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Helicobacter pylori:High dose amoxicillin does not improve primary or secondary eradication rates in an Irish cohort

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World Journal of Clinical Cases 2024年第16期12卷 2773-2779页

作者： Conor Costigan Aoife m O'Sullivan Jim O'Connell Shreyashee Sengupta Thomas Butler Stephen molloy Fintan john O'Hara Barbara Ryan Niall Breslin Sarah O'Donnell Anthony O'Connor Sinead Smith Deirdre mcNamara Trinity Academic Gastroenterology Group School of Medicine-Trinity College DublinDublin D2Ireland Department of Gastroenterology Tallaght University HospitalDublin D24 NR0AIreland

BACKGROUND Helicobacter pylori(***)eradication rates have fallen globally,likely in large part due to increasing antibiotic resistance to traditional *** areas of high clarithromycin and metronidazole resistance such as ours,maastricht VI guidelines suggest high dose amoxicillin dual therapy(HDADT)can be considered,subject to evidence for local *** this study we assess efficacy of HDADT therapy for *** eradication in an Irish *** To assess the efficacy of HDADT therapy for *** eradication in an Irish cohort as both first line,and subsequent therapy for patients diagnosed with *** All patients testing positive for *** in a tertiary centre were treated prospectively with HDADT(amoxicillin 1 g tid and esomeprazole 40 mg bid×14 d)over a period of 8 *** was confirmed with Urea Breath Test at least 4 wk after cessation of therapy.A delta-over-baseline>4%was considered *** demographics and treatment outcomes were recorded,analysed and controlled for basic demographics and prior *** *** One hundred and ninety-eight patients were identified with *** infection,10 patients were excluded due to penicillin allergy and 38 patients refused follow up *** all 139 were included in the analysis,55%(n=76)were female,mean age was 46.6 ***,93(67%)of patients were treatment-naïve and 46(33%)had received at least one previous course of *** groups were statistically ***-reported compliance with HDADT was 97%,mild side-effects occurred in 7%.There were no serious adverse drug *** the eradication rate for our cohort was 56%(78/139).eradication rates were worse for those with previous treatment[43%(20/46)vs 62%(58/93),P=0.0458,odds ratio=2.15].Age and Gender had no effect on eradication *** Overall eradication rates with HDADT were *** being a simple and possibly better tolerated regime,these results do not

关键词： Helicobacter pylori eradication Helicobacter pylori High dose amoxicillin High dose amoxicillin dual therapy Triple therapy

Synthesis of LiSm_(0.01)mn_(1.99)O_4 by molten salt technique

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Journal of Rare Earths 2010年第2期28卷 255-259页

作者： m Helan L john Berchmans Department of Chemistry Jamal Mohamed College (Autonomous) Electropyrometallurgy Division Central Electrochemical Research Institute

Samarium substituted lithium manganese oxide powders were successfully prepared by molten-salt synthesis(mSS) using eutectic mixture of LiCl,SmCl3.6H2O and mnO2 salt at 700 °*** synthesis was carried out in open *** crystalline powders were characterized for their phase identification using X-ray diffraction(XRD) *** physico-chemical properties of the samarium substituted lithium manganese oxide powders were investigated by thermal analysis(TGA/DTA),FT-IR spectroscopy,EDAX,electron par...

关键词： LiSm0.01mn1.99O4 molten salt synthesis cathode materials rare earth ion

Fuzzy modeling of Surficial Uranium Prospectivity in British Columbia(Canada)with a Weighted Fuzzy Algebraic Sum Operator

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Journal of Earth Science 2021年第2期32卷 293-309页

作者： Emmanuel john m.Carranza School of Agricultural Earth and Environmental SciencesUniversity of KwaZulu-NatalWestville CampusDurban 4041South Africa

This paper demonstrates knowledge-guided fuzzy logic modeling of regional-scale surficial uranium(U)prospectivity in British Columbia(Canada).The deposits/occurrences of surficial U in this region vary from those in Western Australia and Namibia;thus,requiring innovative and carefully-thought techniques of spatial evidence generation and *** novelty,this papers introduces a new weighted fuzzy algebraic sum operator to combine certain spatial evidence *** analysis trialed several layers of spatial evidence based on conceptual mineral system model of surficial U in British Columbia(Canada)as well as tested various models of evidence ***-linear weighted functions of(a)spatial closeness to U-enriched felsic igneous rocks was employed as U-source spatial evidence,(b)spatial closeness to paleochannels as fluid pathways spatial evidence,and(c)surface water U content as chemical trap spatial *** best models of prospectivity created by integrating the layers of spatial evidence for U-source,pathways and traps predicted at least 85%of the known surficial U deposits/occurrences in>10%of the study region with the highest prospectivity fuzzy *** results of analyses demonstrate that,employing the known deposits/occurrences of surficial U for scrutinizing the spatial evidence layers and the final models of prospectivity can pinpoint the most suitable critical processes and models of data integration to reduce bias in the analysis of mineral prospectivity.

关键词： fuzzy logic mineral systems surficial uranium fuzzy algebraic sum

Sorption and phase distribution of ethanol and butanol blended gasoline vapours in the vadose zone after release

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Journal of Environmental Sciences 2014年第3期26卷 608-616页

作者： Ejikeme Ugwoha john m. Andresen Chemical and Environmental Engineering University of Nottingham School of Engineering and Physical Sciences Heriot-Watt University

The sorption and phase distribution of 20% ethanol and butanol blended gasoline （E20 and B20） vapours have been examined in soils with varying soil organic matter （SOm） and water contents via laboratory microcosm experiments. The presence of 20% alcohol reduced the sorption of gasoline compounds by soil as well as the mass distribution of the compounds to soil solids. This effect was greater for ethanol than butanol. Compared with the sorption coefficient （Kd） of unblended gasoline compounds, the Kd of E20 gasoline compounds decreased by 54% for pentane, 54% for methylcyclopentane （mCP） and 63% for benzene, while the Kd of B20 gasoline compounds decreased by 39% for pentane, 38% for mCP and 49% for benzene, The retardation factor （R） of E20 gasoline compounds decreased by 53% for pentane, 53% for mCP and 48% for benzene, while the R of B20 gasoline compounds decreased by 39% for pentane, 37% for mCP and 38% for benzene. For all SOm and water contents tested, the Kd and R of all gasoline compounds were in the order of unblended gasoline 〉 B20 〉 E20, indicating that the use of high ethanol volume in gasoline to combat climate change could put the groundwater at greater risk of contamination,

关键词： butanol-blended gasoline ethanol-blended gasoline phase distribution soil organic matter soil water content sorption vadose zone

Host RNA circles and the origin of hepatitis delta virus

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World Journal of Gastroenterology 2014年第11期20卷 2971-2978页

作者： john m Taylor Fox Chase Cancer Center PhiladelphiaPA 19111United States

Recent reports show that many cellular RNAs are processed to form circular species that are relatively abundant and resistant to host *** some cases,such circles actually bind host *** depletion of available microRNAs appears to have biological roles;for instance,in homeostasis and *** findings regarding host RNA circles support a speculative reappraisal of the origin and mode of replication of hepatitis delta virus,hepatitis delta virus(HDV),an agent with a small circular RNA genome;specifically,it is proposed that in hepatocytes infected with hepatitis B virus(HBV),some viral RNA species are processed to circular forms,which by a series of chance events lead to an RNA that can be both replicated by host enzymes and assembled,using HBV envelope proteins,to form particles some of which are *** a model also may provide some new insights into the potential pathogenic potential of HDV *** return,new insights into HDV might provide information leading to a better understanding of the roles of the host RNA circles.

关键词： Hepatitis B virus Hepatitis delta virus Circular RNA Ribozymes microRNA

The GPPS HI survey——A deeper view of the milky Way galaxy

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Science China(Physics,mechanics & Astronomy) 2022年第12期65卷 68-69页

作者： john m.Dickey School of Natural Sciences University of TasmaniaHobart Tas 7001Australia

The paper in this volume by Hong et al.[1]describing a new survey of the radio frequency spectral line of hydrogen,that astronomers call the HI line,shows some dramatic images of the milky Way *** Five-hundred-meter Aperture Spherical radio Telescope,FAST,has done this survey as part of the Galactic Plane Pulsar Snapshot(GPPS)Survey[2].

关键词： GPPS galaxy survey

Two-photon polymerization lithography for imaging optics

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International Journal of Extreme manufacturing 2024年第4期6卷 21-60页

作者： Hao Wang Cheng-Feng Pan Chi Li Kishan S menghrajani markus A Schmidt Aoling Li Fu Fan Yu Zhou Wang Zhang Hongtao Wang Parvathi Nair Suseela Nair john You En Chan Tomohiro mori Yueqiang Hu Guangwei Hu Stefan A maier Haoran Ren Huigao Duan Joel K W Yang College of mechanical and Vehicle Engineering Hunan UniversityChangsha 410082People's Republic of China Engineering Product Development Singapore University of Technology and DesignSingapore 487372Singapore Greater Bay Area Institute for Innovation Hunan UniversityGuangzhou 511300People's Republic of China Department of Electrical and Computer Engineering National University of Singapore4 Engineering Drive 3Singapore 117576Singapore School of Physics and Astronomy Faculty of ScienceMonash UniversityMelbourneVictoria 3800Australia Leibniz Institute of Photonic Technology 07745 JenaGermany Abbe Center of Photonics and Faculty of Physics FSU Jena07745 JenaGermany Otto Schott Institute of material Research FSU Jena07745 JenaGermany Institute of materials Research and Engineering A*STAR(Agency for Science Technology and Research)Singapore 138634Singapore Industrial Technology Center of Wakayama Prefecture Wakayama 6496261Japan School of Electrical and Electronic Engineering Nanyang Technological UniversitySingapore639798Singapore Department of Physics Imperial College LondonLondon SW72AZUnited Kingdom

Optical imaging systems have greatly extended human visual capabilities,enabling the observation and understanding of diverse *** technologies span a broad spectrum of wavelengths from x-ray to radio frequencies and impact research activities and our daily *** glass lenses are fabricated through a series of complex processes,while polymers offer versatility and ease of ***,modern applications often require complex lens assemblies,driving the need for miniaturization and advanced designs with micro-and nanoscale features to surpass the capabilities of traditional fabrication ***-dimensional(3D)printing,or additive manufacturing,presents a solution to these challenges with benefits of rapid prototyping,customized geometries,and efficient production,particularly suited for miniaturized optical imaging *** 3D printing methods have demonstrated advantages over traditional counterparts,yet challenges remain in achieving nanoscale ***-photon polymerization lithography(TPL),a nanoscale 3D printing technique,enables the fabrication of intricate structures beyond the optical diffraction limit via the nonlinear process of two-photon absorption within liquid *** offers unprecedented abilities,***-free fabrication,micro-and nanoscale capabilities,and rapid prototyping of almost arbitrary complex 3D *** this review,we emphasize the importance of the criteria for optical performance evaluation of imaging devices,discuss material properties relevant to TPL,fabrication techniques,and highlight the application of TPL in optical *** the first panoramic review on this topic,it will equip researchers with foundational knowledge and recent advancements of TPL for imaging optics,promoting a deeper understanding of the *** leveraging on its high-resolution capability,extensive material range,and true 3D processing,alongside advances in materials,fabrication,and design,we en

关键词： two-photon polymerization lithography 3D printing additive manufacturing imaging optics and nanophotonics

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m7设计与文化中心卡塔尔多哈

世界建筑导报 2024年第4期39卷 84-86页

作者： john mcAslan + Partners 约翰•麦卡兰建筑事务所

由约翰·麦卡兰建筑事务所最新设计的m7设计与文化中心位于多哈,是占地2万平方米的msheire区综合开放项目的建筑主体。这一建筑项目也正在改变卡塔尔首都市民的生活方式。该设计与文化中心最近被命名为m7,已成为卡塔尔时尚设计行业的创... 详细信息

由约翰·麦卡兰建筑事务所最新设计的m7设计与文化中心位于多哈,是占地2万平方米的msheire区综合开放项目的建筑主体。这一建筑项目也正在改变卡塔尔首都市民的生活方式。该设计与文化中心最近被命名为m7,已成为卡塔尔时尚设计行业的创意中心以及该地区创新创业的公共展示区。

关键词：建筑事务所建筑主体创新创业时尚设计首都市民最新设计展示区卡塔尔

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Evaluation of a Wireless Solar Powered Personal Weather Station

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Agricultural Sciences 2024年第1期15卷 36-53页

作者： Robert J. Lascano Timothy S. Goebel Dennis C. Gitz III john E. Stout Cropping Systems Research Laboratory Wind Erosion and Water Conservation Research Unit USDA-ARS Lubbock TX USA

We are evaluating dryland cotton production in martin County, Texas, measuring cotton lint yield per unit of rainfall. Our goal is to collect rainfall data per 250 - 400 ha. Upon selection of a rainfall gauge, we realized that the cost of using, for example, a tipping bucket-type rain gauge would be too expensive and thus searched for an alternative method. We selected an all-in-one commercially available weather station;hereafter, referred to as a Personal Weather Station (PWS) that is both wireless and solar powered. Our objective was to evaluate average measurements of rainfall obtained with the PWS and to compare these to measurements obtained with an automatic weather station (AWS). For this purpose, we installed four PWS deployed within 20 m of the Plant Stress and Water Conservation meteorological Tower that was used as our AWS, located at USDA-ARS Cropping Systems Research Laboratory, Lubbock, TX. In addition, we measured and compared hourly average values of short-wave irradiance (Rg), air temperature (Tair) and relative humidity (RH), and wind speed (WS), and calculated values of dewpoint temperature (Tdew). This comparison was done over a 242-day period (1 October 2022-31 may 2023) and results indicated that there was no statistical difference in measurements of rainfall between the PWS and AWS. Hourly average values of Rg measured with the PWS and AWS agreed on clear days, but PWS measurements were higher on cloudy days. There was no statistical difference between PWS and AWS hourly average measurements of Tair, RH, and calculated Tdew. Hourly average measurements of Rg and WS were more variable. We concluded that the PWS we selected will provide adequate values of rainfall and other weather variables to meet our goal of evaluating dryland cotton lint yield per unit rainfall.

关键词： Automation Sensors Citizen Weather Station mesonet Rainfall Weather Variables