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任务转换影响词对记忆:提取练习的补偿作用

心理科学 2024年第2期47卷 308-315页

作者：肖晶晶张俐娟陈登水罗爽张锦坤福建师范大学心理学院福州350100

移动智能终端的应用提高了个体学习过程中的任务转换频率,重复练习可缓解判断类任务转换对速度和准确性的损害,但其对记忆任务的影响尚未明确。研究采用2(练习方式:重学,提取练习)×2(任务转换:是,否)×2(测试时间:初始,延迟)混合设计,... 详细信息

移动智能终端的应用提高了个体学习过程中的任务转换频率,重复练习可缓解判断类任务转换对速度和准确性的损害,但其对记忆任务的影响尚未明确。研究采用2(练习方式:重学,提取练习)×2(任务转换:是,否)×2(测试时间:初始,延迟)混合设计,考察不同练习方式的记忆类任务转换是否存在类似促进效应。结果发现,不同练习方式下任务转换均损害记忆准确性;初始和延迟测试(48h)中提取练习的记忆准确性均高于重学。研究表明,任务转换对记忆的损害源于任务集切换,但提取在记忆建构和搜索上的优势加强了记忆痕迹,对任务转换中的重复任务具有补偿作用。

关键词：任务转换成本提取练习记忆

提取练习效应中的编码与提取:对立还是融合?

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心理研究 2024年第4期17卷 308-314页

作者：廖陈陈张锦坤福建师范大学心理学院福州350108

在等同时间内对信息进行提取比重复阅读产生更持久的记忆保持,即提取练习效应(retrieval practice effect,RPE)。精细提取假说认为RPE是由于提取过程中精加工导致的语义激活增强了记忆保持;情景背景假说认为对事件背景进行的重构和更新... 详细信息

在等同时间内对信息进行提取比重复阅读产生更持久的记忆保持,即提取练习效应(retrieval practice effect,RPE)。精细提取假说认为RPE是由于提取过程中精加工导致的语义激活增强了记忆保持;情景背景假说认为对事件背景进行的重构和更新促进了记忆保持。论文梳理和比较了两个理论的行为和神经机制证据,分析了二者在提取线索和提取激活脑区上的差异,指出编码与提取在RPE中并非完全对立而是相互融合。未来研究可进一步验证情景背景假说,结合认知神经科学检验提取过程中背景回忆和语义精加工的交互作用,并拓展神经机制研究中使用的学习材料和记录方法。

关键词：提取练习效应精细提取假说情景背景假说神经机制

Multiphase Interfacial Regulation Based on Hierarchical Porous Molybdenum Selenide to Build Anticorrosive and Multiband Tailorable Absorbers

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Nano-Micro Letters 2024年第1期16卷 85-105页

作者： Tianbao Zhao Zirui Jia jinkun Liu Yan zhang Guanglei Wu Pengfei Yin College of Science Sichuan Agricultural UniversityYa’an 625014People’s Republic of China Institute of Materials for Energy and Environment State Key Laboratory of Bio‑Fibers and Eco‑TextilesCollege of Materials Science and EngineeringQingdao UniversityQingdao 266071People’s Republic of China College of Chemistry and Chemical Engineering Qingdao UniversityQingdao 266071People’s Republic of China

Electromagnetic wave(EMW)absorbing materials have an irreplaceable position in the field of military stealth as well as in the field of electromagnetic pollution *** in order to cope with the complex electromagnetic environment,the design of multifunctional and multiband high efficiency EMW absorbers remains a tremendous *** this work,we designed a three-dimensional porous structure via the salt melt synthesis strategy to optimize the impedance matching of the ***,through interfacial engineering,a molybdenum carbide transition layer was introduced between the molybdenum selenide nanoparticles and the three-dimensional porous carbon matrix to improve the absorption behavior of the *** analysis indicates that the number and components of the heterogeneous interfaces have a significant impact on the EMW absorption performance of the absorber due to mechanisms such as interfacial polarization and conduction loss introduced by interfacial ***,the prepared MoSe_(2)/MoC/PNC composites showed excellent EMW absorption performance in C,X,and Ku bands,especially exhibiting a reflection loss of−59.09 dB and an effective absorption bandwidth of 6.96 GHz at 1.9 *** coordination between structure and components endows the absorber with strong absorption,broad bandwidth,thin thickness,and multi-frequency absorption ***,it can effectively reinforce the marine anticorrosion property of the epoxy resin coating on Q235 steel *** study contributes to a deeper understanding of the relationship between interfacial engineering and the performance of EMW absorbers,and provides a reference for the design of multifunctional,multiband EMW absorption materials.

关键词： Interfacial engineering Anticorrosion Multiband Electromagnetic wave absorber

Elucidating Structures of Complex Organic Compounds Using a Machine Learning Model Based on the 13C NMR Chemical Shifts

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Precision Chemistry 2023年第1期1卷 57-68页

作者： Anan Wu Qing Ye Xiaowei Zhuang Qiwen Chen jinkun zhang Jianming Wu Xin Xu Department of Chemistry College of Chemistry and Chemical EngineeringFujian Provincial Key Laboratory of Theoretical and Computational ChemistryXiamen UniversityXiamen 361005China Collaborative Innovation Center of Chemistry for Energy Materials Shanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsMOE Key Laboratory of Computational Physical SciencesDepartment of ChemistryFudan UniversityShanghai 200438China Hefei National Laboratory Hefei 230088China

We present a protocol that combines the support vector machine(SVM)model with accurate 13C chemical shift calculations at the xOPBE/6-311+G(2d,p)level of theory,denoted as SVM-M(i.e.,SVM for magnetic property).We show here that this SVM-M protocol is a versatile tool for identifying the structural and stereochemical assignment of complex organic compounds with high *** particular significance is that,by utilizing the dual role of the decision values in SVM,the present SVM-M protocol provides an accurate yet efficient solution to simultaneously handle the classification issue(i.e.,“is a given structure correct or incorrect?”)and the comparison-based problem(i.e.,“which structure is more likely to be correct or wrong among several candidate structures?”).A significantly high success rate has been reached(i.e.,∼100%on a set of 760 sample molecules with 1592813C chemical shifts),which makes the SVMM protocol a powerful tool for routine applications in structural and stereochemical assignments,as well as in detecting misassignments,for complex organic compounds,including natural products.

关键词： NMR Machine learning Structure elucidation Support vector machine DFT

Polyketides with potential bioactivities from the mangrove‑derived fungus Talaromyces ***0362

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Marine Life Science & Technology 2023年第2期5卷 232-241页

作者： Huawei Lv Haibo Su Yaxin Xue Jia Jia Hongkai Bi Shoubao Wang jinkun zhang Mengdi Zhu Mahmoud Emam Hong Wang Kui Hong Xing-Nuo Li College of Pharmaceutical Science&Key Laboratory of Marine Fishery Resources Exploitment&Utilization of Zhejiang Province Zhejiang University of TechnologyHangzhou 310014China School of Pharmaceutical Sciences Wuhan UniversityWuhan 430072China Department of Pathogen Biology&Jiangsu Key Laboratory of Pathogen Biology Nanjing Medical UniversityNanjing 211166China Beijing Key Laboratory of Drug Target Research and New Drug Screening Institute of Materia MedicaChinese Academy of Medical SciencesBeijing 100700China Research Center of Analysis and Measurement Zhejiang University of TechnologyHangzhou 310014China Department of Phytochemistry and Plant Systematics National Research CentreGizaEgypt

Metabolites of microorganisms have long been considered as potential sources for drug *** this study,fve new depsidone derivatives,talaronins A-E(1-5)and three new xanthone derivatives,talaronins F-H(6-8),together with 16 known compounds(9-24),were isolated from the ethyl acetate extract of the mangrove-derived fungus Talaromyces species *** structures were elucidated by analysis of spectroscopic data and chemical methods including alkaline hydrolysis and Mosher’s *** 1 and 2 each attached a dimethyl acetal group at the aromatic ring.A putative biogenetic relationship of the isolated metabolites was presented and suggested that the depsidones and the xanthones probably had the same biosynthetic precursors such as chrysophanol or *** antimicrobial activity assay indicated that compounds 5,9,10,and 14 showed potent activity against Helicobacter pylori with minimum inhibitory concentration(MIC)values in the range of 2.42-36.04μmol/*** secalonic acid D(19)demonstrated signifcant antimicrobial activity against four strains of *** with MIC values in the range of 0.20 to 1.57μmol/***,secalonic acid D(19)exhibited cytotoxicity against cancer cell lines Bel-7402 and HCT-116 with IC_(50) values of 0.15 and 0.19μmol/L,*** structure–activity relationship of depsidone derivatives revealed that the presence of the lactone ring and the hydroxyl at C-10 was crucial to the antimicrobial activity against *** depsidone derivatives are promising leads to inhibit *** and provide an avenue for further development of novel antibiotics.

关键词： Mangrove-derived fungus Talaromyces sp. Depsidone Xanthone Antimicrobial

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用于水面环境的激光惯导融合里程计算法

桂林航天工业学院学报 2024年第3期29卷 425-432页

作者：王池华陈倩胡大开何树光刘峻瑜林家颖廖彬涵张锦昆广西综合交通大数据研究院广西南宁530001 桂林电子科技大学建筑与交通工程学院广西桂林541004 广西北港大数据科技有限公司广西南宁530001 广西北部湾国际港务集团有限公司广西南宁530001 南宁桂电电子科技研究院有限公司广西南宁530001 桂林电子科技大学信息与通信学院广西桂林541001

针对现有激光里程计算法在水面环境上难以提取特征点,在位姿匹配时容易发生漂移导致精度低的问题,文章提出一种基于误差状态卡尔曼滤波(Error State Kalman Filter, ESKF)的激光雷达和惯性测量单元(IMU)融合的里程计算法。首先,对输入... 详细信息

针对现有激光里程计算法在水面环境上难以提取特征点,在位姿匹配时容易发生漂移导致精度低的问题,文章提出一种基于误差状态卡尔曼滤波(Error State Kalman Filter, ESKF)的激光雷达和惯性测量单元(IMU)融合的里程计算法。首先,对输入的点云进行预处理和运动畸变补偿,接着使用一种改进的特征提取方式筛选出平面特征和边缘特征,依据这两类特征构建改进的位姿残差优化方程,求解出相邻激光帧的位姿;其次,在IMU所在的线程中,根据加速度计和角速度计的输出值预测位姿,然后结合点云匹配给出的位姿构建ESKF,最后,使用更新后的误差状态量补偿系统的运动状态。实验对比结果表明,此算法相比现有的方法有效降低了相对位姿误差和累积误差,提高了激光里程计位姿匹配时的精度和建图的效果。

关键词：激光里程计误差状态卡尔曼滤波特征点匹配回环检测激光SLAM

A k-mer-based pangenome approach for cataloging seed-storage-protein genes in wheat to facilitate genotype-to-phenotype prediction and improvement of end-use quality

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Molecular Plant 2024年第7期17卷 1038-1053页

作者： Zhaoheng zhang Dan Liu Binyong Li Wenxi Wang Jize zhang Mingming Xin Zhaorong Hu Jie Liu jinkun Du Huiru Peng Chenyang Hao Xueyong zhang Zhongfu Ni Qixin Sun Weilong Guo Yingyin Yao Frontiers Science Center for Molecular Design Breeding Key Laboratory of Crop Heterosis and Utilization(MOE)and Bejing Key Laboratory of Crop Genetic ImprovementChina Agricultural UniversityBeijing100193China Key Laboratory of Crop Gene Resources and Breeding Institute of Crop ScienceChinese Academy of Agricultural SciencesBejingChina

Wheat is a staple foodfor more than 35%of the world's population,with wheatflourused to make hundreds of baked *** end-use quality is a major breeding target;however,improving it is especially time-consuming and ***,genes encoding seed-storage proteins(ssPs)form multigene families and are repetitive,with gaps commonplace in several genome *** overcome these barriers and efficiently identify superior wheat SSP alleles,we developed"PanSK"(Pan-SSP k-mer)for genotype-to-phenotype prediction based on an SsP-based pangenome *** uses 29-mer sequences that represent each ssP gene at the pangenomic level to reveal untapped diversity across landraces and modern ***-wide association studies with k-mers identified 23 Ssp genes associated with end-use quality that represent novel targets for *** evaluated the effect of rye secalin genes on end-use quality and found that removal of w-secalins from 1BL/1RS wheat translocation lines is associated with enhanced end-use ***,using machine-learning-based prediction inspired by PanSK,we predicted the quality phenotypes with high accuracy from genotypes *** study provides an effective approach for genome design based on ssP genes,enabling the breeding of wheat varieties with superior processing capabilities and improved end-use quality.

关键词： wheat seed-storage protein end-use quality k-mer pangenome genomic prediction

塔式太阳能辅助超超临界燃煤电站耦合方案研究

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锅炉技术 2023年第4期54卷 18-23页

作者：张锦坤王渡黄嘉上海电力大学能源与机械工程学院上海200090

为了充分的利用塔式太阳能集热场的能量,提出将塔式太阳能集热场与超超临界燃煤机组耦合的新型发电系统。太阳能可取代的锅炉受热面为省煤器段、低温过热段、一次再热器蒸汽低温段,结合能量梯级利用原理,提出4种耦合方案,通过Ebsilon热... 详细信息

为了充分的利用塔式太阳能集热场的能量,提出将塔式太阳能集热场与超超临界燃煤机组耦合的新型发电系统。太阳能可取代的锅炉受热面为省煤器段、低温过热段、一次再热器蒸汽低温段,结合能量梯级利用原理,提出4种耦合方案,通过Ebsilon热力系统仿真软件进行建模和分析。对于使用二代熔融盐的塔式太阳能热电站与超超临界参数燃煤机组的耦合方案进行研究比较,结果表明:使用太阳能的热量加热锅炉尾部烟道受热面内流经的工质最适宜。同时,集热场中的熔融盐给水换热器与省煤器并联、熔融盐蒸汽换热器与一次低温再热器并联的效果最好。相较于原机组,可提高1.98%的机组热效率和1.7%的机组效率,并降低9.41g/(kW·h)的机组供电标准煤耗率。

关键词：二代熔融盐超超临界参数太阳能辅助燃煤发电系统耦合方案

Protective effects of Buyinqianzheng Formula on mitochondrial morphology by PINK1/Parkin pathway in SH-SY5Y cells induced by MPP^(+)

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Journal of Traditional Chinese Medical Sciences 2020年第3期7卷 274-282页

作者： Haojie Ma Zhenyu Guo Cong Gai Cuicui Cheng jinkun zhang Yuxin zhang Luping Yang Wandi Feng Yushan Gao Hongmei Sun School of Chinese Medicine Beijing University of Chinese MedicineBeijing102488China

Objective:Buyinqianzheng Formula(BYQZF)is clinically employed in traditional Chinese medicine to treat Parkinson's disease(PD)by improving mitochondrial ***,the underlying mechanisms by which BYQZF affects mitochondrial morphology remain ***,we observed the effects of BYQZF on mitochondria from the perspective of the PINK1/Parkin ***:Cell survival rates were assessed by Cell Counting Kit-8 *** levels of PINK1 and Parkin mRNA were examined by *** expression levels of PINK1,PINK1-Ser228,Parkin,Parkin-Ser65,Drp1,and Drp1-Ser637 were examined by western ***1,Parkin,and MitoTracker?Red CMXRos(MTR)were stained by triple-labeled immunofluorescence,and observed under laser confocal ***:Cell survival rate,mitochondrial form factor,mean length and number of mitochondrial network branches,mitochondrial activity,m RNA expression levels of PINK1 and Parkin,and protein expression levels of PINK1,Parkin,and Drp1-Ser637 were reduced after 1-methyl-4-phenylpyridinium(MPP^(+))*** contrast,Pearson's correlation coefficients between PINK1 and Parkin,and between Parkin and MTR,as well as protein expression levels of PINK1-Ser228,Parkin-Ser65,and Drp1 increased significantly after MPP^(+) *** with BYQZF increased cell survival rate,mitochondrial form factor,mean length and number of mitochondrial network branches,mitochondrial activity,m RNA expression levels of PINK1 and Parkin,and expression of PINK1,Parkin,and Drp1-Ser637 ***'s correlation coefficients between PINK1 and Parkin,and between Parkin and MTR,as well as protein expression levels of PINK1-Ser228,Parkin-Ser65,and Drp1 decreased after BYQZF ***:These results demonstrate that BYQZF has a protective effect on mitochondrial molecular mechanisms in the PD cell model,and the mechanism is related to the PINK1/Parkin pathway.

关键词： BYQZF Parkinson's disease MPP^(+) Mitochondria PINK1/Parkin pathway