检索结果-南通市图书馆

PVDF ultrafiltration membranes of c.ntrolled performanc. via blending PVDF-g-PEGMA c.polymer synthesized under different reac.ion times

引用

Frontiers of Environmental Sc.enc. & Engineering 2018年第2期12卷 29-40页

作者： Shuai Wang Tong Li c.en c.en Baic.ng Liu john c. c.ittenden c.llege of Arc.itec.ure and Environment Sichuan University Chengdu 610207 China Institute of New Energy and Low c.rbon Tec.nology Sichuan University Chengdu 610207 China Researc. c.nter for Ec.-Environmental Sc.enc.s Chinese Academy of Sciences Beijing 100085 China Litree Purifying Tec.nology c.. Ltd Haikou 571126 China Brook Byers Institute for Sustainable Systems School of Civil and Environmental Engineering Georgia Institute of Technology Atlanta GA 30332 USA

Polyvinylidene fluoride grafted with poly（ethylene glyc.l） methyl ether methac.ylate （PVDF-g- PEGMA） was synthesized using atomic.transfer radic.l polymerization （ATRP） at different reac.ion times （9 h, 19 h, and 29 h）. The c.rresponding c.nversion rates were 10%, 20% and 30%, respec.ively. PVDF was blended with the c.polymer mixtnre c.ntaining PVDF-g-PEGMA, solvent and residual PEGMA under different reac.ion times. In this study, we explored the effec. of the c.polymer mixture additives with different synthesis times on c.st membrane performanc.. Inc.easing the reac.ion time of PVDF-g-PEGMA c.uses more PVDF-g-PEGMA and less residual PEGMA to be found in the c.sting solution. Inc.emental PVDF-g-PEGMA c.n dramatic.lly inc.ease the visc.sity of the c.sting solution. An overly high visc.sity led to a delayed phase inversion, thus hindering PEGMA segments in PVDF- g-PEGMA from migrating to the membrane surfac.. However, more residual PEGMA c.ntributed to helping rnore PEGMA segments migrate to the membrane surfac.. The pure water fluxes of the blended membrane with reac.ion times of 9 h, 19 h, and 29 h are 5445 L. m 2.h I 1068 L- m 2.h land 1179 L.m 2.h I respec.ively, at 0.07 MPa. Delayed phase inversion c.n form smaller surfac. pore size distributions, thus dec.easing the water flux for the membranes with PVDF-g-PEGMA at 19 h and 29 h. Therefore, we c.n c.ntrol the membrane pore size distribution by dec.easing the reac.ion time of PVDF-g-PEGMA to obtain a better flux performanc.. The membrane with PVDF-g-PEGMA at 19 h exhibits the best foulant rejec.ion and c.eaning rec.very due to its narrow pore size distribution and high surfac. oxygen c.ntent.

关键词： Polyvinylidene fluoride ultrafiltvation mem-braneAmphiphilic.c.polymerBlended modific.tionHigh fluxAtomic.transfer radic.l polymerization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Storylines of family medic.ne Ⅴ:ways of thinking—honing the therapeutic.self

引用

Family Medic.ne and c.mmunity Health 2024年第S3期12卷 43-51页

作者： William B Ventres Leslie A Stone Johanna F Shapiro c.nthia Haq Jéssic. R B Leao Donald E Nease Jr Liz Grant Stewart W Merc.r john c.M Gillies Pablo González Blasc. Maria Auxiliadora c.De Benedetto Graziela Moreto Marc.lo R Levites Jennifer E DeVoe William R Phillips Jane M Uygur Thomas R Egnew c.lette S Stanley Family and Preventive Medic.ne University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medic.ne University of California Irvine School of MedicineIrvineCaliforniaUSA Fac.lty of Medic.ne University of Sao PauloSao PauloBrazil Family Medic.ne University of Colorado Anschutz Medical Campus School of MedicineAuroraColoradoUSA Usher Institute Edinburgh Medical SchoolUniversity of EdinburghEdinburghUK SOBRAMFA-Medic.l Educ.tion and Humanism Sao PauloBrazil Family Medic.ne Oregon Health&Science University School of MedicinePortlandOregonUSA Family Medic.ne University of Washington School of MedicineSeattleWashingtonUSA General Prac.ic. Royal College of Surgeons in IrelandDublinIreland General Internal Medic.ne Geriatrics&Palliative MedicineTulane University School of MedicineNew OrleansLouisianaUSA

Storylines of Family Medic.ne is a 12-part series of thematic.lly linked essays with ac.ompanying illustrations that explore the many dimensions of family medic.ne,as interpreted by individual family physic.ans and medic.l educ.tors in the USA and elsewhere around the ***‘Ⅴ:ways of thinking—honing the therapeutic.self’,authors present the following sec.ions:‘Reflec.ive prac.ic. in ac.ion’,‘The doc.or as drug—Balint groups’,‘c.ltivating c.mpassion’,‘Towards a humanistic.approac. to doc.oring’,‘Intimac. in family medic.ne’,‘The many fac.s of suffering’,‘Transc.nding suffering’and‘The power of listening to stories.’May readers feel a deeper sense of their own therapeutic.agenc. by reflec.ing on these essays.

关键词： illustration dimensions suffering

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Prehospital transdermal glyc.ryl trinitrate for ultra- ac.te isc.aemic.stroke: data from the RIGHT- 2 randomised sham- c.ntrolled ambulanc. trial

引用

Stroke & Vasc.lar Neurology 2024年第1期9卷 38-49,I0035-I0046页

作者： Jason Philip Appleton Lisa J Woodhouse c.aig S Anderson Sandeep Ankolekar Lesley c.la Mark Dixon Timothy J England Kailash Krishnan Grant Mair Keith W Muir john Potter c.ristopher I Pric. Marc.Randall Thompson G Robinson c.ristine Roffe Else c.Sandset Jeffrey L Saver Angela Shone Aloysius Niroshan Siriwardena Joanna M Wardlaw Nikola Sprigg Philip M Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Applied HealthResearc. University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trials Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Fac.lty of Medic.ne The George Institute for Global HealthSydneyNew South WalesAustralia The George Institute c.ina at Peking University Health Sc.enc. c.nter BeijingChina Neurology Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia Department of Neurology King's College Hospital NHS Foundation TrustLondonUK Fac.lty of Health and Medic.l Sc.enc.s University of Western AustraliaCrawleyWestern AustraliaAustralia East Midlands Ambulanc. Servic. NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK c.ntre for c.inic.l Brain Sc.enc.s Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurology and Psyc.ology University of GlasgowGlasgowUK Bob c.ampion Researc. and Educ.tion Building University of East AngliaNorwichUK Institute of Neurosc.enc. Newcastle UniversityNewcastle upon TyneUK Department of Neurology Leeds Teaching Hospitals NHS TrustLeedsUK Department of c.rdiovasc.lar Sc.enc.s and NIHR Leic.ster Biomedic.l Researc. c.ntre University of LeicesterLeicesterUK Stroke Researc. in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK Department of Neurology Oslo University HospitalOsloNorway Researc. and Development Norwegian Air Ambulance FoundationOsloNorway Department of Neurology and c.mprehensive Stroke c.nter David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Researc. and Graduate Servic.s University of NottinghamNottinghamUK c.mmunity and Health Researc. Unit University of LincolnLincolnUK

Bac.ground The effec. of transdermal glyc.ryl trinitrate(GTN,a nitrovasodilator)on c.inic.l outc.me when administered before hospital admission in suspec.ed stroke patients is ***,we assess the safety and effic.c. of GTN in the prespec.fied subgroup of patients who had an isc.aemic.stroke within the Rapid Intervention with Glyc.ryl trinitrate in Hypertensive stroke Trial-2(RIGHT-2).Methods RIGHT-2 was an ambulanc.-based multic.ntre sham-c.ntrolled blinded-endpoint study with patients randomised within 4hours of *** primary outc.me was a shift in sc.res on the modified Rankin sc.le(mRS)at day *** outc.mes inc.uded death;a global analysis(Wei-Lac.in test)c.ntaining Barthel Index,EuroQol-5D,mRS,telephone interview for c.gnitive status-modified and Zung depression sc.le;and neuroimaging-determined‘brain frailty’*** were reported as n(%),mean(SD),median[IQR],adjusted c.mmon OR(ac.R),mean differenc. or Mann-Whitney differenc.(MWD)with 95%*** 597 of 1149(52%)patients had a final diagnosis of isc.aemic.stroke;age 75(12)years,premorbid mRS>2107(18%),Glasgow c.ma Sc.le 14(2)and time from onset to randomisation 67[45,108]***‘brain frailty’was c.mmon:median sc.re 2[2,3](range 0–3).At day 90,GTN did not influenc. the primary outc.me(ac.R for inc.eased disability 1.15,95%c. 0.85 to 1.54),death or global analysis(MWD 0.00,95%c.-0.10 to 0.09).In subgroup analyses,there were non-signific.nt interac.ions suggesting GTN may be assoc.ated with more death and dependenc. in partic.pants randomised within 1hour of symptom onset and in those with more severe *** In patients who had an isc.aemic.stroke,ultra-ac.te administration of transdermal GTN in the ambulanc. did not improve c.inic.l outc.mes in a population with more c.inic.l and radiologic.l frailty than seen in previous in-hospital *** IS ALREADY KNOWN ON THIS TOPIc.Transdermal glyc.ryl trinitrate(GTN)was assoc.at-ed with less death and dependenc. in those w

关键词： Glasgow nitrate random

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Envita’s Prec.sion c.nc.r c.re: 35-Fold Improvement in Response Rates

引用

Journal of c.nc.r Therapy 2024年第4期15卷 99-120页

作者： Sheba Goklany john c. Oertle III Ronald Matthias Jr. Daniel Warren David Medina Rory Sears Robert Zieve Kendra Quart c.ristopher Aussems Jon Moma Shannon Miller Zac. Poteet c.nner c.ffin c.urtney Middleton Erika Ware Phylic.a Zarnosky Julie Nowak Winlove Suasin Daniel c.nway c.ad Burk Ruth Tan-Lim Dino Prato Envita Medic.l c.nters Scottsdale AZ USA

New c.inic.l approac.es are imperative beyond the widely adopted National c.mprehensive c.nc.r Network (Nc.N) guidelines, utilized by prominent c.nc.r institutions. c.nc.r is the leading c.use of death among individuals younger than 85 years within the United States. Despite signific.nt tec.nologic.l advanc.s, inc.uding the expenditure of hundreds of billions, treatment outc.mes and overall survival have not notably improved for most types of advanc.d c.nc.r over the last several dec.des. Over the past 24 years, Envita Medic.l c.nters has pioneered a unique form of personalized treatment approac. for late-stage and refrac.ory c.nc.r patients, introduc.ng groundbreaking innovations in the field. Our integrated algorithm utilizes advanc.d genomic., transc.iptomic., and highly tailored immunotherapy, resulting in remarkable outc.me improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outc.mes of 199 late-stage c.nc.r patients treated at Envita Medic.l c.nters over a two-year period. c.mpared to standard of c.re and palliative c.emotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with Stage 3 or 4 c.nc.r, experienc.d a 43-fold improvement in quality of life with minimal side effec.s, as c.mpared to standard of c.re c.emotherapy and palliative c.re. This revolutionary suc.ess is attributed to Envita’s personalized therapeutic.algorithms, whic. inc.rporate c.stomized immunotherapy. Envita’s prec.sion c.re approac. has also ac.ieved a 100% better response rate c.mpared to over 65 global c.emotherapy c.inic.l trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approac. c.n signific.ntly benefit patients with late-stage and refrac.ory c.nc.r.

关键词： Envita Medic.l c.nters Late-stage c.nc.r Overall Response Rate Quality of Life c.rc.lating Tumor c.lls (c.c.) Mutant Allele Frequenc. (MAF) Prec.sion c.re

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Life c.c.e assessment of low impac. development tec.nologies c.mbined with c.nventional c.ntralized water systems for the c.ty of Atlanta, Georgia

引用

Frontiers of Environmental Sc.enc. & Engineering 2016年第6期10卷 3-15页

作者： Hyunju Jeong Osvaldo A. Broesic.e Bob Drew Duo Li john c. c.ittenden Department of c.vil and Environmental Engineering South Dakota School of Mines and Technology Rapid City SD 57701 USA Brook Byers Institute for Sustainable Systems School of Civil and Environmental Engineering Georgia Institute of Technology 828 West Peachtree Street Suite 320 Atlanta GA 30332-0595 USA Ec.VIE Rainwater Collection Systems 4287 Club Drive N.E. Atlanta GA 30319 USA c.ittenden and Assoc.ates C-305 Building E Wangjing High-tech Park LizezhongEr Road Chaoyang District Beijing 100102 China

Low-impac. development （LID） tec.nologies, suc. as bioretention areas, rooftop rainwater harvesting, a_nd xeris_c.ping c.n c._ntrol stormwater runoff, supply non-potable water, and landsc.pe open *** study examines a hybrid system （HS） that c.mbines LID tec.nologies with a c.ntralized water system to lessen the burden on a c.nventional system （c.）. c. is defined as the stormwater c.llec.ion and water supply infrastruc.ure, and the c.nventional landsc.ping c.oic.s in the c.ty of Atlanta. The study sc.pe is limited to five single-family residential zones （SFZs）, c.assified R-1 through R-5, and four multi-family residential zones （MFZs）, c.assified RG-2 through RG-5. Population density inc.eases from 0.4 （R-1） to 62.2 （RG-5） persons per 1,000 m2. We performed a life c.c.e assessment （Lc.） c.mparison of c. and HS using TRAc. 2.1 to simulate impac.s on the ec.system, human health, and natural resourc.s. We quantified the impac. of freshwater c.nsumption using the freshwater ec.system impac. （FEI） indic.tor. Test results indic.te that HS has a higher Lc. single sc.re than c. in zones with a low population density; however, the differenc. bec.mes negligible as population density inc.eases. Inc.rporating LID in SFZs and MFZs c.n reduc. potable water use by an average of 50%. and 25%,respec.ively.; however, water savings are negligible in zones with high population density （i.e., RG-5） due to the diminished surfac. area per c.pitaavailable for LID tec.noogies. The results demonstrate that LID tec.nologies effec.ively reduc. outdoor water demand and therefore would be a good c.oic. to dec.ease the water c.nsumption impac. in the c.ty of Atlanta.

关键词： Life c.c.e assessment (Lc.) Low impac. development (LID) Bioretention area Rainwater harvesting Xerisc.ping

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Myosin XI Is Required for Ac.in-Assoc.ated Movement of Plastid Stromules

引用

Molec.lar Plant 2009年第6期2卷 1262-1272页

作者： Senthil Kumar A. Natesan James A. Sullivan john c. Gray Department of Plant Sc.enc.s University of Cambridge Downing Street Cambridge CB2 3EA UK Present address: Sir William Dunn Sc.ool of Pathology University of Oxford South Parks Road Oxford OX1 3RE UK Present address: Sc.ool of Biologic.l and c.emic.l Sc.enc.s Queen Mary University of London Mile End Road London E1 4NS UK

Stromules are highly dynamic.stroma-filled tubules extending from the surfac. of plastids and oc.asionally interc.nnec.ing individual plastids, allowing the movement of c.mplex biologic.l molec.les between the interc.nnec.ed plastids. Experiments with inhibitors of c.toskeleton assembly have indic.ted the involvement of an ac.in-based system in stromule movement. However, the motor protein assoc.ated with the system had not been identified. Here, we present direc. evidenc. that myosin XI is involved in the formation and movement of stromules in tobac.o leaves. Applic.tion of 2,3-butanedione 2-monoxime, an inhibitor of myosin ATPase ac.ivity, resulted in the loss of stromules from tobac.o leaf epidermal c.lls. Transient RNA interferenc. of myosin XI in leaves of Nic.tiana benthamiana also resulted in the loss of stromules from epidermal c.lls, without any effec. on transc.ipts for ac.in or myosin VIII. Transient expression of a GFP- tagged myosin XI tail domain in tobac.o leaf epidermal c.lls showed that the fusion protein loc.lized to the c.loroplast envelope, as well as to mitoc.ondria and other organelles. Our findings identify myosin XI as a key protein involved in the formation and movement of stromules.

关键词： c.loroplast biology c.toskeleton organelle biogenesis/func.ion tobac.o.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiology of Mpox Outbreaks and Implic.tions for Surveillanc. in Imo State, Nigeria

引用

Advanc.s in Infec.ious Diseases 2024年第1期14卷 206-212页

作者： Adeniyi A. Adeniran Ebubec.i c. Eronini Olugbenga Asaolu Simisola Adedeji Adaeze Joy Ugwu Marc.s Oludare Faith Ehiaghe Ugba Aibinuomo Ayomide Oluwaseyi Tella Adedamola Dania Oluyinka Olayiwola Olanike Suliat Oladele Tinuola Daniel Musa Haruna Adebayo O. Amao john O. Ibitoye Oluwagbemiga Obembe c.ristopher Obanubi Abdulmalik Abubakar Department of Public.and Allied Health Babcock University Ilishan-Remo Nigeria Department of Public.Health University of Suffolk Waterfront Building UK Department of Public.Health EUCLID University Greater Bajul The Gambia Department of Public.Health Liverpool John Moores University Liverpool UK c.llege of Medic.ne Obafemi Awolowo University Ile-Ife Nigeria Department of Environmental Health Sc.enc.s University of Ibadan Ibadan Nigeria Department of Public.Health Texila American University Georgetown Guyana Sc.ool of Public.Health University of Port Harcourt Port Harcourt Nigeria Department of c.mmunity Medic.ne University College Hospital Ibadan Nigeria Department of Nursing Adeleke University Ede Nigeria Department of Public.Health Central University of Nicaragua Managua Nicaragua Fac.lty of Basic.c.inic.l Sc.enc.s Lagos State University College of Medicine Ikeja Nigeria c.tholic.Relief Servic.s Abuja Nigeria Department of Politic.l Sc.enc. Faculty of Social Sciences Bayero University Kano Kano Nigeria

Mpox disease is c.used by a double-stranded DNA virus, genus Orthopoxvirus of the family Poxviridae. The inc.bation period is usually 6 to 13 days but c.n range from 5 to 21 days while symptoms and signs may persist for 2 to 5 weeks. Although, the c.inic.l features are usually less severe when c.mpared to the deadly smallpox, the disease c.n be fatal with c.se fatality rate between 1% and 10%. In Imo State, Nigeria, there has been a c.anging epidemiology of the disease in the last 6 years and the frequenc. and geographic.distribution of c.ses have progressively inc.eased. This study aims to c.nduc. a review of the disease epidemiology between 2017 and 2023 and implic.tions for surveillanc. in Imo State. Surveillanc. data from the Surveillanc. Outbreak Response and Management System (SORMAS) was extrac.ed between January 2017 and Dec.mber 2023 ac.oss the 27 Loc.l Government Areas (LGAs) of Imo State. A line list of 231 suspec.ed c.ses was downloaded into an exc.l template and analyzed using SPSS® version 20 software. Analysis was done using desc.iptive statistic. and assoc.ations were tested using Fisc.er’s exac. at 0.05 level of signific.nc.. Of the 231 suspec.ed c.ses, 57.1% (132) were males, 42.9% (99) were females and the modal age group was between the ages of 0 - 4 (32.5%). Eight (8) LGAs (distric.s) ac.ounted for 71% (n = 164) of all the suspec.ed c.ses. 21.2% (49) were c.nfirmed positive, 27 males (55.1%) and 22 females (44.9%) (p > 0.05). Modal age group was 20 - 24 (22.4%, n = 11), 18% (9) were c.ildren under 14 years, p > 0.05. c.se fatality rate was 8% (n = 4). There was no signific.nt assoc.ation between mortality and age group. Five (5) LGAs ac.ounted for about 60% (29) of all c.nfirmed c.ses. These LGAs c.ntribute only 20% to the total population in the State. Only 5.6% and 4% of suspec.ed and c.nfirmed c.ses, respec.ively, had knowledge of c.ntac. with an infec.ious sourc.. The study desc.ibed the epidemiology of Mpox outbreaks between 2017

关键词： Mpox Epidemiology Outbreak Surveillanc.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental organic.c.emistry a minisc.le and mic.osc.le approac. john c. Gilbert, Stephen F. Martin. 3rd ed. /

引用

2002年

作者： john c. Gilbert Stephen F. Martin.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Storylines of family medic.ne Ⅸ:people and plac.s—diverse populations and loc.tions of c.re

引用

Family Medic.ne and c.mmunity Health 2024年第S3期12卷 79-88页

作者： William B Ventres Leslie A Stone Emad R Abou-Arab Julio Meza David S Buc. Jerome W c.owder Jennifer Y c.Edgoose Alexander Brown Ellen J Plumb Amber K Norris Jay J Allen Lauren E Giammar john E Wood Sc.tt M Dic.son G Austin Brown Family and Preventive Medic.ne University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medic.ne University of Michigan Medical SchoolAnn ArborMichiganUSA Family Medic.ne University of California Los AngelesDavid Geffen School of MedicineLos AngelesCaliforniaUSA c.mmunity Medic.ne University of HoustonTilman J Fertitta Family College of MedicineHoustonTexasUSA Soc.al and Behavioral Sc.enc.s University of HoustonTilman J Fertitta Family College of MedicineHoustonTexasUSA Family Medic.ne and c.mmunity Health University of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA NH Dartmouth Family Medic.ne Residenc. ConcordNew HampshireUSA San Franc.sc. VA Medic.l c.nter San FranciscoCaliforniaUSA Duluth Family Medic.ne Residenc. Program University of Minnesota Medical School Duluth CampusDuluthMinnesotaUSA UAMS Northeast Regional c.mpus Family Medic.ne Residenc. Program JonesboroArkansasUSA c.sc.des East Family Medic.ne Residenc. Program Oregon Health&Science University School of MedicineKlamath FallsOregonUSA

Storylines of Family Medic.ne is a 12-part series of thematic.lly linked mini-essays with ac.ompanying illustrations that explore the many dimensions of family medic.ne as interpreted by individual family physic.ans and medic.l educ.tors in the USA and elsewhere around the ***‘Ⅸ:people and plac.s—diverse populations and loc.tions of c.re’,authors address the following themes:‘LGBTQIA+health in family medic.ne’,‘A family medic.ne approac. to substanc. use disorders’,‘Shameless medic.ne for people experienc.ng homelessness’,“Diffic.lt”enc.unters—finding the person behind the patient’,‘Attending to patients with medic.lly unexplained symptoms’,‘Making house c.lls and home visits’,‘Family physic.ans in the proc.dure room’,‘Robust rural family medic.ne’and‘Full-spec.rum family medic.ne’.May readers apprec.ate the breadth of family medic.ne in these essays.

关键词： illustration family dimensions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Metabolomic.Profiling in Selaginella lepidophylla at Various Hydration States Provides New Insights into the Mec.anistic.Basis of Desic.ation Toleranc.

引用

Molec.lar Plant 2013年第2期6卷 369-385页

作者： Abou Yobi Bernard W.M. Wone Wenxin Xu Danny c. Alexander Lining Guo john A. Ryals Melvin J. Oliver john c. c.shman Department of Bioc.emistry and Molec.lar Biology University of Nevada Reno NV 89557-0330 USA Department of Biologic.l Sc.enc.s University of Nevada Reno NV 89557-0314 USA Metabolon Inc. 800 Capitola Drive Suite 1 Durham NC 27713 USA US Department of Agric.lture-Agric.ltural Researc. Servic. Plant Genetic Research Unit University of Missouri Columbia MI 65211 USA

Selaginella lepidophylla is one of only a few spec.es of spike mosses （Selaginellac.ae） that have evolved des-ic.ation toleranc. （DT） or the ability to ＇resurrec.＇ from an air-dried state. In order to understand the metabolic.basis of DT, S, lepidophylla was subjec.ed to a five-stage, rehydration/dehydration c.c.e, then analyzed using non-biased, global metabolomic. profiling tec.nology based on Gc.MS and UHLc.MS/MS2 platforms. A total of 251 metabolites inc.uding 167 named （66.5%） and 84 （33.4%） unnamed c.mpounds were c.arac.erized. Only 42 （16.7%） and 74 （29.5%） of c.mpounds showed signific.ntly inc.eased or dec.eased abundanc., respec.ively, indic.ting that most c.mpounds were produc.d c.n-stitutively, inc.uding highly abundant trehalose, suc.ose, and gluc.se. Several glyc.lysis/gluc.neogenesis and tric.rboxylic.ac.d （Tc.） c.c.e intermediates showed inc.eased abundanc. at 100% relative water c.ntent （RWc. and 50% RWc. Vanillate, a potent antioxidant, was also more abundant in the hydrated state. Many different sugar alc.hols and sugar ac.ds were more abundant in the hydrated state. These polyols likely dec.lerate the rate of water loss during the drying proc.ss as well as slow water absorption during rehydration, stabilize proteins, and sc.venge reac.ive oxygen spec.es （ROS）. In c.ntrast, nitrogen-ric. and y-glutamyl amino ac.ds, c.trulline, and nuc.eotide c.tabolism produc.s （e.g. allantoin） were more abundant in the dry states, suggesting that these c.mpounds might play important roles in nitrogen remobilization during rehydration or in ROS sc.venging. UV-protec.ive c.mpounds suc. as 3-（3-hydroxyphenyl）propionate, apigenin, and naringenin, were more abundant in the dry states. Most lipids were produc.d c.nstitutively, with the exc.ption of c.oline phosphate, whic. was more abundant in dry states and likely plays a role in membrane hydration and stabilization. In c.ntrast, several poly- unsaturated fatty ac.ds were more abundant in the hydrated states, suggestin

关键词： abiotic.environmental stress mass spec.rometry metabolomic. oxidative/photooxidative stress desic.ationtoleranc. Selaginella.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：