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Cortical thickness abnormalities in patients with first episode psychosis:a meta-analysis of psychoradiologic studies and replication in an independent sample

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Psychoradiology 2021年第4期1卷 185-198页

作者： Keren Wen Youjin Zhao Qiyong Gong Ziyu Zhu Qian Li Nanfang Pan Shiqin Fu joaquim Radua Eduard Vieta Poornima Kumar Graham J.Kemp Bharat B.Biswal Huaxi MR Research Center(HMRRC) Department of RadiologyWest China Hospital of Sichuan UniversityChengdu 610041SichuanChina Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengdu 610041SichuanChina Functional and Molecular Imaging Key Laboratory of Sichuan Province Chengdu 610041SichuanChina Institut d’Investigacions Biom`ediques August Pi i Sunyer(IDIBAPS) Mental Health Research Networking Center(CIBERSAM)Barcelona 08036CataloniaSpain Centre for Psychiatric Research and Education Department of Clinical NeuroscienceKarolinska InstitutetSolna 171-77StockholmSweden Department of Psychosis Studies Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon WC2R 2LSUK Barcelona Bipolar Disorders and Depressive Unit Hospital ClinicInstitute of NeurosciencesUniversity of BarcelonaBarcelona 08036CataloniaSpain Center for Depression Anxiety and Stress ResearchMcLean HospitalBelmont 02478MAUSA Department of Psychiatry Harvard Medical SchoolBoston 02115MAUSA Liverpool Magnetic Resonance Imaging Centre(LiMRIC)and Institute of Life Course and Medical Sciences University of LiverpoolLiverpool L693GEUK Department of Biomedical Engineering New Jersey Institute of TechnologyNewark 07102NJUSA The Clinical Hospital of Chengdu Brain Science Institute MOE Key Laboratory for NeuroinformationUniversity of Electronic Science and Technology of ChinaChengdu 610054SichuanChina

Background:Abnormalities of cortical thickness(CTh)in patients with their first episode psychosis(FEP)have been frequently reported,but findings are ***:To define the most consistent CTh changes in patients with FEP by meta-analysis of publishedwholebrain ***:The meta-analysis used seed-based dmapping(SDM)software to obtain the most prominent regional CTh changes in FEP,and meta-regression analyses to explore the effects of demographics and clinical *** meta-analysis results were verified in an independent sample of 142 FEP patients and 142 age-and sex-matched healthy controls(HCs),using both a vertex-wise and a region of interest analysis,with multiple comparisons ***:The meta-analysis identified lower CTh in the rightmiddle temporal cortex(MTC)extending to superior temporal cortex(STC),insula,and anterior cingulate cortex(ACC)in FEP compared with *** significant correlations were identified between CTh alterations and demographic or clinical *** results were replicated in the independent dataset ***:This study identifies a robust pattern of cortical abnormalities in FEP and extends understanding of gray matter abnormalities and pathological mechanisms in FEP.

关键词： psychoradiology first episode psychosis early psychosis cortical thickness meta-analysis seed-based d mapping

Land Surface Displacement Geohazards Monitoring Using Multi-temporal InSAR Techniques

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Journal of Geodesy and Geoinformation Science 2021年第1期4卷 77-87页

作者： Guang LIU Perski ZBIGNIEW Salvi STEFANO Thiebes BENNI Lixin WU Jinghui FAN Shibiao BAI Lianhuan WEI Shiyong YAN Rui SONG Bignami CHRISTIAN Tolomei CRISTIANO Stefan SCHNEIDERBAUER Joao Sousa joaquim 无 Key Laboratory of Digital Earth Science Institute of Remote Sensing and Digital EarthChinese Academy of SciencesBeijing 100094China Carpathian Branch Polish Geological Institute-National Research InstituteCracow 31-560Poland National Institute of Geophysics and Volcanology Roma 605-00143Italy German Committee for Disaster Reduction Bonn 1353113Germany School of Resources and Civil Engineering Northeastern UniversityShenyang 110819China Division of Remote Sensing for Environment China Aero Geophysical Survey&Remote Sensing Center for Natural ResourcesBeijing 100083China School of Marine Science and Ocean Engineering Nanjing Normal UniversityNanjing 210046China School of Environment Science and Spatial Informatics China University of Mining and TechnologyXuzhou 221116China Mullard Space Science Laboratory Department of Space and Climate Physics University College London Holmbury RH56NTUK Eurac Research Bolzano 39100Italy School of Science and Technology University of Trás-os-Montes e Alto DouroVila Real 5000-801Portugal Centre for Robotics in Industry and Intelligent Systems(CRIIS) INESC Technology and Science(INESC-TEC)Porto 4200-465Portugal

China has been affected by some of the world’s most serious geological disasters and experiences high economic damage every *** occur not only in remote areas but also in highly populated *** the framework of the Dragon-432365 Project,this paper presents the main results and the major conclusions derived from an extensive exploitation of Sentinel-1,ALOS-2(Advanced Land Observing Satellite 2),GF-3(Gao Fen Satellite 3),and latest launched SAR(Synthetic Aperture Radar),together with methods that allow the evaluation of their importance for various ***,in the scope of this project,the great benefits of recent remote sensing data(wide spatial and temporal coverage)that allow a detailed reconstruction of past displacement events and to monitor currently occurring phenomena are exploited to study different areas and geohazards problems,including:surface deformation of mountain slopes;identification and monitoring of ground movements and subsidence;landslides;ground fissure;and building inclination *** movements detected in the different study areas were cross validated with different SAR sensors and truth data.

关键词： Dragon-4 project Sentinel-1 GF-3 landslide geohazards InSAR

Cardiac Complications in Maroteaux-Lamy Syndrome： Case Report

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Journal of Pharmacy and Pharmacology 2018年第4期6卷 410-414页

作者： Ricardo Siqueira Gongalves Claudia Aparecida Marques Landim Jesuita Mendes Cornelio joaquim Tomaz da Silva Graduating in Medicine. Universidade do Estado de Mato Grosso--UNEMAT Liga Academica de Cardiologia e Cirurgia Department of Cardiology and Intensive Medicine--Universidade do Estado de Mato Grosso--UNEMAT Liga Academica de Cardiologia e Cirurgia Cardiovascular (LACCIC) Caceres--MT 78200-000 Brazil Department of Pediatric Nursing--Hospital Municipal de Unai-MG (HMU) Unai-MG 38610-000 Brazil Department of General Surgery~Hospital Municipal de Unai-MG (HMU) Unai--MG 38610-000 Brazil

MLS （Maroteaux-Lamy syndrome） or MPS VI （mucopolysaccharidosis VI） is an autosomal recessive pathology in which there is absence or low activity of the enzyme N-Acetylgalactosamine-4-Sulfatase, which hydrolyzes GAGs （glycosaminoglycans） in the body （mainly dermatan sulfate）. Consequently, there occurs lysosomal deposition of GAGs in connective tissue multisystemic. Myocardium and heart valves are frequently affected structures, presenting a direct correlation with the reports of complications and deaths. Case report： RGS, male, 3 years and 2 months, diagnosed with MPS VI from the first month of life, in weekly ERT （enzyme replacement therapy） since 4 months of age （inconstant）. At physical examination： normotensive, with holosystolic heart murmur 3＋/6＋ in mitral focus. Complementary tests： normal electrocardiogram, echocardiogram with pronounced mitral regurgitation, concentric left ventricular hypertrophy of moderate degree and mild aortic insufficiency. Discussion： Mitral valve disease is common in patients with MLS. Conditions such as cardiomyopathy, fibroelastosis, aneurysm and pulmonary hypertension may occur in these patients, indicative of morbidity and mortality. Early and constant ERT may be useful in slowing a progression of heart disease. Conclusions： follow-up with a cardiologist is important to evaluate the progression of cardiac complications in MPS VI. Constant and early ERT provides better prognosis for these patients.

关键词： Mucopolysaccharidosis VI N-acetylgalactosamine-4-sulfatase mitral valve insufficiency enzyme replacement therapy.

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华金·詹乔和特累莎·倍拉乔访谈

艺术界 2005年第6期 62-67页

作者： joaquim Chancho Teresa Blanch 张俊中国美术学院附属中学教师

特累莎(下文用“TB”): 在新的技术条件下,你对绘画的当前境遇做了些什么? 詹乔(下文用“CH”): 绘画已丧失了几个世纪以来一直享有的特权,现在它必须同其余的创造性学科一起生存。目前的艺术中心将各种各样同艺术有关的的表现... 详细信息

特累莎(下文用“TB”): 在新的技术条件下,你对绘画的当前境遇做了些什么? 詹乔(下文用“CH”): 绘画已丧失了几个世纪以来一直享有的特权,现在它必须同其余的创造性学科一起生存。目前的艺术中心将各种各样同艺术有关的的表现形式、各种意图统统摆在一起。

关键词：绘画作品工作室卡拉瓦乔艺术家维米尔节奏感马蒂斯交叉线颜料几何形式

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猪圆环病毒病

国外畜牧学（猪与禽） 2009年第5期29卷 1-9页

作者：李政萍 joaquim Segalés

1猪圆环病毒病的历史及其争议知道如何去检测新的疾病吗？需要多久才能清楚知道与正在处理的新疾病有关的情况？这些问题并不容易回答。1997年流行的猪瘟在许多兽医看来是一个“新”的疾病；缺乏实际经验意味着，当其以一个新的面容出... 详细信息

1猪圆环病毒病的历史及其争议知道如何去检测新的疾病吗？需要多久才能清楚知道与正在处理的新疾病有关的情况？这些问题并不容易回答。1997年流行的猪瘟在许多兽医看来是一个“新”的疾病；缺乏实际经验意味着，当其以一个新的面容出现时，尽管它可能有着众所周知的了解基础，但还是需要花费大量的时间才能得到确诊。

关键词：猪圆环病毒病疾病兽医猪瘟确诊

Adolescent suicide behavior risk factors

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Adolescent suicide behavior risk factors

仔猪接种猪圆环病毒Ⅱ型疫苗时体内母源抗体水平的重要性

第十九届世界儿童及青少年精神卫生与相关学科学术会议

作者： joaquim Punti Elena Pujals Jordi Torralba Eloisa Arias Jezabel Palomino Pamias Montserrat Hospital Parc Tauli

＜正＞Background Suicide is actually the third leading cause of death in adolescents（Centers for Disease Control and Prevention,2008）.It is known that a prior suicide attempt is the single most important risk factor for completed suicide（Gould et al,2009）.Comorbidity is found in approximately 90%of all youths who commit suicide（Fleischmann et al,2005）,being most commonly associated substance use disorder and mood-related disorder（depression,bipolar disorder）.Other risk factors described in the literature include age,sex,ethnicity,cognitive profile

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国外畜牧学（猪与禽） 2012年第1期32卷 46-47页

作者：李红 joaquim Segalés

本文主要介绍了猪圆环病毒相关病(PCVAD)的许多最新研究进展,尤其从实践的角度阐述了PCVAD的病原学、发病机理、流行病学、诊断、治疗和预防。

关键词：猪圆环病毒Ⅱ型免疫系统病原学

欧洲鼻科专家就鼻-鼻窦炎和鼻息肉问题达成一致

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欧洲鼻科专家就鼻-鼻窦炎和鼻息肉问题达成一致

基于2002-2018年MODIS数据的黄海叶绿素a时空变化研究

第三届北京国际鼻-颅底外科技术及鼻变态反应研讨会

作者： joaquim Mullol MD PhD Rhinology Unit ENT DepartmentHospital Clinic de Barcelona Clinical and Experimental Respiratory ImmunoalergyIDIBAPS 巴塞罗那加泰罗尼亚西班牙欧洲著名的鼻科学专家欧洲过敏哮喘及临床免疫学会（EAACI）美国过敏哮喘及免疫学会会员（AAAAI）

＜正＞鼻-鼻窦炎是危害健康的一类严重问题,一般人群中约10％的个体受其困扰。由之而来的是可观的直接医疗成本、一般生活质量受到严重影响、下呼吸道疾病的发病增高。近年来,鼻科学者对鼻腔和鼻窦炎症的定义和分类已付出了许多努力。...

＜正＞鼻-鼻窦炎是危害健康的一类严重问题,一般人群中约10％的个体受其困扰。由之而来的是可观的直接医疗成本、一般生活质量受到严重影响、下呼吸道疾病的发病增高。近年来,鼻科学者对鼻腔和鼻窦炎症的定义和分类已付出了许多努力。由于鼻炎和鼻窦炎在解剖关系和病理生理方

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海洋通报 2020年第1期39卷 101-110页

作者：田洪阵刘沁萍 joaquim I.Goes Helga do Rosario Gomes 杨萌萌天津工业大学经济与管理学院天津300387 哥伦比亚大学拉蒙特多尔蒂地球观测站美国纽约10964 名古屋大学环境学研究生院日本爱知4648601

浮游植物作为食物链的基础,对海洋生态系统具有重要影响。黄海作为我国重要的渔场,渔业资源面临枯竭的危险,因此对该区浮游植物进行研究具有重要意义。叶绿素a浓度是反映浮游植物生物量的重要指标。利用谷歌地球引擎平台对2002-2018年的... 详细信息

浮游植物作为食物链的基础,对海洋生态系统具有重要影响。黄海作为我国重要的渔场,渔业资源面临枯竭的危险,因此对该区浮游植物进行研究具有重要意义。叶绿素a浓度是反映浮游植物生物量的重要指标。利用谷歌地球引擎平台对2002-2018年的MODIS Aqua叶绿素a浓度数据进行处理,并研究其时空分布与变化特征,然后结合区域气候、水文与地理特征以及海洋表面温度、风速、盐度、光合有效辐射和混合层厚度数据分析了其分布与变化的原因。研究发现:受陆源营养物质输入、近岸上升流以及黄海中央冷水团影响,叶绿素a浓度分布呈现由近岸向黄海中部递减特征;在季风、气候、水文的控制下,受风速、海洋表面温度、光合有效辐射、中央冷水团的影响,叶绿素a浓度的最大值出现在4月份,而最小值出现在6、7月份;受苏北沿岸海域海水污染和水体富营养化影响,沿岸海域盐度明显增加,海州湾叶绿素a浓度增速较大;影响黄海叶绿素a浓度变化的环境因子较复杂,除了部分月份存在显著的相关影响因子外,在全年和各季中不存在主导影响因子。

关键词：叶绿素a浓度 MODIS Aqua 谷歌地球引擎黄海