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Biomedical and Environmental Sciences 2024年第4期37卷 428-431页

作者： VICTOR Abiola Adepoju OKECHUKWU Innocent Onyezue SAFAYET Jamil OLALEKAN john Okesanya DON Eliseo Lucero-Prisno Ⅲ Department of HIV and Infectious Diseases Jhpiegoan affiliate of John Hopkins UniversityAbujaNigeria Department of Prevention and Community Directorate APIN Public Health InitiativesAbujaNigeria Department of Public Health Daffodil International UniversityDhaka-1216Bangladesh Department of Public Health and Maritime Transport University of ThessalyVolosGreece Department of Global Health and Development London School of Hygiene and Tropical MedicineLondonUnited Kingdom

In the ever-evolving landscape of Alzheimer’s treatment,lecanemab(Leqembi)has emerged as a promising *** conventional therapies that merely alleviate symptoms,lecanemab is a humanized monoclonal antibody with a distinct *** targets protofibrils,insoluble fibrils,amyloid oligomers,and soluble amyloid-beta protofibrils,which are known to be especially damaging to neurons,with high accuracy.

关键词： Alzheimer amyloid Therapeutic

Misty Mood of Chinese Shoegaze

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城市漫步（GBA版） 2024年第5期 12-17页

作者： Kirby john Carney 不详

Music likeshoegaze can easily hypnotize youwith itsdreamlike,*** atmospheric indie rock subgenrefirst emerged in the UK in the late1980s,pioneered bybands such as My Bloody Valentine and *** has unexpectedly embraced shoegaze in recent *** chilled seasidevibes of Xiamen tothe urban pulse of Shanghai,an underground community of Chinese shoegazers has been steadily crafting their own wistful,immersive sound.

关键词： Xiamen indie underground

Kuafu as Buri:Bridging Ancient Worlds——A Study of Transcultural Confucianism Through Mythological Narratives

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走进孔子（中英文） 2024年第4期 111-128页

作者： john Qiong WANG School of Foreign Studies at Guangxi Minzu University

*** This article delves into the profound impact of Confucianism on the cultural,historical,and philosophical landscape of Chinese society,highlighting its role beyond the realms of governance and education to influence literary,historical,and mythological *** argues that Confucianism has been instrumental in shaping the literary and mythological landscapes,engaging in what is termed“Confucianisation,”a process that intertwines moral philosophy with cultural narratives,including myths(Yao 2000;Zhang 2015;Li 2010;Wang 2017).

关键词： landscape education ism

A Warm Reception for the Year of the Dragon

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国际人才交流 2024年第3期 61-62页

作者： Michael john Harrold Documentary Dept CGTN

A dragon year,so I read somewhere,is one in which,individually and collectively,we are filled with energy and ***’s supposed to be a year of transformation,good fortune and prosperity;all of which,it seems to me,is j... 详细信息

关键词： collective filled dragon

Another SSOR Iteration Method

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American Journal of Computational Mathematics 2024年第2期14卷 248-256页

作者： Thomas Smotzer john Buoni Department of Mathematics and Statistics Youngstown State University Youngstown Ohio USA

Kellogg gave a version of the Peaceman-Radford method. In this paper, we introduce a SSOR iteration method which uses Kellogg’s method. The new algorithm has some advantages over the traditional SSOR algorithm. A Cyc... 详细信息

关键词： Matrix Splitting SSOR Iteration KSSOR Iteration Method Kellogg-Type SSOR Iteration Cyclic Reduction

The Quantum Microverse: A Prime Number Framework for Understanding the Universe

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American Journal of Computational Mathematics 2024年第2期14卷 264-274页

作者： john R. Crary Independent Researcher Lake Zurich IL USA

This study aims to demonstrate a proof of concept for a novel theory of the universe based on the Fine Structure Constant (α), derived from n-dimensional prime number property sets, specifically α = 137 and α = 139. The FSC Model introduces a new perspective on the fundamental nature of our universe, showing that α = 137.036 can be calculated from these prime property sets. The Fine Structure Constant, a cornerstone in Quantum Electrodynamics (QED) and Quantum Chromodynamics (QCD), implies an underlying structure. This study identifies this mathematical framework and demonstrates how the FSC model theory aligns with our current understanding of physics and cosmology. The results unveil a hierarchy of α values for twin prime pairs U{3/2} through U{199/197}. These values, represented by their fraction parts α♊ (e.g., 0.036), define the relative electromagnetic forces driving quantum energy systems. The lower twin prime pairs, such as U{3/2}, exhibit higher EM forces that decrease as the twin pairs increase, turning dark when they drop below the α♊ for light. The results provide classical definitions for Baryonic Matter/Energy, Dark Matter, Dark Energy, and Antimatter but mostly illustrate how the combined α♊ values for three adjacent twin primes, U{7/5/3/2} mirrors the strong nuclear force of gluons holding quarks together.

关键词： Fine Structure Constant Fractional Coupling Constants Matter/Antimatter Dark Matter/Energy Quantum Gravity Prime Numbers Set Theory

Adjustments for Kurtosis and Continuity on the Prentice Test

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Advances in Pure Mathematics 2024年第2期14卷 101-117页

作者： Lily Gebhart john Kolassa Math Department Occidental College Los Angeles USA Department of Statistics University of New Jersey Piscataway USA

The test of Prentice [1] is a non-parametric statistical test for the two-way analysis of variance using ranks. The null distribution of this test typically is approximated using the Chi-square distribution. However, the exact null distribution deviates from the Chi-square approximation in certain cases commonly found in applications of the test, motivating adjustments to the distribution. This manuscript presents adjustments to this null distribution correcting for continuity, multivariate skewness, and multivariate kurtosis. The effects of alternative scoring methods as non-polynomial functions of rank sums are also presented as a broader application of the approximation.

关键词： Friedman Test Prentice Test Edgeworth Approximation

Proof of Concept for a Twin Prime Number Universe Using Set Theory

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American Journal of Computational Mathematics 2024年第3期14卷 305-317页

作者： john R. Crary Independent Researcher Lake Zurich IL USA

The Fine Structure Constant (eFSC) Model attempts to give a classical definition to a magical number that underlies much of quantum physics. The Fine Structure Constant (α) value equal to 137.03599206 represents a dimensionless constant that characterizes the strength of the electromagnetic (EM) interaction between subatomic charged particles. Python-generated property counts for the twin prime force F{139/137} show that the adjusted ratio gives a value of α = 137.036. This implies a mathematical framework underlying this constant is based on twin prime numbers and set theory. This study attempts to demonstrate a proof of concept that a hierarchy of fractional twin prime (αII) forces replicates the quantum nature of the universe and is aligned with the Standard Model of Particle Physics. An expanded eFSC Model demonstrates that twin prime forces and their property sets are mathematically viable substitutes for nuclear reactions, as demonstrated for the Beta-minus decay of neutrons into protons. Most significantly, the positive and negative prime numbers define these nuclear reactants and products as positive or negatively charged ions. Furthermore, the eFSC Model provides new insights regarding the hierarchy of EM forces underlying the quantum nature of the universe.

关键词： Fine Structure Constant (α) Prime Numbers Set Theory Conceptual Model Quantum Physics Light and Matter Beta-Minus Decay

Brain Research on Mental Disorders: A Criticism

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Open Journal of Medical Psychology 2024年第3期13卷 71-85页

作者： john R. Rossiter Faculty of Business and Law University of Wollongong Wollongong Australia School of Psychology Charles Sturt University Wagga Wagga Australia

Objective: To expose the problems and inherent limitations of neuroscience-based brain research on mental disorders. Method: Discussion of the theory underlying brain research on mental disorders, followed by a systematic evaluation of typical studies. Results: The fundamental problem is that brain researchers fail to differentiate between biological mental disorders in which brain processes cause the disorder (notably schizophrenia, bipolar disorder, and melancholic depression) and learned mental disorders in which brain processes mediate but do not cause the disorder (which is the case with reactive depression, reactive anxiety, OCD, and PTSD). Researchers have been unsuccessful in identifying mechanisms in the brain that cause biological mental disorders, and will never be able to locate the innumerable specific neural connections that mediate learned mental disorders. Moreover, the author’s review of typical studies in this field shows that they have serious problems with theory, measurement, and data analysis, and that their findings cannot be trusted. Conclusions: Neuroscience-based brain research on mental disorders, unlike other neurological research, has been an expensive failure and it is not worth continuing.

关键词： Neuroscience-Based Brain Research Biological Mental Disorders Learned Mental Disorders Research Problems

PagMYB128 regulates secondary cell wall formation by direct activation of cell wall biosynthetic genes during wood formation in poplar

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Journal of Integrative Plant Biology 2024年第8期66卷 1658-1674页

作者： Yuanyuan Hao Fachuang Lu Seung-Won Pyo Min-Ha Kim Jae-Heung Ko Xiaojing Yan john Ralph Quanzi Li State Key Laboratory of Tree Genetics and Breeding Chinese Academy of ForestryBeijing 100091China Department of Biochemistry and DOE Great Lakes Bioenergy Research Center Wisconsin Energy InstituteUniversity of Wisconsin-MadisonWisconsin 53726USA Department of Plant&Environmental New Resources Kyung Hee UniversityYongin 17104Korea

The biosynthesis of cellulose,lignin,and hemicelluloses in plant secondary cell walls(SCWs)is regulated by a hierarchical transcriptional regulatory *** network features orthologous transcription factors shared between poplar and Arabidopsis,highlighting a foundational similarity in their genetic ***,knowledge on the discrepant behavior of the transcriptional-level molecular regulatory mechanisms between poplar and Arabidopsis remains *** this study,we investigated the function of PagMYB128 during wood formation and found it had broader impacts on SCW formation compared to its Arabidopsis ortholog,*** poplar trees overexpressing PagMYB128 exhibited significantly enhanced xylem development,with fiber cells and vessels displaying thicker walls,and an increase in the levels of cellulose,lignin,and hemicelluloses in the *** contrast,plants with dominant repression of PagMYB128 demonstrated the opposite *** sequencing and reverse transcription–quantitative polymerase chain reaction showed that PagMYB128 could activate SCW biosynthetic gene expression,and chromatin immunoprecipitation along with yeast one-hybrid,and effector–reporter assays showed this regulation was *** analysis revealed that PagSND1(SECONDARY WALL-ASSOCIATED NAC-DOMAIN PROTEIN1)directly regulates PagMYB128 but not cell wall metabolic genes,highlighting the pivotal role of PagMYB128 in the SND1-driven regulatory network for wood development,thereby creating a feedforward loop in SCW biosynthesis.

关键词： cellulose hemicellulose lignin PagMYB128 Populus transcription factor wood formation