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Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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chinese Physics c 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.j. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya c. Adam Bourdarios L. Adamczyk S.V. Addepalli m.j. Addison j. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik m.N. Agaras j. Agarwala A. Aggarwal c. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot m. Ait Tamlihat B. Aitbenchikh I. Aizenberg m. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi j. Albert P. Albicocco G.L. Albouy S. Alderweireldt m. Aleksa I.N. Aleksandrov c. Alexa T. Alexopoulos F. Alfonsi m. Algren m. Alhroob B. Ali H.m.j. Ali S. Ali S.W. Alibocus m. Aliev G. Alimonti W. Alkakhi c. Allaire B.m.m. Allbrooke j.F. Allen c.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso c. Alpigiani m. Alvarez Estevez A. Alvarez Fernandez m. Alves cardoso m.G. Alviggi m. Aly Y. Amaral coutinho A. Ambler c. Amelung m. Amerl c.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev c. Anastopoulos T. Andeen j.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi c. Antel m.T. Anthony E. Antipov m. Antonelli F. Anulli m. Aoki T. Aoki j.A. Aparisi Pozo m.A. Aparo L. Aperio Bella c. Appelt A. Apyan N. Aranzabal S.j. Arbiol Val c. Arcangeletti A.T.H. Arce E. Arena j-F. Arguin S. Argyropoulos j.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah j. Assahsah K. Assamagan R. Astalos S. Atashi R.j. Atkin m. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia m. Bahmani A.j. Bailey V.R. Bailey j.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.m. Baldin P. Balek E. Ballabene F. Balli L.m. Baltes W.K. Balunas j. Balz E. Banas m. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak m. Barakat E.L. Barberio D. Barberis m. Barbero m.Z. Barel K.N. Barends T. Barillari m-S. Barisits T. Barklow P. Baron D.A. Baron mo The ATLAS collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron collider,as Standard model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS jET QUARK GLUON TAGGING

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抗PD-1免疫疗法与雄激素剥夺疗法联合可显著增强诱导转移性去势敏感前列腺癌的免疫浸润

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中国临床药理学杂志 2024年第1期40卷 51-51页

作者： HAWLEY j E OBRADOVIc A Z DALLOS m c 孟海峰

引自:HAWLEY j E,OBRADOVIc A Z,DALLOS m c,et ***-PD-1 immunotherapy with androgen depriva⁃tion therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer[j].cancer cell,2023,41(11):1972-1988.研究表明,与其他恶性肿瘤比较,原发性和去势抗性前列腺癌症(cRPc)的肿瘤微环境(TmE)缺乏免疫浸润。尽管雄激素剥夺疗法(ADT)可以在局部性前列腺癌中诱导复杂的免疫浸润,但在转移性去势敏感性前列腺癌(mcSPc)中TmE的组成、ADT或其它治疗方法在这方面的作用尚不明确。研究者对参与Ⅱ期临床试验(NcT03951831)患者的转移灶进行了全面的单细胞RNA测序(scRNA-seq)分析,该试验评估了标准化疗激素疗法联合抗PD-1免疫疗法的疗效。研究者基于蛋白质活性对TmE亚群进行了纵向分析,揭示了在多个转移灶中的免疫亚群。研究者还观察到这些免疫亚群对治疗反应的动态变化以及与临床结果具有相关性。本研究揭示了一种具有治疗耐药性、转录不同的肿瘤亚群,该亚群在治疗难治性患者中细胞数量增加。

关键词： Ⅱ期临床试验肿瘤微环境免疫疗法标准化疗前列腺癌临床结果激素疗法去势

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mind the “Gap”: A comparison of the Weekly Training Loads of English Premier League Academy Soccer Players in Under 23, Under 18 and Under 16 Age-Groups

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journal of Science in Sport and Exercise 2023年第1期5卷 34-43页

作者： jonathan m.Taylor jonathan L.madden Frances Hunter Ben j.Thorne Shaun j.mcLaren School of Health and Life Sciences Teesside UniversityMiddlesbroughUK Leeds United Football club LeedsUK middlesbrough Football club MiddlesbroughUK Hintsa Performance LondonUK Department of Sport and Exercise Sciences Durham UniversityDurhamUK

Purpose The transition into full-time training represents a key period in the development of young soccer *** we compared the weekly training loads(matches,field-,and resistance-training)of English Premier-League Academy soccer players from under-16(U16),under-18(U18)and under-23(U23)age-groups during a training *** Forty players(U16 n=13,U18 n=15 and U23 n=12)were monitored using global navigation satellite systems and differential ratings of perceived exertion(dRPE).External load metrics were total distance,high-speed running distance,[absolute:≥19.8 km/h,relative:≥87%of 30-15 final-velocity(vIFT)],sprint distance(absolute:≥25.2 km/h,relative:≥80%maximal sprint speed),and dynamic stress *** load metrics were dRPE training *** Other than relative sprint distance,overall weekly external training loads were substantially greater for U18s and U23s when compared with U16s[effect size range:1.09-1.99(moderate to large);±90%confidence limits~0.45].When compared with U16s,overall internal loads were substantially greater for U18s[0.69-0.95(moderate);±~0.40],but not *** in weekly training loads between U18s and U23s were *** Substantial differences in training loads between elite U16 players and their older counterparts,indicates the need for planned increases in training loads in anticipation of the transition into full-time training.

关键词： Team-sports RPE LTAD Individualised training Training load

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Pharmacological methods for ovarian function and fertility preservation in women with cancer:A literature review

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Oncology Research 2024年第8期32卷 1309-1322页

作者： ANA S.cVETANOVIc mATTEO LAmBERTINI KEVIN PUNIE GORANA G.mATOVINA BRKO NIKOLA D.ZIVKOVIc mAjA j.POPOVIc mARIjANA m.mILOVIc KOVAcEVIc LAZAR S.POPOVIc Department for Oncology Medical Faculty NisUniversity of NisNis18000Serbia clinic of Oncology University Clinical Centre NisNis18000Serbia Department of Internal medicine and medical Sciences(DimI) School of MedicineUniversity of GenovaGenova16100Italy Department of medical Oncology U.O.C Clinica di Oncologia MedicaIRCCS Ospedale Policlinico San MartinoGenova16100Italy Department of General medical Oncology and multidisciplinary Breast centre Leuven Cancer InstituteUniversity Hospitals LeuvenLeuven3001Belgium Department of medical Oncology Oncology Institute of VojvodinaSremska Kamenica21208Serbia Department for Pathology Medical Faculty NisUniversity of NisNis18000Serbia center for Pathology University Clinical Centre NisNis18000Serbia Faculty of medicine University of Novi SadNovi Sad21000Serbia Department of medical Oncology Institute of Oncology and Radiology SerbiaBelgrade11000Serbia

Oncofertility is an extremely signiﬁcant topic that is increasingly being discussed owing to increased evidence indicating that fertility preservation does not affect the treatment outcomes of patients with cancer but signiﬁcantly contributes to preserving life *** effect of chemotherapy can range from minimal effects to complete ovarian *** data are available on the effects of monoclonal antibodies and targeted therapies on the ovaries and *** ovarian suppression by administering a gonadotropin-releasing hormone agonist(GnRHa)during chemotherapy decreases the gonadotoxic effect of chemotherapy,thereby diminishing the chance of developing premature ovarian insufﬁciency(POI).At present,the concomitant administration of GnRH analogs during chemotherapy is the only accepted pharmacological method for preserving ovarian ***,most randomized studies on the effectiveness of luteinizing hormone-releasing hormone agonists during chemotherapy in preventing POI have been conducted in women with breast cancer,with a considerably small number of studies on patients with hematological ***,most randomized controlled trials on breast cancer have revealed a decrease in treatment-induced POI risk,regardless of the hormone receptor *** addition,studies on hematological malignancies have yielded negative results;nevertheless,theﬁndings must be interpreted with caution owing to numerous *** guidelines from the American Society of clinical Oncology and ESmO clinical Practice Guidelines recommend sperm,oocyte,and embryo cryopreservation as a standard practice and only offering GnRHa to patients when proven fertility preservation methods are not *** this manuscript,we present a comprehensive literature overview on the application of ovarian suppression with GnRHa during chemotherapy in patients with cancer by addressing preclinical and clinical data,as well as future perspectives in thisﬁeld

关键词： Gonadotropin-releasing hormone agonists(GnRHa) Fertility preservation Premature ovarian insufficiency(POI) Premenopausal patients

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Evaluation of the Antibacterial and Antifungal capacity of Nanoemulsions Loaded with Synthetic chalcone Derivatives Di-Benzyl cinnamaldehyde and Benzyl 4-Aminochalcone

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journal of Renewable materials 2024年第2期12卷 285-304页

作者： Flavia Oliveira monteiro da Silva Abreu Taysse Holanda joice Farias do Nascimento Henety Nascimento Pinheiro Rachel menezes castelo Hélcio Silva dos Santos Thais Benincá Patrícia da Silva malheiros júlio césar Sousa Prado Raquel de Oliveira Fontenelle maria madalena de camargo Forte Natural Polymers Laboratory PPGCNState University of CearáFortaleza60.714.903Brazil Polymeric materials Laboratory PPGE3MFederal University of Rio Grande do SulPorto Alegre91501-970Brazil Natural Product chemistry Laboratory PPGCNState University of CearáFortaleza60.714.903Brazil Food Hygiene and microbiology Laboratory PPGCTAFederal University of Rio Grande do SulPorto Alegre91501-970Brazil microbiology Laboratory Medicine SchoolFederal University of CearáSobral62010-560Brazil

With the increase in antimicrobial resistance,it has become necessary to explore alternative approaches for combating and preventing ***-cinnamaldehyde(cNm)and Benzyl4-amino(B4Am)are bioactive compounds derived from chalcones but with restricted solubility in aqueous *** can enhance the solubility of compounds and can be a promising alternative in the development of novel antimicrobials,with reduced side effects and prolonged *** objective of this study was to evaluate the stability of oil-in-water nanoemulsions loaded with two distinct types of chalcones at two different dosages,to propose a stable formulation with antimicrobial *** showed that nanoemulsions presented high encapsulation efficiency,low polydispersity index(PDI)and particle size below 200 nm,indicating that emulsification was a suitable method for nanoemulsion *** with higher dosages exhibited significant antimicrobial effects when compared to free chalcones and positive ***,B4Am nanoemulsions at higher dosages showed expressive activity against Salmonella minnesota,with a 420%greater inhibitory response compared to the free form and showing equivalence to the positive *** nanoemulsions showed excellent inhibitory activity at the highest dosage,equivalent to the positive control against *** and Staphylococcus *** greater number of conjugated bonds in cNm increased the antimicrobial activity in comparison with B4Am,and the formation of nanometric domains enhanced the bioavailability,being a promising alternative for antimicrobial applications.

关键词： Polysaccharide nanoemulsions S.aureus S.minnesota chalcones alginate

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Large magnetocaloric effect and magnetic properties of EuRhO3

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journal of Rare Earths 2024年第9期42卷 1724-1729页

作者： m.Lassri m.Sajieddine A.Elouafi A.El Hachmi S.El Ouahbi R.moubah Laboratory of Energy and materials Engineering (LGEm) University of Sultan Moulay SlimaneFaculty of Science and Technology (FST) Institute of Applied Physics (IAP)-School of Industrial management (EmINES) Mohammed Ⅵ Polytechnic University National School of Applied Sciences (ENSA) University of Sultan Moulay Slimane Laboratory of mechanics Production and Industrial Engineering (LMPGI)Higher School of Technology of Casablanca (ESTC)University of Hassan Ⅱ Casablanca Laboratory of Radiation on matter and Instrumentation (LRmI) Faculty of Science and Technology (FST) SettatHassan Ⅰ University Laboatory of Physics of Advanced materials and Thermic (LPmAT) Faculty of Science Ain Chock (FSAC)University of Hassan Ⅱ Casablanca

We report on the structural,magnetic,and magnetocaloric properties of *** oxidation states of Eu and Rh ions were studied using X-ray photoelectron spectroscopy（XPS）.It is found that the Eu ions are mainly in the divalent oxidation state while the Rh ions have+4 ***3powders are found to be antiferromagnetic with a second order magnetic transition at Neel temperature（TN=2.9 K）.Analysis of the magnetic susceptibility versus temperature data in terms of the curie=Weiss law:(χ=c/（T-θW）) for T>TN,yields θW=-3.1 K and effective magne tic moment ■,which is close to the theoretical value ■.The magnetic entropy change(-ΔSm),was determined by em ploying the thermodynam ic maxwell's *** μ0H=5 T and near TN,■ and relative cooling power（RcP） exhibit large values of 33.7 j/（kg·K） and 238 j/kg,*** large magnitude of-ΔSmand RcP show that the EuRhO3compound could be a potential candidate to be used in cryogenic magnetic refrigeration.

关键词： X-ray photoelectron spectroscopy cryogenic magnetic refrigeration magnetic properties magnetocaloric effect Rare earths

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Fully integrated and broadband Si-rich silicon nitride wavelength converter based on Bragg scattering intermodal four-wave mixing

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Photonics Research 2024年第3期12卷 I0001-I0010页

作者： VALERIO VITALI THALÍA DOmÍNGUEZ BUcIO HAO LIU jOSÉmANUEL LUQUE GONZÁLEZ FRANcIScO jURADO-ROmERO ALEjANDRO ORTEGA-mOÑUX GLENN cHURcHILL jAmES c.GATES jAmES HILLIER NIKOLAOS KALFAGIANNIS DANIELE mELATI jENS H.ScHmID ILARIA cRISTIANI PAVEL cHEBEN j.GONZALO WANGÜEmERT-PÉREZ ÑIGO mOLINA-FERNÁNDEZ FREDERIc GARDES cOSImO LAcAVA PERIKLIS PETROPOULOS Optoelectronics Research centre University of SouthamptonSouthampton SO171BJUK Electrical Computer and Biomedical Engineering DepartmentUniversity of PaviaPavia 27100Italy Telecommunication Research Institute(TELmA) Universidad de MálagaCEI Andalucı´a TECHE.T.S.I.Telecomunicación29010 MálagaSpain School of Science and Technology Nottingham Trent UniversityNottingham NG118NSUK Department of Electrical Engineering Eindhoven University of TechnologyEindhoven 5600 MBThe Netherlands Department of materials Science and Engineering University of IoanninaIoannina 45110Greece centre de Nanosciences et de Nanotechnologies UniversitéParis-SaclayCNRS91120 PalaiseauFrance Advanced Electronics and Photonics Research center National Research Council CanadaOttawaOntario K1A 0R6Canada

Intermodal four-wave mixing(FWm)processes have recently attracted significant interest for all-optical signal processing applications thanks to the possibility to control the propagation properties of waves exciting distinct spatial modes of the same *** allows,in principle,to place signals in different spectral regions and satisfy the phase matching condition over considerably larger bandwidths compared to intramodal ***,the demonstrations reported so far have shown a limited bandwidth and suffered from the lack of on-chip components designed for broadband manipulation of different *** demonstrate here a silicon-rich silicon nitride wavelength converter based on Bragg scattering intermodal FWm,which integrates mode conversion,multiplexing and de-multiplexing functionalities *** system enables wavelength conversion between pump waves and a signal located in different telecommunication bands(separated by 60 nm)with a 3 dB bandwidth exceeding 70 nm,which represents,to our knowledge,the widest bandwidth ever achieved in an intermodal FWm-based system.

关键词： scattering pump modal

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The challenging management of malignant ureteral obstruction:Analysis of a series of 188 cases

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current Urology 2024年第1期18卷 34-42页

作者： Alberto Artiles medina Inés Laso García Fernando González Tello Sara Álvarez Rodríguez manuel Hevia Palacios marina mata Alcaraz césar mínguez Ojeda Fernando Arias Funez Victoria Gómez Dos Santos Francisco javier Burgos Revilla Department of Urology Hospital Universitario Ramón y CajalMadridSpain Department of Radiology Hospital Universitario Ramón y CajalMadridSpain

Background:malignant ureteral obstruction(mUO)is a common condition that complicates the course of advanced *** aims of this study are to analyze the causes,management,and survival of patients with obstructive nephropathy due to malignant ureteric obstruction and to determine prognostic ***,we studied the complications and outcomes in patients who underwent urinary *** and methods:A retrospective study was conducted on patients with computed tomography-confirmed mUO between january 2016 and November ***,clinical,radiological,laboratory,and management data were *** curves were estimated using the Kaplan-meier method,and univariate and multivariate cox proportional hazards models were used to test the association between parameters and ***:A total of 188 patients were *** mean age was 69.01 years(SD,14.95 years),and the majority(54.8%)were *** most common mechanism leading to mUO was compression by a pelvic mass(36.9%),and the 3 most frequent tumors causing mUO were prostate(17.6%),bladder(16.5%),and rectal cancer(11.7%).Forty-seven patients(25%)underwent urinary diversion:23(48.9%)underwent double-j stenting and 21(44.7%)underwent percutaneous *** most common reason for urinary diversion was acute kidney injury(53.3%).Recovery of renal function was observed in 55.8%of the patients after urinary *** most frequently identified complications after urinary diversion were urinary tract infection(24.4%),hematuria(17.0%),and urinary sepsis(14.9%).The median survival after hydronephrosis diagnosis was 6.43 months(interquartile range,1.91-14.81 months).In patients who underwent urinary decompression,the median survival after urinary diversion was 8.67 months(interquartile range,2.99-17.28 months).In the multivariate analysis,a lower grade of hydronephrosis and cancer cachexia negatively impacted ***:cancer patients with mUO have a poor pro

关键词： Hydronephrosis Ureteral obstruction Neoplasms Urinary diversion Survival Prognosis

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Association between mental Disorders and Subsequent medical conditions

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四川生理科学杂志 2024年第4期46卷 217-217页

作者： Natalie c momen From the National center for Register-based Research (N.c.m. O.P.-R. E.A. M.K.C. S.D. J.-C.P.G.D. T.M.L. P.B.M. K.L.M. C.B.P. L.V.P. B.V. N.W. J.J.M.) Center for Integrated Register-based Research (E.A. P.B.M. C.B.P.) the Departments of Biomedicine-Human Genetics (A.D.B.) and Public Health (M.K.C. M.F.-G. K.M.I. M.V. A.P.) the Center for Integrative Sequencing (A.D.B.) and the Big Data Center for Environment and Health (C.B.P.) Aarhus University the Lundbeck Foundation Initiative for Integrative Psychiatric Research (E.A. A.D.B. S.D. O.M. P.B.M. K.L.M. M.N. C.B.P. L.V.P. A.J.S. B.V. T.W.) the Center for Genomics and Personalized Medicine (A.D.B.) the Department of Neurology (J.-C.P.G.D.) and the Research Unit Department of Psychosis (O.M.) Aarhus University Hospital and the Research Unit for General Practice (M.F.-G. A.R.R. M.V. A.P.) Aarhus the Copenhagen Research Center for Mental Health Mental Health Center Copenhagen Copenhagen University Hospital (M.E.B. M.N. H.J.S.) Psychiatric Center Copenhagen (L.V.K.) Faculty of Health and Medical Sciences (L.V.K.) the Department of Clinical Medicine (T.W.) and the Lundbeck Foundation GeoGenetics Center GLOBE Institute (T.W.) University of Copenhagen Copenhagen and the Institute of Biological Psychiatry Mental Health Center Sankt Hans Mental Health Services Capital Region Roskilde (A.J.S. T.W.) - all in Denmark the National Drug and Alcohol Research Centre University of New South Wales Sydney (L.D.) the Department of General Practice Melbourne Medical School University of Melbourne Melbourne VIC (J.M.G.) and the Queensland Brain Institute (C.C.W.L. S.S. J.J.M.) Queensland Centre for Mental Health Research the Park Centre for Mental Health (C.C.W.L. S.S. T.J.S. H.A.W. J.J.M.) and the School of Public Health Faculty of Medicine (H.A.W.) University of Queensland Brisbane - all in Australia the Departments of Psychology (P.J.) and Developmental Psychology (A.M.R.) Heymans Institute and the I

Background:Persons with mental disorders are at a higher risk than the general population for the subsequent development of certain medical ***:We used a population-based cohort from Danish national registries that included data on more than 5.9 million persons born in Denmark from 1900 through 2015 and followed them from 2000 through 2016,for a total of 83.9 million person-years.

关键词： conditions milli population

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The global stability and optimal control of the cOVID-19 epidemic model

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International journal of Biomathematics 2024年第1期17卷 1-28页

作者： Fengsheng chien Hassan Saberi Nik mohammad Shiraziant j.F.Gomez-Aguilar School of Finance and Accounting Fuzhou University of International Studies and Trade Fuzhou 352020 P.R.China Faculty of Business City university of Macao Macao 999078P.R.China Department of mathematics and Statistics University of Neyshabur NeyshaburIran cONAcyT-Tecnologico Nacional de mécico/cENIDET Interior Internado Palmira S/N Col.Palmira C.P.62490CuernavacaMorelosMérico

This paper considers stability analysis of a Susceptible-Exposed-Infected-Recovered-Virus(SEIRV)model with nonlinear incidence rates and indicates the severity and weakness of control factors for disease *** Lyapunov function using Volterra-Lyapunov matrices makes it possible to study the global stability of the endemic equilibrium *** optimal control strategy is proposed to prevent the spread of coronavirus,in addition to governmental *** objective is to minimize together with the quantity of infected and exposed individuals while minimizing the total costs of treatment.A numerical study of the model is also carried out to investigate the analytical results.

关键词： Global stability SEIRV epidemic model dynamical systems Volterra-Lyapunov stability optimal control

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