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Journal of Geoscience and Environment Protection 2018年第11期6卷 67-76页

作者： Junfeng Wu Langrun Song Qian feng jingyang Luo Zhaoxia Xue Academy of Environmental Planning & Design Co. Ltd. Nanjing University Nanjing China Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes Ministry of Education Hohai University Nanjing China College of Environment Hohai University Nanjing China

The non-point source pollution posed great risks to the urban water environment which has aroused great concerns. Artificial rapid infiltration systems have been widely used in sewage treatment, which have great environmental and economic values. This study investigated the potential of utilizing artificial rapid infiltration systems on the reduction of urban non-point source pollution. The obtained results showed that the components and composition of artificial soils were vital to the operational performance. The mixture of natural soil, coarse sand and zeolite was ideal for the construction of artificial soils. The permeability coefficient of soils could be improved to 0.166 cm/min at the optimized ratio of 1:1:0.05 (natural soil, coarse sand and zeolite). Also, high removal efficiency for the typical pollutants in rain runoffs (i.e. COD, NH4+-N, TN and TP) could be simultaneous obtained which was above 74% in the artificial rapid infiltration systems. The results demonstrated the effectiveness on the reduction of urban non-point pollution by optimized artificial rapid infiltration system.

关键词： Non-Point Source Pollution Artificial Rapid Infiltration System Permeability Coefficient Zeolite Pollutants Removal Efficiency

CTCs Detection and Whole-exome Sequencing Might Be Used to Differentiate Benign and Malignant Pulmonary Nodules

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中国肺癌杂志 2023年第6期26卷 449-460页

作者： Changdan XU Xiaohong XU Weipeng SHAO Hongliang SUN Xiaohong LIU Hongxiang feng Xianbo ZUO jingyang GAO Guohui WANG Xiongtao YANG Runchuan GU Shutong GE Shijie WANG Liwei GAO Guangying ZHU Department of Radiation Oncology Peking University China-Japan Friendship School of Clinical MedicineBeijing 100029China Department of Radiation Oncology Zhongshan HospitalFudan UniversityShanghai 200032China Department of Thoracic Surgery China-Japan Friendship HospitalBeijing 100029China Department of Radiology China-Japan Friendship HospitalBeijing 100029China Department of Information Science and Technology Beijing University of Chemical TechnologyBeijing 100029China Department of Dermatology China-Japan Friendship HospitalBeijing 100029China Department of Pharmacy China-Japan Friendship HospitalBeijing 100029China Department of Radiation Oncology Tianjin First Central HospitalTianjin 300070China Department of Oncology Beijing Changping District HospitalBeijing 102200China Faculty of Medicine Lund University Lund SE-22100Sweden Department of Radiation Oncology China-Japan Friendship HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100029China Department of Radiation Oncology Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China

Background and objective Low-density computed tomography(LDCT)improved early lung cancer diagnosis but introduces an excess of false-positive pulmonary nodules ***,accurate diagnosis of early-stage lung cancer remains *** purpose of the study was to assess the feasibility of using circulating tumour cells(CTCs)to differentiate malignant from benign pulmonary *** and methods 122 patients with suspected malignant pulmonary nodules detected on chest CT in preparation for surgery were prospectively *** blood samples were collected before surgery,and CTCs were identified upon isolation by size of epithelial tumour cells and morphological *** capture microdissection,MALBAC amplification,and whole-exome sequencing were performed on 8 *** diagnostic efficacy of CTCs counting,and the genomic variation profile of benign and malignant CTCs samples were *** Using 2.5 cells/5 m L as the cut-off value,the area under the receiver operating characteristic curve was of 0.651(95%confidence interval:0.538-0.764),with a sensitivity and specificity of 0.526 and 0.800,respectively,and positive and negative predictive values of 91.1%and 30.3%,*** sequence variations differences in DNA damage repair-related and driver genes were observed in benign and malignant ***53 mutations were identified in CTCs of four malignant cases;in particular,g.7578115T>C,g.7578645C>T,and g.7579472G>C were exclusively detected in all four malignant *** CTCs play an ancillary role in the diagnosis of pulmonary ***53 mutations in CTCs might be used to identify benign and malignant pulmonary nodules.

关键词： Chest computed tomography Circulating tumour cells Lung nodule TP53 Whole-exome sequencing

Importance of Monitor and Control on New-Emerging Pollutants in Conventional Wastewater Treatment Plants

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Journal of Geoscience and Environment Protection 2018年第1期6卷 55-58页

作者： jingyang Luo Qin Zhang Jiashun Cao Fang Fang Qian feng Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes Ministry of Education Nanjing China College of Environment Hohai University Nanjing China Wentian College Hohai University Ma’anshan China

The wide occurrence of new-emerging pollutants and their potential environmental and ecological risks have recently caused great public concerns. The paper firstly put forward the severe problem. Then the possible main reasons were analyzed which might attribute to both the inefficient removal of wastewater treatment plants with conventional technology and ignorance of the monitor and control of new-emerging pollutants in the effluents. Also, the complexity and extreme high costs may also make the organizations sidestep the problem. Finally, possible strategies to deal with the problems were proposed. The upgrade of wastewater treatment plants was important and urgent.

关键词： New-Emerging Pollutants Environmental and Ecological Risks Inefficient Removal Wastewater Treatment Plants Upgrade

Enhancing maize's nitrogen-fixing potential through ZmSBT3, a gene suppressing mucilage secretion∞

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Journal of Integrative Plant Biology 2023年第12期65卷 2645-2659页

作者： jingyang Gao Peijiang feng Jingli Zhang Chaopei Dong Zhao Wang Mingxiang Chen Zhongliang Yu Bowen Zhao Xin Hou Huijuan Wang Zhaokun Wu Razia Sultana Jemim Haidong Yu Doudou Sun Pei Jing Jiafa Chen Weibin Song Xuecai Zhang Zijian Zhou Jianyu Wu College of Agronomy State Key Laboratory of Wheat and Maize Crop ScienceHenan Agricultural UniversityZhengzhou 450002China College of Life Sciences Henan Agricultural UniversityZhengzhou 450002China State Key Laboratory of Plant Physiology and Biochemistry National Maize Improvement CenterCollege of Agronomy and BiotechnologyChina Agricultural UniversityBeijing 100193China International Maize and Wheat Improvement Center(CIMMYT) El BatanTexcoco 56237Mexico

Maize(Zea mays)requires substantial amounts of nitrogen,posing a challenge for its *** work discovered that some ancient Mexican maize landraces harbored diazotrophic bacteria in mucilage secreted by their aerial *** see if this trait is retained in modern maize,we conducted a field study of aerial root mucilage(ARM)in 258 inbred *** observed that ARM secretion is common in modern maize,but the amount significantly varies,and only a few lines have retained the nitrogen‐fixing traits found in ancient *** mucilage of the high‐ARM inbred line HN5‐724 had high nitrogen‐fixing enzyme activity and abundant diazotrophic *** genome‐wide association study identified 17 candidate genes associated with ARM across three *** of one candidate gene,the subtilase family gene ZmSBT3,confirmed that it negatively regulates ARM ***,the ZmSBT3 knockout lines had increased biomass and total nitrogen accumulation under nitrogen‐free culture *** ARM was associated with three ZmSBT3 haplotypes that were gradually lost during maize domestication,being retained in only a few modern inbred lines such as HN5‐*** summary,our results identify ZmSBT3 as a potential tool for enhancing ARM,and thus nitrogen fixation,in maize.

关键词： maize aerial root mucilage nitrogen‐fixing ZmSBT3 GWAS gene cloning Diazotroph

Ru对镍基单晶热暴露组织演变及持久性能的影响

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稀有金属材料与工程 2011年第12期40卷 2111-2116页

作者：陈晶阳胡聘聘冯强曹腊梅孙祖庆北京科技大学新金属材料国家重点实验室北京100083 北京航空材料研究院先进高温结构材料重点实验室北京100095 北京科技大学国家材料服役安全科学中心北京100083

对比研究了不含Ru的USTB-F7及添加2.5wt%Ru的USTB-F8两种镍基单晶高温合金的组织稳定性和持久性能。标准热处理与1100℃长期热暴露组织研究表明:合金USTB-F7中γ′相形貌介于球形和立方形之间,属中间态形貌;热暴露2000h后,其形貌仍保持... 详细信息

对比研究了不含Ru的USTB-F7及添加2.5wt%Ru的USTB-F8两种镍基单晶高温合金的组织稳定性和持久性能。标准热处理与1100℃长期热暴露组织研究表明:合金USTB-F7中γ′相形貌介于球形和立方形之间,属中间态形貌;热暴露2000h后,其形貌仍保持稳定,仅发生粗化而未发生筏排化。Ru的添加使Re元素在γ/γ′中的分配比增大,提高了合金USTB-F8的γ/γ′点阵错配度和γ′相的立方度,从而加速了长期热暴露过程中的筏排化进程,经2000h热暴露发生了明显的筏排化现象。同时,合金USTB-F7热暴露700h后在枝晶干处析出了富集Re、W和Cr元素的TCP相,Ru的加入有效地抑制了TCP相的析出,合金USTB-F8直至2000h仍未析出TCP相。1100℃/140MPa持久性能测试表明,Ru显著提高合金的持久寿命,这与Ru增加合金中的γ′相体积分数和γ/γ′点阵错配度,促进筏排组织的形成,并减小时效组织中的γ通道宽度有关。

关键词：高温合金 Ru 错配度组织稳定性持久寿命

一测多评法同时测定清开灵片剂和颗粒剂中6个成分

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中华中医药学刊 2024年第3期42卷 214-220页

作者：周菁杨张玉峰刘蕙宁卢周琪林星宇朱青秀韩丰詹淑玉浙江中医药大学药学院浙江杭州311403 嘉兴学院医学院浙江嘉兴314001 嘉兴学院附属医院浙江嘉兴314001

目的建立测定清开灵制剂中6个成分含量的一测多评(quantitative analysis of multi-components with a single-marker, QAMS)方法。方法采用高效液相色谱(HPLC)法,以黄芩苷为内参物,建立与其他5个成分(R,S)-告依春、绿原酸、栀子苷、... 详细信息

目的建立测定清开灵制剂中6个成分含量的一测多评(quantitative analysis of multi-components with a single-marker, QAMS)方法。方法采用高效液相色谱(HPLC)法,以黄芩苷为内参物,建立与其他5个成分(R,S)-告依春、绿原酸、栀子苷、胆酸和猪去氧胆酸的相对校正因子(fk/s),并对fk/s进行耐用性考察。分别采用外标法和QAMS法测定6批清开灵片剂和4批清开灵颗粒剂中6个成分含量,比较两者的差异。结果各个成分fk/s的重复性良好(RSD<5%);两种方法测定的含量结果差异无统计学意义;6个成分在片剂中的含量高于颗粒剂,同一厂家不同批号的片剂间成分含量存在差异。结论所建立的一测多评法结果准确可靠,可用于清开灵制剂的多成分含量检测,为清开灵制剂的质量控制提供方法参考。

关键词：清开灵片剂清开灵颗粒剂黄芩苷一测多评

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用于心脏修复与再生的可注射水凝胶的研究进展

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临床心血管病杂志 2021年第3期37卷 204-209页

作者：樊景阳李苏雷曹丰青岛大学医学部山东青岛266071 解放军总医院第二医学中心解放军总医院国家老年疾病临床医学研究中心

心肌梗死是威胁人类健康的重大疾病之一。心肌梗死后大量心肌细胞发生坏死并形成瘢痕,最终导致心力衰竭。目前,治疗终末期心力衰竭的方法包括药物治疗、左心室辅助装置植入和心脏移植,但这些方法都存在一定局限性。细胞移植进行心脏修... 详细信息

心肌梗死是威胁人类健康的重大疾病之一。心肌梗死后大量心肌细胞发生坏死并形成瘢痕,最终导致心力衰竭。目前,治疗终末期心力衰竭的方法包括药物治疗、左心室辅助装置植入和心脏移植,但这些方法都存在一定局限性。细胞移植进行心脏修复与再生是一种有前景的心力衰竭治疗方法,但移植后细胞的低滞留率和低存活率大大限制了其在临床的推广应用。可注射水凝胶可以作为移植细胞的载体,通过微创的方式进行心肌注射改善细胞的植入和存活,使其在心脏组织工程中更具吸引力。本文拟对多种可注射水凝胶的特点及最新研究进展进行综述。

关键词：组织工程水凝胶心肌梗死心力衰竭细胞移植

Evaluation of Lipid Metabolism Regulation in the Treatment Efficacy of Elderly Patients with Prostate Cancer

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Proceedings of Anticancer Research 2020年第1期4卷 1-4页

作者： Deqiang Gu Quansuo Zhang Yanqiao Zhang Song Li jingyang Guo Wentao Wang Tao Ma Wei Zhang feng An Department of Urology Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Rongcheng County Hospital Baoding 071000Hebei ProvinceChina

Objective:To study the characteristics of elderly patients with prostate cancer,and to analyze the effect of lipid metabolism regulation on patients’***:60 elderly patients with prostate cancer were randomly *** the observation group,collected the data,adjusted with lipid metabolism and treated *** the control group,collected the data and treated ***:PSA,TG,TC,the total effective rate and adverse reactions were significantly improved after 12 months of treatment(P<0.05).Conclusion:The effect of lipid metabolism regulation on elderly patients with prostate cancer treatment is satisfactory.

关键词： Elderly Prostate cancer Lipid metabolism regulation

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基于图像分割的稠密立体匹配算法

光学学报 2019年第3期39卷 240-248页

作者：马瑞浩朱枫吴清潇鲁荣荣魏景阳中国科学院沈阳自动化研究所辽宁沈阳110016 东北大学信息科学与工程学院辽宁沈阳110819 中国科学院光电信息处理重点实验室辽宁沈阳110016

提出一种基于图像分割的稠密立体匹配算法,该算法将灰度-梯度算法与零均值归一化互相关(ZNCC)算法相结合生成匹配代价,利用SLIC(Simple Liner Iterative Cluster)算法对图像进行分割,基于视差图和超像素更新了匹配代价。在视差后处理阶... 详细信息

提出一种基于图像分割的稠密立体匹配算法,该算法将灰度-梯度算法与零均值归一化互相关(ZNCC)算法相结合生成匹配代价,利用SLIC(Simple Liner Iterative Cluster)算法对图像进行分割,基于视差图和超像素更新了匹配代价。在视差后处理阶段,基于左右一致性检验(LRC)、孔洞填充和十字交叉自适应窗口加权中值滤波的方法减小视差图的误匹配率。利用Middlebury数据集的4组图像进行测试,测试结果表明,平均误匹配率为4.99%。

关键词：机器视觉立体匹配算法匹配代价计算方法融合十字交叉自适应窗口加权中值滤波

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车辆液压动力转向油泵台架试验研究

汽车技术 2010年第8期 44-48页

作者：蔡锋颜尧刘旌扬一汽海马汽车有限公司国家机动车质量监督检验中心

针对某液压动力转向油泵(叶片泵)建立了数学模型,分析了其流量、压力及转速间的耦合关系,并对比分析了不同企业标准的差异,提出了增加压力/流量动态特性试验的必要性。通过试验台架进行了流量/压力试验,结果表明,试验曲线与所建油泵数... 详细信息

针对某液压动力转向油泵(叶片泵)建立了数学模型,分析了其流量、压力及转速间的耦合关系,并对比分析了不同企业标准的差异,提出了增加压力/流量动态特性试验的必要性。通过试验台架进行了流量/压力试验,结果表明,试验曲线与所建油泵数学模型吻合较好,能够为转向油泵和模型优化及转向系统匹配提供数据参考。

关键词：液压动力转向油泵数学模型流量压力特性