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Comparison of novel tools with traditional cognitive tests in detecting delirium in elderly medical patients

World Journal of Psychiatry 2020年第4期10卷 46-58页

作者： David J Meagher Henry O’Connell Maeve Leonard Olugbenga Williams Fahad Awan Chris Exton Michael Tenorio Margaret O’Connor Colum P Dunne Walter Cullen john mcfarland Dimitrios Adamis Cognitive Impairment Research Group Graduate Entry Medical SchoolUniversity of LimerickLimerick V94 YVHOIreland Department of Computer Sciences University of LimerickLimerick V94 YVHOIreland School of Medicine University College DublinDublin 4 D04 V1W8Ireland Sligo Mental Health Services BallytivanSligo F91 CD34Ireland

BACKGROUND Efficient detection of delirium and comorbid delirium-dementia is a key diagnostic *** of new,efficient delirium-focused methods of cognitive assessment is a key challenge for improved detection of neurocognitive disorders in everyday clinical *** To compare the accuracy of two novel bedside tests of attention,vigilance and visuospatial function with conventional bedside cognitive tests in identifying delirium in older hospitalized *** 180 consecutive elderly medical inpatients(mean age 79.6±7.2;51%female)referred to a psychiatry for later life consultation-liaison service with delirium,dementia,comorbid delirium-dementia and cognitively intact *** were assessed cross-sectionally with conventional bedside cognitive tests[WORLD,Months Backward test(MBT),Spatial span,Vigilance A and B,Clock Drawing test and Interlocking Pentagons test]and two novel cognitive tests[Lighthouse test,Letter and Shape Drawing test(LSD)-4].RESULTS Neurocognitive diagnoses were delirium(n=44),dementia(n=30),comorbid delirium-dementia(n=60)and no neurocognitive disorder(n=46).All conventional tests had sensitivity of>70%for delirium,with best overall accuracy for the Vigilance-B(78.3%),Vigilance-A(77.8%)and MBT(76.7%)*** sustained attention component of the Lighthouse test was the most distinguishing of delirium(sensitivity 84.6%;overall accuracy 75.6%).The LSD-4 had sensitivity of 74.0%and overall accuracy 74.4%for delirium *** tests allowed for enhanced sensitivity(>90%)and overall accuracy(≥75%)with the highest overall accuracy for the combination of MBT-Vigilance A and the combined Vigilance A and B tests(both 78.3%).When analyses were repeated for those with dementia,there were similar findings with the MBTVigilance A the most accurate overall combination(80.0%).Combining the Lighthouse-SA with the LSD-4,a fail in either test had sensitivity for delirium of 91.4 with overall accuracy of 74.4%.

关键词： Visuospatial function Attention Vigilance Letter and Shape Drawing test Lighthouse test Delirium Dementia Phenomenology Assessment

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内部销售,挑战“三向”法则

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经理人 2005年第3期 52-53页

作者： Jennifer mcfarland 连青松

1994年，IBM公司的太卫?格罗斯曼(David Gtossman)和约翰·派屈里克(john Patrick)确信，“蓝色巨人”必须参与互联网革命。由于地盘争斗严重削弱其能力，并且面临150亿美元的累计亏损，另加最佳领导人转投电子资讯系统公司和安达信咨... 详细信息

1994年，IBM公司的太卫?格罗斯曼(David Gtossman)和约翰·派屈里克(john Patrick)确信，“蓝色巨人”必须参与互联网革命。由于地盘争斗严重削弱其能力，并且面临150亿美元的累计亏损，另加最佳领导人转投电子资讯系统公司和安达信咨询公司等类似企业，“蓝色巨人”当时已威为“企业懒散的代名词”。

关键词：企业内部销售安达信亏损美元 IBM公司领导人格罗斯曼争斗代名词

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Effect of Stabilized Fish Oil Source on Sperm Quality and Production of Boars

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Open Journal of Animal Sciences 2021年第2期11卷 197-207页

作者： Michael Andrew Parsley Mark Elder Wilson Thomas john Gall Mark Richard Malcolm Ballard Feedworks USA Ltd. Cincinnati USA Wilson Consulting Service McFarland USA Gall Consulting Service Burlington USA The Ballard Group Inc. Cincinnati USA

Research findings for supplementing boar stud diets with fish oils are inconsistent. This study was designed to address three possible causes of performance variation of boars to fish oil supplementation: stability of the fatty acid source, level of inclusion and breed of boars tested. Three groups of 87 boars each, from two genetic lines (PIC 337 and PIC 800), were assigned to treatment based on age, mean sperm production (previous 12 weeks), and body condition score. All boars received a corn-soybean meal diet with a commercial fish oil supplement providing 1.83 g/boar/day of docosahexaenoic acid (DHA) as a preconditioning diet. On 10-Aug., 2020, the DHA source was changed to a stabilized starch imbedded source of refined fish oil (Salmate®), providing 1.83 g/b/d for the test diet. Two additional levels providing 2.38 and 2.94 g/b/d of DHA were fed for a 9 week pretreatment period and during the test period. Salmate® fed at 2.38 g/b/d of DHA resulted in a reduction in the number of rejected ejaculates (P 0.045) by 7.5% and 6.4% compared to the lowest and highest inclusion rates, respectively. There were no treatments by genetic line interactions. A retrospective study of semen production and quality of 77 boars on the Salmate® diet containing 1.83

关键词： Boars Docosahexaenoic Acid (DHA) Salmate® Total Sperm Semen Doses

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