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Food Science and Human Wellness 2023年第4期12卷 1265-1278页

作者： Wenqi Wang Yidi Qu Siyu Li jinyu chu Hongxin Yang Lirong Teng Di Wang School of Life Sciences Jilin UniversityChangchun 130012China

Curculigoside(CCG)is a phenolic glycoside compound extracted from the root of a natural plant called Curculigo orchioides *** this study,the neuroprotective effect of CCG through oxidative stress mediated mitochondrial dysfunction on L-glutamate(L-Glu)-damaged hippocampal neuron cell line(HT22)and APPswe/PSEN1dE9 transgenic(APP/PS1)mice were ***,CCG in L-Glu-damaged HT22 cells suppressed apoptosis,reduced the accumulation of reactive oxygen species,balanced the mitochondrial membrane potential and prevented the over-influx of *** APP/PS1 mice,4-week CCG administration significantly improved their memory and behavioral impairments,enhanced the function of cholinergic system,reduced the deposition of Aβand neurofibrillary fiber tangles caused by tau phosphorylation,and suppressed the development and progression of oxidative stress in brains of APP/PS1 *** on the screening of proteomic analysis on hippocampus,CCG were confirmed that it could regulate the expression levels of proteins related to mitochondrial dysfunction,mainly through activating on AMPK/Nrf2 signaling,in APP/PS1 mice and L-Glu-exposed HT22 *** has a prominent neuroprotective effect on regulate the AMPK/Nrf2-mediated mitochondrial dysfunction in cells APP/PS1 mice support CCG is a potentially potent drug for AD treatment and merits further investigation.

关键词： Alzheimer’s disease Curculigoside Apoptosis Oxidative stress Mitochondrial dysfunction AMPK/Nrf2 signaling

Research of the Purifying of Welding Fume on the Spot with Corona Plasma

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Journal of Environmental Science and Engineering 2010年第1期4卷 61-64页

作者： Yansheng Du chunduWu jinyu chu School of the Environment Jiangsu Universigy Zhenjiang 212013 China

The welding fume has significant effects on the weld workers＇ health. In order to overwhelm the shortcomings of the control measures of the welding fume, the research of the purifying of welding fume on the spot was carried out. The purifying device was designed. The relationship between the corona discharge voltage and the purifying efficiency was investigated through experiments with different needle electrode numbers, different ring electrode numbers and different needle-plate distances. The results show that 5-needle double-ring electrode has the best efficiency; the purifying efficiency is increase with the lessening of the needle-plate distance and the increase of the discharge voltage. Using 5-needle double-ring electrode, the purifying efficiency reaches its maximum value 97.9% while the needle-plate distance is 6 cm, the discharge voltage is -35 kV. The purifying device has an excellent purifying effect on the welding fume.

关键词： Corona plasma welding fume purifying on the spot.

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自由基降解甲基橙溶液试验

江苏大学学报（自然科学版） 2010年第4期31卷 469-472页

作者：储金宇樊迪江苏大学环境学院江苏镇江212013

针对含有偶氮类难降解有机物的染料废水具有色度大,生物可降解性低,难于处理等特点,模拟了有典型偶氮结构的甲基橙染料废水,对强电离放电产生的自由基溶液降解甲基橙进行了研究,讨论了pH值、甲基橙溶液初始质量浓度、自由基溶液质量浓... 详细信息

针对含有偶氮类难降解有机物的染料废水具有色度大,生物可降解性低,难于处理等特点,模拟了有典型偶氮结构的甲基橙染料废水,对强电离放电产生的自由基溶液降解甲基橙进行了研究,讨论了pH值、甲基橙溶液初始质量浓度、自由基溶液质量浓度、温度以及反应时间等因素对甲基橙溶液降解性能的影响.结果表明,酸性条件有利于甲基橙溶液的降解,pH=1.5时,自由基氧化降解200 mg/L的甲基橙溶液3 min后,其COD的去除率和脱色率最大值分别达到86.87%和88.53%.对比甲基橙溶液处理前后紫外可见光谱图的变化,发现经自由基降解后,偶氮键及苯环都受到破坏,大部分甲基橙分子已经氧化分解.

关键词：甲基橙自由基强电离放电偶氮染料染料废水

Ni-MCM-41的水热合成与稳定性(英文)

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硅酸盐学报 2008年第9期36卷 1256-1261页

作者：赵谦储金宇姜廷顺殷恒波江苏大学化学化工学院环境学院江苏镇江212013

以硅酸钠(Na2SiO3·9H2O)、氯化镍(NiCl2·6H2O)等无机盐为原料,通过水热法合成含有不同镍含量的介孔分子筛(nickel-containing meso-porousmolecular sieve,Ni-MCM–41)。采用X射线粉末衍射、等离子发射光谱、程序升温还原,透射电子显... 详细信息

以硅酸钠(Na2SiO3·9H2O)、氯化镍(NiCl2·6H2O)等无机盐为原料,通过水热法合成含有不同镍含量的介孔分子筛(nickel-containing meso-porousmolecular sieve,Ni-MCM–41)。采用X射线粉末衍射、等离子发射光谱、程序升温还原,透射电子显微镜和N2吸附–脱附等技术对焙烧后的样品的物化性能进行表征,同时对所合成Ni-MCM–41的水热稳定性进行研究。结果表明:在水热条件下成功合成出4种不同镍含量的Ni-MCM–41,其比表面积在495.9～888.2 m2/g之间,平均孔径在2.43～2.92 nm之间。随着介孔分子筛中金属镍含量的增加,Ni-MCM–41的比表面积、孔体积变小和介孔有序性变差。原料摩尔比n(SiO2):n(NiO)=1:0.05时,合成的Ni-MCM–41的介孔有序性最好。所合成的含Ni-MCM–41经750℃焙烧3h后仍然具有介孔结构;另一方面,经100℃水热处理5d后的样品也具有介孔结构,但介孔有序性差。

关键词：含镍介孔分子筛稳定性合成表征介孔有序性

Study on Dry Type Calcium-sprayed Desulphurization by Plasma

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Study on Dry Type Calcium-sprayed Desulphurization by Plasma

Hydrochloric acid‐mediated synthesis of ZnFe_(2)O_(4) small particle decorated one‐dimensional Perylene Diimide S‐scheme heterojunction with excellent photocatalytic ability

亚太绿色氧化还原技术国际研讨会

作者： Wu chundu Yi Chengwu* Ou Hongxiang chu jinyu Yan Jun Jiangsu University Environmental College Zhenjiang China 212013

The lime-hydrate(Ca(OH)2)desulfurizer is treated by plasma with strong ionization discharge of dielectric barrier, study of De-SO2 from simulative flue gas has been performed in this paper, and desulf

关键词： plasma strong ionization discharge Ca(OH)2 SO2 desulfurization

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Chinese Journal of Catalysis 2022年第4期43卷 1111-1122页

作者： Yangrui Xu Xiaodie Zhu Huan Yan Panpan Wang Minshan Song Changchang Ma Ziran Chen jinyu chu Xinlin Liu Ziyang Lu Institute of Environmental Health and Ecological Security School of the Environment and Safety EngineeringJiangsu UniversityZhenjiang 212013JiangsuChina School of Science Jiangsu University of Science and TechnologyZhenjiang 212003JiangsuChina Department of Chemistry Dongguk UniversitySeoul 04620South Korea School of Energy and Power Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina Department of Mechanical&Materials Engineering Portland State UniversityPortlandORUSA Department of Chemistry University of TennesseeTennesseeKnoxville 37996USA Department of Architecture and Environment Engineering Sichuan Vocational and Technical CollegeSuining 629000SichuanChina Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment Suzhou University of Science and TechnologySuzhou 215009JiangsuChina

The recyclable and stable ZnFe_(2)O_(4) small particle decorated one‐dimensional perylene diimide(PDI)S‐scheme heterojunction(1D PDI/ZnFe_(2)O_(4))is prepared by the hydrochloric acid‐mediated(HCl‐mediated)strategy,interestingly,the morphology of the 1D PDI/ZnFe_(2)O_(4) can also be effectively regulated by HCl‐mediated process,the existence of HCl can regulate PDI into a uniform rod structure,while the co‐existence of HCl and PDI can limit ZnFe_(2)O_(4) to become the uniform small *** importantly,based on the 1D rod structure of PDI and the small size effect of ZnFe_(2)O_(4),carriers can migrate to the surface more easily,which can improve the photocatalytic ***,due to the appropriate energy level structure,the S‐scheme heterojunction structure is formed between PDI and ZnFe_(2)O_(4),which eliminates meaningless photo‐generated charge carriers through recombination and introduces strong redox to further enhance the photodegradation effect,thereby,1D PDI/ZnFe_(2)O_(4) exhibits excellent photocatalytic ability,under the visible light irradiation,the degradation rate of tetracycline(TC)with 1D PDI/ZnFe_(2)O_(4)(66.67%)is 9.18 times that with PDI(7.26%)and 9.73 times that with ZnFe_(2)O_(4)(6.85%).This work proposes new ideas for the assembly of magnetic organic‐inorganic S‐scheme heterojunction photocatalysts.

关键词： Hydrochloric acid‐mediated strategy Morphology regulation Perylene diimide/ZnFe_(2)O_(4) S‐scheme heterojunction Photocatalytic ability

单细胞转录组鉴定阿尔茨海默病外周血生物标志物GZMK~+CD8~+T细胞

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四川大学学报（医学版） 2023年第5期54卷 863-873页

作者：段婷婷初金语胡斐斐武汉科技大学医学院脑科学先进技术研究院武汉430081 武汉科技大学附属亚洲心脏病医院武汉430022

目的基于单细胞RNA测序(single cell RNA sequencing,scRNA-seq)挖掘阿尔茨海默病(Alzheimer's disease,AD)外周血免疫特征作为生物标志物,系统性探索AD外周血免疫细胞亚型丰度、基因表达特征和细胞通讯异常。方法从GEO数据库中下载AD... 详细信息

目的基于单细胞RNA测序(single cell RNA sequencing,scRNA-seq)挖掘阿尔茨海默病(Alzheimer's disease,AD)外周血免疫特征作为生物标志物,系统性探索AD外周血免疫细胞亚型丰度、基因表达特征和细胞通讯异常。方法从GEO数据库中下载AD外周血免疫细胞scRNA-seq数据集GSE168522,于RAD-Blood网页服务器(http://***/RAD-Blood/)中分析AD患者血液细胞组成成分变化,利用CellChat分析AD患者血液中异常的细胞间通讯作用。结果AD患者和健康人血液中有两种CD8^(+)T细胞,其中一类高表达颗粒酶K(granzyme K,GZMK)[伪发现率(false discovery rate,FDR)<0.05],另一类高表达GZMA、GZMB和GZMH(FDR<0.05)。GZMK^(+)CD8^(+)T细胞在AD患者血液中含量升高32.9%(P=5.15E-21),与其他细胞类型的交互作用增加,并可能通过主要组织相容性复合体Ⅰ类(major histocompatibility complex classⅠ,MHC-Ⅰ)信号转导异常与AD关联,红细胞为GZMK^(+)CD8^(+)T细胞MHC-Ⅰ信号通路异常提供了主要配体,即人类白细胞抗原(human leukocyte antigen,HLA)Ⅰ类分子(HLA-A、HLA-B、HLA-C和HLA-E)。血液RESISTIN信号通路仅富集于AD患者血液中,其可能是AD血液特异性信号通路。结论外周血GZMK^(+)CD8^(+)T细胞含量升高、GZMK^(+)CD8^(+)T细胞与红细胞的交互作用增加、RESISTIN通路增强是潜在的AD标志物。

关键词：阿尔茨海默病单细胞RNA测序血液生物标志物 CD8^(+)T细胞

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基于等离子体的干法脱硫试验研究

高电压技术 2006年第10期32卷 69-71页

作者：陈志刚严军储金宇依成武江苏大学生物与环境工程学院镇江212013

为解决干法脱硫存在的烟气停留时间长,脱硫效率低等问题,采用等离子体技术与传统干式喷钙脱硫技术相结合,研究了脉冲放电脱硫的运行参数对脱硫效果的影响,脉冲放电脱硫反应器采用线筒式电极结构,试验烟气流量为100m3/h。试验结果表明,... 详细信息

为解决干法脱硫存在的烟气停留时间长,脱硫效率低等问题,采用等离子体技术与传统干式喷钙脱硫技术相结合,研究了脉冲放电脱硫的运行参数对脱硫效果的影响,脉冲放电脱硫反应器采用线筒式电极结构,试验烟气流量为100m3/h。试验结果表明,工作电压为22kV,Ca/S=1.5,运行温度θ=25°C,烟气停留时间t=2.8s,φ(SO2)=1.800×10-3,烟气水分的体积分数φ(H2O)=2.1%时,脱硫率可达80.2%。

关键词：等离子体荷电脱硫运行参数电晕放电

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臭氧氧化处理长江低含油量压载水试验

江苏大学学报（自然科学版） 2010年第2期31卷 221-224页

作者：储金宇蔡笑笑樊迪管荷兰江苏大学环境学院江苏镇江212013

为控制含油压载水对长江生态环境的污染,对臭氧氧化方法深度处理含油压载水的技术原理进行分析,并就臭氧质量浓度、水体温度、氧化时间等因素对处理效果的影响进行试验研究.试验结果表明,臭氧质量浓度达到8.28 mg/L,在较短的接触时间(8 ... 详细信息

为控制含油压载水对长江生态环境的污染,对臭氧氧化方法深度处理含油压载水的技术原理进行分析,并就臭氧质量浓度、水体温度、氧化时间等因素对处理效果的影响进行试验研究.试验结果表明,臭氧质量浓度达到8.28 mg/L,在较短的接触时间(8 min)内,臭氧对不同油品的质量浓度在20mg/L左右的压载水中油去除率可达90%以上.在臭氧氧化过程中,温度对石油类的去除影响并不明显,但pH值对去除率影响显著,并且随着反应过程的深入,原水pH值及COD都有所下降.

关键词：压载水臭氧氧化除油去除率含油废水

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脉冲放电等离子体再生吸附AO7饱和活性碳

高电压技术 2015年第1期41卷 251-256页

作者：储金宇刘永杰王慧娟依成武江苏大学环境与安全工程学院镇江212013

为了说明脉冲放电等离子体对吸附有机物饱和活性炭的再生作用,以酸性橙II(AO7)为目标物,建立了吸附AO7饱和活性炭的气液混合的脉冲放电等离子体再生体系,考察了该再生体系中的关键因素,包括水溶液电导率、载气流速、活性炭量及再生时间... 详细信息

为了说明脉冲放电等离子体对吸附有机物饱和活性炭的再生作用,以酸性橙II(AO7)为目标物,建立了吸附AO7饱和活性炭的气液混合的脉冲放电等离子体再生体系,考察了该再生体系中的关键因素,包括水溶液电导率、载气流速、活性炭量及再生时间对活性炭再生效果的影响规律。研究结果表明:一定的放电操作参数下,在实验所考察的参数变化范围内,增加水溶液电导率,减少活性炭投加量,活性炭的再生效率随之提高;较高的水溶液电导率(1 000μS/cm)和较低的活性炭添加量(1 g)有利于活性炭再生;适宜的载气流速(2 L/min)和放电作用时间(60 min)下的活性炭再生效率较高;相应操作条件下的活性炭在20.4 kV脉冲峰值电压和50 Hz脉冲频率的等离子体作用体系中的再生效率可达71.6%。

关键词：脉冲放电等离子体气-液混合活性炭酸性橙Ⅱ 再生效果