检索结果-南通市图书馆

Integrins and their potential roles in mammalian pregnancy

Journal of Animal Science and Biotechnology 2024年第1期15卷 1-19页

作者： Gregory A.Johnson Robert C.Burghardt Fuller W.Bazer Heewon Seo joe W.Cain Department of Veterinary Integrative Biosciences School of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityCollege StationTX 77843‑4459USA Department of Animal Science College of Agriculture and Life SciencesTexas A&M UniversityCollege StationTX 77843‑2471USA

Integrins are a highly complex family of receptors that, when expressed on the surface of cells, can mediate reciprocal cell-to-cell and cell-to-extracellular matrix(ECm) interactions leading to assembly of integrin adhesion complexes(IACs) that initiate many signaling functions both at the membrane and deeper within the cytoplasm to coordinate processes including cell adhesion, migration, proliferation, survival, differentiation, and metabolism. All metazoan organisms possess integrins, and it is generally agreed that integrins were associated with the evolution of multicellularity, being essential for the association of cells with their neighbors and surroundings, during embryonic development and many aspects of cellular and molecular biology. Integrins have important roles in many aspects of embryonic development, normal physiology, and disease processes with a multitude of functions discovered and elucidated for integrins that directly influence many areas of biology and medicine, including mammalian pregnancy, in particular implantation of the blastocyst to the uterine wall, subsequent placentation and conceptus(embryo/fetus and associated placental membranes) development. This review provides a succinct overview of integrin structure, ligand binding, and signaling followed with a concise overview of embryonic development, implantation, and early placentation in pigs, sheep, humans, and mice as an example for rodents. A brief timeline of the initial localization of integrin subunits to the uterine luminal epithelium(LE) and conceptus trophoblast is then presented, followed by sequential summaries of integrin expression and function during gestation in pigs, sheep, humans, and rodents. As appropriate for this journal, summaries of integrin expression and function during gestation in pigs and sheep are in depth, whereas summaries for humans and rodents are brief. Because similar models to those illustrated in Fig. 1, 2, 3, 4, 5 and 6 are present throughout the sc

关键词： Humans Implantation Integrins Pigs Pregnancy Rodents Sheep

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Crystal reconstruction of V2O3/carbon heterointerfaces via anodic hydration for ultrafast and reversible mg-ion battery cathodes

引用

Infomat 2024年第3期6卷 95-107页

作者： Gun Jang Yun Sang joe Sang Joon Lee Hyun Gyu Cho Sang Ha Baek Peixun Xiong Kang Ho Shin Jeong Seok Yeon min Su Kang Si Hyoung Oh Ho Seok Park School of Chemical Engineering Sungkyunkwan University(SKKU)SuwonRepublic of Korea Advanced Batteries Research Center Korea Electronics Technology InstituteSeongnamRepublic of Korea Korea Institute of Science and Technology SeoulRepublic of Korea SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan UniversitySuwonRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan UniversitySuwonRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea

magnesium-ion batteries(mIBs)have promising applications because of their high theoretical capacity and the natural abundance of magnesium ***,the kinetic performance and cyclic stability of cathode materials are limited by the strong interactions between mg ions and the crystal ***,we demonstrate the unique mg^(2+)-ion storage mechanism of a hierarchical accordion-like vanadium oxide/carbon heterointerface(V2O3@C),where the V2O3 crystalline structure is reconstructed into a mgV_(3)O_(7)·H_(2)O phase through an anodic hydration reaction upon first cycle,for the improved kinetic and cyclic *** verified by in situ/ex situ spectroscopic and electrochemical analyses,the fast charge transfer kinetics of the V2O3@C cathode were due to the crystal-reconstruction and chemically coupled *** V2O3@C demonstrated an ultrahigh rate capacity of 130.4 mAh g^(-1)at 50000 mA g^(-1)and 1000 cycles,achieving a Coulombic efficiency of 99.6%.The high capacity of 381.0 mA h g^(-1)can be attributed to the reversible mg^(2+)-ion intercalation mechanism observed in the mgV_(3)O_(7)·H_(2)O phase using a 0.3 m mg(TFSI)2/ACN(H_(2)O)***,within the voltage range of 2.25 V versus mg/mg^(2+),the V2O3@C exhibited a capacity of 245.1 mAh g^(-1)when evaluated with magnesium metal in a 0.3 m mg(TFSI)^(2+)0.25 m mgCl_(2)/DmE *** research findings have important implications for understanding the relationship between the mg-ion storage mechanism and reconstructed crystal phase of vanadium oxides as well as the heterointerface reconstruction for the rational design of mIB cathode materials.

关键词： anodic hydration reaction magnesium ion battery nano crystal vanadium oxide

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

John 5给初学者与专业吉他手的实用建议

引用

乐器 2024年第7期 110-111页

作者： joe Bosso Slowly(译) 不详

John 5是一位精通多种风格的吉他大师,曾与Lynyrd Skynyrd、David Lee Roth、Rick Springf ield合作演出,现在更是加入到m?tley Crüe,他为乐手提供的指导远不止练习方法这么简单。任何能将乡村风格的chicken pickin'技法与金属速弹相... 详细信息

John 5是一位精通多种风格的吉他大师,曾与Lynyrd Skynyrd、David Lee Roth、Rick Springf ield合作演出,现在更是加入到m?tley Crüe,他为乐手提供的指导远不止练习方法这么简单。任何能将乡村风格的chicken pickin'技法与金属速弹相结合的吉他手,绝不仅仅是“一招吃天下”。在他的职业生涯中,John 5将多样性作为自己的一张名片,他提供的吉他服务受到了众多艺术家的青睐,其中包括***、marilyn manson、Wilson Phillips、Lynyrd Skynyrd、David Lee Roth、Rick Springfield、Salt-N-Pepa等。

关键词：吉他手合作演出实用建议乡村风格练习方法多种风格职业生涯

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Surgical intervention combined with weight-bearing walking training promotes recovery in patients with chronic spinal cord injury:a randomized controlled study

引用

Neural Regeneration Research 2024年第12期19卷 2773-2784页

作者： Hui Zhu James D.Guest Sarah Dunlop Jia-Xin Xie Sujuan Gao Zhuojing Luo joe E.Springer Wutian Wu Wise Young Wai Sang Poon song Liu Hongkun Gao Tao Yu Dianchun Wang Libing Zhou Shengping Wu Lei Zhong Fang Niu Xiaomei Wang Yansheng Liu Kwok-Fai So Xiao-ming Xu Kunming Tongren Hospital KunmingYunnan ProvinceChina Neurological Surgery and the Miami Project to Cure ParalysisMiller School of MedicineUniversity of MiamiMiamiFLUSA School of Biological Sciences The University of Western AustraliaPerthWAAustralia minderoo Foundation PerthWAAustralia Clinical Center for Spinal Cord Injury Kunming General Hospital of Chengdu Military CommandKunmingYunnan ProvinceChina Department of Biostatistics and Health Data Science Indiana University School of MedicineIndianapolisINUSA Department of Orthopedic Spinal Surgery Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Spinal Cord and Brain Injury Research Center Department of Physical Medicine and RehabilitationUniversity of Kentucky College of MedicineLexingtonKYUSA Guangdong-HongKong-macao Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina W.m.Keck Center for Collaborative Neuroscience Rutgers UniversityPiscatawayNJUSA Neurosurgery Department Chinese University of Hong KongPrince of Wales HospitalHong Kong Special Administration RegionChina Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA

For patients with chronic spinal cord injury,the co nventional treatment is rehabilitation and treatment of spinal cord injury complications such as urinary tract infection,pressure sores,osteoporosis,and deep vein *** is rarely perfo rmed on spinal co rd injury in the chronic phase,and few treatments have been proven effective in chronic spinal cord injury *** of effective therapies fo r chronic spinal co rd injury patients is *** conducted a randomized controlled clinical trial in patients with chronic complete thoracic spinal co rd injury to compare intensive rehabilitation(weight-bearing walking training)alone with surgical intervention plus intensive *** clinical trial was registered at ***(NCT02663310).The goal of surgical intervention was spinal cord detethering,restoration of cerebrospinal fluid flow,and elimination of residual spinal cord *** found that surgical intervention plus weight-bearing walking training was associated with a higher incidence of American Spinal Injury Association Impairment Scale improvement,reduced spasticity,and more rapid bowel and bladder functional recovery than weight-bearing walking training ***,the surgical procedures and intensive rehabilitation were *** Spinal Injury Association Impairment Scale improvement was more common in T7-T11 injuries than in T2-T6 *** combined with rehabilitation appears to have a role in treatment of chronic spinal cord injury patients.

关键词： chronic spinal cord injury intensive rehabilitation locomotor training neurological recovery surgical intervention weightbearing walking training

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Imbalanced Dataset and Class Overlapping Classification model for Big Data

引用

Computer Systems Science & Engineering 2023年第2期44卷 1009-1024页

作者： mini Prince P.m.joe Prathap Department of Information Technology St.Peter’s College of Engineering and TechnologyChennai600054TamilnaduIndia Department of Information Technology R.M.D Engineering CollegeChennai601206TamilnaduIndia

most modern technologies,such as social media,smart cities,and the internet of things(IoT),rely on big *** big data is used in the real-world applications,two data challenges such as class overlap and class imbalance *** dealing with large datasets,most traditional classiﬁers are stuck in the local optimum *** a result,it’s necessary to look into new methods for dealing with large data *** solutions have been proposed for overcoming this *** rapid growth of the available data threatens to limit the usefulness of many traditional *** such as oversampling and undersampling have shown great promises in addressing the issues of class *** all of these techniques,Synthetic minority Oversampling TechniquE(SmOTE)has produced the best results by generating synthetic samples for the minority class in creating a balanced *** issue is that their practical applicability is restricted to problems involving tens of thousands or lower instances of *** this paper,we have proposed a parallel mode method using SmOTE and mapReduce strategy,this distributes the operation of the algorithm among a group of computational nodes for addressing the aforementioned *** proposed solution has been divided into three ***ﬁrst stage involves the process of splitting the data into different blocks using a mapping function,followed by a pre-processing step for each mapping block that employs a hybrid SmOTE algo-rithm for solving the class imbalanced *** each map block,a decision tree model would be ***,the decision tree blocks would be com-bined for creating a classiﬁcation *** have used numerous datasets with up to 4 million instances in our experiments for testing the proposed scheme’s *** a result,the Hybrid SmOTE appears to have good scalability within the framework proposed,and it also cuts down the processing time.

关键词： Imbalanced dataset class overlapping SmOTE mapReduce parallel programming oversampling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A stochastic approach for integrating market and technical uncertainties in economic evaluations of petroleum development

引用

Petroleum Science 2009年第3期6卷 319-326页

作者： Changhyup Park joe m. Kang Taewoong Ahn BK21 Research Division for Energy Resources Seoul National University Division of Energy Systems Engineering Seoul National University

The paper presents a stochastic and economic analysis for petroleum development under uncertain market and technical environments. mean-reversion with jumps for price forecasting is used to consider market uncertainty, while various scenarios for the reservoir properties and cost are employed to consider technical uncertainty. monte Carlo simulation is carried out to obtain the feasible range of net present values and internal rates of return. The influence of stochastic parameters is examined through correlation coefficients. The stochastic approach yields more reliable evaluation and effectively investigates the characteristics of development. The integration of uncertainties and contractual terms results in an irregular tendency in the future cash flow and reveals that a larger reserve does not guarantee a greater profit. The reserve and the well rate affect the economic values whereas the parameters for price prediction don＇t. The research confirms the necessity of qualifying uncertainties for realistic decision-making at the initial stage of development.

关键词： Uncertainty petroleum development decision-making stochastic approach mean reversion with jumps

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Alcohol,inflammation,and gut-liver-brain interactions in tissue damage and disease development

引用

World Journal of Gastroenterology 2010年第11期16卷 1304-1313页

作者： H joe Wang Samir Zakhari m Katherine Jung Division of metabolism and Health Effects National Institute on Alcohol Abuse and Alcoholism National Institutes of Health

Chronic inflammation is often associated with alcoholrelated medical conditions. The key inducer of such inflammation, and also the best understood, is gut microflora-derived lipopolysaccharide (LPS). Alcohol can significantly increase the translocation of LPS from the gut. In healthy individuals, the adverse effects of LPS are kept in check by the actions and interactions of multiple organs. The liver plays a central role in detoxifying LPS and producing a balanced cytokine milieu. The central nervous system contributes to anti-inflammatory regulation through neuroimmunoendocrine actions. Chronic alcohol use impairs not only gut and liver functions, but also multi-organ interactions, leading to persistent systemic inflammation and ultimately, to organ damage. The study of these interactions may provide potential new targets for therapeutic intervention.

关键词： Chronic alcohol use Chronic inflammation Li- popolysaccharides Pro-inflammatory and anti-inflammatory cytokines Kupffer cells monocytes Tumor necrosis factor α Interleukin-10 Neuroendocrine Hypothalamo-pituitary-adrenal axis Glucocorticoid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Novel Approach to Design Distribution Preserving Framework for Big Data

引用

Intelligent Automation & Soft Computing 2023年第3期35卷 2789-2803页

In several fields like financial dealing,industry,business,medicine,et cetera,Big Data(BD)has been utilized extensively,which is nothing but a collection of a huge amount of ***,it is highly complicated along with time-consuming to process a massive amount of ***,to design the Distribution Preserving Framework for BD,a novel methodology has been proposed utilizing manhattan Distance(mD)-centered Partition Around medoid(mD–PAm)along with Conjugate Gradient Artificial Neural Network(CG-ANN),which undergoes various steps to reduce the complications of ***,the data are processed in the pre-processing phase by mitigating the data repetition utilizing the map-reduce function;subsequently,the missing data are handled by substituting or by ignoring the missed *** that,the data are transmuted into a normalized ***,to enhance the classification performance,the data’s dimensionalities are minimized by employing Gaussian Kernel(GK)-Fisher Discriminant Analysis(GK-FDA).Afterwards,the processed data is submitted to the partitioning phase after transmuting it into a structured *** the partition phase,by utilizing the mD-PAm,the data are partitioned along with grouped into a ***,by employing CG-ANN,the data are classified in the classification phase so that the needed data can be effortlessly retrieved by the *** analogize the outcomes of the CG-ANN with the prevailing methodologies,the NSL-KDD openly accessible datasets are *** experiential outcomes displayed that an efficient result along with a reduced computation cost was shown by the proposed *** proposed work outperforms well in terms of accuracy,sensitivity and specificity than the existing systems.

关键词： Big data artiﬁcial neural network ﬁsher discriminant analysis distribution preserving framework manhattan distance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The biological stress of early weaned piglets

引用

Journal of Animal Science and Biotechnology 2013年第2期4卷 124-127页

作者： Joy m Campbell joe D Crenshaw Javier Polo APC Inc. 2425 SE Oak Tree CourtAnkenyIA USA

Pigs experience biological stress such as physiological, environmental, and social challenges when weaned from the sow. The process of weaning is one of the most stressful events in the pig＇s life that can contribute to intestinal and immune system dysfunctions that result in reduced pig health, growth, and feed intake, particularly during the first week after weaning. Technological improvements in housing, nutrition, health, and management have been used to minimize some of the adverse effects of weaning stress, but a greater understanding of the biological impact of stress is needed to improve strategies to overcome weaning stress. The focus of this review paper is to briefly describe how the biological stress associated with weaning impacts intestinal morphology, structure, physiology, and intestinal immune responses that can impact subsequent production efficiencies such as growth, intake, morbidity, and mortality.

关键词： Biological stress Intestine Pig Weaning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

DEGREE 3 ALGEBRAIC mINImAL SURFACES IN THE 3-SPHERE

引用

Acta mathematica Scientia 2012年第6期32卷 2065-2084页

作者： joe S.Wang 4 Ricado Ln St.LauisM063124USA

We give a local analytic characterization that a minimal surface in the 3-sphere S3 C R4 defined by an irreducible cubic polynomial is one of the Lawson＇s minimal tori. This provides an alternative proof of the result by Perdomo （Characterization of order 3 algebraic immersed minimal surfaces of S3, Geom. Dedicata 129 （2007）, 23 34）.

关键词： algebraic minimal surface 3-sphere cubic polynomial

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：