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Statistical Theory and Related Fields 2019年第2期3卷 178-185页

作者： Junni l.Zhang john Bryant Guanghua School of Management Center for Statistical Science and Center for Data SciencePeking UniversityBeijingPeople’s Republic of China Bayesian Demography limited ChristchurchNew Zealand

Demographic estimation becomes a problem of small area estimation when detaileddisaggregation leads to small cell *** usual difficulties of small area estimation are compounded when the available data sources contain measurement *** present a Bayesianapproach to the problem of small area estimation with imperfect data *** overall modelcontains separate submodels for underlying demographic processes and for measurement *** unknown quantities in the model,including coverage ratios and demographic rates,are estimated jointly via Markov chain Monte Carlo *** approach is illustrated usingthe example of provincial fertility rates in Cambodia.

关键词： Measurement error Bayesian hierarchical model coverage errors fertility Cambodia small area estimation

Comparative Study of Faculty Evaluation of Teaching Practice between Chinese and *** of Higher Education

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Frontiers of Education in China 2011年第2期6卷 200-226页

作者： Qianyi CHEN john l.YEAGER Office of Admissions and Financial Aid University of PittsburghPittsburghPA 15260USA School of Education University of PittsburghPittsburghPA 15260USA

Along with the“massification”of higher education in China since the late 1990s,the issue of quality and excellence appeared at the top of China's higher education *** faculty evaluation of teaching is one of the major approaches adopted by China's higher education sector to pursue quality and excellence,it is valuable to examine the effectiveness of faculty evaluation of teaching practices adopted by the Chinese higher education institutions(HEIs).Study of current literature reveals some similarities and differences between the faculty evaluation of teaching policies and practices between Chinese and American higher education *** paper examines the specific practices adopted by some top-tier Chinese HEIs and American elite colleges and universities,summarizes and analyzes the major differences and similarities of faculty evaluation of teaching practices between these two countries'top-tier HEIs,and discusses the applicability of the American models to the Chinese setting of higher ***,a set of best practices regarding faculty evaluation of teaching are proposed for Chinese HEIs.

关键词： faculty evaluateon of teaching Project 985 universities student ratings peer evaluation self-evaluation

Rapid accessibility evaluation for ballistic lunar capture via manifolds: A Gaussian process regression application

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Astrodynamics 2022年第4期6卷 375-397页

作者： Sandeep K.Singh john l.Junkins Manoranjan Majji Ehsan Taheri Department of Aerospace Engineering Texas A&M UniversityCollege StationTX 77843USA Department of Aerospace Engineering Auburn UniversityAuburnAL 36849USA

In this study,a supervised machine learning approach called Gaussian process regression(GPR)was applied to approximate optimal bi-impulse rendezvous maneuvers in the cis-lunar *** demonstrate the use of the GPR approximation of the optimal bi-impulse transfer to patch points associated with various invariant manifolds in the cis-lunar *** proposed method advances preliminary mission design operations by avoiding the computational costs associated with repeated solutions of the optimal bi-impulsive lambert transfer because the learned map is computationally *** approach promises to be useful for aiding in preliminary mission *** use of invariant manifolds as part of the transfer trajectory design offers unique features for reducing propellant consumption while facilitating the solution of trajectory optimization *** ballistic capture coasts are also very attractive for mission guidance,navigation,and control robustness.A multi-input single-output GPR model is presented to represent the fuel costs(in terms of theΔV magnitude)associated with the class of orbital transfers of interest *** developed model is also proven to provide efficient *** multi-resolution use of local GPRs over smaller sub-domains and their use for constructing a global GPR model are also *** of the unique features of GPRs is that they provide an estimate of the quality of approximations in the form of covariance,which is proven to provide statistical consistency with the optimal trajectories generated through the approximation *** numerical results demonstrate our basis for optimism for the utility of the proposed method.

关键词： Gaussian process regression supervised learning invariant manifolds ballistic transfers Bayesian inference

Tissue engineering for neuromuscular disorders of the gastrointestinal tract

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World Journal of Gastroenterology 2012年第47期18卷 6918-6925页

作者： Kenneth l Koch Khalil N Bitar john E Fortunato Khalil N Bitar Section on Gastroenterol-ogy Department of Medicine Wake Forest University School ofMedicine Winston-Salem NC 27101 United States Wake Forest Institute for Regenerative Medicine Wake Forest School of Medicine Winston-Salem NC 27101United States

The digestive tract is designed for the optimal processing of food that nourishes all organ *** esophagus,stomach,small bowel,and colon are sophisticated neuromuscular tubes with specialized sphincters that transport ingested food-stuffs from one region to *** contractions move ingested solids and liquids from the esophagus into the stomach;the stomach mixes the ingested nutrients into chyme and empties chyme from the stomach into the *** to-and-fro movement of the small bowel maximizes absorption of fat,protein,and *** contractions are necessary for colon function and defecation.

关键词： Neuromuscular disorders Gastrointestinal tract Dysfunction Esophagus Stomach Small bowel Colon

Intermittent suckling with or without comingling of non-littermate piglets before weaning improves piglet performance in the immediate post-weaning period when compared with conventional weaning

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Journal of Animal Science and Biotechnology 2017年第3期8卷 721-732页

作者： Diana l.Turpin Pieter langendijk Kate Plush john R.Pluske School of Veterinary and life Sciences Murdoch UniversityMurdochWA 6150Australia Trouw Nutrition Veerstraat 38Boxmeer 5831 iNThe Netherlands South Australian Research and Development Institute Roseworthy CampusJS Davis BuildingRoseworthySA 5371Australia Present address:SunPork Farms 563 Coleman RoadPinkerton PlainsSA 5400Australia

Background： In this experiment, intermittent suckling（IS） with or without the co-mingling（Co M） of piglets was studied as a method to stimulate solid feed intake and reduce post-weaning ***： Three weaning regimes using 30 multiparous sows were compared：（1） conventional weaning（CW）（n = 10 litters）, where piglets had continuous access to the sow until weaning（d 0, farrowing = d-25 relative to weaning）;（2） intermittent suckling（IS）（n = 10 litters）, where piglets were separated from the sow for 8 h/d starting at d-7（relative to weaning）; and（3） intermittent suckling with co-mingling（ISCo）（n = 10 litters） where IS started at d-7 and two litters were housed together during separation and then returned to their original sow. Ad libitum creep feed was available from d-17. At weaning pigs were housed in pens of 11 pigs, 27 pens in total. The ISCo treatment was divided in half to examine effects of different mixing strategies after weaning. Half of the ISCo litters were kept in familiar groups（ISCo F, familiar, n = 4） and the other half were mixed within treatment resulting in groups of unfamiliar pigs（ISCo NF, not familiar, n = 5）, the same as IS（n = 9） and CW（n = 9） ***： The ISCo piglets ate more creep feed in the week before weaning（P 〈 0.01）, but also showed more aggressive and manipulative behaviour on first day of Co M compared with CW piglets（P 〈 0.05）. IS with or without Co M increased exploratory and play behaviour on the first day of treatment intervention（P 〈 0.001） and increased sleeping behaviour on the last day of treatment intervention compared with CW（P 〈 0.001）. Mixing strategy at weaning had an effect on performance data with the highest growth and feed intake seen in ISCo F pigs 2 to 8 d after weaning（P 〈0.001）. IS and ISCo NF pigs also grew faster and ate more than CW pigs 2 to 8 d after weaning（P 〈 0.001）. Post-weaning injury scores suggested reduced aggression in ISCo as evidenced by reduced redness（skin irritation）（P 〈 0.05）, a

关键词： Behaviour Co-mingling Intermittent suckling Piglet Weaning

Effect of music on patients undergoing outpatient colonoscopy

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World Journal of Gastroenterology 2006年第45期12卷 7309-7312页

作者： Matthew l Bechtold Rodney A Perez Srinivas R Puli john B Marshall Division of Gastroenterology University of Missouri School of Medicine Columbia Missouri United States

AIM: To evaluate the effect of relaxing music during colonoscopy under low-dose conscious sedation, on patient satisfaction, scope insertion time and procedure duration, medication doses, and the perceived adequacy of sedation and scope insertion difficulty on the part of the endoscopist. METHODS: One hundred and sixty-seven consecutive adult outpatients presenting for routine colonoscopy under low-dose conscious sedation were randomized to undergo their procedures either with music played during the procedure or no music played. RESUlTS: There were no statistical differences between the two groups in terms of meperidine dose, midazolam dose, time to reach the cecum, total procedure time, endoscopist assessment of scope insertion difficulty, endoscopist assessment of adequacy of sedation, or the pain experience of the patients during their procedure. The music group did report significantly better overall procedure satisfaction as compared to the non music group on two of our three different scales. CONClUSION: While music does not result in shortened procedure times, lower doses of sedative medications or perceived patient pain, the patients who have music playing during their procedures report modestly greater satisfaction with their procedures.

关键词： Colonoscopy Gastrointestinal endoscopy Music Music therapy Relaxation music

Bile acid receptors and signaling crosstalk in the liver, gut and brain

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liver Research 2021年第3期5卷 105-118页

作者： Jessica M.Ferrell john Y.l.Chiang Integrative Medical Sciences Northeast Ohio Medical UniversityRootstownOHUSA

Bile acids are physiological detergents derived from cholesterol that aid in digestion and nutrient ab-sorption,and they play roles in glucose,lipid,and energy metabolism and in gut microbiome and metabolic *** acids mediate crosstalk between the liver and gut through bactericidal modulation of the gut microbiome,while gut microbes influence the composition of the circulating bile acid *** research indicates bile acids may also be important mediators of neurological disease by acting as peripheral signaling molecules that activate bile acid receptors in the blood-brain barrier and in the brain *** review highlights the role of bile acids in maintaining liver and gut microbe homeostasis,as well as their function as mediators of cellular signaling in the liver-gut-brain axis.

关键词： Bile acid metabolism Farnesoid X receptor(FXR) Gut-brain axis Microbiome Neurodegenerative disease Takeda G protein-coupled receptor(TGR5)

Growth, Development and Yield of Kenaf as Affected by Planting Dates and N Fertilization

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Open Journal of Applied Sciences 2024年第3期14卷 707-720页

作者： Julius Yirzagla Peter Quandahor Iddrisu Yahaya Olivia Aguriboba Akanbelum listowell Aditwin Akologo john Bokaligidi lambon Abdul-Wahab M. Imoro Kwadwo Gyasi Santo CSIR-SARI Nyankpala Ghana St Vincent College of Education Yendi Ghana Gbewaah College of Education Pusiga-Bawku Ghana CSIR-Head Office Accra Ghana C.K. Tedam University of Technology and Applied Sciences Navrongo Ghana University of Energy and Natural Resources Sunyani Ghana

Kenaf (Hibiscus cannabinus l) consists of various beneficial components like stalks, seeds, leaves, fibers, oils, proteins, allelopathic chemicals, and fiber strands, among other things. Despite the numerous uses of the crop, there is little or no information on optimum agronomic practices such as planting date and N fertilization of the crop in the Upper East Region (UER) of Ghana where the crop is widely cultivated by smallholder farmers. Field experiments were therefore carried out in 2020 and repeated during the 2021 cropping season in the study area. The objective of the study was to determine appropriate planting date and N fertilization for increased kenaf productivity. In each year, the treatments consisted of 3 × 5 factorial combinations of three planting dates (1st July, 7th July and 14th July) and five levels of N (0, 20, 40, 60 and 80 kg/ha) replicated three times. The design of the experiment was a split-plot with the N fertilizer as the main plot and the planting date assigned to sub plot. The results showed that, planting kenaf in early (1st) July or N fertilization at the rate of 60 kg/ha increased plant density, stem height, stem diameter, dry bast and core yields in both cropping seasons.

关键词： Growth Fibres Bast Yield Core Yield

Prostaglandin E1 administration post liver transplantation and renal outcomes:A retrospective single center experience

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World Journal of Transplantation 2024年第4期14卷 101-109页

作者： Vinay Jahagirdar Mohamed Ahmed Ifrah Fatima Hassam Ali laura Alba john H Helzberg lee S Cummings Matthew Wilkinson Jameson Forster Alisa likhitsup Department of Internal Medicine Saint Luke’s Health System of Kansas City and the University of Missouri-Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Internal Medicine Department of Gastroenterology and HepatologySaint Luke’s Health System of Kansas City and University of Missouri-Kansas CityKansas CityMO 64111United States Department of Surgery University of Missouri-Kansas City and Transplant SurgerySaint Luke’s Hospital of Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BACKGROUND Prostaglandin E1(PGE1),or alprostadil,is a potent vasodilator that improves hepatic blood flow and reduces ischemia-reperfusion injury post-liver transplantation(lT).However,the benefits of PGE1 on renal function after lT have not yet been well *** To assess the impact of PGE1 administration on renal function in patients who underwent liver or liver-kidney *** This retrospective study included all patients who underwent liver or liverkidney transplant at our institution from January,2011 to December,*** were classified based on whether they received ***1 was administered post-lT to those with transaminases>1000 U/l in the immediate postoperative ***,post-lT treatments and/or complications,renal function,and survival were *** logistic regression analysis was performed,and a two-tailed P valuelly *** A total of 145 patients underwent lT,with 44(30%)receiving *** patient characteristics were comparable,except the PGE1 group had significantly higher aspartate aminotransferase(AST)(1961.9 U/l±1862.3 U/l vs 878 U/l±741.4 U/l,P=0.000),alanine aminotransferase(1070.6 U/l±895 U/l vs 547.7 U/l±410 U/l,P=0.000),international normalized ratio on post-lT day 1(2±0.74 vs 1.8±0.4,P=0.03),a longer intensive care unit stay(8.1 days±11.8 days vs 3.8 days±4.6 days,P=0.003),more vasopressor use(55.53 hours±111 hours vs 16.33 hours±26.3 hours,P=0.002),and higher immediate postoperative complications(18.6%vs 4.9%,P=0.04).The PGE1 group also had a significantly higher 90-day readmission rate(29.6%vs 13.1%,P=0.02)and lower 1-year liver graft survival(87.5%vs 98.9%,P=0.005).However,30-day readmission(31.6%vs 27.4%,P=0.64),lT complications(hepatic artery thrombosis,biliary complications,rejection of liver graft,cardiomyopathy),1-year patient survival(96.9%vs 97.8%,P=0.77),overall liver graft survival,and overall patient survival were similar between t

关键词： liver transplantation Alprostadil Protective agents Transplant Prostaglandin E1

Treatment with analgesics after mouse sciatic nerve injury does not alter expression of wound healingassociated genes

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Neural Regeneration Research 2016年第1期11卷 144-149页

作者： Matt C.Danzi Dario Motti Donna l.Avison john l.Bixby Vance P.lemmon The Miami Project to Cure Paralysis University of MiamiLois Pope LIFE Center Department of Surgery Leonard M. Miller School of Medicine University of Miami Department of Neurological Surgery University of Miami Department of Molecular and Cellular Pharmacology University of Miami

Animal models of sciatic nerve injury are commonly used to study neuropathic pain as well as axon regeneration. Administration of post-surgical analgesics is an important consideration for animal welfare, but the actions of the analgesic must not interfere with the scientific goals of the experiment. In this study, we show that treatment with either buprenorphine or acetaminophen following a bilateral sciatic nerve crush surgery does not alter the expression in dorsal root ganglion（DRG） sensory neurons of a panel of genes associated with wound healing. These findings indicate that the post-operative use of buprenorphine or acetaminophen at doses commonly suggested by Institutional Animal Care and Use Committees does not change the intrinsic gene expression response of DRG neurons to a sciatic nerve crush injury, for many wound healing-associated genes. Therefore, administration of post-operative analgesics may not confound the results of transcriptomic studies employing this injury model.

关键词： acetaminophen analgesics axon buprenorphine dorsal root ganglia gene expression peripheral nerve injuries regeneration sciatic nerve wound healing