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Characterizing and Understanding Development of Social Computing Through DBLP: A Data-Driven Analysis

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Journal of Social Computing 2022年第4期3卷 287-302页

作者： Jiaqi Wu Bodian Ye Qingyuan Gong Atte Oksanen Cong Li jingjing qu Felicia F.Tian Xiang Li Yang Chen the Shanghai Key Lab of Intelligent Information Processing the School of Computer ScienceFudan UniversityShanghai 200438China the Faculty of Social Sciences Tampere UniversityTampere 33100Finland School of Information Science and Technology Fudan UniversityShanghai 200438China Shanghai Artificial Intelligence Laboratory Shanghai 200232China. School of Social Development and Public Policy Fudan UniversityShanghai 200433China. Institute of Complex Networks and Intelligent Systems Shanghai Research Institute for Intelligent Autonomous SystemsTongji UniversityShanghai 200092China.

During the past decades,the term“social computing”has become a promising interdisciplinary area in the intersection of computer science and social science.In this work,we conduct a data-driven study to understand the development of social computing using the data collected from Digital Bibliography and Library Project(DBLP),a representative computer science bibliography website.We have observed a series of trends in the development of social computing,including the evolution of the number of publications,popular keywords,top venues,international collaborations,and research topics.Our findings will be helpful for researchers and practitioners working in relevant fields.

关键词： social computing Digital Bibliography and Library Project(DBLP) bibliometric evolution visualization

Tumor organoids:synergistic applications,current challenges,and future prospects in cancer therapy

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Cancer Communications 2021年第12期41卷 1331-1353页

作者： jingjing qu Farhin Shaheed Kalyani Li Liu Tianli Cheng Lijun Chen Department of Respiratory Disease Thoracic Disease CenterThe First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhouZhejiang 310003P.R.China Lung Cancer and Gastroenterology Department Hunan Cancer HospitalAffiliated Tumor Hospital of Xiangya Medical SchoolCentral South UniversityChangshaHunan 410008P.R.China Thoracic Medicine Department 1 Hunan Cancer HospitalAffiliated Tumor Hospital of Xiangya Medical SchoolCentral South UniversityChangshaHunan 410008P.R.China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhouZhejiang 310003P.R.China

Patient-derived cancer cells(PDCs)and patient-derived xenografts(PDXs)are often used as tumor models,but have many shortcomings.PDCs not only lack diversity in terms of cell type,spatial organization,and microenvironment but also have adverse effects in stem cell cultures,whereas PDX are expensive with a low transplantation success rate and require a long culture time.In recent years,advances in three-dimensional(3D)organoid culture technology have led to the development of novel physiological systems that model the tissues of origin more precisely than traditional culture methods.Patient-derived cancer organoids bridge the conventional gaps in PDC and PDX models and closely reflect the pathophysiological features of natural tumorigenesis and metastasis,and have led to new patient-specific drug screening techniques,development of individualized treatment regimens,and discovery of prognostic biomarkers and mechanisms of resistance.Synergistic combinations of cancer organoids with other technologies,for example,organ-on-a-chip,3D bio-printing,and CRISPR-Cas9-mediated homology-independent organoid transgenesis,and with treatments, such as immunotherapy, have been useful in overcoming their limitations and led to the development of more suitable model systems that recapitulate the complex stroma of cancer, inter-organ and intra-organ communications,and potentially multiorgan metastasis. In this review, we discuss various methods for the creation of organ-specific cancer organoids and summarize organspecific advances and applications, synergistic technologies, and treatments aswell as current limitations and future prospects for cancer organoids. Furtheradvances will bring this novel 3D organoid culture technique closer to clinicalpractice in the future.

关键词： cancer organoids drug screening personalized medicine prognostic biomarker organ-on-achip 3D bio-printing tumor microenvironment cancer stroma

Microstructures and microwave dielectric properties of (Ba1-xSrx)4(Sm0.4Nd0.6)28/3Ti18O54 solid solutions

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Journal of Advanced Ceramics 2017年第1期6卷 50-58页

作者： Xianpei HUANG Xinyu LIU Fei LIU Changlai YUAN jingjing qu Jiwen XU Changrong ZHOU Guohua CHEN School of Material Science and Engineering Guilin University of Electronic Technology Guilin 541004 China School of Mechanical and Electrical Engineering Guilin University of Electronic Technology Guilin 541004 China School of Material Science and Engineering Guilin University of Electronic Technology Guilin 541004 China Guangxi Key Laboratory of Information Materials Guilin University of Electronic Technology Guilin 541004 China Department of Information Engineering Guilin University of Aerospace Technology Guilin 541004 China

(Ba 1x Sr x )4(Sm0.4 Nd 0.6)28/3 Ti 18 O 54(x = 0.02， 0.04， 0.06， 0.08， 0.1 ) 稳固的解决方案被准备由常规固态反应过程。它被发现那(Ba 1x Sr x )4(Sm0.4 Nd 0.6)28/3 Ti 18 O 54 陶艺充分由 BaSm 2 Ti 4 O 12 和乐队 2 ... 详细信息

(Ba 1x Sr x )4(Sm0.4 Nd 0.6)28/3 Ti 18 O 54(x = 0.02， 0.04， 0.06， 0.08， 0.1 ) 稳固的解决方案被准备由常规固态反应过程。它被发现那(Ba 1x Sr x )4(Sm0.4 Nd 0.6)28/3 Ti 18 O 54 陶艺充分由 BaSm 2 Ti 4 O 12 和乐队 2 Ti 5 为所有作文的 O 14 阶段。增加的 x 价值(0.02 x 0.1 ) 在((Ba 1x Sr x )4(Sm0.4 Nd 0.6)28/3 Ti 18 O 54 陶艺不能仅仅获得高

关键词：钨铜类型高介电常数微波电介质性质

高校非机械类工科专业“工程制图”课程教学改革探讨

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科教导刊 2024年第1期 124-126页

作者：刘飞曾福生屈婧婧桂林电子科技大学广西桂林541004 桂林航天工业学院广西桂林541004

鉴于新时代“新工科”建设对人才培养的新要求,针对非机械类工科专业在“工程制图”教学过程中存在的一系列亟须解决的问题,文章通过分析非机械类工科专业“工程制图”课程教学现状,基于教学内容、所支撑的课程目标与毕业要求指标点,在... 详细信息

鉴于新时代“新工科”建设对人才培养的新要求,针对非机械类工科专业在“工程制图”教学过程中存在的一系列亟须解决的问题,文章通过分析非机械类工科专业“工程制图”课程教学现状,基于教学内容、所支撑的课程目标与毕业要求指标点,在教学内容、教学方式和考核方式等方面提出了一系列教学改进措施的思路与方法,以达到提升学生学习效果的目标,望为“工程制图”教学课程发展提供启发。

关键词：人才培养工程制图教学现状教学改革

森林火灾救援直升机吊桶灭火任务调度优化研究

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消防科学与技术 2024年第4期43卷 535-540页

作者：徐浩瞿菁菁王明惠朱新平中国民用航空飞行学院四川广汉618307

鉴于森林火灾突发性强、处置困难等特点及火灾救援中直升机任务调度效率有待提高的现状,为降低森林火灾造成的损失,研究直升机吊桶灭火任务调度优化的方法。结合火场面积、火情状况、救援力量等因素,建立火场空域栅格模型。针对森林火... 详细信息

鉴于森林火灾突发性强、处置困难等特点及火灾救援中直升机任务调度效率有待提高的现状,为降低森林火灾造成的损失,研究直升机吊桶灭火任务调度优化的方法。结合火场面积、火情状况、救援力量等因素,建立火场空域栅格模型。针对森林火灾场景中火场动态变化的情况,提出一种基于深度强化学习(DQN)的动态任务调度优化方法,该方法通过对起火栅格的燃烧时间约束、灭火所需水量等属性进行实时量化,不断更新全局环境,形成动态决策依据,生成任务调度方案,提升直升机吊桶灭火的效率。仿真结果表明,与传统算法中表现较好的贪婪算法相比,本文方法能在火场动态变化的场景下,降低了13.9%的火灾损失率,有效减少了森林火灾造成的资源损失。

关键词：任务调度深度强化学习应急救援动态决策直升机吊桶

Development of a Gamma Spectroscopy Detector Based on SiPMs and 1" Ce:GAGG Scintillator

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Journal of Applied Mathematics and Physics 2023年第7期11卷 2156-2164页

作者： Qiang Wang Zetao Zhang Yuchong Ding Xuanhou Hu Xiong Xiao Biao Wang jingjing qu Qianyin Wan Yang Xu 26th Research Institute China Electronics Technology Group Corporation Chongqing China Beijing Engineering Research Center of Radiographic Techniques and Equipment Institute of High Energy Physics Chinese Academy of Sciences Beijing China State Key Laboratory of NBC Projection for Civilian Beijing China State Nuclear Security Technology Center Beijing China

In the field of nuclear radiation detection, sodium iodide (NaI(Tl)) and lanthanum bromide (LaBr3) are the primary scintillation crystals used for energy spectrum detectors. Furthermore, energy spectrum detectors based on gadolinium gallium aluminum garnet (Ce:GAGG) scintillation crystals are minor. In this work, a 1-inch Ce:GAGG and Silicon Photomultipliers (SiPMs) are employed to construct a detector, and the coupled medium was silicone oil. An optimal SiPMs quantity scheme for the energy resolution was determined by varying the number of SiPMs coupled to Ce:GAGG and studying the effect of the different number of SiPMs on the energy resolution of the detector. Energy-resolution contrast experiments between Ce:GAGG and NaI(Tl) were performed using this scheme. The experimental results demonstrate that increasing the number of SiPMs enhances the energy resolution of the detector significantly. Notably, the energy resolution of the Ce:GAGG detector is comparable to that of the NaI(Tl) detector. Additionally, both detectors exhibit an energy linearity exceeding 99.9%. .

关键词： Ce:GAGG Gamma Spectroscopy Detector SiPMs Energy Resolution

Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

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Frontiers of Medicine 2020年第5期14卷 664-673页

作者： Lingling Tang Yingan Jiang Mengfei Zhu Lijun Chen Xiaoyang Zhou Chenliang Zhou Peng Ye Xiaobei Chen Baohong Wang Zhenyu Xu Qiang Zhang Xiaowei Xu Hainv Gao Xiaojun Wu Dong Li Wanli Jiang jingjing qu Charlie Xiang Lanjuan Li The Shulan(Hangzhou)Hospital Affiliated to Shulan International Medical CollegeZhejiang Shuren UniversityHangzhou 310022China Department of Infectious Diseases Renmin Hospital of Wuhan UniversityWuhan 430060China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003China Innovative Precision Medicine(IPM)Group Hangzhou 311215China

The coronavirus disease 2019(COVID-19)caused by SARS-CoV-2 was identified in December 2019.The symptoms include fever,cough,dyspnea,early symptom of sputum,and acute respiratory distress syndrome(ARDS).Mesenchymal stem cell(MSC)therapy is the immediate treatment used for patients with severe cases of COVID-19.Herein,we describe two confirmed cases of COVID-19 in Wuhan to explore the role of MSC in the treatment of COVID-19.MSC transplantation increases the immune indicators(including CD4 and lymphocytes)and decreases the inflammation indicators(interleukin-6 and C-reactive protein).High-flow nasal cannula can be used as an initial support strategy for patients with ARDS.With MSC transplantation,the fracrion of inspired O2(Fi02)of the two patients gradually decreased while the oxygen saturation(Sa02)and partial pressure of oxygen(P02)improved.Additionally,the patients9 chest computed tomography showed that bilateral lung exudate lesions were adsorbed after MSC infusion.Results indicated that MSC transplantation provides clinical data on the treatment of COVID-19 and may serve as an alternative method for treating COVID-19,particularly in patients with ARDS.

关键词： coronavirus disease 2019(COVID-19) mesenchymal stem cell acute respiratory distress syndrome stem cell therapeutics

术前微信视频宣教在结直肠癌患者术后加速康复中的应用

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中西医结合护理（中英文） 2024年第1期10卷 103-105页

作者：陆信燕瞿晶晶赵焕利扬州大学第四临床医学院南通瑞慈医院江苏南通226010

目的探讨术前微信视频宣教应用于结直肠癌患者术后加速康复护理中的效果。方法选择2019年10月至2021年10月南通瑞慈医院收治的126例行结直肠癌手术的患者为研究对象,并进行回顾性分析。对照组行常规干预,观察组在此基础上应用术前微信... 详细信息

目的探讨术前微信视频宣教应用于结直肠癌患者术后加速康复护理中的效果。方法选择2019年10月至2021年10月南通瑞慈医院收治的126例行结直肠癌手术的患者为研究对象,并进行回顾性分析。对照组行常规干预,观察组在此基础上应用术前微信视频宣教干预。对比2组的术后恢复指标、一般自我效能感、生活质量及不良反应情况。结果观察组的首次排气时间、首次进食时间、首次下床活动时间和导尿管拔出时间均早于对照组,不良反应总发生率低于对照组(P均<0.05)。观察组在出院3个月后的一般自我效能感量表评分,以及肿瘤患者生活质量自评量表各项评分均高于对照组(P均<0.05)。结论将术前微信视频宣教应用于行结直肠癌术后患者,可促进其术后康复,提升其一般自我效能感,改善其生活质量,降低术后不良反应发生率。

关键词：结直肠癌术前微信视频宣教加速康复护理一般自我效能感生活质量

高斯滤波增强技术融合最大类间方差法在医学影像诊断中的应用研究

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中国数字医学 2024年第5期19卷 72-77页

作者：李泽宇何萍贺奇徐佳鼎谷辛稼瞿晶晶上海申康医院发展中心上海200041 上海计算技术研究所上海大学上海人工智能实验室

为了进一步提高肺部医学影像辅助诊断的准确性,提出一种高斯滤波增强技术融合最大类间方差法对肺部CT影像进行分割和计算病变面积占比的算法。首先对原始图像采用高斯低通滤波运算去除噪声和杂质并使用MSVSR提高图像质量,然后通过最大... 详细信息

为了进一步提高肺部医学影像辅助诊断的准确性,提出一种高斯滤波增强技术融合最大类间方差法对肺部CT影像进行分割和计算病变面积占比的算法。首先对原始图像采用高斯低通滤波运算去除噪声和杂质并使用MSVSR提高图像质量,然后通过最大类间方差法将图像目标和背景分割出来,再将二值化图像一分为二,一方面采用高斯高通滤波运算锐化磨玻璃影和病变肺实质,另一方面使用HED将肺轮廓提取出来,最后计算出病变区域与肺轮廓面积占比。临床试验数据表明,本文算法不仅可以去除伪影和噪声,还能够最大限度地保留临床意义上的图像特征信息,具有较高的准确性,可以为临床研判肺部疾病严重程度与医疗诊治提供帮助。

关键词：高斯滤波最大类间方差肺部疾病边缘检测辅助诊断