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国外畜牧学（猪与禽） 2000年第6期20卷 50-52页

作者：袁森泉林颖 joaquim Segales 西班牙巴塞罗那自治大学解剖病理教研室

Antithrombotic treatment in chronic heart failure and sinus rhythm: Systematic review

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World Journal of Meta-Analysis 2015年第1期3卷 36-42页

作者： Daniel Caldeira Inês Cruz Rita Calé Cristina Martins Helder Pereira joaquim J Ferreira Fausto J Pinto Joo Costa Cardiology Department Hospital Garcia de Orta Clinical Pharmacology Unit Instituto de Medicina Molecular Laboratory of Clinical Pharmacology Faculty of MedicineUniversity of Lisbon Cardiology Department CCUL CAML Faculty of Medicine Evidence Based Medicine Centre Faculty of Medicine University of Lisbon Portuguese Collaborating Centre of the Cochrane Iberoamerican Network Faculty of Medicine University of Lisbon

AIM: To assess the efficacy and safety of antithrombotic drugs(antiplatelet or anticoagulant drugs) compared to no antithrombotic treatment or placebo in patients with heart failure(HF) and sinus rhythm. METHODS: We searched Medline and Cochrane Library for randomized controlled trials evaluating antithrombotic treatment and no antithrombotic treatment in patients with HF and sinus rhythm. Risk ratio(RR) and 95%CIs were estimated performing meta-analysis with random effects method. RESULTS: Two studies met the inclusion criteria: Heart failure Long-term Antithrombotic Study and Warfarin/Aspirin Study in Heart failure, with 336 patients and mean follow-up 1.8-2.25 years. Stroke risk was not reduced by acetylsalicylic acid(RR = 1.18, 95%CI: 0.17-8.15), oral anticoagulation(RR = 0.30, 95%CI: 0.03-2.65) or overall antithrombotic drugs(RR = 0.52, 95%CI: 0.10-2.74). Acetylsalicylic acid showed a significant increased risk of worsening HF(RR = 1.78, 95%CI: 1.08-2.92), while oral anticoagulation had no impact in this outcome(RR = 1.03, 95%CI: 0.61-1.75). Overall antithrombotic drugs showed a significant risk increase of major bleeding(RR = 6.99, 95%CI: 0.89-54.64). CONCLUSION: Best available evidence does not support the routine use of antithrombotic drugs in patients with HF and sinus rhythm. These drugs, particularly oral anti-coagulation has the hazard of increase significantly major bleeding risk.

关键词： Heart failure Sinus rhythm Platelet aggregation inhibitors Anticoagulants

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针灸配合中成药治疗登革热临床分析

实用中医药杂志 2008年第9期24卷 553-554页

作者：李杜非 Filomeno joaquim da Saldanha 成都市温江区中医医院四川成都611130 东帝汶GUIDO VALADARES国家医院

目的:观察针灸配合中成药治疗登革热的临床疗效。方法:将126例分为两组,观察组64例用针灸、拔罐配合板蓝根冲剂、Vc银翘片和云南白药治疗;西药组62例高热时采用物理降温,必要时使用退热药,如高热不退可短期应用肾上腺皮质激素,有出血倾... 详细信息

目的:观察针灸配合中成药治疗登革热的临床疗效。方法:将126例分为两组,观察组64例用针灸、拔罐配合板蓝根冲剂、Vc银翘片和云南白药治疗;西药组62例高热时采用物理降温,必要时使用退热药,如高热不退可短期应用肾上腺皮质激素,有出血倾向者加止血药。治疗2周后进行疗效观察。结果:白细胞、血小板恢复正常时间治疗组为(6.5±0.77)天、对照组为(7.48±0.89)天。治疗组、对照组三期持续时间分别为(2.12±1.17)天、(2.13±1.11)天、(4.12±1.18)天和(3.11±1.16)天、(3.16±1.18)天、(5.19±2.14)天。两组比较差异有非常显著性意义(P<0.01)。结论:针灸配合中成药治疗登革热能促进白细胞、血小板的更快恢复正常,缩短发热期、出疹期、恢复期各期持续时间,其疗效明显优于西药对症支持治疗。

关键词：登革热针灸疗法中成药对照治疗

Influence of a nucleotide oligomerization domain 1 (NOD1) polymorphism and NOD2 mutant alleles on Crohn's disease phenotype

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World Journal of Gastroenterology 2007年第41期13卷 5446-5453页

作者： Elisabet Cantó Elena Ricart David Busquets David Monfort Esther García-Planella Dolors González joaquim Balanzó José L Rodríguez-Sánchez Sílvia Vidal Department of Immunology Sant Pau Hospital & Research Inst.Sant Pau HospitalBarcelona 08025Spain Department of Gastroenterology CIBER-EHD.Clinic HospitalBarcelona-08025Spain Department of Digestive Pathology Sant Pau HospitalBarcelona 08025Spain

AIM： To examine genetic variation of nucleotide oligomerization domain 1 （NOD/） and NOD2, their respective influences on Crohn＇s disease phenotype and gene-gene interactions. METHODS：（ND1＋32656＊1） NOD1 polymorphism and SNPS, SNP12 and SNP13 of NOD2 were analyzed in 97 patients and 50 controls. NOD2 variants were determined by reaction restriction fragment length polymorphism analysis. NOD1 genotyping and NOD2 variant confirmation were performed by specific amplification and sequencing. RESULTS： The distribution of NOD1 polymorphism in patients was different from controls （P = 0.045） and not altered by existence of NOD2 mutations. In this cohort, 30.92% patients and 6% controls carried at least one NOD2 variant （P 〈 0.001） with R702W being the most frequent variant. Presence of at least one NOD2 mutation was inversely associated with colon involvement （9.09% with colon vs 36.4% with ileal or ileocolonic involvement, P = 0.04） and indicative of risk of penetrating disease （52.63% with penetrating vs 25.64% with non-penetrating or stricturing behavior, P = 0.02）. L1007finsC and double NOD2 mutation conferred the highest risk for severity of disease （26.3% with penetrating disease vs 3.8% with non-penetrating or stricturing behavior presented L1007finsC, P = 0.01 and 21.0% with penetrating disease vs 2.5% with non-penentrating or stricturing behavior carried double NOD2 mutation, P = 0.007）. Exclusion of patients with NOD2 mutations from phenotype/NODl-genotype analysis revealed higher prevalence of ＊1＊1 genotype in groups of younger age at onset and colonic location.CONCLUSION： This study suggests population differences in the inheritance of risk NOD1 polymorphism and NOD2 mutations. Although no interaction between NOD1-NOD2 was noticed, a relationship between disease location and Nod-like receptor molecules was established.

关键词： Crohn's disease Nucleotide oligomerization domain 1 Nucleotide oligomerization domain 2

Effect of Freshwater Influx on Phytoplankton in the Mandovi Estuary (Goa, India) during Monsoon Season: Chemotaxonomy

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Journal of Water Resource and Protection 2013年第3期5卷 349-361页

作者： Sushma G. Parab S. G. Prabhu Matondkar Helga do R. Gomes joaquim I. Goes Lamont Doherty Earth Observatory at Columbia University New York USA National Institute of Oceanography Dona Paula Goa India

The Mandovi estuary is a prominent water body that runs along the west coast ofIndia. It forms an estuarine network with the adjacent Zuari estuary, connected via the Cumbharjua canal. The physico-chemical conditions seen in the Mandovi estuary are influenced by two factors: the fresh water runoff during the monsoon season (June-September) and the tidal influx of coastal seawater during the summer (October to May) season. However, the effects of monsoon related changes on the phytoplankton of the Mandovi estuary are not yet fully understood. An attempt to understand the same has been made here by applying the process of daily sampling at a fixed station throughout the monsoon season. It was noticed that the onset of the monsoon is responsible for an increase in nitrate levels upto 26 μM from a (chl a) as high as 14 μg·L-1 during the same period. The phytoplankton population was observed through both chemotaxonomy and microscopy and was found to be composed mainly of diatoms. CHEMTAX analysis further uncovers the presence of several other groups of phytoplankton, the presence of which is yet to be reported in many other tropical estuaries. It includes chrysophytes, cyanobacteria, prasinophytes, prymnesiophytes and chlorophytes. The appearance of phytoplankton groups at various stages of the monsoon was recorded, and this data is discussed in relation to environmental changes in the Mandovi estuary during the monsoon season.

关键词： Phytoplankton Pigment Analysis Monsoon Freshwater Runoff CHEMTAX

Implementation and Follow-Up of Medical Abortion in Catalonia (2010-2014)

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Open Journal of Obstetrics and Gynecology 2017年第2期7卷 208-219页

作者： Carme Ollé Roser Bosser Rosa Gispert Neus Prat Pilar Magrinyà Carme Coll Ramón Escuriet Ricard Tresserras joaquim Calaf Subdirectorate-General for the Service Porfofolio and Health Map Directorate-General for Health Planning Ministry of Health Barcelona Spain Studies Service Directorate-General for Health Planning Ministry of Health Barcelona Spain Sexual and Reproductive Health Services Directorate-General for Health Planning (ASSIR) Costa Ponent Barcelona Spain Directorate-General for Health Planning Ministry of Health Barcelona Spain Sexual and Reproductive Health Services Directorate-General for Health Planning (ASSIR) Barcelonès Nord i Maresme Barcelona Spain Chair of Obstetrics and Gynaecology Autonomous University of Barcelona Barcelona Spain

In 2011 a protocol for medical abortions (MA) up to 49 days of pregnancy was approved by the Ministry of Health of Catalonia’s autonomous government and it was progressively introduced through the public network of the Sexual and Reproductive Health Units (SRHU). In 2014, a new protocol extended to 63 days of pregnancy was set up. Data come from the official abortion registry held by the Ministry of Health, which collects statistical data from all abortions performed in Catalonia. Since 2011, the number and rate of abortions in Catalonia have decreased while the number of health centers providing abortions has increased, especially the SRHU. The proportion of MA abortions went from 0.4% (2010) to 36.9% (2014), while the percentage of early abortions (up to 7 weeks) surged by 14.7%. SRHU reported 73.4% of all MA and hospitals performed 18.7% of the total, while outpatient centers accounted for the remaining 7.9%. Compared to surgical abortions, women having had MA have higher levels of education and lower rates of unemployment. Furthermore, they have more living offspring and fewer previous terminations as well as more frequent attendance to a public family planning center.

关键词： Medical Abortion Catalonia Early Abortions Sexual and Reproductive Health Units (SRHU)

“猪Ⅱ型圆环病毒”专栏二:由猪圆环病毒引起的病毒血症对生产性能的影响

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国外畜牧学（猪与禽） 2013年第5期33卷 20-22页

作者：陶莉 Sergio Lopez Soria joaquim Segales

自1998年病毒血症与猪圆环病,现在也称作由PCV2引起的系统疾病（Systemic Disease due toPCV2,PCV2-SD）与联系起来后,与PCV2有关的病理学及其造成的养猪生产损失已成为研究的目标。自那时起，

关键词：猪圆环病毒病毒血症猪Ⅱ型圆环病毒生产性能 PCV2 生产损失病理学养猪

莫桑比克前总统希萨诺在中国非洲研究院成立大会上的致辞

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中国非洲学刊 2020年第1期1卷 16-19页

作者： joaquim Alberto Chissano 邓延庭(译) 不详中国非洲研究院

(2019年4月9日,北京)尊敬的中国共产党中央政治局委员、中国共产党中央外事工作委员会办公室主任杨洁篪阁下,中国社会科学院院长谢伏瞻阁下,中国非洲研究院国际顾问委员会成员们,来自中国和非洲智库学者的优秀代表们,大使阁下们以及外... 详细信息

(2019年4月9日,北京)尊敬的中国共产党中央政治局委员、中国共产党中央外事工作委员会办公室主任杨洁篪阁下,中国社会科学院院长谢伏瞻阁下,中国非洲研究院国际顾问委员会成员们,来自中国和非洲智库学者的优秀代表们,大使阁下们以及外交官们,尊敬的来宾们,女士们、先生们:我很荣幸能够参加这次活动。我认为,这是在悠久的中非关系史中具有里程碑意义的一件大事。

关键词：中国社会科学院外事工作谢伏瞻莫桑比克国际顾问中国和非洲办公室主任希萨诺

Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation

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World Journal of Gastroenterology 2021年第12期27卷 1161-1181页

作者： Karina Gordon Estela Regina Ramos Figueira Joel Avancini Rocha-Filho Luiz Antonio Mondadori Eduardo Henrique Giroud joaquim Joao Seda-Neto Eduardo Antunes da Fonseca Renata Pereira Sustovitch Pugliese Agustin Moscoso Vintimilla Jose Otavio Costa Auler Jr Maria Jose Carvalho Carmona Luiz Augusto Carneiro D'Alburquerque Division of Anesthesiology Hospital das ClínicasUniversity of São Paulo School of MedicineSão Paulo 05403-000Brazil Department of Anesthesiology AC Camargo Cancer CenterSão Paulo 01509-010Brazil Department of Gastroenterology Discipline of Liver and Gastrointestinal TransplantationLaboratory of Medical Investigations LIM37 Hospital das ClinicasUniversity of São Paulo School of MedicineSão Paulo 05402-000Brazil Department of Liver Transplantation AC Camargo Cancer CenterSão Paulo 01525-901Brazil Department of Gastroenterology Division of Liver and Gastrointestinal TransplantHospital das ClinicasUniversity of São Paulo School of MedicineSão Paulo 05402-000Brazil

BACKGROUND The impact of perioperative blood transfusion on short-and long-term outcomes in pediatric living donor liver transplantation(PLDLT)must still be ascertained,mainly among young *** and surgical postoperative complications related to perioperative blood transfusion are well described up to three months after adult liver *** To determine whether transfusion is associated with early and late postoperative complications and mortality in small patients undergoing *** We evaluated the effects of perioperative transfusion on postoperative complications in recipients up to 20 kg of body weight,submitted to PLDLT.A total of 240 patients were retrospectively allocated into two groups according to postoperative complications:Minor complications(n=109)and major complications(n=131).Multiple logistic regression analysis identified the volume of perioperative packed red blood cells(RBC)transfusion as the only independent risk factor for major postoperative *** receiver operating characteristic curve was drawn to identify the optimal volume of the perioperative RBC transfusion related to the presence of major postoperative complications,defining a cutoff point of 27.5 mL/***,patients were reallocated to a low-volume transfusion group(LTr;n=103,RBC≤27.5 mL/kg)and a high-volume transfusion group(HTr;n=137,RBC>27.5 mL/kg)so that the outcome could be *** High-volume transfusion was associated with an increased number of major complications and mortality during hospitalization up to a 10-year follow-up *** a short-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and bleeding complications,with a decrease in rejection complications compared to the *** a long-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and minor neoplastic complications,with a decrease in rejection ***,Cox hazard regr

关键词： Liver transplantation Child Blood transfusion Outcome Liver cirrhosis Mortality

Management Crop Production System: using Precision Farming concept for a decision making

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Management Crop Production System: using Precision Farming c...