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The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Frontiers of Medicine 2023年第3期17卷 527-533页

作者： Kevin M.Veen Grigorios Papageorgiou Casper F.Zijderhand Mostafa M.Mokhles jasper j.Brugts Olivier C.Manintveld Alina A.Constantinescu jos A.Bekkers johanna j.makkenberg Ad j.j.CBogers Kadir Caliskan Department of Cardiothoracic Surgery Erasmus MC3000 CA RotterdamThe Netherlands Department of Biostatistics Erasmus MC3000 CA RotterdamThe Netherlands Department of Cardiology Erasmus MC3000 CA RotterdamThe Netherlands

In this study,we aim to elucidate the clinical impact and long-term course of tricuspid regurgitation(TR),taking into account its dynamic nature,after biatrial orthotopic heart transplant(OHT).All consecutive adult patients undergoing biatrial OHT(1984−2017)with an available follow-up echocardiogram were ***-models were used to model the evolution of *** mixed-model was inserted into a Cox model in order to address the association of the dynamic TR with *** total,572 patients were included(median age:50 years,males:74.9%).Approximately 32% of patients had moderate-to-severe TR immediately after ***,this declined to 11%on 5 years and 9% on 10 years after surgery,adjusted for survival *** mechanical support was associated with less TR during follow-up,whereas concurrent LV dysfunction was significantly associated with more TR during *** at 1,5,10,20 years was 97%±1%,88%±1%,66%±2% and 23%±2%,*** presence of moderate-to-severe TR during follow-up was associated with higher mortality(HR:1.07,95%CI(1.02–1.12),p=0.006).The course of TR was positively correlated with the course of creatinine(R=0.45).TR during follow-up is significantly associated with higher mortality and worse renal ***,probability of TR is the highest immediately after OHT and decreases ***,it may be reasonable to refrain from surgical intervention for TR during earlier phase after OHT.

关键词： orthotopic heart transplant tricuspid regurgitation clinical impact biatrial heart transplantation

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Estimation of drag forces caused by natural woody vegetation of different scales

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journal of Hydrodynamics 2014年第4期26卷 608-623页

作者： jALONEN johanna jRVEL juha Department of Civil and Environmental Engineering Aalto University

To reliably estimate water levels and velocities in vegetated rivers and floodplains, flow resistance models based on physical plant properties are advantageous. The purpose of this study is （1） to assess the suitable parameterization of woody riparian vegetation in estimating the drag forces, （2） to address the effect of plant scale on the drag estimates and reconfiguration, and （3） to evaluate the applicability of three recently developed flow resistance models. Experiments on four tree species in a towing tank together with detailed characterization of tree properties were carried out to establish a novel dataset. Despite the variability in the tree height （0.9 m-3.4 m）, the stem, leaf and total areas proved to be suitable characteristic dimensions for estimating the flow resistance at different scales. Evaluations with independent data revealed that the tested models produced reasonable results. The performance of the models was controlled by the parameter values used rather than the model structure or the plant scale.

关键词： drag force flow resistance woody vegetation modelling

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Cultivating more-than-human care: Exploring bird watching as a landscaping practice on the example of sand martins and flooded gravel pits

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Frontiers of Architectural Research 2022年第6期11卷 1205-1213页

作者： johanna just Institute for Landscape and Urban Studies Prof.Teresa Galí-IzardChair of Being AliveDepartment of ArchitectureETH ZürichCH-8093 ZürichSwitzerland

The environmental crisis has created a demand for practices that build awareness about the interconnections of diverse forms of life,allowing humans to understand complex earthly relationships and reconnect with the land they *** paper contributes to this debate by investigating bird watching activities and their relevance for architects and landscape *** upon multispecies studies and the notion of landscape thinking,it examines the potential of birding as a caring landscaping *** analyzes the relationship between birders and sand martins in two case studies and probes how birders develop attentiveness for the birds and their shared *** investigation suggests that birding fosters care beyond the observed *** can trigger a landscaping practice comparable to landscape thinking that helps humans reconnect with the land,fostering response-able spatial design practices.

关键词： More-than-human Care Birding Landscaping Sand martin Gravel extraction

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Finding stable multi-component materials by combining cluster expansion and crystal structure predictions

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npj Computational Materials 2023年第1期9卷 2137-2146页

作者： Adam Carlsson johanna Rosen Martin Dahlqvist Materials Design Department of PhysicsChemistryand Biology(IFM)Linköping UniversitySE-58183 LinköpingSweden

A desired prerequisite when performing a quantum mechanical calculation is to have an initial idea of the atomic positions within an approximate crystal *** atomic positions combined should result in a system located in,or close to,an energy ***,designing low-energy structures may be a challenging task when prior knowledge is scarce,specifically for large multi-component systems where the degrees of freedom are close to *** this paper,we propose a method for identification of low-energy crystal structures within multi-component systems by combining cluster expansion and crystal structure predictions with density-functional theory *** structure prediction searches are applied to the Mo_(2)AlB_(2) and Sc2AlB_(2) ternary systems to identify candidate structures,which are subsequently used to explore the quaternary(pseudo-binary)(Mo_(x)Sc_(1–x))2AlB_(2) system through the cluster expansion formalism utilizing the ground-state search ***,we show that utilizing low-energy structures found within the cluster expansion ground-state search as seed structures within crystal structure predictions of(Mo_(x)Sc_(1–x))2AlB_(2) can significantly reduce the computational *** this combined approach,we not only correctly identified the recently discovered Mo_(4/3)Sc_(2/3)AlB_(2) i-MAB phase,comprised of in-plane chemical ordering of Mo and Sc and with Al in a Kagomélattice,but also predict additional low-energy structures at various *** result demonstrates that combining crystal structure prediction with cluster expansion provides a path for identifying low-energy crystal structures in multi-component systems by employing the strengths from both frameworks.

关键词： structure cluster crystal

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What Do We Really Know about Cellulose Biosynthesis in Higher Plants?

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journal of Integrative Plant Biology 2010年第2期52卷 161-175页

作者： Gea Guerriero johanna Fugelstad Vincent Bulone Division of Glycoscience School of BiotechnologyRoyal Institute of TechnologyAlbaNova University CenterSE-106 91 StockholmSweden

Cellulose biosynthesis is one of the most important biochemical processes in plant biology. Despite the considerable progress made during the last decade, numerous fundamental questions related to this key process in plant development are outstanding. Numerous models have been proposed through the years to explain the detailed molecular events of cellulose biosynthesis. Almost all models integrate solid experimental data with hypotheses on several of the steps involved in the process. Speculative models are most useful to stimulate further research investigations and bring new exciting ideas to the field. However, it is important to keep their hypothetical nature in mind and be aware of the risk that some undemonstrated hypotheses may progressively become admitted. In this review, we discuss the different steps required for cellulose formation and crystallization, and highlight the most important specific aspects that are supported by solid experimental data.

关键词： cell What Do We Really Know about Cellulose Biosynthesis in Higher Plants

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Improved Responses with Multitaper Spectral Analysis for Magnetotelluric Time Series Data Processing:Examples from Field Data

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Acta Geologica Sinica(English Edition) 2024年第S01期98卷 14-17页

作者： Matthew j.COMEAU Rafael RIGAUD johanna PLETT Michael BECKEN Alexey KUVSHINOV Department of Geoscience&Engineering Delft University of Technology The Netherlands Institute of Geophysics ETHZürichSwitzerland Institut für Geophysik Universität MünsterGermany

In order to attain good quality transfer function estimates from magnetotelluric field data(i.e.,smooth behavior and small uncertainties across all frequencies),we compare time series data processing with and without a multitaper approach for spectral *** are several common ways to increase the reliability of the Fourier spectral estimation from experimental(noisy)data;for example to subdivide the experimental time series into segments,taper these segments(using single taper),perform the Fourier transform of the individual segments,and average the resulting spectra.

关键词： magnetotellurics electrical resistivity time series processing Fourier analysis multitaper

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Firm Size and Work Compensation in China

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China & World Economy 2014年第1期22卷 67-82页

作者： johanna Rickne School of International and Public Affairs Columbia Universityand Research Institute for Industrial EconomicsIFN

Remarkably, recent research on the Chinese labor market has suggested that the situation in China is inconsistent with the stylized fact that large firms pay higher wages and offer more generous benefits. Expanding the empirical basis from 78 to 300 000 industrial firms, I overturn theprevious result andshow that wage determination in the averagefirmfits the international norm. Exploring subsamples of firms I also point to a likely source for the conflictingfindings： firm size is positively correlatedwith the average wage in private firms, but negatively correlated with the average wage in the state-owned sector. These novel results couM guide future studies aiming to understand the sources of the firm size wage premium, and, in particular, studies that target the largest industrial labor market in the world

关键词： China earnings firm size work compensation

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Lock Foot Syndrome

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上海针灸杂志 2000年第S1期19卷 85-87页

作者： johanna Brand M.D.ofjBQl-Gong International A/S Owner of Qigong A/S Research

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Dietary zinc and metallothionein on small intestinal disaccharidases activity in mice

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World journal of Gastroenterology 2011年第3期17卷 354-360页

作者： Cuong D Tran johanna Cool Cory j Xian Gastroenterology Unit ChildrenYouth and Women's Health Service Discipline of Physiology School of Medical SciencesThe University of Adelaide Discipline of Agricultural and Animal Science School of AgricultureFood and Wine The University of Adelaide Adelaide Sansom Institute for Health Research School of Pharmacy and Medical SciencesUniversity of South Australia

AIM: To examine the effect of increasing dietary zinc (Zn) intake and the lack of metallothionein (MT) expression on activity of small intestinal disaccharidases. METHODS: MT-Ⅰ and Ⅱ knockout (MT-/-) and wild-type (MT+/+) female mice at 3.5 wk of age were randomly fed with a diet containing 2 (2 Zn), 15 (15 Zn) or 50 (50 Zn) mg Zn/kg (n = 8/group/genotype) for 5 wk. Small intestinal segments (duodenum, jejunum and ileum) were collected and either fixed in 10% formalin for histological analysis or snap frozen in liquid nitrogen for sucrase, lactase and maltase activity ***: Plasma Zn was significantly (P jejunal sucrase and lactase activities were significantly higher in MT-/- (13 313 ± 2314; 4107 ± 364 μmol glucose/well/min/g tissue, respectively) compared with MT+/+ mice (7054 ± 608; 1818 ± 174). Similarly, ileal lactase activities were higher in MT-/- (1480 ± 192) compared with MT+/+ (629 ± 353) mice particularly those fed the 2 Zn diet. CONCLUSION: Increasing dietary Zn has little effect on disaccharidases activity in MT wild-type mice. The presence of MT may enhance morphological and functional development of the gut.

关键词： Lactase Maltase Sucrase Metallothionein Diet Zinc

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Latitudinal gradients of biodiversity and ecosystem services in protected and non-protected oak forest areas can inform climate smart conservation

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Geography and Sustainability 2024年第4期5卷 647-659页

作者： Anders Forsman johanna Sunde Romana Salis Markus Franzen Department of Biology and Environmental Science Linnaeus UniversitySE-39182KalmarSweden Department of Physics Chemistry and Biology(IFM)Linköing UniversitySE-58183LinköingSweden

Adaptive governance of areas set aside for future protection of biodiversity,sustainable production,and recreation requires knowledge about whether and how effects of area protection are modulated by climate change and redistribution of *** investigate this,we compare biodiversity of plants(assessed using vegetation plots)and arthropods(collected with Malaise traps,analyzed using metabarcoding)and productivity(tree growth,determined using dendrochronology)in protected and non-protected oak(Quercus spp.)forests along a latitudinal gradient(55.6°N–60.8°N)in *** also compare historical,recent and projected future climate in the *** contrast to established global latitudinal diversity gradients,species richness of plants and arthropods increased northwards,possibly reflecting recent climate-induced community redistributions,but neither was higher in protected than in non-protected areas,nor associated with contemporary ground *** composition of arthropods also did not differ between protected and non-protected *** biomass increased with latitude,suggesting that the magnitude of cascading effects mediated via their roles as pollinators,herbivores,and prey for other trophic levels,varies geographically and will change with a moving *** growth rate of oaks(an ecosystem service in the form of biomass increase and carbon sequestration)was independent of latitude and did not differ between protected and non-protected *** findings question the efficacy of contemporary designation and management of protected oak forests,and emphasize that development and implementation of modified climate smart conservation strategies is needed to safeguard ecosystem functioning,biodiversity,and recreational values of protected forest areas against future challenges.

关键词： Biological diversity Conservation biology Decision making Forest ecosystems Global warming Species-richness gradients

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