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Developing a chloramine decay index to understand nitrification:A case study of two chloraminated drinking water distribution systems

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Journal of Environmental Sciences 2017年第7期29卷 170-179页

作者： Sina Moradi Sanly Liu christopher W.k.chow John van Leeuwen David cook Mary Drikas rose Amal School of chemical Engineering The University of New South Wales Australian Water Quality centre SA Water Corporation centre for Water Management and Reuse School of Natural and Built EnvironmentsUniversity of South Australia

The management of chloramine decay and the prevention of nitrification are some of the critical issues faced by water utilities that use chloramine as a *** this study,potential association between high performance size exclusion chromatography（HPSEc）data obtained with multiple wavelength Ultraviolet（UV） detection from two drinking water distribution systems in Australia and nitrification occurrence was *** increase in the absorbance signal of HPSEc profiles with UV detection at λ = 230 nm between apparent molecular weights of 200 to 1000 Da was observed at sampling sites that experienced rapid chloramine decay and nitrification while its absorbance signal at λ =254 nm decreased.A chloramine decay index（c.D.I） defined as the ratio of area beneath the HPSEc spectra at two different wavelengths of 230 and 254 nm,was used in assessing chloramine decay *** *** of waters at locations that experienced nitrification were consistently higher than locations not experiencing nitrification.A simulated laboratory study showed that the formation of nitrite/nitrate and/or soluble microbial products and/or the release of extracellular polymeric substances（EPS） during nitrification may contribute to the *** findings suggest that c.D.I derived from HPSEc with multiple wavelength UV detection could be an informative index to track the occurrence of rapid chloramine decay and nitrification.

关键词： HPSEc Water distribution systems Nitrification chloramine decay

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Hydrogen sutfide protects colon cancer cells from chemopreventative agent β-phenylethyl isothiocvanate induced apoptosis

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World Journal of Gastroenterology 2005年第26期11卷 3990-3997页

作者： Peter rose Philip k Moore Shen Han Ming Ong choon Nam Jeffrey S Armstrong Matt Whiteman Department of Biochemistry National University of Singapore 8 Medical Drive117597Singapore Department of Pharmacology National University of Singapore 18 Medical Drive117597 Singapore Department of community Occupational and Family Medicine National University of Singapore 16 Medical Drive 117597 Singapore

AIM:Hydrogen sulfide (H2S) is a prominent gaseous constituent of the gastrointestinal (GI) tract with known cytotoxic properties. Endogenous concentrations of H2S are reported to range between 0.2-3.4 mmol/L in the GI tract of mice and humans. considering such high levels we speculate that, at non-toxic concentrations, H2S may interact with chemical agents and alter the response of colonic epithelium cells to such compounds. The GI tract is a major site for the absorption of phytochemical constituents such as isothiocyanates, flavonoids, and carotenoids, with each group having a role in the prevention of human diseases such as colon cancer. The chemopreventative properties of the phytochemical agent p-phenyethyl isothiocyanate (PEITc) are well recognized. However, little is currently known about the physiological or biochemical factors present in the GI tract that may influence the biological properties of ITcs. The current study was undertaken to determine the effects of H2S on PEITc mediated apoptosis in colon cancer cells. METHODS: Induction of apoptosis by PEITc in human colon cancer HcT116 cells was assessed using classic apoptotic markers namely SubGl population analysis, caspase-3 like activity and nuclear fragmentation and condensation coupled with the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrasodium bromide) viability assay and LDH leakage. RESULTS: PEITc significantly induced apoptosis in HcT116 cells as assessed by SubGl population formation, nuclear condensation, LDH leakage and caspase-3 activity after 24 h, these data being significant from control groups (Pcontrast, co-treatment of cells with physiological concentrations of H2S (0.1-1 mmol/L) prevented PEITc mediated apoptosis as assessed using the parameters described. cONcLUSION: PEITc effectively induced cell death in the human adenocarcinoma cell line HcT116 in vitro through classic apoptotic mechanisms. However, in the presence of H2S, apoptosis was abolished. These data sugg

关键词： Apoptosis colon cancer Hydrogen sulfide β-phenylethyl isothiocyanate

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THE NONLINEAR INTERAcTION OF VORTEX RINGS WITH A FREE SURFAcE

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Acta Mechanica Sinica 1997年第2期13卷 120-129页

作者：叶取源 c.k.chu Dept.of Engineering Mechanics Shanghai Jiao Tong UniversityShanghai 200030China Dept.of Applied Physics Columbia UniversityNew YorkNY 10027USA

Nonlinear interactions of vortex rings with a free surface are considered in an incompressible, ideal fluid using the vortex contour dynamics technique and the boundary integral equation method. The flow is axisymmetric and the vorticity is linearly distributed in the vortex. Effects of the gravity and the surface tension as well as the initial geometric parameter of the vortex on the interaction process are investigated in considerable detail. The interaction process may be divided into three major stages: the vortex free-traveling stage, the collision stage, and the vortex stretching and rebounding stage. Time evolutions of both the vortex and free surface under various conditions are provided and analyzed. Two kinds of waves exist on the free surface during interaction. In a special case where the gravity and surface tension are very weak or the vortex is very strong, an electric-bulb-like 'cavity' is formed an the free surface and the vortex is trapped in the 'cavity' for quite a. long time, resulting in a large amount, of fluid above the mean fluid surface.

关键词： vortex ring vortex dynamics contour dynamics nonlinear free surface

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character recognition based on non-linear multi-projection profiles measure

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Frontiers of computer Science 2015年第5期9卷 678-690页

作者： k c SANTOSH Laurent WENDLING US National Library of Medicine (NLM) National Institutes of Health (NIH) Bethesda MD 20894 USA SIP-LIPADE Universit6 Pads Descartes (Pads V) Pads 75270 Cedex 06 France

In this paper, we study a method for isolated handwritten or hand-printed character recognition using dynamic programming for matching the non-linear multi- projection profiles that are produced from the Radon transform. The idea is to use dynamic time warping （DTW） algorithm to match corresponding pairs of the Radon features for all possible projections. By using DTW, we can avoid compressing feature matrix into a single vector which may miss information. It can handle character images in different shapes and sizes that are usually happened in natural hand- writing in addition to difficulties such as multi-class similarities, deformations and possible defects. Besides, a comprehensive study is made by taking a major set of state-of- the-art shape descriptors over several character and numeral datasets from different scripts such as Roman, Devanagari, Oriya, Bangla and Japanese-katakana including symbol. For all scripts, the method shows a generic behaviour by providing optimal recognition rates but, with high computational cost.

关键词： character recognition the Radon features dynamic programming shape descriptors

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NEcAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael k.E.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal EF-hand calcium-binding proteins 1–3(NEcAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one EF-hand calcium-binding domain and a functionally less well characterized c-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NEcAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NEcAB2 interacts with predominantly striatal G-protein-coupled receptors, while NEcAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NEcAB proteins exhibit distinct subcellular localizations: NEcAB1 is found in the nucleus and cytosol, NEcAB2 resides in endosomes and the plasma membrane, and NEcAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NEcAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NEcAB proteins by controlling the availability of protein–protein interaction domains situated between the EF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium EF hand mitochondria nervous system signal transduction

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Ensuring adequate statistics in particle tracking experiments

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Particuology 2021年第6期19卷 43-54页

作者： c.R.k.Windows-Yule School of chemical Engineering University of BirminghamEdgbastonBirmingham B152TTUnited Kingdom Institute for Multiscale Simulation Engineering of Advanced MaterialsFriedrich-Alexander Universitat Erlangen-NurnbergSchloBplatz 491054 ErlangenGermany

Particle tracking techniques such as magnetic particle tracking,radioactive particle tracking and positron emission particle tracking are widely used in academia and industry to image the dynamics of particulate and multiphase *** techniques can provide detailed data concerning a range of important,whole-field quantities based only on the time-averaged dynamics of a small number of tracer ***,in order for this data to be reliable,the duration over which these time-averages are taken must be suitably ***,the‘minimum averaging time’required to produce good statistics depends sensitively on the system in question and,at present,cannot be determined a priori in advance of an *** this paper,we take a step toward resolving this issue,using discrete element method simulations of a simple vibroﬂuidised granular bed to develop a series of scaling laws relating said minimum averaging time to a variety of key system *** scaling laws developed may be used by future experimentalists to predict the required averaging time for each given system during an experimental campaign,thus improving both the efficiency with which particle tracking techniques may be applied,and the reliability of the data produced thereby.

关键词： Granular Particle tracking Positron emission particle tracking Radioactive particle tracking Magnetic particle tracking Particle tracking velocimetry

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Laboratory scale study of an industrial phosphate and thermal treatment for polluted dredged sediments

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International Journal of Sediment Research 2012年第4期27卷 538-546页

作者： Souhila kRIBI jocelyn RAMAROSON Ange NZIHOU Patrick SHARROck Guy DEPELSENAIRE Ecole des Mines d'Albi-carmaux RAPSODEE UMR-CNRS 2392Route de Teillet-81013 ALBI CT Cedex 09France Ph.D. Paul Sabatier University Solvay DCRTRue de Ransbeek 310BrusselsBelgium

Dredged sediments are being chemically treated with phosphoric acid on an industrial *** effectiveness of the treatment was evaluated by performing the chemical reaction in a tubular reactor, followed by convective drying and maturation of the treated sediment at ambient temperature and finally thermal destruction of the organic matter by calcinations(500℃-900℃).The influence of acid concentration and calcination temperature on the specific surface area of the sediment was investigated. The stabilization of the heavy metals was evaluated by leaching tests and sequential extraction *** phosphoric acid treatment is effective in reducing heavy metal mobility,a prerequisite for recycling the sediments in various construction materials.

关键词： Dredged sediments Heavy metal pollution chemical treatment Thermal treatment

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The Development of a Renewable-Energy-Driven Reverse Osmosis System for Water Desalination and Aquaculture Production

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Journal of Integrative Agriculture 2013年第8期12卷 1357-1362页

作者： clark c k Liu Department of civil and Environmental Engineering and Water Resources Research CenterUniversity of Hawaii at Manoa

Water and energy are closely linked natural resources - the transportation, treatment, and distribution of water depends on low-cost energy; while power generation requires large volumes of water. Seawater desalination is a mature technology for increasing freshwater supply, but it is essentially a trade of energy for freshwater and is not a viable solution for regions where both water and energy are in short supply. This paper discusses the development and application of a renewable-energy-driven reverse osmosis （RO） system for water desalination and the treatment and reuse of aquaculture wastewater. The system consists of （1） a wind-driven pumping subsystem, （2） a pressure-driven RO membrane desalination subsystem, and （3） a solar-driven feedback control module. The results of the pilot experiments indicated that the system, operated under wind speeds of 3 m s-~ or higher, can be used for brackish water desalination by reducing the salinity of feedwater with total dissolved solids （TDS） of over 3 000 mg L-1 to product water or permeate with a TDS of 200 mg L-~ or less. Results of the pilot experiments also indicated that the system can remove up to 97% of the nitrogenous wastes from the fish pond effluent and can recover and reuse up to 56% of the freshwater supply for fish pond operation.

关键词： renewable energy desalination pressure-driven membrane processes aquaculture fish pond

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Generalized passivity-based chaos synchronization

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Applied Mathematics and Mechanics(English Edition) 2010年第8期31卷 1009-1018页

作者： c.k.AHN Faculty of the Division of Electronics and control Engineering Wonkwang University

In this paper, a new passivity-based synchronization method for a general class of chaotic systems is proposed. Based on the Lyapunov theory and the linear matrix inequality （LMI） approach, the passivity-based controller is presented to make the synchronization error system not only passive but also asymptotically stable. The proposed controller can be obtained by solving a convex optimization problem represented by the LMI. Simulation studies for the Genesio-Tesi chaotic system and the Qi chaotic system are presented to demonstrate the effectiveness of the proposed scheme.

关键词： passivity-based synchronization linear matrix inequality (LMI) chaotic systems Lyapunov theory

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System Dynamic Modelling of Patient Flow and Transferral Problem in a Mixed Public-Private Healthcare System:A case Study of Hong kong SAR

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Journal of Systems Science and Systems Engineering 2020年第5期29卷 590-608页

作者： c.k.M.LEE W.c.TAI kam k.H.NG Department of Industrial and Systems Engineering The Hon g Kong Polytechnic UniversityHung HornHong Kong SARChina School of Mechanical and Aerospace Engineering Nanyang Technological University50 Nanyang AvenueSingapore 639798Singapore

The current healthcare system in Hong kong is experiencing pressure due to constrained resources,with dramatic increases in inpatient services queue lengths,dissatisfaction with the working environment,unacceptable workforce arrangements and high turnover rate of hospital *** maintain the robustness of the healthcare system and a sustainable inpatients flow,the Food and Health Bureau launched a public-private partnership programme to utilise the resources of the public and private *** research investigates the potential for extension of the programme and further enhancing the sustainability of the long-term inpatient services under a mixed public-private healthcare policy via system dynamic *** findings show that an increase of human resources in public hospitals does not substantially improve inpatient flow rate ***,the results from the system dynamic approach provide insights into the expansion of the service areas of the programme and suggest increasing the number of referrals to private hospitals.

关键词： System dynamic models scenario analysis inpatient transferral mixed public-private healthcare system

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