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Effect of Cambering on the Aerodynamic Performance of Heaving Airfoils

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Journal of Bionic Engineering 2009年第4期6卷 398-404,406-407页

作者： joel E.Guerrero Postdoctoral Research Fellow Department of CivilEnvironmental and Architectural EngineeringUniversity of GenoaVia Montallegro 1Genoa16145Italy

In the present work,a parametric numerical study is conducted in order to assess the effect of airfoil cambering on the aerodynamic performance of rigid heaving *** incompressible Navier-Stokes equations are solved in their velocity-pressure formulation using a second-order accurate in space and time finite-difference *** tackle the problem of moving boundaries,the governing equations are solved on overlapping structured *** numerical simulations are performed at a Reynolds number of Re=1100 and at different values of Strouhal number and reduced *** results obtained show that the airfoil cambering geometric parameter has a strong influence on the average lift coefficient,while it has a smaller impact on the average thrust coefficient and propulsive efficiency of heaving airfoils.

关键词： heaving airfoils structured overlapping grids incompressible Navier-Stokes equations airfoil cambering

基于“心脑一体观”探讨针灸调节褪黑素的作用机理

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中国医药科学 2024年第6期14卷 21-24页

作者： walker joel Mikael 王建明于冬冬王文哲韩乐河南中医药大学河南郑州450046

现代医学认为,脑主导机体的一切生命过程和精神活动,且与周围环境的平衡和调节存在关系。而中医认为“心者,君主之官,神明出焉”,心有主宰身体和神志的功能。褪黑素(MT)是脑室内松果体分泌的一种激素,其在人体的效应有类似中医理论中的... 详细信息

现代医学认为,脑主导机体的一切生命过程和精神活动,且与周围环境的平衡和调节存在关系。而中医认为“心者,君主之官,神明出焉”,心有主宰身体和神志的功能。褪黑素(MT)是脑室内松果体分泌的一种激素,其在人体的效应有类似中医理论中的“心”“神”作用。如何理解并且融通中医和现代医学两个不同的理论体系,是目前在临床和科研中的重要问题。“心脑一体观”是结合不同理论体系的对同一个生理现象的探讨。本研究基于“心脑一体观”探讨MT失调所致疾病的相关研究,阐释针灸通过调理“心”“神”相关的穴位组合,不仅可改善失眠、抑郁、肥胖、血管性痴呆、胃溃疡等疾病症状,同时具有调节MT水平的作用,为临床针灸治疗MT相关疾病的腧穴配伍提供理论依据。

关键词：心脑一体观褪黑素针灸松果体

Science： a world without borders

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Protein & Cell 2015年第8期6卷 551-552页

作者： joel Haywood CAS key Laboratory of Pathogenic Microbiology and Immunology Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China

In 2010 the effects of the global financial crisis were still being felt in the Uk. Stock market confidence levels were low, unemployment levels were high and job opportunities were few and far between especially for new graduates with little work experience. Unfortunately for my partner, her recent graduation and search for job opportunities within the finance and law sector could not have come at a more unsuitable time. China however had better weathered the storm of the financial crisis and presented itself as a more familiar and fruitful climate for my partner to further develop her career. Furthermore.

关键词： International Scientific Community Scientific Research Community Previous International Study Student Exchange Program Eminent Researcher

Exploring the tectonostratigraphy of the Pakistan Himalaya with new detrital zircon geochronology and neodymium isotope data from the kaghan Valley

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Geoscience Frontiers 2023年第6期14卷 117-132页

作者： w.joel Schiffer Delores M.Robinson Shah Faisal Harold H.Stowell Department of Geological Sciences and Center for Sedimentary Basin Studies University of AlabamaPO Box 870338TuscaloosaAL 35487USA National Centre of Excellence in Geology University of PeshawarPeshawar 25130Pakistan

In the central Himalaya,the Greater and Lesser Himalayan tectonostratigraphic zones can be distinguished from each other by combining detrital zircon U-Pb ages and whole-rock Nd isotopic *** the Hazara-kashmir syntaxis of northern Pakistan,rock units in the kaghan valley have been variously assigned to the Tethyan,Greater,and Lesser Himalayan *** determine which tectonostratigraphic zones are represented,we sampled across the Batal thrust in the northern kaghan valley because this structure is identified in some research as the Main Central *** from the footwall yield Paleo-to Mesoproterozoic maximum depositional ages(-1.8-1.1 Ga)and an averageεNd(0)value *** from the hanging wall yield Neoproterozoic maximum depositional ages(~1000-600 Ma)andεNd(0)values *** contrasting detrital zircon ages show that the Batal thrust in the kaghan valley is a major structural ***,these data lack the characteristic detrital zircon age spectra andεNd(0)values of Greater and Lesser Himalayan rocks north and south of the Main Central thrust in the central Himalaya,***,either the Batal thrust is not the Main Central thrust,or the Main Central thrust in the kaghan valley cuts a different structural level and carries rock units not seen outside the Hazara-kashmir syntaxis.

关键词： Pakistan Himalaya Tectonostratigraphy Main Central thrust Detrital zircon geochronology Neodymium isotopes

The evolution and refinements of varicocele surgery

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Asian Journal of Andrology 2016年第2期18卷 171-178,J0002页

作者： joel L Marmar Director of Men's Health Services Planned Parenthood of Southern New Jersey 317 S. Broadway Camden NJ 08103 USA.

Varicoceles had been recognized in clinical practice for over a century. Originally, these procedures were utilized for the management of pain but, since 1952, the repairs had been mostly for the treatment of male infertility. However, the diagnosis and treatment of varicoceles were controversial, because the pathophysiology was not clear, the entry criteria of the studies varied among centers, and there were few randomized clinical trials. Nevertheless, clinicians continued developing techniques for the correction of varicoceles, basic scientists continued investigations on the pathophysiology of varicoceles, and new outcome data from prospective randomized trials have appeared in the world＇s literature. Therefore, this special edition of the Asian Journal of Andrology was proposed to report much of the new information related to varicoceles and, as a specific part of this project, the present article was developed as a comprehensive review of the evolution and refinements of the corrective procedures.

关键词： antegrade sclerosis laparoscopic varicocelectomy microsurgical varicocelectomy percutaneous embolization varicocelectorny

ON THE ALGORITHMIC COMPLEXITY OF STATIC STRUCTURES

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Journal of Systems Science & Complexity 2010年第6期23卷 1037-1053页

作者： joel RATSABY J. CHASkALOVIC joel RATSABY Dept. of Electrical and Electronics Engineering Ariel University Center of Samaria Ariel Israel Department of Mathematics Ariel University Center of Samaria Ariel Israel and IJLRDA University Pierre and Marie Curie-Paris VI France.

This paper provides a first indication that this is true for a system comprised of a static structure described by hyperbolic partial differential equations and is subjected to an external random input force. The system deforms the randomness of an input force sequence in proportion to its algorithmic complexity. The authors demonstrate this by numerical analysis of a one-dimensional vibrating elastic solid （the system） on which we apply a maximally-random force sequence （input）. The level of complexity of the system is controlled via external parameters. The output response is the field of displacements observed at several positions on the body. The algorithmic complexity and stochasticity of the resulting output displacement sequence is measured and compared against the complexity of the system. The results show that the higher the system complexity, the more random-deficient the output sequence.

关键词： Data compression descriptional complexity randomness static structure.

CUTIN SYNTHASE 2 Maintains Progressively Developing Cuticular Ridges in Arabidopsis Sepals

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Molecular Plant 2017年第4期10卷 560-574页

作者： Lilan Hong joel Brown Nicholas A. Segerson Jocelyn k.C. Rose Adrienne H.k. Roeder weiil institute for Ceil and Molecular Biology Cornell University Ithaca NY 14853 USA Plant Biology Section School of Integrative Plant Science Cornell University Ithaca NY 14853 USA Field of Genetics Genomics and Development Cornell University Ithaca NY 14853 USA

The cuticle is a crucial barrier on the aerial surfaces of land plants, in many plants, including Arabidopsis, the sepals and petals form distinctive nanoridges in their cuticles. However, little is known about how the formation and maintenance of these nanostructures is coordinated with the growth and development of the underlying cells. Here we report the characterization of the Arabidopsis cutin synthase 2 （cus2） mutant, which causes a great reduction in cuticular ridges on the mature sepal epidermis, but only a moderate effect on petal cone cell ridges. Using scanning electron microscopy and confocal live imaging combined with quantification of cellular growth, we find that cuticular ridge formation progresses down the sepal from tip to base as the sepal grows, pCUS2：：GFP-GUS reporter expression coincides with cutic- ular ridge formation, descending the sepal from tip to base. Ridge formation also coincides with the reduction in growth rate and termination of cell division of the underlying epidermal cells. Surprisingly, cuticular ridges at first form normally in the cus2 mutant, but are lost progressively at later stages of sepal development, indicating that CUS2 is crucial for the maintenance of cuticular ridges after they are formed~ Our results reveal the dynamics of both ridge formation and maintenance as the sepal grows.

关键词： Arabidopsis thaliana cellular growth CUTIN SYNTHASE2 (CUS2) cuticular ridges nanoridges sepal

Achieving timely percutaneous reperfusion for rural ST-elevation myocardial infarction patients by direct transport to an urban PCI-hospital

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Journal of Geriatric Cardiology 2016年第10期13卷 840-845页

作者： Charles-Lwanga k Bennin Saif Ibrahim Farah Al-Saffar Lyndon C Box joel A Strom Valley Cardiology Fayetteville North Carolina USA Division of Cardiology Department of Medicine University of Florida College of Medieine Jacksonville Jaeksonville Florida USA Division of Cardiovascular Diseases Mayo Clinic Seottsdale Arizona USA west Valley Medical Group Caldwell Idaho USA Florida Polytechnic University Lakeland Florida USA

Backgrounds ST-elevation myocardial infarction （STEMI） guidelines recommend reperfusion by primary percutaneous coronary in- tervention （PCI） ≤ 90 min from time of first medical contact （FMC）. This strategy is challenging in rural areas lacking a nearby PCI-capable hospital. Recommended reperfusion times can be achieved for STEMI patients presenting in rural areas without a nearby PCI-capable hospital by ground transportation to a central PCI-capable hospital by use of protocol-driven emergency medical service （EMS） STEMI field triage protocol. Methods Sixty STEMI patients directly transported by EMS from three rural counties （Nassau, Camden and Charlton Counties） within a 50-mile radius of University of Florida Health-Jacksonville （UFHJ） from 01/01/2009 to 12/31/2013 were identified from its PCI registry. The STEMI field triage protocol incorporated three elements：（1） a cooperative agreement between each of the rural emergency medical service （EMS） agency and UFHJ; （2） performance of a pre-hospital ECG to facilitate STEMI identification and laboratory activation; and （3） direct transfer by ground transportation to the UFHJ cardiac catheterization laboratory. FMC-to-device （FMC2D）, door-to-device （D2D）, and transit times, the day of week, time of day, and EMS shift times were recorded, and odds ratio （OR） of achieving FMC2D times was calculated. Results FMC2D times were shorter for in-state STEMIs （81 ± 17 vs. 87± 19 min）, but D2D times were similar （37 ± 18 vs. 39 ± 21 min）. FMC2D 〈 90 min were achieved in 82.7% in-state STEMIs compared to 52.2% for out-of-state STEMIs （OR = 4.4, 95% CI： 1.24-15.57; P = 0.018）. FMC2D times were homogenous after adjusting for weekday vs. weekend, EMS shift times. Nine patients did not meet FMC2D ≤ 90 min. Six were within 10 min of target; all patient achieved FMC2D 〈 120 min. Conclusions Guideline-compliant FMC2D ≤90 min is achievable for rural STEMI patients within a 50 mile radius of a PCI-capable hospital by use of protocol-driv

关键词： Myocardial infarction Percutaneous coronary intervention Systems of care

Obesity:an evolutionary context

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Life Metabolism 2022年第1期1卷 10-24页

作者： John R.Speakman joel k.Elmquist Shenzhen key Laboratory of Metabolic Health Center for Energy Metabolism and ReproductionShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhenChina School of Biological Sciences University of AberdeenAberdeenUK State key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental biologyChinese Academy of SciencesBeijingChina CAS Center of Excellence in Animal Evolution and Genetics KunmingChina Departments of Internal Medicine and Pharmacology Center for Hypothalamic ResearchUniversity of Texas SouthwesternDallasTXUSA

People completely lacking body fat(lipodystrophy/lipoatrophy)and those with severe obesity both show profound metabolic and other health *** levels of body fat somewhere between these limits would,therefore,appear to be *** different models might be *** traditional is a set point(SP)where the levels are regulated around a fixed ***,dual-intervention point(DIP)is a system that tolerates fairly wide variation but is activated when critically high or low levels are *** DIP system seems to fit our experience much better than an SP,and models suggest that it is more likely to have evolved.A DIP system may have evolved because of two contrasting selection *** the lower end,we may have been selected to avoid low levels of fat as a buffer against starvation,to avoid disease-induced anorexia,and to support *** the upper end,we may have been selected to avoid excess storage because of the elevated risks of *** upper limit of control seems to have malfunctioned because some of us deposit large fat stores,with important negative health *** has evolution not protected us against this problem?One possibility is that the protective system slowly fell apart due to random mutations after we dramatically reduced the risk of being predated during our evolutionary *** chance,it fell apart more in some people than others,and these people are now unable to effectively manage their weight in the face of the modern food *** understand the evolutionary context of obesity,it is important to separate the adaptive reason for storing some fat(*** lower intervention point),from the nonadaptive reason for storing lots of fat(a broken upper intervention point).The DIP model has several consequences,showing how we understand the obesity problem and what happens when we attempt to treat it.

关键词： obesity BMI body fat adiposity evolution selection adaptive leptin resistance metabolic programming dual-intervention point model set-point model