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中国金融家 2005年第7期 60-61页

作者： john f. nash The Laureate of.1994 Nobel Memorial Prize in Economic Science Jr.

Calcium-mediated paired pulse depression in juvenile rat dorsal striatum

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Neural Regeneration Research 2012年第10期7卷 772-777页

作者： Yuf.ng Xie Michael f. Jackson john f. MacDonald Robarts Research Institute University of Western Ontario London Ontario Canada Department of.Physiology and Pharmacology University of Western Ontario London Ontario Canada Department of.Anatomy and Cell Biology University of Westem Ontario London Ontario Canada

As the major division of.the basal ganglia, neostriatum f.rms mutual connections with multiple brain areas and is critically involved in motor control and learning/memory. Long-term synaptic plasticity has been widely studied in dif.erent species recently. However, there are rare reports about the short-term synaptic plasticity in neostratium. In the present study, using f.eld excitatory postsynaptic potentials recording, we reported one f.rm of.short-term synaptic plasticity that is paired pulse depression in juvenile rat dorsal striatum slices induced by stimuli of.the white matter. The f.eld excitatory postsynaptic potentials could be abolished by α-amino-3-hydroxy-5-methylizoxazole-4-propionic acid receptor antagonist, 6-cyano-7-nitroquinoxaline-2,3-dione, but not by gamma-aminobutyric acid type A receptor antagonist bicuculline or dopamine D1 receptor antagonist SKf.81297. The paired pulse depression in the corticostratial pathway was dif.erent f.om paired pulse f.cilitation in the hippocampal CA1 synapse. In addition, the paired pulse depression was not af.ected by bath application of.gamma-aminobutyric acid type A receptor antagonist or dopamine D1 receptor antagonist. However, low calcium and high magnesium could attenuate the paired pulse depression. These f.ndings suggest a more complicated plasticity f.rm in the dorsal striatum of.juvenile rats that is dif.erent f.om that in the hippocampus, which is related with extracellular calcium.

关键词： paired pulses depression dorsal striatum calcium juvenile rats

Design of.Poiseuille f.ow Controllers Using the Method of.Inequalities

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International Journal of.Automation and computing 2009年第1期6卷 14-21页

作者： john McKernan James f. Whidborne George Papadakis Department of.Mechanical Engineering King s College London Strand Department of.Aerospace Sciences Cranfield University

This paper investigates the use of.the method of.inequalities （MoI） to design output-f.edback compensators f.r the problem of.the control of.instabilities in a laminar plane Poiseuille f.ow. In common with many f.ows, the dynamics of.streamwise vortices in plane Poiseuille f.ow are very non-normal. Consequently, small perturbations grow rapidly with a large transient that may trigger nonlinearities and lead to turbulence even though such perturbations would, in a linear f.ow model, eventually decay. Such a system can be described as a conditionally linear system. The sensitivity is measured using the maximum transient energy growth, which is widely used in the f.uid dynamics community. The paper considers two approaches. In the f.rst approach, the MoI is used to design low-order proportional and proportional-integral （PI） controllers. In the second one, the MoI is combined with Mcf.rlane and Glover＇s H∞ loop-shaping design procedure in a mixed-optimization approach.

关键词： Transient energy growth transient behaviour f.ow control Poiseuille f.ow method of.inequalities (MoI) mixed opti-mization H∞-optimization.

Case of.early right ventricular pacing lead perf.ration and review of.the literature

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World Journal of.Clinical Cases 2014年第6期2卷 206-208页

作者： Gary nash john Mark Williams Rajasekhar Nekkanti Assad Movahed Department of.Cardiovascular Sciences East Carolina University Brody School of Medicine East Carolina Heart Institute

We report a case of.a 77-year-old patient with complete atrioventricular block. She underwent permanent pacemaker implantation complicated by right ventricular lead perf.ration. This was suspected on transthoracic echocardiogram and conf.rmed by chest computed tomography. The lead was repositioned in the cardiac electrophysiology lab f.llowed by an uneventf.l course thereaf.er.

关键词： Pacemaker Lead Perf.ration

Landscape of.the mind

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Landscape of the mind

Staging colorectal cancer with the TNM 7^(th):The presumption of.innocence when applying the M category

作者： Hof.ecker john f.

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World Journal of.Gastroenterology 2013年第8期19卷 1152-1157页

作者： Giacomo Puppa Graeme Poston Per Jess Guy f.nash Kenneth Coenegrachts Axel Stang Service de Pathologie Clinique Hpitaux Universitaires de Genève1211 GenevaSwitzerland Department of.Surgery Aintree University HospitalsLiverpool L9 7ALUnited Kingdom Department of.Surgery Roskilde HospitalUniversity of Copenhagen2200 CopenhagenDenmark Department of.Colorectal Surgery Poole General HospitalPoole BH15 2JBUnited Kingdom Department of.Radiology AZ St.-Jan Brugge-Oostende AVB-8000 BrugesBelgium Department of.Oncology Hematology and Palliative CareAsklepios Hospital Hamburg-Barmbek22291 HamburgGermany

One of.the main changes of.the current TNM-7 is the elimination of.the category MX,since it has been a source of.ambiguity and misinterpretation,especially by *** the ultimate staging would be better perf.rmed by the patient's clinician who can classif. the disease M0(no distant metastasis) or M1(presence of.distant metastasis),having access to the completeness of.data resulting f.om clinical examination,imaging workup and pathology *** this important change doesn't take into account the diagnostic value and the challenge of.small indeterminate visceral lesions encountered,in particular,during radiological staging of.patients with colorectal *** this article the diagnosis of.these lesions with multiple imaging modalities,their f.equency,signif.cance and relevance to staging and disease management are described in a multidisciplinary *** particular the interplay between clinical,radiological and pathological staging,which are usually conducted independently,is *** integrated approach shows that there are both advantages and disadvantages to abandoning the MX *** avoid ambiguity arising both by applying and interpreting MX category f.r stage assigning,its abandoning seems *** recognition of.the importance of.small lesion characterization raises the need f.r applying a separate category;theref.re a proposal f.r their categorization is put *** using the proposed categorization the lack of.consideration f.r indeterminate visceral lesions with the current staging system will be overcome,also optimizing tailored f.llow-up.

关键词： Colorectal cancer Staging Indeterminate lesions Imaging Metastases

Meeting the Challenges of.Taxing Multinational Enterprises in New Zealand

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Belt and Road Initiative Tax Journal 2021年第2期2卷 59-63页

作者： john nash International Revenue Strategy New Zealand Inland Revenue

There have been signif.cant concerns globally regarding the undertaxation of.multinational enterprises(MNEs).New Zealand has considerably relied on MNEs in terms of.income tax *** a f.ll range of.measures to combat base erosion and prof.t shif.ing(BEPS)by MNEs have been implemented,guided by the products emanating f.om the OECD’s BEPS Action *** law changes have been buttressed by the New Zealand tax administration through undertaking a robust intelligence-led tax compliance programme targeting high risk sectors and issues involving *** there have been some trade-of.s in taking this approach,but New Zealand regards the desired behavioural shif.s by MNEs as a direct result of.this substantial work on BEPS,with little material impact on the level of.f.reign direct investment.

关键词： MNEs BEPS Compliance f.reign investment

Enhancing Tax Administration Capacity Building in Developing Countries: A New Zealand Perspective

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Belt and Road Initiative Tax Journal 2022年第1期3卷 25-29页

作者： john nash New Zealand Inland Revenue

f.r developing countries,raising revenues and protecting their tax bases are more important than ever in recovering f.om the *** a small developed country,New Zealand endeavours to provide capacity building assistance to developing regions,especially the Pacif.c *** provided encompasses the development of.core taxation systems as well as international tax matters such as the establishment of.exchange of.inf.rmation programmes and the implementation of.international tax *** in partnership with international and regional organisations has proved benef.cial,as demonstrated in the Pacif.c Initiative delivered over the last two ***-ef.ective and well-organised virtual delivery of.training courses has f.nctioned particularly well during the pandemic and will continue to f.ature prominently in f.ture assistance work.

关键词： Capacity building Tax administration Developing countries Assistance Ef.icient targeted partnership

Synchronous f.rmation of.the‘f.rearc’Bay of.Islands ophiolite and its basal high-temperature metamorphic sole constrained by U-Pb zircon ages

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Geoscience f.ontiers 2023年第6期14卷 234-272页

作者： Weiyao Yan john f.Casey Department of.Earth and Atmospheric Sciences University of HoustonHoustonTXUSA

The welded metamorphic sole at the base of.the Bay of.Islands Ophiolite Complex(BOIC)in the Northern Appalachians of.Newf.undland shows a typical inverted pressure-temperature(P-T)metamorphic gradient f.om HT-MP granulite to LT-LP greenschist *** incorporates maf.c volcanic/plutonic protoliths mixed with pelagic,hemi-pelagic and coarser epiclastic sedimentary *** LA-ICP-MS U–Pb concordia ages,trace elements,and Ti-in-zircon geothermometry f.r -250 zircon analyses f.om three metabasites of.the upper HT sole amphibolites with N-MORB-like protoliths are *** samples collected within meters of.the ophiolite peridotite-sole contact of.the Blow Me Down Mountain and North Arm Mountain massif. yielded the oldest comparable concordia ages of.487.7±2.6 Ma and 489.1±3.1 Ma,respectively,that are both within error of.the igneous age of.488.3±1.5 Ma of.the directly overlying BOIC ophiolite,which f.rmed at a supra-subduction zone(SSZ)f.rearc spreading center.A third slightly younger age of.484.2±2.4 Ma was obtained f.r an upper HT amphibolite sample with similar phase assemblages but collected30 m below the peridotite contact of.the Table Mountain *** crystals analyzed have similar size and morphologies,subparallel rare earth element(REE)variation patterns,and steep heavy REE-enrichments((Lu/Gd)_(cn)>20),signif.cant positive Ce anomalies(dominantly>5)and slight positive to dominantly negative Eu anomalies(1.2–0.4).Zircon shows Th/U mean values of.0.37–0.48 with little to no rim to core *** Ti-in-zircon mean crystallization temperatures range f.om764–787℃.These neocrystallized zircon crystals appear to be derived f.om thin leucosomes within the three *** other samples also f.om the upper HT sole show evidence of.inherited detrital zircon with core dates spanning the Cambrian Notre Dame Arc through older Laurentian-like basement and rif. age *** of.the sole took place below a hot f.rearc asthenospheric wed

关键词： Ophiolite metamorphic sole U-Pb zircon ages Hot subduction interf.ce Supra-subduction f.rearc spreading center Arc-continent collision Taconic Orogeny

Xylose: absorption, f.rmentation, and post-absorptive metabolism in the pig

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Journal of.Animal Science and Biotechnology 2018年第1期9卷 1-9页

作者： Nichole f.Huntley john f.Patience Department of.Animal Science 213 Kildee HallIowa State University Department of.Animal Science 201B Kildee HallIowa State University

Xylose, as β-1,4-linked xylan, makes up much of.the hemicel ulose in cel wal s of.cereal carbohydrates f.d to pigs. As inclusion of.f.brous ingredients in swine diets continues to increase, supplementation of.carbohydrases, such as xylanase,is of.interest. However, much progress is warranted to achieve consistent enzyme ef.icacy, including an improved understanding of.the utilization and energetic contribution of.xylanase hydrolysis product（i.e. xylooligosaccharides or monomeric xylose）. This review examines reports on xylose absorption and metabolism in the pig and identif.es gaps in this knowledge that are essential to understanding the value of.carbohydrase hydrolysis products in the nutrition of.the pig. Xylose research in pigs was f.rst reported in 1954, with only sporadic contributions since. Theref.re, this review also discusses relevant xylose research in other monogastric species, including humans. In both pigs and poultry, increasing purif.ed D-xylose inclusion general y results in linear decreases in perf.rmance, ef.iciency, and diet digestibility. However,supplementation levels studied thus f.r have ranged f.om 5% to 40%, while theoretical xylose release due to xylanase supplementation would be less than 4%. More than 95% of.ingested D-xylose disappears bef.re the terminal ileum but mechanisms of.absorption have yet to be f.l y elucidated. Some data support the hypothesis that mechanisms exist to handle low xylose concentrations but become overwhelmed as luminal concentrations increase. Very little is known about xylose metabolic utilization in vertebrates but it is wel recognized that a large proportion of.dietary xylose appears in the urine and signif.cantly decreases the metabolizable energy available f.om the diet. Nevertheless, evidence of.labeled D-xylose-1-^（14）C appearing as expired^（14）CO_2 in both humans and guinea pigs suggests that there is potential,although small, f.r xylose oxidation. It is yet to be determined if.pigs develop increased xy

关键词： Pentose utilization Swine Threitol Xylose absorption Xylose metabolism