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Role of dynamic computed tomography scans in patients with congenital craniovertebral junction malformations

World Journal of Orthopedics 2017年第3期8卷 271-277页

作者： Otávio Turolo da Silva Enrico Ghizoni Helder Tedeschi Andrei Fernandes joaquim Department of Neurology Division of Neurosurgical State University of Campinas

AIM To evaluate the role of dynamic computed tomography(CT)scan imaging in diagnosing craniovertebral junction(CVJ)instability in patients with congenital CVJ *** Patients with symptomatic congenital CVJ malformations who underwent posterior fossa decompression and had a preoperative dynamic CT scan in flexion and extended position were included in this *** of the following craniometrical parameters were taken in flexed and extended neck position:Atlanto-dental interval(ADI),distance of the odontoid tip to the Chamberlain’s line,and the clivus-canal angle(CCA).Assessment of the facet joints congruence was also performed in both *** of the values obtained in flexion and extension were compared using a paired Student’s *** A total of ten patients with a mean age of 37.9 years were *** flexion imaging,the mean ADI was1.76 mm,the mean CCA was 125.4°and the mean distance of the odontoid tip to the Chamberlain’s line was+9.62 *** extension,the mean ADI was1.46 mm(P=0.29),the mean CCA was 142.2°(P<0.01)and the mean distance of the odontoid tip to the Chamberlain’s line was+7.11 mm(P<0.05).Four patients(40%)had facetary subluxation demonstrated in dynamic imaging,two of them with mobile subluxation(both underwent CVJ fixation).The other two patients with a fixed subluxation were not initially *** patient with atlantoaxial assimilation and C23 fusion without initial facet subluxation developed a latter CVJ instability diagnosed with a dynamic CT *** with basilar invagination had a lower CCA variation compared to the whole *** Craniometrical parameters,as well as the visualization of the facets location,may change significantly according to the neck *** imaging can provide additional useful information to the diagnosis of CVJ *** studies addressing the relationship between craniometrical changes and neck position are necessary.

关键词： Craniovertebral junction Dynamic imaging Basilar invagination Chiari malformation Treatment

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Interdependency Between Sustainable Development and Economic Growth （Investment Attraction）： The Role of City＇s Governance, Branding and Monitoring Strategies

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Journal of Modern Accounting and Auditing 2011年第7期7卷 734-748页

作者： joaquim Pereira Antonio Azevedo University of Minho Braga Portugal

Sustainable development is now considered the only option for collective happiness. This paper aims to highlight the interdependent role of city governance, its quality of life and corporate sustainable development process. A place that is good to live in, means that it is good to inhabit, work at, study invest, and visit. Therefore, public policies makers should think about the role of city administration in order to provide a good environment for entrepreneurship and corporate sustainable development. Territories, regions, cities and firms, must know their capabilities and competencies and define a common vision of the future, taking into account the present and the context in which they operate. Being defined as the strategy based on the principles of collective efficiency and market orientation, the successful implementation of activities requires ＂an operational framework for monitoring, supported by mechanisms of interdepartmental cooperation, and performance measurement procedures based on indicators and monitoring progress＂（ENDS-2015, 2007）. This paper discusses the implementation of place marketing strategies and adoption, by the city governance, of the best practices of business management such as： balanced score card methodologies, leading to the enhancing of the wellness produced by cities; promoting productivity, innovation and rational use of resources; and developing competences and expertise in order to strength their competitive advantages and achieve the desired sustainable development.

关键词： sustainable development city governance place marketing entrepreneurship balanced scorecard

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Small Scale Refrigerators and Freezers： Thermal Improvements in the Envelope

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Journal of Environmental Science and Engineering(A) 2017年第1期6卷 1-14页

作者： Clito Afonso joaquim Gabriel Department Mechanical Eng Faculty of Engineering of Porto University Porto R. Dr. Roberto Frias 4200-465 Porto Portugal Centre for Renewable Energy Research-CIENER University of Porto R. Dr. Roberto Frias 4200-465 Porto Portugal INEGI R. Dr. Roberto Frias 4200-465 Porto Portugal

Like in other sectors of activity, the sustainability in refrigeration systems is a mandatory goal to achieve, namely at house holdings, bars and restaurants, where small-scale refrigerators and freezers are widely used. The aim of this work is to demonstrate experimentally, trough measurements carried out in these equipments, the improvement that can be achieved if several modifications are implemented in traditional household refrigeration systems. In addition, it was also simulated and analysed experimentally a slightly different equipment, a refrigeration system used for draught beverages. Both systems work on a single vapour compression refrigeration with R-134a as working fluid. In the end, by implemented the modifications tested in the virtual model, it was possible to improve their thermal behaviour, a decrease in electrical energy consumption, as well as, the associated CO2 emissions reduction can be attained. In this project, the CFD （Computational Fluid Dynamics） soffware--ANSYS Fluent was used to simulate the ambient temperature and velocity fields inside the refrigerator and in that way to validate the measured results.

关键词： Small scalerefrigerators/freezer thermal efficiency air infiltration sustainability CO2 emissions reduction.

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The Colourlessness of the Zener Diode

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Journal of Literature and Art Studies 2012年第4期2卷 501-505页

作者： joaquim Marcelino Santos Lusiada University Lisbon Portugal

This short paper is about art and science and the human struggle to figure out the world we live in. It is also about the imagination and human progress, rationality and subjectivity, as well as the development of devices to ascertain out accurate knowledge--and yet the imagination and forms of thought are themselves devices that are integral to mechanical inventions. At the core of the subject under discussion, the aesthetic can be found reasons for the existence of other phenomena, the rational and the sensitive, epistemology and phenomenology, fulfilling human pleasure and necessity, and moving forward a humanized cosmos. Somewhere seems to rise and grow afresh a precise image of what we actually are and it can be revealed simply by being in the world and experiencing it on the basis of the mind-body-worM or by extending human senses through technology.

关键词： colour colourlessness art science epistemology phenomenology

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No Effects of Meteorological Factors on the SARS-CoV-2 Infection Fatality Rate

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Biomedical and Environmental Sciences 2021年第11期34卷 871-880页

作者： SOLANES Aleix LAREDO Carlos GUASP Mar FULLANA Miquel Angel FORTEA Lydia GARCIA-OLIVE Ignasi SOLMI Marco SHIN Jae II URRA Xabier RADUA joaquim Institut d'lnvestigacions Biomediques August Pi i Sunyer(IDIBAPS) BarcelonaSpain Department of Psychiatry and Forensic Medicine Autonomous University of BarcelonaBarcelonaSpain Neurosciences Unit Hospital ClinicBarcelonaSpain Adult Psychiatry and Psychology Department Institute of NeurosciencesHospital ClinicBarcelonaSpain Biomedical Network Research Centre on Mental Health(CIBERSAM) Instituto de Salud Carlos IIIMadridSpain Department of Medicine University of BarcelonaBarcelonaSpain Department of Medicine Autonomous University of BarcelonaBarcelonaSpain Pneumology Department Hospital Germans Trias i PujolBadalonaSpain Neurosciences Department University of PaduaPaduaItaly Padua Neuroscience Center PaduaItaly Department of Psychosis Studies Institute of PsychiatryPsychology and NeuroscienceKing's College LondonLondonUK Department of Pediatrics College of MedicineYonsei UniversitySeoul 03722Korea Centre for Psychiatric Research and Education Department of Clinical NeuroscienceKarolinska InstitutetStockholmSweden

Objective Previous studies have shown that meteorological factors may increase COVID-19 mortality,likely due to the increased transmission of the ***,this could also be related to an increased infection fatality rate(IFR).We investigated the association between meteorological factors(temperature,humidity,solar irradiance,pressure,wind,precipitation,cloud coverage)and IFR across Spanish provinces(n=52)during the first wave of the pandemic(weeks 10–16 of 2020).Methods We estimated IFR as excess deaths(the gap between observed and expected deaths,considering COVID-19-unrelated deaths prevented by lockdown measures)divided by the number of infections(SARS-CoV-2 seropositive individuals plus excess deaths)and conducted Spearman correlations between meteorological factors and IFR across the *** We estimated 2,418,250 infections and 43,237 *** IFR was 0.03%in<50-year-old,0.22%in 50–59-year-old,0.9%in 60–69-year-old,3.3%in 70–79-year-old,12.6%in 80–89-year-old,and26.5%in≥*** did not find statistically significant relationships between meteorological factors and adjusted ***,we found strong relationships between low temperature and unadjusted IFR,likely due to Spain’s colder provinces’aging *** The association between meteorological factors and adjusted COVID-19 IFR is *** age differences or ignoring COVID-19-unrelated deaths may severely bias COVID-19 epidemiological analyses.

关键词： Climate COVID-19 Infection fatality rate SARS-CoV-2 Temperature Weather

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Comparison of the patient and partner satisfaction with 700CX and Titan penile prostheses

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Asian Journal of Andrology 2017年第3期19卷 321-325页

作者： Javier Romero Otero Cesar Rojas Cruz Borja Garcia Gomez joaquim Sarquella Geli lose Medina Polo Eduard Ruiz Castane Alfredo Rodriguez Antolin 12 de Octubre University Hospital Department of Urology Madrid Spain Fundacio Puigvert Department of Andrology Barcelona Spain.

Most widespread three-component penile prosthesis models are 700CXTM and Titan~. Our purpose is to assess patient and partner satisfaction after the first implant. This is a multicenter, retrospective, nonrandomized study in which all patients who met the inclusion criteria between 2009 and 2013 were included. In total, 248 patients agreed to participate. To evaluate patient satisfaction, a validated but modified 11-question questionnaire was completed （EDITS）; and a nonvalidated two-item questionnaire was given to the partner. Statistical analysis used an ordinal logistic regression model. Two hundred and forty-eight patients （194 with 700CXTM vs 54 with Titan） and 207 couples completed the questionnaire （165 with 700CXTM vs 42 with Titan）. Overall satisfaction was high. Both showed great reliability for sexual intercourse and high compliance with prior expectations. Most patients were able to manage the penile prosthesis correctly within 6 months. Postoperative penile shortening led to some dissatisfaction in 42% and 46% of cases （700CX/Titan）. Significant differences were found in three questions of patients＇ questionnaire. There were more patients satisfied with the 700CXTM （P= 0.0001）. No patient with Titan implant took longer than 6 months to optimal management. Only 4% of patients with 700CXTM implant were dissatisfied with the deflation, in contrast to 24% with the Titan （P = 0.0031）. Of the two partners＇ questions, one showed a statistically significant difference （P = 0.0026）. It seems that group 700CX＂ would recommend to re-implant the prosthesis with a greater tendency. The overall satisfaction was very high for both prostheses. The final aspect of the erected and flaccid penis was satisfactory, but both groups showed significant discontent with its final size. Partners＇ overall satisfaction was high.

关键词： erectile dysfunction penile implantation penile prosthesis

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The European Animal Feeding without Antibiotics Growth Promoters（AGP）;New Model,Challenge and Opportunities

The European Animal Feeding without Antibiotics Growth Promo...

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第二届全国家禽营养与饲料科技研讨会

作者： joaquim Brufau I RTA Mas de BoverCtra.Reus-Morell Km 3.843120 ConstantiTarragonaSpain

＜正＞This paper will try to explain why and how the EU is dealing with the current ban of Antibiotics Growth Promoters （AGP） in animal feeding;subjects like that is considered a sector strategies applied to recover the consumer’s confidence. The sector is also wondering if the recently crisis on food safety （opportunity） may produce a new model for European ani- mal ***,the current farming system will be discussed.

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Indirect printing of hierarchical patient-specific scaffolds for meniscus tissue engineering

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Bio-Design and Manufacturing 2019年第4期2卷 225-241页

作者： Joao BCosta Joana Silva-Correia Sandra Pina Alain da Silva Morais Sílvia Vieira Hélder Pereira Joao Espregueira-Mendes Rui LReis joaquim M.Oliveira B′s Research Group I3Bs-Research Institute on BiomaterialsBiodegradables and BiomimeticsUniversity of MinhoHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineAveParkZona Industrial da Gandra4805-017 Barco GmrPortugal ICVS/3B’s-PT Government Associate Laboratory Braga/GuimaraesPortugal The Discoveries Centre for Regenerative and Precision Medicine Headquarters at University of MinhoAvepark4805-017 BarcoGuimar'sPortugal Ripoll y De Prado Sports Clinic:Murcia-Madrid FIFA Medical Centre of Excellence MurciaSpain Orthopedic Department Centro Hospitalar Póvoa de Varzim Vila do CondePortugal Clínica do Dragao Espregueira-Mendes Sports CentreFIFA Medical Centre of ExcellencePortoPortugal Dom Henrique Research Centre PortoPortugal Orthopedic Department University of MinhoBragaPortugal

The complex meniscus tissue plays a critical role in the knee. The high susceptibility to injury has led to an intense pursuit for better tissue engineering regenerative strategies, where scaffolds play a major role. In this study, indirect printed hierarchical multilayered sca ffolds composed by a silk fibroin (SF) upper layer and an 80/20 (w/w) ratio of SF/ionic-doped β-tricalcium phosphate (TCP) bottom layer were developed. Furthermore, a comparative analysis between two types of sca ffolds pro- duced using di fferent SF concentrations, i.e., 8% (w/v) (Hi8) and 16% (w/v) (Hi16) was performed. In terms of architecture and morphology, the produced sca ffolds presented homogeneous porosity in both layers and no di fferences were observed when comparing both sca ffolds. A decrease in terms of mechanical performance of the sca ffolds was observed when SF concentration decreased from 16 to 8% (w/v). Hi16 revealed a static compressive modulus of 0.66 ± 0.05 MPa and dynamical mechanical properties ranging from 2.17 ± 0.25 to 3.19 ± 0.38 MPa. By its turn, Hi8 presented a compressive modulus of 0.27 ± 0.08 MPa and dynamical mechanical properties ranging from 1.03 ± 0.08 MPa to 1.56 ± 0.13 MPa. In vitro bioactivity studies showed formation of apatite crystals onto the surface of Hi8 and Hi16 bottom layers. Human meniscus cells (hMCs) and human primary osteoblasts were cultured separately onto the top layer (SF8 and SF16) and bottom layer (SF8/TCP and SF16/TCP) of the hierarchical sca ffolds Hi8 and Hi16, respectively. Both cell types showed good adhesion and proliferation as denoted by the live/dead staining, Alamar Blue assay and DNA quanti fication analysis. Subcutaneous implantation in mice revealed weak in flammation and sca ffold’s integrity. The hierarchical indirect printed SF sca ffolds can be promising candidate for meniscus TE sca ffolding applications due their suitable mechanical properties, good biological performance and possibility of being applied in a patie

关键词： Patient-specific Indirect printing Hierarchical Silk fibroin Enzymatic-cross-linking Meniscus

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与Biot S波有关的旋度场

与Biot S波有关的旋度场

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美国勘探地球物理学家学会第61届年会

作者： joaquim X. C. neto 孙忠勤 Institute de Geociencias PPPG/Univ.Federal da Bahia

本文应用孔隙弹性的Biot理论（Biot,1956a,b）和线性粘滞动力学算子（Norris, 1989）来研究与Biot介质中的S波有关的固体运动和流体位移之间的耦合。固体部分的剪切位移以某种复合方式传给流体,这种运动在Biot单位体积内不同相。耦合运...

本文应用孔隙弹性的Biot理论（Biot,1956a,b）和线性粘滞动力学算子（Norris, 1989）来研究与Biot介质中的S波有关的固体运动和流体位移之间的耦合。固体部分的剪切位移以某种复合方式传给流体,这种运动在Biot单位体积内不同相。耦合运动的振幅取决于岩石物性参数和波的方向。耦合方程的平面波解显示出影响复合介质中耦合波传播的主要因素。衰减和相速度都受到孔隙系统性质的影响,并与频率有关。对第二类P波来说,高值的品质因数与Geertsma 和Smit（1961）所发现的一样。它表明,与耦合运动性质有关的旋转像扩散波。

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Ten-year experience with penile prosthetic surgery for the treatment of erectile dysfunction:outcomes of a tertiary referral center and predictors of early prosthetic infection

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Asian Journal of Andrology 2022年第1期24卷 32-39页

作者： Franco Palmisano Luca Boeri Riccardo Ievoli Josvany Sánchez-Curbelo Matteo Giulio Spinelli Andrea Gregori Antonio Maria Granata Eduard Ruiz-Castane Emanuele Montanari joaquim Sarquella-Geli ASST Fatebenefratelli-Sacco Department of UrologyLuigi Sacco University HospitalMilan 20157Italy IRCCS Foundation Ca’Granda Ospedale Maggiore Policlinico Department of UrologyUniversity of MilanMilan 20122Italy Department of Economics and Management University of FerraraFerrara 44121Italy FundacióPuigvert Department of AndrologyUniversity of BarcelonaBarcelona 08025Spain

We aimed to evaluate ten-year outcomes of penile prosthesis(PP)implantation for the treatment of erectile dysfunction and to assess predictors of early prosthetic infection(EPI).We identified 549 men who underwent 576 PP placements between 2008 and *** and multivariate analyses were used to identify potential predictors of *** EPI predictive nomogram was ***-five(6.1%)cases of EPI were recorded with an explant rate of 3.1%.In terms of satisfaction,82.0%of the patients defined themselves as“satisfied,”while partner’s satisfaction was 88.3%.Diabetes(P=0.012),longer operative time(P=0.032),and reinterventions(P=0.048)were associated with EPI risk,while postoperative ciprofloxacin was inversely associated with EPI(P=0.014).Rifampin/gentamicin-coated 3-piece inflatable PP(r/g-c 3IPP)showed a higher EPI risk(P=0.019).Multivariate analyses showed a two-fold higher risk of EPI in diabetic patients,redo surgeries,or when a r/g-c 3IPP was used(all P<0.03).We showed that diabetes,longer operative time,and secondary surgeries were the risk factors for *** ciprofloxacin was associated with a reduced risk of EPI,while r/g-c 3IPP had higher EPI rates without an increased risk of PP *** further validation,the proposed nomogram could be a useful tool for the preoperative counseling of PP implantation.

关键词： Boston Coloplast Titan three-piece penile prosthesis erectile dysfunction impotence Inhibizone patient satisfaction penile prosthesis prosthesis infection rifampin soaking

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