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Asian Journal of Andrology 2019年第1期21卷 37-44页

作者： Cihan H Demirel Muammer Altok john W davis Department of Urology The University of Texas MD Anderson Cancer CenterHoustonTexas 77030USA.

In recent years,it has come a long way in the diagnosis,treatment,and follow-up of prostate *** this,it was argued that definitive treatments could cause overtreatment,particularly in the very low,low,and favorable risk *** alternative treatment and follow-up methods are being considered for this group of patients,active surveillance is seen as a good alternative for patients with very low and low-risk groups in this ***,it has become necessary to find other alternatives for patients in the favorable risk group or patients who cannot adopt active *** the light of technological developments,the concept of focal therapy was introduced with the intensification of research to treat only the lesioned area instead of treating the entire organ for prostate lesions though there are not many publications about many of them *** to the initial results,it was understood that the results could be good if the appropriate focal therapy technique was applied to the appropriate ***,focal therapies have begun to find their"middle ground"place between definitive therapies and active follow-up.

关键词： focal therapy multiparametric magnetic resonance imaging prostate biopsy prostate cancer prostatic neoplasms

Comparison of aerosol optical depth of UV-B Monitoring and Research Program （UVMRP）, AERONET and MODIS over continental United States

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Frontiers of Earth Science 2013年第2期7卷 129-140页

作者： Hongzhao TANG Maosi CHEN john davis Wei GAO USDA UV-B Monitoring and Research Program Natural Resource Ecology Laboratory Colorado State University Fort Collins CO 80521 USA Department of Ecosystem Science and Sustainability Colorado State University Fort Collins C-O 80521 USA

The concern about the role of aerosols as to their effect in the Earth-Atmosphere system requires observation at multiple temporal and spatial scales. The Moderate Resolution Imaging Spectroradiameters （MODIS） is the main aerosol optical depth （AOD） monitoring satellite instrument, and its accuracy and uncertainty need to be validated against ground based measurements routinely. The comparison between two ground AOD measurement programs, the United States Department of Agriculture （USDA） Ultmviolet-B Monitoring and Research Program （UVMRP） and the Aerosol Robotic Network （AERONET） program, confirms the consistency between them. The intercomparison between the MODIS AOD, the AERONET AOD, and the UVMRP AOD suggests that the UVMRP AOD measurements are suited to be an alternative ground-based validation source for satellite AOD products. The experiments show that the spatial-temporal dependency between the MODIS AOD and the UVMRP AOD is positive in the sense that the MODIS AOD compare more favorably with the UVMRP AOD as the spatial and temporal intervals are increased. However, the analysis shows that the optimal spatial interval for all time windows is defined by an angular subtense of around 1° to 1.25°, while the optimal time window is around 423 to 483 minutes at most spatial intervals. The spatial-temporal approach around 1.25° ＆ 423 minutes shows better agreement than the prevalent strategy of 0.25° ＆ 60 minutes found in other similar investigations.

关键词： aerosol optical depth (AOD) United States Department of Agriculture (USDA) UV-B Monitoring andResearch Program (UVMRP) Aerosol Robotic Network (AERONET) Moderate Resolution Imaging Spectmradiameters (MODIS) validation spatial-temporal approach

The calibration methods for Multi-Filter Rotating Shadowband Radiometer： a review

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Frontiers of Earth Science 2013年第3期7卷 257-270页

作者： Maosi CHEN john davis Hongzhao TANG Carolyn OWNBY Wei GAO USDA UV-B Monitoring and Research Program Natural Resource Ecology Laboratory Colorado State University Fort Collins CO 80521 USA Department of Ecosystem Science and Sustainability Colorado State University Fort Collins CO 80521 USA

The continuous, over two-decade data record from the Multi-Filter Rotating Shadowband Radiometer （MFRSR） is ideal for climate research which requires timely and accurate information of important atmospheric components such as gases, aerosols, and clouds. Except for parameters derived from MFRSR measurement ratios, which are not impacted by calibration error, most applications require accurate calibration factor（s）, angular correction, and spectral response function（s） from calibration. Although a laboratory lamp （or reference） calibration can provide all the information needed to convert the instrument readings to actual radiation, in situ calibration methods are implemented routinely （daily） to fill the gaps between lamp calibrations. In this paper, the basic structure and the data collection and pretreatment of the MFRSR are described. The laboratory lamp calibration and its limita- tions are summarized. The cloud screening algorithms for MFRSR data are presented. The in situ calibration methods, the standard Langley method and its variants, the ratio-Langley method, the general method, Alexandrov＇s comprehensive method, and Chen＇s multi-channel method, are outlined. The reason that all these methods do not fit for all situations is that they assume some properties, such as aerosol optical depth （AOD）, total optical depth （TOD）, precipitable water vapor （PWV）, effective size of aerosol particles, or angstrom coefficient, are invariant over time. These properties are not universal and some of them rarely happen. In practice, daily calibration factors derived from these methods should be smoothed to restrain elTor.

关键词： Multi-Filter Rotating Shadowband Radiometer (MFRSR) calibration review

Electrical stimulation and denervated muscles after spinal cord injury

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Neural Regeneration Research 2020年第8期15卷 1397-1407页

作者： Subhalakshmi Chandrasekaran john davis Ines Bersch Gary Goldberg Ashraf S.Gorgey Spinal Cord Injury and Disorders Hunter Holmes McGuire VA Medical CenterRichmondVAUSA Swiss Paraplegic Centre NottwilSwitzerland Institute of Clinical Sciences Department of Orthopedics at the University of GothenburgGothenburgSweden Department of Physical Medicine and Rehabilitation Virginia Commonwealth UniversityRichmondVAUSA Electrodiagnostic Center Hunter Holmes McGuire VA Medical CenterRichmondVAUSA

Spinal cord injury(SCI)population with injury below T10 or injury to the cauda equina region is characterized by denervated muscles,extensive muscle atrophy,infiltration of intramuscular fat and formation of fibrous *** morphological changes may put individuals with SCI at higher risk for developing other diseases such as various cardiovascular diseases,diabetes,obesity and ***,there is no available rehabilitation intervention to rescue the muscles or restore muscle size in SCI individuals with lower motor neuron ***,hereby,performed a review of the available evidence that supports the use of electrical stimulation in restoration of denervated muscle following *** pulse width stimulation(LPWS)technique is an upcoming method of stimulating denervated *** primary objective is to explore the best stimulation paradigms(stimulation parameters,stimulation technique and stimulation wave)to achieve restoration of the denervated *** parameters,such as the pulse duration,need to be 100–1000 times longer than in innervated muscles to achieve desirable excitability and *** use of electrical stimulation in animal and human models induces muscle *** in animal models indicate that electrical stimulation,with a combination of exercise and pharmacological interventions,have proven to be effective in improving various aspects like relative muscle weight,muscle cross sectional area,number of myelinated regenerated fibers,and restoring some level of muscle *** studies have shown similar outcomes,identifying the use of LPWS as an effective strategy in increasing muscle cross sectional area,the size of muscle fibers,and improving muscle ***,displaying promise is an effective future stimulation *** summary,LPWS is a novel stimulation technique for denervated muscles in humans with *** studies on LPWS of denervated muscles will help in translating

关键词： denervation DXA electrical stimulation LMN injury LPWS MRI spinal cord injury stimulation parameters

Prostate cancer upgrading or downgrading of biopsy Gleason scores at radical prostatectomy:prediction of"regression to the mean"using routine clinical features with correlating biochemical relapse rates

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Asian Journal of Andrology 2019年第6期21卷 598-604页

作者： Muammer Altok Patricia Troncoso Mary F Achim Surena F Matin Graciela N Gonzalez john W davis Department of Urology University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Department of Pathology University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Department of Biostatistics University of Texas MD Anderson Cancer CenterHoustonTX 77030USA.

Recommendations for managing clinically localized prostate cancer are structured around clinical risk criteria,with prostate biopsy(PB)Gleason score(GS)being the most important *** to radical prostatectomy(RP)specimen upgrading/downgrading is welldescribed,and is often the ratio nale for costly imaging or genomic *** prese nt simple,no-cost an a lyses of clinical parametersto predict which GS 6 and GS 8 patients will change to GS 7 at *** May 2006 to December 2012,1590 patientsunderwent robot-assisted radical prostatectomy(RARP).After exclusions,we identified a GS 6 cohort of 374 patients and a GS 8cohort of 91 *** this era,>1000 additional patients were enrolled in an active surveillanee(AS)*** GS 6,265(70.9%)of 374 patients were upgraded,and the cohort included 183(48.9%)patients eligible for AS by the Prostate Cancer ResearchInternational Active Surveillance Study(PRIAS)standards,of which 57.9%were *** features that predicted a>90%chanceof upgrading included≥7 cores positive,maximum foci length≥8 mm in any core,and total tumor involvement≥30%.For GS 8,downgrading occurred in 46(50.5%),which was significantly higher for single core versus multiple cores(80.4%vs 19.6%,P=0.011).Biochemical recurre nee(BCR)occurred in 3.4%of GS 6 upgraded versus 0%non upgraded,and in GS 8,19.6%downgraded versus42.2%nondown *** coun seling men with clin ically localized prostate can cer,the odds of GS cha nge should be presented,andcertain men with high-volume GS 6 or low-volume GS 8 can be counseled with GS 7-based recommendations.

关键词： biopsy down grade Gleas on score prostate cancer upgrade

The International Prostate Forum introduction and history

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Asian Journal of Andrology 2015年第6期17卷 863-863,I0006页

作者： john W davis Tsuneharu Miki Atif Akdas Hiroki Watanabe Ziya Kirkali Run Wang R Joseph Babaian Department of Urology The University of Texas MDAnderson Cancer Center Houston Texas 77030 USA Department of Urology Kyoto Prefectural University ofMedicine Kyoto Japan Department of Urology Schoolof Medicine Marmara University Istanbul Turkey Watanabe Memorial Choumei Research Laboratory Shiga Japan Dokuz EylOI University School ofMedicine Department of Urology Izmir Turkey Division of Urology University of Texas Medical Schoolat Houston Department of Urology Houston TexasUSA Department of Urology University of Texas MDAnderson Cancer Center Houston Texas 77030 USA

The International Prostate Forum （IPF） originally started with three urology departments in Japan, Turkey, and the United States. The forum emphasized discussions and presentations of new knowledge in all areas of prostate diseases with an early emphasis on ultrasound and diagnostics. The meeting has generally run every 2 years and rotated through the three sites with new leadersjoining the effort. Over the years, the meeting has enjoyed a diverse locale and points of emphasis. The latter agendas now cover all aspects of the benign prostate disease, prostate cancer screening, prostate cancer diagnosis and staging, and therapies. Table 1 summarizes the dates of the meetings, locations, and chairman.

关键词： International Prostate history

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What & IF

明日风尚 2013年第3期 122-133页

作者：晓琦 john davis Ron Arad工作室

有人说Ron Arad是一个神话,众多媒体给他冠上设计之父的称谓。他的家具、雕塑品是当代艺术市场最受瞩目的作品;在设计专业学生眼中,他是一个英雄,人人都想成为Ron Arad。Ron Arad 1951年出生在以色列的特拉维夫(Tel Aviv),他的父母都是... 详细信息

有人说Ron Arad是一个神话,众多媒体给他冠上设计之父的称谓。他的家具、雕塑品是当代艺术市场最受瞩目的作品;在设计专业学生眼中,他是一个英雄,人人都想成为Ron Arad。Ron Arad 1951年出生在以色列的特拉维夫(Tel Aviv),他的父母都是艺术家,良好的家庭氛围给了他先天的艺术滋养。1973年,他完成了在耶路撒冷Bezalel艺术设计学院的学业之后来到了伦敦,在众星云集的伦敦建筑联盟学院AA(Architectural Association)师从英国建筑师彼得·库克(Peter Cook)和瑞士建筑大师伯纳德·屈米(Bernard Tschumi),和如今叱咤建筑界的扎哈·哈迪德(Zaha Hadid)是同班同学。Ron Arad毕业于1979年,此后在一家建筑事务所短暂的打工经历坚定了Arad创建属于自己设计公司的信心。1981年,他与朋友合伙成立了名为‘One Off’的设计公司,1989年,他们在北伦敦的Chalk Farm重新成立了以Ron Arad名字命名的Ron Arad及合伙人设计事务所。与此同时。

关键词：设计工作室 IF What 哈迪德扎哈第一感薄钢板塑料应用产品设计领域伯纳德

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打造跨越国界的品牌

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Long-term effect of intrathecal baclofen treatment on bone health and body composition after spinal cord injury:A case matched report

2012年

主讲人： john davis

来源：爱迪科森网上报告厅评论

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World Journal of Orthopedics 2020年第10期11卷 453-464页

作者： Dora E Ifon Mina P Ghatas john C davis Refka E Khalil Robert A Adler Ashraf S Gorgey Spinal Cord Injury and Disorders Center Central Virginia VA Health Care SystemRichmondVA 23249United States Medical Service Central Virginia VA Health Care SystemRichmondVA 23249United States Department of Internal Medicine Division of EndocrinologyDiabetes and MetabolismVirginia Commonwealth UniversityRichmondVA 23298United States Department of Physical Medicine and Rehabilitation Virginia Commonwealth UniversityRichmondVA 23298United States

BACKGROUND Severe spasticity may negatively impact functionality and quality of life after spinal cord injury(SCI).Intrathecal baclofen treatment(IBT)is effectively used to manage severe spasticity and reduce ***,long-term IBT may have a negative effect on bone mineral content(BMC),bone mineral density(BMD)and body composition(such as percentage fat mass and lean body mass).We demonstrated the negative effects of long-term IBT use in a single case compared with two non-IBT *** SUMMARY A 46-year old Caucasian male Veteran(case)with a 21 year history of complete tetraplegia(complete C6 SCI)was implanted with IBT for 20 *** case was matched to two participants with different time since injuries[2(match 1)and 13(match 2)years]without *** BMC and BMD at the epiphysis and metaphysis of the distal femur and proximal tibia were evaluated using dual knee and the dual femur modules of GE Lunar iDXA *** and leg body composition assessments were also conducted for the three *** effect of long-term IBT was demonstrated by changes in BMD,consistent with bone demineralization,at the distal femur and proximal tibia and changes in percentage fat mass and lean mass of *** case showed 113%lower BMD at the distal femur,and 78.1%lower at the proximal tibia compared to match 1,moreover the case showed 45%lower BMD at the distal femur,and no observed changes at the proximal tibia compared to match *** case had 27.1%and 16.5%greater leg%fat mass compared to match 1 and match 2,***,the case had 17.4%and 11.8%lower%leg lean mass compared to match 1 and match 2,*** Long-term IBT may impact bone health and body composition parameters in persons with complete *** may be prudent to encourage regular screening of individuals on long-term IBT considering the prevalence of osteoporosis related fractures,cardiovascular diseases,and metabolic disorders in this population.

关键词： Intrathecal baclofen Spasticity Bone mineral density Epiphysis Metaphysis Spinal cord injury Case report

Cerebral venous sinus thrombosis:changing trends in the incidence,age and gender(findings from the CMC Vellore CVT registry)

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Stroke & Vascular Neurology 2024年第3期9卷 252-257页

作者： Angel Miraclin T john davis Prasad George Abraham Ninan Mahasampath Gowri Deepti Bal Atif Iqbal Ahmed Shaikh Rohit N Benjamin Appaswamy Thirumal Prabhakar Ajith Sivadasan Vivek Mathew Sanjith Aaron Department of Neurological Sciences Christian Medical CollegeVelloreTamil NaduIndia Department of Biostatistics Christian Medical CollegeVelloreTamil NaduIndia

Background Multiple cerebral venous sinus thrombosis(CVT)registries from various geographical regions indicate that female gender,the use of contraceptive pills,pregnancy and puerperium are important risk *** this study,we report the changes in the epidemiology of patients with CVT managed over the past 26 *** The CMC Vellore CVT registry is a prospectively maintained database at the Christian Medical College,Vellore since January *** software was used to analyse the data and assess the changes in the incidence,age and gender distribution over the previous 26 *** Among 1701 patients treated during the study period,908(53%)were women and 793(47%)were *** mean incidence of CVT was 49 per 100000 admissions before 2010,which increased to 96 per 100000 after *** gender had a higher odds of developing CVT OR–2.07(CI 1.68 to 2.55,p<0.001).This could be attributed to the declining incidence of postpartum CVT after 2010 compared with the decade before 2010(50%vs 20%).The mean age at presentation had increased from 24.5 to 33.2 years in the last *** There was a clear change in the gender pattern from being a condition with female preponderance,to one where equal or more men are being *** incidence of postpartum CVT cases could be the driving *** increase in the overall incidence of CVT cases was noted,probably due to a higher index of clinical suspicion and better diagnostic imaging modalities.

关键词： CVT driving maintained