检索结果-南通市图书馆

Acute Type A Aortic Dissection—Replacement of Ascending Aorta, Aortic Arch and Antegrade Stenting of the Descending Thoracic Aorta Using the Thoraflex™Hybrid Plexus Device (Terumo Aortic)—“Frozen Elephant Trunk”: The Plymouth Way!

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Thoracic Surgery 2020年第3期10卷 69-79页

作者： Marios Patronis jonathan Unsworth-white James Kuo Department of Cardiothoracic Surgery Division of Cardiac Surgery Derriford Hospital Devon UK

Objectives: To describe our technique for the implantation of the Thoraflex Hybrid prosthesis for replacement of the aortic arch in a safe and reproducible way. Materials: Thoraflex™ Hybrid Plexus Device (Terumo Aortic). Design: Drawing on our own experience over the past 4 years in the management of acute type A aortic dissection, we have distilled the essentials of our “Frozen Elephant Trunk” technique which have led us through our own learning curve to the improved management of this taxing condition. Method/ Results: Small extension of the median sternotomy incision along the medial border of sternocleidomastoid muscle. End to side graft anastomosis near the origin of the left subclavian artery during cooling on bypass towards 20 degrees. Attention to cardiac protection and maintenance of cerebral perfusion during the shortened corporeal arrest period. Excellent results in 24 consecutive AAAD patients with just one hospital mortality. Conclusions: We believe we are entering a new phase in the treatment of AAAD, facilitated by the availability of a hybrid prosthesis which combines expanding stent technology with familiar surgical graft material. Our particular management of the left subclavian artery and of the cerebral circulation during implantation has contributed to an expeditious and reproducible method of treating dissection within the arch of the aorta and beyond.

关键词： Aortic Dissection Total Arch Replacement Stenting of the Descending Thoracic Aorta Frozen Elephant Trunk

Structure of the Ligated Ag60 Nanoparticle [{Cl@Ag12}@Ag48（dppm）12]（where dppm=bis（diphenylphosphino）methane）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Physics 2019年第2期32卷 182-186,I0002页

作者： Athanasios Zavras Antonija Mravak Margarita Buzancic jonathan M.white Vlasta Bonacic-Koutecky Richard A.J.O’Hair School of Chemistry and Bio21 Molecular Science and Biotechnology Institute University of Mel- bourne 30 Flemington Rd Parkville Victoria 3010 Australia Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM) at Interdisciplinary Center for Advanced Sciences and Technology (ICAST) University of Split Poljicka cesta 35 Split 21000 Croatia Chemistry Department Humboldt University of Berlin Brook-Taylor-Strasse 2 Berlin 12489 Germany

A novel bisphosphine ligated Ag60 nanocluster,[{Cl@Ag12}@Ag48(dppm)12], has been dis-covered and characterized by X-ray crystallography. It consists of a central chloride located inside an icosahedral silver core layer, which is further encased by a second shell of 48 silver atoms/ions, which are capped with 12 bis(diphenylphosphino)methane (dppm) ligands. Due to lack of sufficient material the cluster could not be further characterized by other methods. DFT calculations were carried out on the cation [{Cl@Ag12}@Ag48(dppm)12]+ to determine if it corresponds to a superatom with a core count of n=58. The DFT optimized structure is in agreement with X-ray ndings, but the low value of the HOMO-LUMO gap does not support superatom stability.

关键词： Nanoparticle DFT calculations X-ray crystallography

Complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar El Baba Ali Tfaily Firas Kobeissy Juanmarco Gutierrez Gonzalez Daniel Refai Gerald R.Rodts Christian Mustroph David Gimbel jonathan Grossberg Daniel L.Barrow Matthew F.Gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA Center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

Clinical utilities and biological characteristics of melanoma sentinel lymph nodes

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2016年第2期7卷 174-188页

作者： Dale Han Daniel C Thomas jonathan S Zager Barbara Pockaj Richard L white Stanley PL Leong Department of Surgery Yale University School of Medicine Department of Cutaneous Oncology Moffitt Cancer Center Mayo Clinic Division of Surgical Oncology Carolinas Medical CenterLevine Cancer Institute Center for Melanoma Research and Treatment California Pacific Medical Center

An estimated 73870 people will be diagnosed with melanoma in the United States in 2015,resulting in 9940 *** majority of patients with cutaneous melanomas are cured with wide local ***,current evidence supports the use of sentinel lymph node biopsy(SLNB) given the 15%-20% of patients who harbor regional node *** importantly,the presence or absence of nodal micrometastases has been found to be the most important prognostic factor in earlystage melanoma,particularly in intermediate thickness *** review examines the development of SLNB for melanoma as a means to determine a patient's nodal status,the efficacy of SLNB in patients with melanoma,and the biology of melanoma metastatic to sentinel lymph *** randomized trials have guided the development of practice guidelines for use of SLNB for melanoma and have shown the prognostic value of *** the rapidly advancing molecular and surgical technologies,the technical aspects of diagnosis,identification,and management of regional lymph nodes in melanoma continues to evolve and to ***,there is ongoing research examining both the role of SLNB for specific clinical scenarios and the ways to identify patients who may benefit from completion lymphadenectomy for a positive *** further data provides sufficient evidence to alter national consensusbased guidelines,SLNB with completion lymphadenectomy remains the standard of care for clinically node-negative patients found to have a positive SLN.

关键词： Melanoma Metastasis Review Biologic characteristics Sentinel lymph node Sentinel lymph node biopsy

Hydrogen peroxide ingestion with injury to upper gastrointestinal tract

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2017年第10期5卷 378-380页

作者： jonathan V Martin Choichi Sugawa Michael and Marian Ilitch Department of Surgery 6-C University Health Center

Hydrogen peroxide is a common over-the-counter solution that has developed a growing body of literature regarding toxic ingestion. Intentional ingestion of high concentration hydrogen peroxide for health purposes has gained popularity in certain patient populations; purported benefits are due to the increased oxygen released into the blood stream. We present for evaluation one such case with associated imaging that presented to our urban medical center. A brief review of the literature was also performed noting current recommendations regarding both outcomes and indications for endoscopy as well as hyperbaric oxygen therapy following ingestion of hydrogen peroxide. Our patient was a 51-year-old white female who presented with foamy hematemesis after ingesting 10 drops of 35% hydrogen peroxide as part of a home remedy to cleanse her colon and improve blood oxygenation. In addition to hematemesis,she also reported diffuse abdominal pain with sore throat and hoarse voice. Her imaging demonstrated portal venous gas and gastric edema. She was admitted for hyperbaric oxygen therapy and underwent upper endoscopy demonstrating diffuse esophagitis and gastritis with white exudate and multiple petechiae. She was later discharged home in stable condition and was lost to follow-up.

关键词： Hydrogen peroxide Caustic injury Hyperbaric oxygen therapy Ingestion of hydrogen peroxide Arterial gas emboli

CREATING LIVABLE INFRASTRUCTURE:THE CONNECTOAKLAND VISION TO RECONNECT NEIGHBORHOODS AND CONNECT CITIES THROUGH FREEWAY REMOVAL

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Green Building 2016年第2期11卷 1-21页

作者： Andrew Faulkner jonathan Fearn Chris Sensenig Brian Stokle LEED Green Associate at Van Meter Williams Pollack Development at SummerHill Housing Group *** Urban Designer-Associate at Van Meter Williams Pollack San Francisco Recreation and Parks

Throughout the second half of the 20th Century,our nation’s cities were marred by the onslaught of unsustainable suburbanization and the expansion of limited access highways that ripped through urban centers and divided communities within *** with systematic disinvestment from redlining and white flight,these forces combined to create lasting physical,social and economic hardships in cities across the *** the last 20 years,cities have rebounded in America and new patterns of thought focused on livability,walkability and urban form have started to sprout:from the Big-Dig in Boston to Octavia Boulevard and the Embarcadero in San Francisco,cities are reassessing the value of highways that solely move automobiles through cities,and have started to focus on how these pieces of infrastructure impact the daily lives and economic interests of a their residents and *** Oakland,California,through the efforts of ConnectOAKLAND,the city is taking up the mantle of this new pattern of thought and is beginning the planning process to reconnect West Oakland to Downtown by transforming an underutilized freeway(I-980)into a multi-modal transportation corridor that reestablishes the historic urban *** project’s dual benefit will reconnect two of Oakland’s historic neighborhoods while better connecting Oakland along with the entire East Bay to San Francisco,San Jose and Silicon Valley through the incorporation of a second transbay tunnel for Bay Area Rapid Transit(BART),commuter rail(Caltrain),and high speed rail(HSR).This article will explore the ConnectOAKLAND vision for I-980 as a case study for current and future patterns of highway removal,and as a part of the national movement to rethink the role of urban highways and holistically re-envision the US transportation infrastructure.

关键词： livable infrastructure freeway removal transit oriented development

Left Atrial Appendage Occlusion Device: Evaluation of Surgical Implant Success and <i>in Vivo</i>Corrosion Performance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Science 2012年第1期3卷 28-33页

作者： jonathan Snyder Amy M. Engel Kevin C. white Noah Budiansky J. Michael Smith Department of Surgery Good Samaritan Hospital Cincinnati USA E. Kenneth Hatton MD Institute for Research and Education Cincinnati USA Exponent Inc. Natick Massachusetts USA

Objective: The purpose of this study was to compare the in vivo corrosion resistance of the implanted titanium, nitinol annular occlusion device to a control device, i.e. an implantable device containing nitinol, approved by the FDA and currently on the market. Methods: The annular occlusion device is a self-closing, implantable clip. Three canines underwent placement of devices on the left and right atrial appendages. Two Vnus U-clips were secured to either atrium. On post-operative day 95, animals underwent en-bloc cardiac resection via the previous left thoracotomy incision. The annular occlusion device and U-clips were dissected free from the atria. The polyester fabric and tissue ingrowth were removed from the devices and were sent for corrosion analysis. Results: Gross examination of resected hearts of two canines revealed no abnormalities. The compressed endocardial surfaces were completely fused and the appendages fully necrosed. All devices were located and harvested. The annular occlusion device clips and Medtronic Vnus U-clips were evaluated using scanning electron microscopy. Both low and high magnification examination of the nitinol springs and the site of insertion of the nitinol springs into the titanium tubes in the annular occlusion device showed no evidence of localized corrosion. In no case was any evidence of general or localized corrosion found in the form of metallic oxidation. Conclusion: The annular occlusion device provides safe and reliable exclusion of the left atrial ap-pendage without evidence of general or localized corrosion over the 95-day exposure period in canines and may therefore provide a reasonable therapeutic option for stroke risk reduction in patients with atrial fibrillation.

关键词： Atrial Appendage Occlusion Device Atrial Fibrillation Exclusion of Left Atrial Appendage

Local Adaptive Gradient Variance Attack for Deep Fake Fingerprint Detection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第1期78卷 899-914页

作者： Chengsheng Yuan Baojie Cui Zhili Zhou Xinting Li Qingming jonathan Wu Engineering Research Center of Digital Forensics Ministry of EducationNanjing University of Information Science and TechnologyNanjing210044China School of Computer Science Nanjing University of Information Science and TechnologyNanjing210044China Institute of Artificial Intelligence and Blockchain Guangzhou UniversityGuangzhou510006China School of International Relations National University of Defense TechnologyNanjing210039China Department of Electrical and Computer Engineering University of WindsorWindsorN9B 3P4Canada

In recent years,deep learning has been the mainstream technology for fingerprint liveness detection(FLD)tasks because of its remarkable ***,recent studies have shown that these deep fake fingerprint detection(DFFD)models are not resistant to attacks by adversarial examples,which are generated by the introduction of subtle perturbations in the fingerprint image,allowing the model to make fake *** of the existing adversarial example generation methods are based on gradient optimization,which is easy to fall into local optimal,resulting in poor transferability of adversarial *** addition,the perturbation added to the blank area of the fingerprint image is easily perceived by the human eye,leading to poor visual *** response to the above challenges,this paper proposes a novel adversarial attack method based on local adaptive gradient variance for *** ridge texture area within the fingerprint image has been identified and designated as the region for perturbation ***,the images are fed into the targeted white-box model,and the gradient direction is optimized to compute gradient ***,an adaptive parameter search method is proposed using stochastic gradient ascent to explore the parameter values during adversarial example generation,aiming to maximize adversarial attack *** results on two publicly available fingerprint datasets show that ourmethod achieves higher attack transferability and robustness than existing methods,and the perturbation is harder to perceive.

关键词： FLD adversarial attacks adversarial examples gradient optimization transferability

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

潮汐