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Building Simulation 2023年第2期16卷 243-261页

作者： Murtaza Mohammadi Paige Wenbin Tien john kaiser calautit Department of Architecture and Built Environment University of NottinghamNottinghamUK

Skygardens or skycourts are a unique architectural intervention in the built environment,enhancing the social,economic,and environmental values of the *** allows occupants to connect and experience outdoor freshness within a semi-enclosed ***,skygardens located on a highrise building may generate intense wind gusts,endangering the safety of *** a validated computational fluid dynamics model,this study investigates the potential of various vegetative barriers or shelterbelts in attenuating the high wind speeds encountered in such spaces and the impact on wind and thermal *** skygarden configurations were investigated with and without vegetative barriers,simplified and modelled as porous zones,and their effect was studied on the velocity and temperature profile at the occupants’*** results indicate that while hedges and trees can offer resistance to airflow,trees provide higher temperature ***,a combination of vegetative and geometrical barriers provides the most optimal condition in the *** study has identified the importance of assessing wind attenuation characteristics of tree plantations on highrise skygarden,and the results can be used in designing intervention ***,vegetation can attenuate pollutants and mitigate poor air quality by surface deposition,and future studies should investigate in that direction.

关键词： built environment computational fluid dynamics(CFD) wind comfort thermal comfort skygarden

Machine Learning and Deep Learning Methods for Enhancing Building Energy Efficiency and Indoor Environmental Quality – A Review

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能源与人工智能(英文) 2022年第4期10卷 262-289页

作者： Paige Wenbin Tien Shuangyu Wei Jo Darkwa Christopher Wood john kaiser calautit Department of Architecture and Built Environment University of NottinghamNottingham NG72RDUK

The built environment sector is responsible for almost one-third of the world’s final energy consumption. Hence, seeking plausible solutions to minimise building energy demands and mitigate adverse environmental impacts is necessary. Artificial intelligence (AI) techniques such as machine and deep learning have been increasingly and successfully applied to develop solutions for the built environment. This review provided a critical summary of the existing literature on the machine and deep learning methods for the built environment over the past decade, with special reference to holistic approaches. Different AI-based techniques employed to resolve interconnected problems related to heating, ventilation and air conditioning (HVAC) systems and enhance building performances were reviewed, including energy forecasting and management, indoor air quality and occupancy comfort/satisfaction prediction, occupancy detection and recognition, and fault detection and diagnosis. The present study explored existing AI-based techniques focusing on the framework, methodology, and performance. The literature highlighted that selecting the most suitable machine learning and deep learning model for solving a problem could be challenging. The recent explosive growth experienced by the research area has led to hundreds of machine learning algorithms being applied to building performance-related studies. The literature showed that existing research studies considered a wide range of scope/scales (from an HVAC component to urban areas) and time scales (minute to year). This makes it difficult to find an optimal algorithm for a specific task or case. The studies also employed a wide range of evaluation metrics, adding to the challenge. Further developments and more specific guidelines are required for the built environment field to encourage best practices in evaluating and selecting models. The literature also showed that while machine and deep learning had been successfully applied in

关键词： Artificial intelligence Building energy management Deep learning Heating,ventilation and air conditioning (HVAC) Indoor environmental quality(IEQ) Machine learning Occupancy detection Thermal comfort

Development of an Enhanced Self-Tuning RBF-PID Controller for Achieving Higher Energy-Efficient Process Control

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Journal of Building Construction and Planning Research 2021年第4期9卷 272-291页

作者： Zu Wang Liang Xia john kaiser calautit Xinru Wang Danwei Jiang Song Pan Jinshun Wu Research Centre for Fluids and Thermal Engineering University of Nottingham Ningbo China Department of Architecture and Built Environment The University of Nottingham Nottingham UK College of Emergency Technology and Management North China Institute of Science & Technology Langfang China Beijing Key Laboratory of Green Built Environment and Energy Efficient Technology Beijing University of Technology Beijing China Hebei Province Renewable Energy Heating and Cooling Cogeneration International Union Research Center North China Institute of Science & Technology Langfang China

Proportional, integral and derivative (PID) control strategy has been widely applied in heating systems in decades. To improve the accuracy and the robustness of PID control, self-tuning radial-basis-function neural network PID (RBF-PID) is developed and used. Even though being popular, during the control process both of PID and RBF-PID control strategy are inadequate in achieving simultaneous high energy-efficiency and good control accuracy. To address this problem, in this paper we develop and report an enhanced self-tuning radial-basis-function neural network PID (e-RBF-PID) controller. To identify the superiority of e-RBF-PID, following works are conducted and reported in this paper. Firstly, four controllers, i.e., on-off, PID, RBF-PID and e-RBF-PID are designed. Secondly, in order to test the performance of the e-RBF-PID controller, an experimental water heating system is constructed for being controlled. Finally, the energy consumption for the four controllers under the three control scenarios is investigated through experiments. The experimental results indicate that in the three scenarios, the developed e-RBF-PID controller outperforms on-off controller as having higher accuracy. Compared to the PID controller, the e-RBF-PID controller has higher speed in control, and the experimental results show that settling time savings is between 12.6% - 49.0%. Most importantly, less control energy consumption is obtained if using the e-RBF-PID controller. It is found that up to 28.5% energy consumption can be saved. Therefore, it is concluded that the proposed e-RBF-PID is capable of enhancing energy efficiency during control process.

关键词： Energy-Efficient Control RBF Neural Network Enhanced Self-Tuning PID Experimental Validation

Social media video analysis methodology for sarin exposure

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Forensic Sciences Research 2022年第2期7卷 279-284页

作者： Sadik Toprak Emine Yilmaz Can Bulent Altinsoy john Hart Zekeriya Dogan Mustafa Ozcetin Department of Forensic Medicine Istanbul UniversityIstanbulTurkey Department of Medical Pharmacology Bulent Ecevit UniversityZonguldakTurkey Department of Pulmonary Medicine Bulent Ecevit UniversityZonguldakTurkey James Martin Center for Nonproliferation Studies MontereyCAUSA Department of Civil Engineering Bulent Ecevit UniversityZonguldakTurkey Department of Pediatrics Istanbul UniversityIstanbulTurkey

As social media becomes increasingly ubiquitous,many events are recorded and released on social media platforms,including chemical weapon *** develop an objective tool in order to evaluate brief and unstructured social media videos for analysing sarin exposure from a civilian medical pathology *** developed and validated this new questionnaire using a standardized procedure that includes content domain specification,item pool generation,content validity evaluation,a pilot study,and assessment of reliability and *** total,51 sarin attacks and 48 matched videos were ***’s a for all 20 items was 0.75,which indicates adequate internal *** test–retest reliability was 0.96,which indicates good internal *** inter-observer intraclass correlation coefficient was *** verifying sampling adequacy with the kaiser–Meyer–Olkin measure and the factorability of the items with Barlett’s test of sphericity,a factor analysis was *** to the principal axis factoring,a six-factor solution explained 51.86%of the total *** receiver-operating characteristic curve analysis showed that the Video Score Questionnaire has a sensitivity of 0.817,a specificity of 0.478,and an efficiency of ***,the Video Score Questionnaire is reliable and valid for evaluating sarin attacks from brief and unstructured social media videos.

关键词： Forensic sciences social media sarin scale questionnaire chemical weapon nerve agent YouTube

The Response to Arbitrarily Bandlimited Gaussian Noise of the Complex Stretch Processor Using a Conventional Range-Sidelobe-Reduction Window

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Journal of Signal and Information Processing 2018年第1期9卷 36-62页

作者： john N. Spitzmiller Simulation & Integration Services Parsons Government Services Inc. Huntsville AL USA

This paper derives a mathematical description of the complex stretch processor’s response to bandlimited Gaussian noise having arbitrary center frequency and bandwidth. The description of the complex stretch processor’s random output comprises highly accurate closed-form approximations for the probability density function and the autocorrelation function. The solution supports the complex stretch processor’s usage of any conventional range-sidelobe-reduction window. The paper then identifies two practical applications of the derived description. Digital-simulation results for the two identified applications, assuming the complex stretch processor uses the rectangular, Hamming, Blackman, or kaiser window, verify the derivation’s correctness through favorable comparison to the theoretically predicted behavior.

关键词： Stretch Processing Noise Jamming Bandlimited Gaussian Noise Range-Sidelobe-Reduction Windows

Histologic patterns of liver injury induced by anti-PD-1 therapy

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Gastroenterology Report 2020年第1期8卷 50-55,I0002页

作者： Dongwei Zhang john Hart Xianzhong Ding Xuchen Zhang Michael Feely Lindsay Yassan Lindsay Alpert Consuelo Soldevila-Pico Xuefeng Zhang Xiuli Liu Jinping Lai Department of Pathology Immunology and Laboratory of MedicineUniversity of Florida College of MedicineGainesvilleFLUSA Department of Pathology and Laboratory Medicine University of Rochester Medical CenterRochesterNYUSA Department of Pathology University of Chicago Pritzker School of MedicineChicagoILUSA Department of Pathology and Laboratory of Medicine Loyola University Medical CenterMaywoodILUSA Department of Pathology Yale School of MedicineNew HavenCTUSA Department of Medicine University of Florida College of MedicineGainesvilleFLUSA Department of Pathology Duke University Medical CenterDurhamNCUSA Department of Pathology Kaiser Permanente Sacramento Medical CenterSacramentoCAUSA

Background:Nivolumab and pembrolizumab—two monoclonal antibodies that block human programmed cell death-1(PD-1)—have been successfully used to treat patients with multiple advanced *** histologic patterns of hepatic toxicity induced by anti-PD-1 treatment have not been well studied and the aim of this study was to explore ***:Eight patients with advanced malignancies who were treated with either nivolumab or pembrolizumab were identified from five *** patients had no history of underlying liver disease and a viral hepatitis panel was negative in all ***:Seven of eight patients exhibited mild to moderate gastrointestinal symptoms such as abdominal pain,fatigue,nausea,vomiting,and jaundice after anti-PD-1 *** elevations in liver-chemistry tests were detected in all *** cases(6/8)demonstrated an acute lobular hepatitis pattern of histologic *** remaining two cases showed different histologic patterns of injury:steatohepatitis with mild cholestasis(1/8)and pure acute cholestatic injury(1/8).No case showed typical features of autoimmune *** liver function recovered in all eight cases after cessation of anti-PD-1 agents and with immunosuppressive ***:Our study suggests that screening patients for abnormal liver-function tests prior to anti-PD-1 therapy as well as periodic monitoring of liver-function tests are necessary to prevent severe liver *** than causing classical autoimmune hepatitis,PD-1 inhibitors appear to produce an immune-mediated nonspecific acute *** cessation,without steroid therapy,may therefore be sufficient in some patients.

关键词： nivolumab pembrolizumab anti-PD-1 liver injury histology hepatitis

Implementation science for the adductor canal block:A new and adaptable methodology process

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World Journal of Orthopedics 2021年第11期12卷 899-908页

作者： Nikhil Crain Chun-Yuan Qiu Stephen Moy Shawn Thomas Vu Thuy Nguyen Mijin Lee-Brown Diana Laplace Jennifer Naughton john Morkos Vimal Desai Bowman Gray Center for Medical Education Wake Forest School of MedicineWinston-SalemNC 27103United States Perioperative Service and Anesthesiology Kaiser Permanente Medical CenterBaldwin ParkCA 91706United States Department of Anesthesiology Baldwin Park Medical CenterSouthern California Kaiser Permanente Medical GroupBaldwin ParkCA 91706United States johns Hopkins University The Johns Hopkins University School of MedicineBaltimoreMD 21205United States

BACKGROUND Following the successful Perioperative Surgical Home(PSH)practice for total knee arthroplasty(TKA)at our institution,the need for continuous improvement was realized,including the deimplementation of antiquated PSH elements and introduction of new *** To investigate the transition from femoral nerve blocks(FNB)to adductor canal nerve blocks(ACB)during *** Our 13-month study from June 2016 to 2017 was divided into four periods:a three-month baseline(103 patients),a one-month pilot(47 patients),a three-month implementation and hardwiring period(100 patients),and a six-month evaluation period(185 patients).In total,435 subjects were *** within 30 postoperative days were extracted from electronic medical records,such as physical therapy results and administration of oral morphine equivalents(OME).RESULTS Our institution reduced FNB application(64% to 3%)and increased ACB utilization(36% to 97%)at 10 *** in the ACB group were found to have increased ambulation on the day of surgery(4.1 vs 2.0 m)and lower incidence of falls(0 vs 1%)and buckling(5% vs 27%)compared with FNB patients(P<0.05).While ACB patients(13.9)reported lower OME than FNB patients(15.9),the difference(P=0.087)did not fall below our designated statistical threshold of P value<*** By demonstrating closure of the“knowledge to action gap”within 6 mo,our institution’s findings demonstrate evidence in the value of implementation *** education,technical support,and performance monitoring were deemed key facilitators of our program’s *** patient populations and additional orthopedic procedures are recommended for future study.

关键词： Total knee arthroplasty Femoral nerve block Adductor canal block Physical therapy Oral morphine equivalent Action-related information gap

First Metatarsophalangeal Joint Arthrodesis: Comparison of Mesenchymal Stem Cell Allograft versus Autogenous Bone Graft Fusion Rates

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Surgical Science 2013年第5期4卷 263-267页

作者： john Anderson Nathan Jeppesen Myron Hansen Chad Brady Adam Gough Zflan Fowler Alamogordo Orthopaedics Alamogordo USA Cactus Foot and Ankle Gilbert USA Gila Regional Medical Center Silver City USA Presbyterian Albuquerque USA Scripps Mercy-kaiser Hospital San Diego USA

With patients undergoing first time 1st metatarsophalangeal joint arthrodesis using graft material when it was required to fill cystic bone voids, we retrospectively compared the time to fusion (clinical and radiographic), and non-union rate between the patient’s own bone autograft (n = 62) versus a mesenchymal stem cell impregnated allograft group (n = 51). A third control group (n = 52) was included in which an end-to-end arthrodesis was performed and no graft interposition was used or necessary. The non-union rate was 4% (n = 2) in the control group, 5.9% (n = 4) in the autograft group, and 9.5% (n = 5) in the mesenchymal stem cell allograft group. The time for radiographic fusion was 6.46 weeks for the control group, 6.52 weeks for the autograft group, and 6.53 weeks for the mesenchymal stem cell allograft group. The difference in time to clinical and radiographic union and the non-union rate were not found to be statistically significant among all 3 groups. Patient comorbidities and their possible effects on union rates were also analyzed within the populations. Some comorbidities had statistically significantly non-unions within the population, notably smoking (p = 0.024) and Rheumatoid arthritis (p = 0.001), however the populations were fairly small. The use of allogeneic bone graft impregnated with mesenchymal stem cells yields a similar fusion rate as with the use of autologous bone graft harvested from the surrounding area. The allograft impregnated with mesenchymal stem cells is a viable alternative yielding similar results when local autogenous bone graft is not available, not obtainable, or conditions warrant its use.

关键词： Metatarsophalangeal Joint Bone Autograft Mesenchymal Stem Cell

Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity

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Molecular Plant 2022年第3期15卷 520-536页

作者： Genevieve Hoopes Xiaoxi Meng john P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers Department of Plant Biology Michigan State UniversityEast LansingMI 48824USA Department of Horticultural Science University of MinnesotaSt.PaulMN 55108USA Department of Plant Science McGill UniversitySainte-Anne-de-BellevueQC H9X 3V9Canada Plant Breeding Wageningen University&ResearchPlant Breeding6708 PB Wageningenthe Netherlands IBG-4 Bioinformatics Forschungszentrum JülichWilhelm Johnen Str52428 JülichGermany Department of Plant Soiland Microbial SciencesMichigan State UniversityEast LansingMI 48824USA Bayer Crop Science WoodlandCA 95695USA Averis Seeds B.V. 9640 AA Veendamthe Netherlands International Potato Center 1895 Avenida La MolinaLimaPeru USDA-ARS ProsserWA 99350USA Agriculture and Agri-Food Canada Fredericton Research and Development Centre FrederictonNB E3B 4Z7Canada School of Integrative Plant Science Cornell UniversityIthacaNY 14853-1901USA Department of Plant Sciences University of IdahoMoscowID 83844USA USDA-ARS Small Grains and Potato Germplasm ResearchAberdeenID 83210USA HZPC Research B.V. Edisonweg 58501 XG Jourethe Netherlands Department of Crop and Soil Science Oregon State UniversityHermistonOR 97838USA School of Biology and Ecology University of Maine5735 Hitchner Hall OronoME 04469USA Department of Horticultural Sciences Texas A&M UniversityCollege StationTX 77843-2133USA Department of Horticulture Oregon State UniversityCorvallisOR 97331USA Department of Horticultural Science North Carolina State UniversityRaleighNC 27695-7609USA Department of Horticulture University of Wisconsin-MadisonMadisonWI 53706USA Department of Horticulture Michigan State UniversityEast LansingMI 48824USA Institute for Biological Data Science Heinrich Heine UniversityDusseldorf40225 DusseldorfGermany Plant Resilience Institute Michigan State UniversityEast LansingMI 48824USA Present address:GenNovation B.V. Wageningenthe Netherlands

Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous *** assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous *** species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding *** a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid *** a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic *** StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent *** of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids.

关键词： potato allele diversity phased assembly polyploid pan-genome wild introgressions

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医疗病历数字化之路为何这样难？

商业周刊（中文版） 2012年第13期 68-71页

作者： Devin Leonard john Tozzi

去年年底的一天，一位老先生被心急如焚的家人送到凯萨医疗机构（kaiser Permanente）位于加州圣塔克拉拉的医疗中心看专科医生。一进诊室大门，老先生就开始不由自主地浑身抽搐起来。

关键词：医疗机构数字化病历克拉拉