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中国天主教 2006年第5期 9-10页

作者： john L Allen jr 美国天主教报道周报

最近梵蒂冈和中国政府之间就祝圣五位新主教所产生的冲突,媒体普遍认为是世俗政权侵占教宗特权.西方评论家们通常认为,只有教宗享有任命主教的权力(见1月14日'美国天主教周报',以下简称NCR).

关键词：中国政府天主教传统世俗政权梵蒂冈评论家普遍

Recent advances regarding the role of ABC subfamily C member 10(ABCC10) in the efflux of antitumor drugs

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Chinese Journal of Cancer 2014年第5期33卷 223-230页

作者： Rishil J.Kathawala Yi-Jun wang Charles R.Ashby jr.Zhe-Sheng Chen Department of Pharmaceutical Sciences College of Pharmacy and Health SciencesSt.John’s University

ABCC10,also known as multidrug-resistant protein 7(MRP7),is the tenth member of the C subfamily of the ATP-binding cassette(ABC) ***10 mediates multidrug resistance(MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor *** ABCC10 transporter is a 171-kDa protein that is localized on the basolateral cell ***10 is a broad-specificity transporter of xenobiotics,including antitumor drugs,such as taxanes,epothilone B,vinca alkaloids,and cytarabine,as well as modulators of the estrogen pathway,such as *** recent years,ABCC10 inhibitors,including cepharanthine,lapatinib,erlotinib,nilotinib,imatinib,sildenafil,and vardenafil,have been reported to overcome ABCC10-mediated *** review discusses some recent and clinically relevant aspects of the ABCC10 drug efflux transporter from the perspective of current chemotherapy,particularly its inhibition by tyrosine kinase inhibitors and phosphodiesterase type 5 inhibitors.

关键词：抗肿瘤药物家族酪氨酸激酶抑制剂外排多药耐药磷酸二酯酶转运体埃坡霉素

微量元素缺乏症:发展中国营养不均衡、公共卫生影响及防治途径(英文)

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微量元素缺乏症:发展中国营养不均衡、公共卫生影响及防治途径(英...

干涉合成孔径雷达及其在火山研究中的应用(第二部分:阿拉斯加火山的InSAR成像)(英文)

北京论坛（2010）文明的和谐与共同繁荣——为了我们共同的家园：责任与行动

作者： Keith P.west,jr. john Hopkins Bloomberg School of Public Health

Micronutrient deficiencies(MNDs) result from chronic inadequacy in dietary quality that can adversely affect health,development and ***,young children and women of reproductive age in poor,undernourished regions of the developing world are at high risk of *** deficiencies of known public health consequence are those of vitamin A,zinc, iron and *** A deficiency,estimated to affect 190 million children,increases risks of childhood blindness,and mortality by compromising host *** deficiency depresses immunity and increases risks of childhood diarrhea,pneumonia and *** widespread,numbers affected remain difficult to *** deficiency remains the world’s leading cause of anemia,but needs to be identified from other causes to effectively and safely *** deficiency,by its environmental origin,spans the world’s socio-economic gradients,but is proving difficult to prevent in poor *** vitamin and mineral deficiencies form part of the complex syndrome of undernutrition,but their extent,severity or public health consequences remain largely *** and prevention of individual MNDs have historically been motivated by goals to prevent specific,short-acting(eg, xerophthalmia due to vitamin A deficiency) or longer-acting(eg,goiter due to iodine deficiency) clinical ***,it is increasingly clear that mild-to-moderate micronutrient deficiencies can also exact less-specific,short-term(eg increasing severity infections and mortality risk) and longer-acting(eg,mild impairments in cognition,growth and development) tolls on children and *** particular,fetal,post-natal and early childhood exposures to MNDs may increase risks of chronic disease or disability in undernourished settings,discernable by longitudinal ***,despite their public health importance for enabling full human potential,MNDs remain incompletely understood and quantified in most *** represen

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测绘科学 2006年第2期31卷 36-39,51页

作者：路中 Daniel Dzurisin Charles wicks john Power Science Applications International Corporation(SAIC) U.S.Geological Survey Center for EROS USGS Cascades Volcano Observatory USGS Earthquake & Volcano Hazards Programs USGS Alaska Volcano Observatory

干涉合成孔径雷达是一项能够对地表变形进行测量的遥感技术,在一个巨大区域内,它的变形测量精度可达亚厘米级,而其空间分辨率则在数十米以内。本文对我们应用InSAR技术对阿拉斯加火山进行研究的最新成果进行了总结,同时包括火山的喷发... 详细信息

干涉合成孔径雷达是一项能够对地表变形进行测量的遥感技术,在一个巨大区域内,它的变形测量精度可达亚厘米级,而其空间分辨率则在数十米以内。本文对我们应用InSAR技术对阿拉斯加火山进行研究的最新成果进行了总结,同时包括火山的喷发和非喷发活动。这些研究成果表明InSAR不仅能够增进我们对阿拉斯加火山活动的理解,而且还能够增强我们对未来火山喷发情况及其灾害的预测能力。

关键词：干涉合成孔径雷达阿拉斯加火山变形火山测地学

Multiparametric MRI reporting using Prostate Imaging Reporting and Data System version 2.0 (PI-RADSv2) retains clinical efficacy in a predominantly post-biopsy patient population

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Asian Journal of Urology 2019年第3期6卷 256-263页

作者： Edwin Jonathan Aslim Yan Mee Law Puay Hoon Tan john Carson Allen jr.Lionel Tim-Ee Cheng Viswanath Anand Chidambaram Li Yan Khor Benjamin Yongcheng Tan Ernest wencong Eu Christopher wai Sam Cheng john Shyi Peng Yuen Henry Sun Sien Ho Lui Shiong Lee Department of Urology Singapore General HospitalSingapore Department of Diagnostic Radiology Singapore General HospitalSingapore Division of Pathology Singapore General HospitalSingapore Centre of Quantitative Medicine DUKE-NUS Medical SchoolSingapore Department of Anatomical Pathology Singapore General HospitalSingapore

Objective:To evaluate the efficacy of multiparametric magnetic resonance imaging(mp-MRI)using Prostate Imaging Reporting and Data System version 2.0(PI-RADSv2)definitions in detecting organ-confined prostate ***:All patients who underwent radical prostatectomy between January 1,2014 and December 30,2014 were *** underwent mp-MRI within 180 days before *** with prior pelvic irradiation or androgen deprivation therapy were *** embedded,whole-mount histopathology was centrally reviewed and correlated with imaging for tumour location,Gleason score(GS)and ***:There were 39 patients included,of which 35(90%)had mp-MRI done post-biopsy.A total of 93 cancer foci were identified on whole-mount pathology,of which mp-MRI detected 63(68%).Of those detected by mp-MRI,14 were PI-RADS 3(n=6 for GS 6,n=8 for GS 7,no GS≥8)and 49 were PI-RADS 4e5(nZ7 for GS 6,nZ33 for GS 7,and nZ9 for GS≥8).There were 30(32%)cancer foci missed by mp-MRI(n=15 for GS 6,n=13 for GS 7 and n=2 for GS≥8).A lesion classified as PI-RADS 4e5 predicted a higher grade cancer on pathology as compared to PI-RADS 3(for GS 7 lesions,odds ratio[OR]=3.53,95%CI:0.93e13.45,p=0.064).The mp-MRI size detection limit was 20 mm2 and 100 mm2 for 50%and 75%probability of cancer,*** associating with radiological and pathologic stage,the weighted Kappa value was 0.69(pwere 68%(95%CI:57%e77%)and 78%(95%CI:67%e86%),***:In this predominantly post-biopsy cohort,mp-MRI using PI-RADSv2 reporting has a reasonably high diagnostic accuracy in detecting clinically significant prostate cancer.

关键词： Gleason score Histopathology Magnetic resonance imaging Prostatectomy Prostatic cancer

MICROFABRICATED MULTI-ELECTRODE ARRAYS FOR ELECTROCHEMICAL DETECTION IN LAB-ON-A-CHIP DEVICES

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MICROFABRICATED MULTI-ELECTRODE ARRAYS FOR ELECTROCHEMICAL D...

第二届国际传感器科学研讨会

作者： Richard BALDwIN Danielle FRANCO Thomas J. ROUSSEL,jr. Jayadeep GULLAPALLI Mark M. CRAIN Douglas J. JACKSON Robert S. KEYNTON Kevin M.wALSH john F.NABER Department of Chemistry Department of Chemistry Department of Mechanical Engineering Department of Chemistry Department of Electrical and Computer Engineering University of LouisvilleLouisvilleKY 40292USA Department of Electrical and Computer Engineering University of LouisvilleLouisvilleKY 40292USA Department of Mechanical Engineering Department of Electrical and Computer Engineering University of LouisvilleLouisvilleKY 40292USA Department of Electrical and Computer Engineering University of LouisvilleLouisvilleKY 40292USA

＜正＞ One of the dominant themes in analytical instrumentation over the past decade has been the application of microfabrication techniques, common to the electronics industry, to the design and construction of miniaturized "lab-on-a-chip" measurement systems. On the one hand, these devices can consist of sophisticated sample-holding platforms containing hundreds or thousands of microwells to facilitate screening of large sample populations or processing of special kids of samples. On the other, they can emulate complete analytical instruments （or even "labs"） capable of carrying out diverse functions, including not only sample detection but also sample treatment, separation, and collection operations as well. As a result,

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冠状动脉外科的现状

国外医学.心血管疾病分册 1979年第1期 70-71页

作者： john J. Collins jr 麻省波士顿彼得本伯利根医院胸外科主任

我所讲的题目是冠状动脉疾病的外科,而不是心绞痛的治疗,对冠状动脉阻塞性疾病手术治疗的争论,很大一部份是由于把心绞痛作为一种疾病。心绞痛不是一种疾病,仅是疾病的一种症状,实际上约20％心绞痛病人无显著冠状动脉阻塞性疾病。在心... 详细信息

我所讲的题目是冠状动脉疾病的外科,而不是心绞痛的治疗,对冠状动脉阻塞性疾病手术治疗的争论,很大一部份是由于把心绞痛作为一种疾病。心绞痛不是一种疾病,仅是疾病的一种症状,实际上约20％心绞痛病人无显著冠状动脉阻塞性疾病。在心绞痛而无冠状动脉阻塞的病人,其预期寿命正常。Cleveland医院的材料显示,单支血管病变的五年生存率为83.4％,二支血管病变为62.6％,三支血管病变为46.2％,但也有人

关键词：冠状动脉病人手术后心绞痛冠心病外科血管病变

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管理学能力培养取向 9版

An Overview of CyberKnife Radiosurgery

丛书名：管理学系列

2005年

作者：（美）唐·黑尔里格尔（Don Hellriegel）（美）苏珊·E.杰克逊（Susan E. Jackson）（美）小约翰·w.斯洛克姆（john w. Slocum jr.）张燕刘小涛栗晓虹译

本书重点在于对管理能力的培养方面，针对进行管理所必须具备的六种管理能力——沟通、协作、计划和执行、战略行动、全球意识以及自我管理展开了论述。

ISBN: (数字)7508603664

ISBN: (纸本)7508603664

关键词：管理学

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Chinese Journal of Clinical Oncology 2006年第4期3卷 229-243页

作者： john R.Adler Department of Neurosurgery Stanford University Medical School Stanford Jr.

Stereotactic radiosurgery is a non-invasive procedure that utilizes precisely targeted radiation as an ablative surgical tool. Conventional radiosurgery devices, such as the Gamma Knife, rely upon skeletally attached Stereotactic frames to immobilize the patient and precisely determine the 3D spatial position of a tumor. A relatively new instrument, the CyberKnife (Accuray, Inc., Sunnyvale, CA), makes it possible to administer radiosurgery without a frame. The CyberKnife localizes clinical targets using a very accurate image-to-image correlation algorithm, and precisely cross-fires high-energy radiation from a lightweight linear accelerator by means of a highly manipulable robotic arm. CyberKnife radiosurgery is an effective alternative to conventional surgery or radiation therapy for a range of tumors and some non-neoplastic disorders. This report will describe CyberKnife technology and oncologic applications in neurosurgery and throughout the body.

关键词： radiosurgery CyberKnife imaged.-guided tumor ablation stereotactic.

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八十年代全球模型的设计

科学与社会 1981年第4期 41-52页

作者： john M.Richardson,jr.顾为群华盛顿哥伦比亚特区美利坚大学国际事务学院

“人们很难不感受到来自全球模型的一些断言的影响。”当罗马俱乐部以《增长的极限》为题的报告描述第一个全球模型的时候,大多数读者就会体验到这一点。从那时开始,在全球模型方面的进展是很多的;较之在这里对一些现行的重要例子提出... 详细信息

“人们很难不感受到来自全球模型的一些断言的影响。”当罗马俱乐部以《增长的极限》为题的报告描述第一个全球模型的时候,大多数读者就会体验到这一点。从那时开始,在全球模型方面的进展是很多的;较之在这里对一些现行的重要例子提出简要的看法来说,要做的事太多了。这些模型可以分成三大类:国际应用系统分析研究所(II ASA)会议模型、经济模型和有政治倾向的模型。作者认为,在构想更加人道、持久和公平的社会前景时,八十年代的全球模型设计,能够起重要的作用。

关键词：模型设计设计师全球模型八十年代