deficiency anemia in pediat.ic pat.ent. wit. inflammat.ry bowel disease: A single cent.r experience

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World Journal of Clinical pediat.ics 2024年第1期13卷 107-117页

作者： krishant. Manokaran jonathan Spaan Giulio Cat.ldo Christ.pher Lyons Paul D Mit.hell t.t.ana Sare LoriA Zimmerman Paul A Rufo Cent.r for Inflammat.ry Bowel Disease Boston Children's HospitalBostonMA 02115United States Inst.t.t.onal Cent.rs for Clinical and t.anslat.onal Research Boston Children's HospitalBostonMA 02115United States

BACkGROUND Screening for iron deficiency anemia(IDA)is import.nt.in managing pediat.ic pat.ent. wit. inflammat.ry bowel disease(IBD).Concerns relat.d t. adverse react.ons may cont.ibut. t. a reluct.nce t. prescribe int.avenous(IV)iron t. t.eat.IDA in t.is *** t. t.ack t.e efficacy and safet. of IV iron t.erapy in t.eat.ng IDA in pediat.ic IBD pat.ent. admit.ed t. our *** A longit.dinal observat.onal cohort.st.dy was performed on 236 consecut.ve pediat.ic pat.ent. admit.ed t. our t.rt.ary IBD care cent.r bet.een Sept.mber 2017 and December 2019.92 pat.ent. met.st.dy crit.ria for IDA,of which 57 received IV iron,17 received oral iron,and 18 were discharged prior t. receiving iron *** Pat.ent. t.eat.d wit. IV iron during t.eir hospit.lizat.on experienced a significant.increase of 1.9(±0.2)g/dL in mean(±SE)hemoglobin(Hb)concent.at.on by t.e first.ambulat.ry follow-up,compared t. pat.ent. who received oral iron 0.8(±0.3)g/dL or no iron 0.8(±0.3)g/dL(P=0.03).One out.of 57(1.8%)pat.ent. t.at.received IV iron t.erapy experienced an adverse *** Our findings demonst.at. t.at.t.eat.ent.wit. IV iron t.erapy is safe and efficacious in improving Hb and iron levels in pediat.ic pat.ent. wit. IDA and act.ve IBD.

关键词： Iron deficiency anemia pediat.ic inflammat.ry bowel disease Int.avenous iron t.erapy Inflammat.ry bowel disease

Fjord-t.pe AIEgens Based on Inherent.t.rough-Space Conjugat.on

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CCS Chemist.y 2024年第7期6卷 1739-1747页

作者： Ye-Qiang Han Yuan Xie Jianyu Zhang Shiyu t.n Haoke Zhang Ben Zhong t.ng jonathan L.Sessler Feihe Huang St.ddart.Inst.t.t. of Molecular Science Department of ChemistryZhejiang UniversityHangzhou 310058 Zhejiang-Israel Joint.Laborat.ry of Self-Assembling Funct.onal Mat.rials ZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang UniversityHangzhou 311215 MOE key Laborat.ry of Macromolecular Synt.esis and Funct.onalizat.on Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310058 Cent.r for AIE Research College of Materials Science and EngineeringShenzhen UniversityShenzhen 518061 Depart.ent.of Chemist.y Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and ReconstructionThe Hong Kong University of Science and TechnologyKowloonHong Kong 999077 School of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen(CUHK-Shenzhen)Guangzhou 518172 Depart.ent.of Chemist.y The University of Texas at AustinAustinTexas 78712-1224 Green Cat.lysis Cent.r and College of Chemist.y Zhengzhou UniversityZhengzhou 450001

t.rough-space conjugat.on(t.C)is a noncovalent.y elect.onic int.ract.on t.at.is emerging as a pot.nt.al complement.t. t.rough-bond conjugat.on(t.C)-based st.at.gies for const.uct.ng luminescent.***,t.e design of efficient.luminogens based on t.C is current.y challenging due t. a lack of est.blished st.uct.re-propert. *** is part.cularly t.ue in t.e case of luminogens displaying aggregat.on-induced emission(AIE)*** t.is work,t.ree t.rphenyl derivat.ves were prepared,and t.eir phot.physical propert.es were syst.mically *** was found t.at.relat.ve t. t.e corresponding m-and p-linked analogues,t.e elect.onic int.ract.on of t.C is weakened while t.e st.engt. of t.C is commensurat.ly enhanced in t.e const.t.t.onal isomer cont.ining an o-linked fjordt.pe *** t.is set.of luminogens,t.e presence of a fjord-t.pe arrangement.promot.s a t.ansformat.on from aggregat.on-caused quenching t. *** invest.gat.ons involving congeneric quat.rphenyl and pent.henyl isomers support.t.e universalit. of t.e fjord-t.pe unit.as a framework for synt.esizing AIE-act.ve luminogens(AIEgens)wit. inherent.*** work not.only provides a novel set.of AIEgens but.also est.blishes t.e ut.lit. of t.C in cont.olling t.e phot.physical propert.es of nonconvent.onal and t.ist.d luminogens.

关键词： fjord-t.pe t.rough-space conjugat.on t.rough-bond conjugat.on aggregat.on-induced emission luminescence t.ist.d conformat.on