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Heterosis effect for larval performance of fall armyworm interstrain hybrids

Insect Science 2024年第4期31卷 1296-1312页

作者： Laijiao Lan nicolas nègre DGIMI University of MontpellierINRAEMontpellierFrance

Spodoptera frugiperda,also known as fall armyworm(FAW),is an invasive crop pest that can feed on a variety of host plants,posing a serious threat to food *** are two sympatric strains of FAW that are morphologically identical but described with different food preferences:the“rice strain”(SfR)and the“corn strain”(SfC).A few genetic loci exist to identify these two *** and Z-chromosome-linked haplotypes are the most used,but the biggest part of the genome displays little polymorphism between strains that could explain their adaptation to different *** have previously observed consistent transcription differences between the strains in both laboratory and natural ***,we wonder if there are effects from host-strain-associated loci,maternally or paternally inherited,on FAW performance that could explain the divergence between the two FAW *** test this hypothesis,we first produced two F1 hybrid generations(SfR♀×SfC♂,SfC♀×SfR♂).These reciprocal hybrids should be heterozygous for all chromosomes except for the maternally inherited mitochondrial and sexual W *** evaluate whether plant preference is determined by these genetic loci,we cultivated the two hybrids and the two parental strains in triplicate on an artificial diet and recorded several phenotypic traits such as weight over time,survival rate,emerging rate,developmental time,and sex ***,the same performance experiment was carried out on corn ***,on the artificial diet,the two hybrid genotypes were both more performant than the two parental strains in terms of survival rate,pupal emerging rate,and developmental time,whereas they were intermediate to the inbred parental strains in pupal *** the corn plant diet,both hybrid genotypes outperformed the two parental strains in larval *** these asymmetrical results revealed that mitochondrial or sex-linked haplotypes alone cannot explain the performance differences

关键词： fall armyworm Haldane's rule heterosis hybrid performance mitochondria

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RBC aggregation,deformation and adhesion to endothelium:Role of nitric oxide derived from L-Arginine and sodium nitroprusside

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Journal of Innovative Optical Health Sciences 2024年第5期17卷 53-65页

作者： M.K.Maksimov P.B.Ermolinskiy O.n.Scheglovitova n.n.Sklyankina A.V.Muravyov A.E.Lugovtsov A.V.Priezzhev Faculty of Physics M.V.Lomonosov Moscow State University bld.1subbuilding.2Leninskie goryMoscow 11991Russia n.F.Gamaleya national Research Center for Epidemiology and Microbiology 18 Gamaleya StreetMoscow 123098Russia K.D.Ushinsky Yaroslavl State Pedagogical University 108/1 Respublikanskaya StreetYaroslavl 150000Russia

Red blood cells(RBCs)are the most abundant human blood *** aggregation and deformation strongly determine blood viscosity which impacts hemorheology and *** turn,RBC properties depend on di®erent endogenous and exogenous *** such factor is nitric oxide(nO),which is mainly produced by endothelial cells(EC)from L-arginine amino acid in the circulatory *** the mechanisms of the RBC-endothelium interplay are not clear up to date and considering its possible clinical importance,the aims of this study are to investigate in vitro:(1)The e®ect of L-arginine induced nO on RBC aggregation and adhesion to endothelium;(2)the nO e®ect on RBC aggregation and deformation induced by L-arginine and sodium nitroprusside without the presence of endothelium in the *** RBC aggregation and adhesion to a monolayer of EC were studied using optical tweezers(OT).The RBC deformability and aggregation without endothelium in the samples were studied using the°ow chamber method and Myrenne *** con¯rmed that nO increases deformability and decreases aggregation of *** showed that the soluble guanylate cyclase pathway appears to be the only nO signaling pathway *** the samples with the endothelium,the\bell-shaped"dependence of RBC aggregation force on L-arginine concentration was observed,which improves our knowledge about the process of nO production by ***,data related to L-arginine accumulation by endothelium were obtained:necessity of the presence of extracellular L-arginine stated by other authors was put under *** our study,nO decreased the RBC-endothelium adhesion,however,the tendency appeared to be weak and was not con¯rmed in another set of *** our knowledge,this is the¯rst attempt to measure the forces of RBC adhesion to endothelium monolayer with OT.

关键词： Red blood cells aggregation L-arginine endothelium optical tweezers Myrenne flow chamber

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A FLEXIBLE OBJECTIVE-COnSTRAInT APPROACH AnD A nEW ALGORITHM FOR COnSTRUCTInG THE PARETO FROnT OF MULTIOBJECTIVE OPTIMIZATIOn PROBLEMS

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Acta Mathematica Scientia 2024年第2期44卷 702-720页

作者： n.HOSEInPOOR M.GHAZnAVI Faculty of Mathematical Sciences Shahrood University of TechnologyShahroodIran

In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized problem extends the objective-constraint problem. It is demonstrated that how adding variables to the scalarized problem, can lead to find conditions for (weakly, properly) Pareto optimal solutions. Applying the obtained necessary and sufficient conditions, two algorithms for generating the Pareto front approximation of bi-objective and three-objective programming problems are designed. These algorithms are easy to implement and can achieve an even approximation of (weakly, properly) Pareto optimal solutions. These algorithms can be generalized for optimization problems with more than three criterion functions, too. The effectiveness and capability of the algorithms are demonstrated in test problems.

关键词： multiobjective optimization Pareto front scalarization objective-constraint approach proper efficient solution

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Proximity to corridors benefits bird communities in vegetated interrow vineyards in Mendoza, Argentina

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Avian Research 2024年第2期15卷 147-155页

作者： Andrea Paula Goijman Agustín Zarco EEA La Consulta Instituto Nacional de Tecnología Agropecuaria(INTA)San CarlosMendozaArgentina Instituto Argentino de Investigacion en las Zonas Aridas(IADIZA)COnICET 5500MendozaArgentina

Management under ecological schemes and increasing habitat heterogeneity,are essential for enhancing biodiversity in *** provide several contributions to agriculture,for example pest control,recreation and enhancing human mental health,and have intrinsic *** are also ideal model organisms because they are easy to survey,and species respond differently to agricultural land use at different *** borders of crops are key for many species of birds,and distance to the border have been found to be an important factor in vineyard-dominated *** evaluate if there are differences in the bird assemblage,between the interior compared to borders within vineyards,using a hierarchical community occupancy *** hypoth-esized that occupancy of birds is greater in environments with greater heterogeneity,which in this study was considered to be contributed by the proximity to vegetated *** expected that vineyard borders close to corridors will have higher bird occupancy than the center of the *** research was conducted in three vineyards with biodiversity-friendly management practices,in Gualtallary,Mendoza,*** surveys were conducted over three breeding seasons from 2018 to *** and richness of the bird community was more closely associated with the borders adjacent to the corridors than with the interior of the vineyards,as we initially predicted,although the assemblage of birds did not differ *** than 75%of the registered species consume exclusively or partially ***-friendly management and ecological schemes,together with vegetated corridors provide multiple benefits for biodiversity *** ap-proaches not only minimize the use of agrochemicals but also prioritize soil cover with spontaneous vegetation,which supports a diverse community of insectivorous bird species,potentially contributing to pest control.

关键词： Avian Bayesian analysis Field scale agroecosystem Management Multi-species occupancy model nature’s contributions to people

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Clinical profile and outcomes in very elderly patients with atrial fibrillation anticoagulated with rivaroxaban: data from the EMIR study

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Journal of Geriatric Cardiology 2024年第7期21卷 723-732页

作者： Francisco Marín Manuel Anguita Sánchez Iñaki Lekuona Marcelo Sanmartín Fernán-dez Vivencio Barrios Carlos Perez Muñoz Juan Cosín-Sales Alejandro IPérez Cabeza Vanesa Roldán Schilling Carles Rafols Priu Esteban Orenes-Piñero María Asunción Es-teve-Pastor Department of Cardiology Hospital Clínico Universitario Virgen de la ArrixacaIMIB-ArrixacaUniversity of MurciaCIBERCVMurciaSpain Department of Cardiology Hospital Reina Sofía CórdobaIMIBICUniversity of CordobaCIBERCVCórdobaSpain Hospital Galdakao-Usansolo BizkaiaSpain Department of Cardiology Hospital Uni-versitario Ramony CajalCIBERCVMadridSpain Department of Cardiology University Hospital Ramóny CajalAl-caláUniversityMadridSpain Medical Center La Capillita Sanlúcar de Barrameda.Private cardiology clinicJerez de la FronteraSpain Department of Cardiology Hospital Arnau de VilanovaValenciaSpain Department of Car-diology Virgen de la Victoria University HospitalCIBERCV.MalagaSpain Department of Haematology Hospital Clínico Universitario Virgen de la ArrixacaUniversity of MurciaMurciaSpain Department of Medical Affairs Bayer HispaniaBarcelonaSpain Department of Biochemistry and Molecular Biology-A University of MurciaMurciaSpain

Objectives To analyze the clinical profile,adequacy of treatment with rivaroxaban and outcomes in octogenarians with atrial fibrillation(AF),taking rivaroxaban in clinical *** Observational and non-interventional study that included AF adults recruited from 79 Spanish centers,anticoagulated with rivaroxaban ≥ 6 months before being *** were analyzed according to age(≥ 80 vs.nts,453(31.6%) were octogenarians at *** to younger patients,octogenarians had more comorbidities,higher CHA2DS2-VASc(4.5 ± 1.3 vs.3.0 ± 1.4;P nd HAS-BLED scores(2.0 ± 1.0 vs.1.4 ± 1.0;P n was adequately prescribed in 83.4% of patients,but more frequently in the younger population(71.1% vs.89.1%;P = 0.039).After a mean follow-up of 2.2 ± 0.6 years,annual rates of stroke + systemic embolism + transient ischemic attack,MACE,cardiovascular death and major bleeding were 1.03%,1.24%,1.03% and 1.75%,respectively,in octogenarian *** for progressive heart failure death and major bleeding,rates of outcomes in octogenarians were similar compared to younger *** octogenarians,the concomitant use of antiplatelet agents and non-severe dementia were independently associated with the development of ischemic stroke,whereas previous coronary revascularization and heart failure with MACE,and higher HAS-BLED score with major *** In clinical practice,around one third of patients taking rivaroxaban are *** patients have many comorbidities and a high thromboembolic *** that,rates of adverse events remain *** is adequately prescribed in the majority of octogenarians.

关键词： patients atrial bleeding

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Tailings Dam Mining, Theoretical Considerations, and Circular Economy: A Review

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Journal of Geoscience and Environment Protection 2024年第9期12卷 77-92页

作者： Eduardo da Rosa Aquino Vidal Félix navarro Torres Irvyn Laurence Paniz Instituto Tecnolgico Vale - Minerao Ouro Preto Brazil

Mining in tailings dams has emerged as a strategic alternative for mining companies for both economic and environmental reasons. Owing to technological limitations in recent decades, many of these dams have high metal contents, emphasizing the need to evaluate the quality of these residues, especially considering the technological advancements in current concentration plants. An economic viability analysis associated with reusing these materials is crucial. From an environmental point of view, improving mining techniques for dams by considering both safety and feasibility is an advantageous option in decommissioning processes and alignment in the circular economy. In this context, representing these tailings in terms of grade quality and granulometry, as well as the associated contaminants, is essential. Geostatistical estimation and simulation methods are valuable tools for modeling tailings bodies, but they require a reliable sampling campaign to ensure acceptably low errors. From an operational perspective, tailings recovery can be conducted via dry methods, such as mechanical excavation, or hydraulic methods, such as dredging or hydraulic blasting. Dredging is a commonly used method, and cutter suction dredgers, which require pumping to transport fragmented material, are the most commonly used tools. In this paper, some practical applications of geostatistical methods for resource quantification in tailings dams will be discussed. Additionally, the main mining methods for tailings recovery in dams will be presented. Emphasis will be given to the dredging method, along with the key analysis parameters for sizing dredgers, pumps, and pipelines.

关键词： Mining in Tailings Dams Geostatistical Methods Grade Quality Dredging

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Minimally Invasive Surgery for necrotizing Pancreatitis: A Case Report

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Surgical Science 2024年第9期15卷 514-521页

作者： néstor Veriel Méndez Huerta Luis Fernando Zorrilla núñez noelia Obregón Gaxiola César Jair Treviño Arizmendi Gerardo Iván Muñoz Morales Marco Alejandro Arizmendi Villarreal Pamela Denisse Valdez navarro Marco Antonio Hernández Guedea Gerardo Enrique Muñoz Maldonado Service of General Surgery Hospital Universitario Dr. Jos Eleuterio Gonzlez Universidad Autnoma de Nuevo Len Monterrey Mxico

Introduction: necrotizing pancreatitis management is complex and varies significantly among clinicians. Minimally invasive approaches like transgastric necrosectomy via laparoscopy are emerging as effective treatment options. This case report underscores the technique’s efficacy, clinical outcomes, and role in reducing complications. Clinical Observation: A 59-year-old male with a history of smoking and alcoholism presented with severe abdominal pain, nausea, and vomiting. Over the following weeks, he developed symptoms including asthenia, weight loss, and melena. Diagnostic workup revealed severe anemia and Balthazar E necrotizing pancreatitis, with significant intra-abdominal fluid collections and signs of infection. After initial conservative management, the patient underwent transgastric necrosectomy via laparoscopy due to deteriorating clinical status. The procedure involved removing necrotic tissue and performing a cystogastroanastomosis and jejunostomy. Postoperative care included fasting, parenteral nutrition, broad-spectrum antibiotics, and enzymatic replacement. The patient recovered well, with reduced necrotic tissue on follow-up imaging, and was discharged twelve days post-surgery [1]. Conclusion: Transgastric necrosectomy by laparoscopy is a valuable first-line surgical option for patients with symptomatic necrotizing pancreatitis, particularly in cases without prior interventions. This minimally invasive technique helps reduce major complications and mortality, offering a less invasive alternative to traditional open necrosectomy. The multidisciplinary approach and careful postoperative management were crucial to the patient’s favorable outcome. The case highlights the potential of transgastric necrosectomy as an effective treatment strategy in managing complex pancreatitis cases, including those with associated duodenal perforation [2].

关键词： necrotizing Transgastric Pancreatic necrosectomy Pancreatitis Case Report

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Omics-based biomarkers as useful tools in metabolic dysfunctionassociated steatotic liver disease clinical practice:How far are we?

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World Journal of Gastroenterology 2024年第14期30卷 1982-1989页

作者： Julieta Trinks María F Mascardi Adrián Gadano Sebastián Marciano Instituto de Medicina Traslacional e Ingeniería Biomédica-Consejo nacional de Investigaciones Científicas y Técnicas-Instituto Universitario del Hospital Italiano-Hospital Italiano de Buenos Aires Ciudad Autónoma de Buenos Aires C1199ACLArgentina Consejo nacional de Investigaciones Científicas y Técnicas Ciudad Autónoma de Buenos Aires C1425FQBArgentina Liver Unit Hospital Italiano de Buenos AiresCiudad Autónoma de Buenos Aires C1199DFArgentina Department of Research Hospital Italiano de Buenos AiresCiudad Autónoma de Buenos Aires C1199DFArgentina

Unmet needs exist in metabolic dysfunction-associated steatotic liver disease(MASLD)risk *** ability to identify patients with MASLD with advanced fibrosis and at higher risk for adverse outcomes is still *** novel biomarkers could represent a meaningful improvement to current risk *** this aim,omics technologies have revolutionized the process of MASLD biomarker discovery over the past *** the research in this field is thriving,much of the publication has been haphazard,often using single-omics data and specimen sets of convenience,with many identified candidate biomarkers but lacking clinical validation and *** we incorporate these biomarkers to direct patients’management,it should be considered that the roadmap for translating a newly discovered omics-based signature to an actual,analytically valid test useful in MASLD clinical practice is rigorous and,therefore,not easily *** article presents an overview of this area’s current state,the conceivable opportunities and challenges of omics-based laboratory diagnostics,and a roadmap for improving MASLD biomarker research.

关键词： Metabolic dysfunction-associated steatotic liver disease non-alcoholic steatohepatitis Biomarker Risk stratification Omics

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Unsupervised intrusion detection system for in-vehicle communication networks

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Journal of Safety Science and Resilience 2024年第2期5卷 119-129页

作者： Kabilan n Vinayakumar Ravi V Sowmya Center for Computational Engineering and networking(CEn) Amrita School of Artificial InteligenceAmrita Vishwa VidyapeethamCoimbatoreIndia Center for Artificial Intlligence Prince Mohammad Bin Fahd UniversityKhobarSaudi Arabia

In-vehicle communication has been optimized day to day to keep updated of the *** area network(CAn)is used as a standard communication method because of its efficient and reliable ***,CAn is prone to several network level attacks because of its lack in security *** methods have been introduced to incorporate this in *** proposed an unsupervised method of intrusion detection for in-vehicle communication networks by combining the optimal feature extracting ability of autoencoders and more precise clustering using fuzzy C-means(FCM).The proposed method is light weight and requires less computation *** performed an extensive experiment and achieved an accuracy of 75.51%with the ML35o in-vehicle intrusion *** experimental result,the proposed method also works better for other intrusion detection problems like wireless intrusion detection datasets such as WnS-DS with accuracy of 84.05%and network intrusion detection datasets such as KDDCup with accuracy 60.63%,UnSW_nB15 with accuracy 73.62%and Information Security Center of Excellence(Iscx)with accuracy 74.83%.Overall,the proposed method outperforms the existing methods and avoids labeled datasets when training an in-vehicle intrusion detection *** results of the experiment of our proposed method performed on various intru-sion detection datasets indicate that the proposed approach is generalized and robust in detecting intrusions and can be effectively deployed in real time to monitor CAn traffic in vehicles and proactively alert during attacks.

关键词： Controlarea network Intrusiondetection Unsupervised learning Autoencoders Fuzzy C-means

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Polyelectrolyte Complexes between Hyperbranched and Linear Polysaccharides: Fucoidan/Chitosan

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Chinese Journal of Polymer Science 2024年第4期42卷 468-479页

作者： Ekaterina R.Gasilova Daria n.Poshina Aleksandra O.Sitnikova natalia n.Saprykina Yury A.Skorik Institute of Macromolecular Compounds of the Russian Academy of Sciences Bolshoi VO 31St.Petersburg199004Russian Federation

Polyelectrolyte complexes(PECs)of hyperbranched(HB)and linear polysaccharides are promising as more effective encapsulation agents compared to PECs formed by linear *** investigated the PECs between the HB anionic polysaccharide fucoidan(FUC)and the cationic linear polysaccharide chitosan(CS).The FUC had a molecular weight(MW)of 30×*** PECs were prepared in three solvents(water,0.01 and 0.1 mol/L acetic acid)with CS of MW of 15,110 and 170 kDa,and deacetylation degrees(DDA)of 70%and 97%.The structures of the PECs and the initial FUC were investigated by multi-angle static and dynamic light *** the FUC contained 18 wt%of—OSO3 groups and 5 wt%of uronic acid units,it was a“strong-weak”copolyanion,so the HB macromolecules of the FUC formed nanogel particles in 0.1 mol/L AcOH and open branched structures in water,as confirmed by the Kratky *** mixing the solutions of original components,the PEC structures underwent an equilibration period,the duration of which increased with the MW of *** the charge stoichiometry was approached,the PECs shrank;the fractal dimension approached unity,indicating the side-by-side packing of adjacent FUC branches with the help of *** aggregation in the vicinity of the charge compensation was hardly observed,as it occurred in a very narrow *** PEC content at theζ-potential inversion depended on solvents’pH and the DDA of *** the extreme case of core-shell PECs in 0.1 mol/L AcOH,obtained by mixing FUC nanogels with the solutions of high MW CS of 97%DDA,the protruding tails of CS formed a positively charged shell in the whole range of FUC content(10 wt%nning electron microscopy and atomic force microscopy images of dried samples were discussed in relation to the light scattering results.

关键词： Polyelectrolyte complexes Chitosan Hyperbranched fucoidan Light scattering

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