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Chinese Journal of Chemical Engineering 2024年第6期70卷 269-279页

作者： Shuyi Shen Song Guo Sining Chen jinhua zhao Nanjing University of Science&Technology Nanjing 210094China China Academy of Safety Science and Technology Beijing 100012China

Recently,azobenzene-4,4'-dicarboxylic acid(ADCA)has been produced gradually for use as an organic synthesis or pharmaceutical intermediate due to its eminent *** large quantities put into application in the future,the thermal stability of this substance during storage,transportation,and use will become quite ***,in this work,the thermal decomposition behavior,thermal decomposition kinetics,and thermal hazard of ADCA were *** were conducted by using a SENSYS evo DSC device.A combination of differential iso-conversion method,compensation parameter method,and nonlinear fitting evaluation were also used to analyze thermal kinetics and mechanism of ADCA *** results show that when conversion rate α increases,the activation energies of ADCA's first and main decomposition peaks *** amount of heat released during decomposition varies between 182.46 and 231.16 J·g^(-1).The proposed kinetic equation is based on the Avrami-Erofeev model,which is consistent with the decomposition *** the Frank-Kamenetskii model,a calculated self-accelerating decomposition temperature of 287.0℃is obtained.

关键词： Azobenzene-4,4′-dicarboxylic acid Thermal decomposition behavior Kinetic mechanism Thermal hazard evaluation Compensation parameter effect

Dopamine Inhibits the Expression of Hepatitis B Virus Surface and e Antigens by Activating the JAK/STAT Pathway and Upregulating Interferon-stimulated Gene 15 Expression

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Journal of Clinical and Translational Hepatology 2024年第5期12卷 443-456页

作者： Xiaoquan Liu Xiuqing Pang Zhiping Wan jinhua zhao Zhiliang Gao Hong Deng Department of Infectious Diseases Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongChina Guangdong Key Laboratory of Liver Disease Research Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou GuangdongChina Key Laboratory of Tropical Disease Control(Sun Yat-sen University) Ministry of EducationGuangzhouGuangdongChina

Background and Aims:Hepatitis B virus(HBV)infection is a major risk factor for cirrhosis and liver cancer,and its treatment continues to be *** previously demonstrated that a dopamine analog inhibited the packaging of pregenomic RNA into *** present study aimed to determine the effect of dopamine on the expressions of hepatitis B virus surface and e antigens(HBsAg and HBeAg,respectively)and to elucidate the underlying ***:We used dopamine-treated HBVinfected HepG2.2.15 and NTCP-G2 cells to monitor HBsAg and HBeAg expression *** analyzed interferon-stimulated gene 15(ISG15)expression in dopamine-treated *** knocked down ISG15 and then monitored HBsAg and HBeAg expression *** analyzed the expression of Janus kinase(JAK)/signal transducer and activator of transcription(STAT)pathway factors in dopamine-treated *** used dopamine hydrochloride-treated adeno-associated virus/HBV-infected mouse model to evaluate HBV DNA,HBsAg,and HBeAg *** virus was collected from HepAD38.7 cell culture ***:Dopamine inhibited HBsAg and HBeAg expression and upregulated ISG15 expression in HepG2.2.15 and HepG2-NTCP cell ***15 knockdown increased HBsAg and HBeAg expression in HepG2.2.15 ***-treated cells activated the JAK/STAT pathway,which upregulated ISG15 *** the adeno-associated virus-HBV murine infection model,dopamine downregulated HBsAg and HBeAg expression and activated the JAK-STAT/ISG15 ***:Dopamine inhibits the expression of HBsAg and HBeAg by activating the JAK/STAT pathway and upregulating ISG15 expression.

关键词： Hepatitis B virus Dopamine JAK-STAT/ISG15 axis HBV surface antigen HBV e antigen HepG2.2.15 cell line Human NTCP-expressing HepG2 cell line HepAD38 cell line

Organic-inorganic fertilization promotes paddy soil macroaggregate organic carbon accumulation associated with key bacterial populations in subtropical China

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Pedosphere 2024年第5期34卷 941-950页

作者： jinhua zhao Lin CHEN Guixiang ZHOU Fang LI Jiabao ZHANG Congzhi ZHANG Donghao MA Biao FENG Fengqiu Experimental Station of National Ecosystem Research Network of China State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences University of Chinese Academy of Sciences College of Resources and Environment Henan Agricultural University

Macroaggregate organic carbon (Macro-OC) accumulation in paddy soils is of great significance in promoting multiple agroecosystem services. However,the effects of different fertilization practices on Macro-OC accumulation in paddy soils at the regional scale have not been comprehensively ***, we conducted long-term fertilization field experiments at four sites, Taoyuan, Wangcheng, Jinxian, and Suzhou, in the subtropical area of China to reveal the effects of inorganic and organic-inorganic (OIF) fertilization on Macro-OC accumulation and its relationships with important microbial traits (the abundance ratio of GH48:cbhI genes and the richness of keystone bacterial taxa) in paddy soils. The results showed that long-term fertilization (particularly OIF) significantly increased the content of Macro-OC, which mainly consisted of particulate organic carbon (C). Organic-inorganic fertilization decreased the percentage of O-alkyl C but increased the percentages of alkyl, aromatic, and phenolic C. Organic-inorganic fertilization promoted the abundance of the bacterial cellulose-degrading gene GH48 retrieved from macroaggregates. The orders Anaerolineales, Bacillales, and Clostridiales were identified as keystone bacterial taxa in macroaggregates and were significantly correlated with the physical fraction and chemical structure of Macro-OC. Structural equation modeling revealed that fertilization-induced changes in soil pH and C:N ratio affected the richness of Anaerolineales, Bacillales, and Clostridiales, which was strongly associated with the increase of percentages of aromatic and phenolic C and further facilitated Macro-OC accumulation. Together, these results suggested that OIF promoted Macro-OC accumulation associated with key bacterial populations in paddy soils. The results provide an important basis for boosting soil C accrual in the subtropical rice-growing areas.

关键词： bacterial community keystone bacterial taxa mean weight diameter mineral-associated organic carbon particulate organic carbon structural equation modeling

高中压转子用30Cr1MoV钢动态再结晶行为及晶粒尺寸预测

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锻压技术 2024年第8期49卷 239-248页

作者：庞锦何文武赵金华杨斌太原科技大学材料科学与工程学院山西太原030024

为了研究高中压转子用30Cr1MoV钢在热变形过程中的动态再结晶规律,在Gleeble-1500D热模拟试验机上进行了单轴压缩实验,实验选取的变形温度为900~1200℃、应变速率为0.01~1 s^(-1)、真应变为0.693。整理实验数据并绘制得到了30Cr1MoV钢... 详细信息

为了研究高中压转子用30Cr1MoV钢在热变形过程中的动态再结晶规律,在Gleeble-1500D热模拟试验机上进行了单轴压缩实验,实验选取的变形温度为900~1200℃、应变速率为0.01~1 s^(-1)、真应变为0.693。整理实验数据并绘制得到了30Cr1MoV钢的真应力-真应变曲线,采集曲线上的特征值,通过线性拟合计算得到了各项材料系数,建立了30Cr1MoV钢的本构方程和动态再结晶动力学模型。从试样的金相照片中测得了平均晶粒尺寸,建立了动态再结晶晶粒尺寸模型,并将其导入Deform-3D软件材料库中,进行单轴压缩成形模拟。模拟结果与实验结果的误差控制在8%以内,验证了动态再结晶模型的准确性,说明在后续的工艺实验中,借助该模型可以有效预测30Cr1MoV钢的动态再结晶行为。

关键词： 30Cr1MoV钢动态再结晶变形温度晶粒尺寸微观组织

A Multiple Negotiations Model Considering Interdependence between Discrete Issues Across Negotiations

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Journal of Systems Science and Systems Engineering 2021年第4期30卷 417-432页

作者： Lei Niu Litian Huang jinhua zhao Xinguo Yu Central China Normal University Wollongong Joint Institute Central China Normal UniversityWuhan430000China School of Economics and Management Wuhan UniversityWuhan430000China National Engineering Research Center for E-Learning&Central China Normal University Wollongong Joint Institute Central China Normal UniversityWuhan430000China

The research of multiple negotiations considering issue interdependence across negotiations is considered as a complex research topic in agent negotiation. In the multiple negotiations scenario, an agent conducts multiple negotiations with opponents for different negotiation goals, and issues in a single negotiation might be interdependent with issues in other negotiations. Moreover, the utility functions involved in multiple negotiations might be nonlinear, e.g., the issues involved in multiple negotiations are discrete. Considering this research problem, the current work may not well handle multiple interdependent negotiations with complex utility functions, where issues involved in utility functions are discrete. Regarding utility functions involving discrete issues, an agent may not find an offer exactly satisfying its expected utility during the negotiation process. Furthermore, as sub-offers on issues in every single negotiation might be restricted by the interdependence relationships with issues in other negotiations, it is even harder for the agent to find an offer satisfying the expected utility and all involved issue interdependence at the same time, leading to a high failure rate of processing multiple negotiations as a final outcome. To resolve this challenge, this paper presents a negotiation model for multiple negotiations, where interdependence exists between discrete issues across multiple negotiations. By introducing the formal definition of “interdependence between discrete issues across negotiations”, the proposed negotiation model applies the multiple alternating offers protocol, the clustered negotiation procedure and the proposed negotiation strategy to handle multiple interdependent negotiations with discrete issues. In the proposed strategy, the “tolerance value” is introduced as an agent’s consideration to balance between the overall negotiation goal and the negotiation outcomes. The experimental results show that, 1) the proposed model well

关键词： multiple negotiations discrete issues interdependence relationships nonlinear utility functions

非^(18)F-FDG PET分子显像在淋巴瘤中的应用进展

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国际放射医学核医学杂志 2024年第3期48卷 198-203页

作者：廖思锶赵晋华上海交通大学医学院附属第一人民医院核医学科上海200080

淋巴瘤是一种起源于淋巴结和淋巴组织的免疫系统恶性肿瘤,具有起病隐匿、侵袭性强等特点,是我国发病率增速最快的肿瘤之一。目前,^(18)F-FDG PET/CT已经成为恶性淋巴瘤初始分期、再分期、早期治疗反应及疗效评估、预后预测与随访的重要... 详细信息

淋巴瘤是一种起源于淋巴结和淋巴组织的免疫系统恶性肿瘤,具有起病隐匿、侵袭性强等特点,是我国发病率增速最快的肿瘤之一。目前,^(18)F-FDG PET/CT已经成为恶性淋巴瘤初始分期、再分期、早期治疗反应及疗效评估、预后预测与随访的重要影像技术。由于淋巴瘤的异质性,如侵袭性、组织来源、免疫表型、病程阶段、不同人群治疗反应等的差异,非^(18)F-FDG PET分子显像技术在一些特定类型淋巴瘤的靶向诊疗中表现出较^(18)F-FDG PET/CT更明显的优势。笔者聚焦于非^(18)F-FDG PET分子显像在淋巴瘤中的研究进展,比较了非^(18)F-FDG显像剂与传统显像剂^(18)F-FDG在淋巴瘤诊疗过程中的异同、优势与不足、应用特色和发展潜能,期望为淋巴瘤特异性靶向诊疗和个性化精准医疗提供新的思路和方法。

关键词：淋巴瘤氟脱氧葡萄糖F18 正电子发射断层显像术分子显像靶向诊疗

深入推进 PET/CT 显像临床指南在淋巴瘤治疗决策中的应用

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国际放射医学核医学杂志 2024年第3期48卷 137-140页

作者：乔文礼赵晋华上海交通大学医学院附属第一人民医院核医学科上海200080

《淋巴瘤18F-FDG PET/CT及PET/MR显像临床应用指南(2021版)》已广泛应用于淋巴瘤诊断、治疗等方面,尤其是治疗决策和预后评估。本期重点号以PET/CT显像在淋巴瘤中的应用为主题,分析了PET/CT在淋巴瘤分期、鉴别诊断、疗效评价与预后评估... 详细信息

《淋巴瘤18F-FDG PET/CT及PET/MR显像临床应用指南(2021版)》已广泛应用于淋巴瘤诊断、治疗等方面,尤其是治疗决策和预后评估。本期重点号以PET/CT显像在淋巴瘤中的应用为主题,分析了PET/CT在淋巴瘤分期、鉴别诊断、疗效评价与预后评估中的价值以及人工智能与非18F-FDG显像剂的应用价值。PET/CT显像的多参数分析、影像纹理特征解析、非18F-FDG显像剂的应用能够为淋巴瘤的诊断和治疗提供丰富信息。

关键词：淋巴瘤正电子发射断层显像术体层摄影术,X线计算机预后治疗决策

Environmental Economics and Policy： Two Way Learning between China and the Rest of the World

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Frontiers of Economics in China-Selected Publications from Chinese Universities 2014年第1期9卷 1-5页

作者： jinhua zhao Department Of Economics Department of Agriculture Food and Resource Economics Environmental Science and Policy Program Michigan State University East Lansing MI 48824 USA Institute for Advanced Studies Shanghai University of Finance and Economics Shanghai200433 China

Environmental degradation poses perhaps the greatest challenge to present day China as it continues to improve the living standard and general welfare of its citizens. According to a recent Pew Research Center survey （Pew Research Center, 2013）, air pollution and water pollution are among the top five public concems in China, coming after inflation, inequality and corruption. Water pollution is also among the top five issues for which the public concern has increased the most during the past five years, coming after food safety, medicine and manufactured goods, and old age insurance. Yet, despite public concerns and increased abatement expenditures, major pollution levels have been increasing rather than decreasing. For many days during 2013, large parts of eastern China have suffered from blanketing thick smog caused by PM2.5 pollution, with airports and freeways shut down and schools closed.

关键词： LAND use AIR quality ENVIRONMENTAL management CHINA

全自动在线固相萃取-液相色谱串联质谱法快速测定地表水中痕量甲基对硫磷

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环境化学 2024年第7期43卷 2504-2507页

作者：任颖俊彭君赵锦华刘立平李超群梁锋湖南省地质实验测试中心长沙410007

建立了全自动化在线固相萃取-液相色谱串联质谱法快速、准确测定地表水中痕量甲基对硫磷的方法.水样经在线富集、色谱柱分离后,梯度洗脱,采用电喷雾离子源正离子多反应监测模式,内标法定量.通过对离子源参数、水相洗脱溶剂、有机相洗脱... 详细信息

建立了全自动化在线固相萃取-液相色谱串联质谱法快速、准确测定地表水中痕量甲基对硫磷的方法.水样经在线富集、色谱柱分离后,梯度洗脱,采用电喷雾离子源正离子多反应监测模式,内标法定量.通过对离子源参数、水相洗脱溶剂、有机相洗脱溶剂、洗脱溶剂初始比例进行优化试验,甲基对硫磷的灵敏度显著提升,峰型更好.该方法在质量浓度5—1000 ng·L^(-1)范围内线性关系良好(相关系数R^(2)≥0.998).添加回收试验结果表明,方法检出限为4 ng·L^(-1),方法定量限为16 ng·L^(-1),在40、100、500 ng·L^(-1)的3个添加水平下,平均回收率为90.1%—97.8%,相对标准偏差为1.7%—3.5%。应用于实际地表水样品测定,结果均未检出.该方法便捷、高效,可实现高通量测定地表水中痕量甲基对硫磷.

关键词：全自动在线固相萃取液相色谱串联质谱甲基对硫磷

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The Value of Clean Air in China： Evidence from Beijing and Shanghai

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Frontiers of Economics in China-Selected Publications from Chinese Universities 2014年第1期9卷 109-137页

作者： Jijun Tan jinhua zhao Research Institute for Economics and Management Southwest University of Finance andEconomics Chengdu 610074 China Department of Economics Department of Agriculture Food and Resource Economics Environmental Science and Policy Program Michigan State University East Lansing MI48824 USA Institute for Advanced Studies Shanghai University of Finance and Economics Shanghai200433 China

We estimate the willingness to pay （WTP） of Beijing and Shanghai residents for improving the air quality of the two cities from their levels prior to the 2008 Beijing Olympic Games to the level achieved during the Olympics. The data are obtained from a contingent valuation study conducted through face-to-face interviews in June 2008 in Beijing and Shanghai prior to the Beijing Olympics, during which time there was intensive debate about Beijing＇s air quality. Residents in both cities are willing to pay more when they are more exposed to air pollution, when their disposable income increases, and when they have stronger beliefs that public opinion plays an important role in government policy making. Beijing residents are willing to pay more than Shanghai residents, due possibly to Beijing＇s poorer air quality. Overall, aggregate WTP for air quality improvement accounts for about 0.53% of the 2008 GDP in Beijing and 0.22% of the 2008 GDP in Shanghai.

关键词： contingent valuation Beijing Olympic Games air quality